• A clinicopathologic study of 141 cases compared with 916 nonmediastinal large B-cell lymphomas, a GELA ("Groupe d'Etude des Lymphomes de l'Adulte") study. (springer.com)
  • Angioimmunoblastic T-cell lymphoma (AITL), one of the most common PTCL entities, comprises neoplastic cells with a molecular signature similar to normal follicular helper T cells, and this cellular derivation might account for several of the peculiar aspects of this disease. (nih.gov)
  • Some types of slow-growing (indolent) B--cell lymphomas can change into DLBCL. (cancer.ca)
  • When DLBCL develops in a testicle, radiation therapy may be given to the other testicle to prevent the spread of lymphoma cells. (cancer.ca)
  • People with DLBCL that doesn't go away with treatment or that comes back after other treatments may be offered immunotherapy called CAR T-cell therapy. (cancer.ca)
  • DLBCL occurs in both men and women although it is slightly more prevalent in men, according to the Lymphoma Research Foundation . (healthcentral.com)
  • BIA-ALCL is not breast cancer-it is a type of non-Hodgkin's lymphoma (cancer of the immune system). (fda.gov)
  • They represent the commonest type of T-cell lymphomas in adults and the second most common form of extranodal non-Hodgkin's lymphoma. (frontiersin.org)
  • That's why it's best, if possible, to see a hematologist-oncologist who often treats people with lymphoma. (webmd.com)
  • At support groups, you can ask questions and hear about the experiences of other people with lymphoma. (nccn.org)
  • Y. Y. Hwang and R. H. S. Liang, "An Update in Management of Noncutaneous T-Cell Lymphomas," Advances in Hematology , vol. 2010, Article ID 424786, 6 pages, 2010. (hindawi.com)
  • T-cell neoplasms encompass a heterogeneous group of relatively rare disease entities. (nih.gov)
  • B-cell lymphomas are a heterogeneous group of diseases that can arise at different stages of B-cell development, often as a result of errors in the cells' unique ontogeny. (biomedsearch.com)
  • Non-Hodgkin lymphoma (NHL) is a collective term for a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment. (medscape.com)
  • Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. (drugbank.ca)
  • P eripheral T-cell lymphomas describes a diverse group of blood cancers that originate from T-cells, which may be at various stages of development. (lymphomation.org)
  • Of all cancers involving the same class of blood cell, 8% of cases are mature T cell lymphomas. (wikipedia.org)
  • Likewise, a recent study suggests that high dose therapy and autologous stem cell transplantation results in favorable outcomes for elderly patients with Non-Hodgkin's Lymphoma. (wikipedia.org)
  • Autologous stem cell transplantation is feasible for selected patients with enteropathy-associated T-cell lymphoma and can yield durable disease control in a significant proportion of these patients. (wikipedia.org)
  • After the lymph nodes shrink again or the disease gets less bulky, we typically offer patients an autologous stem cell transplantation procedure and can salvage probably about 50 percent of relapsed patients. (lymphoma.org)
  • These cancerous T-cells are a possible consequence of refractory cases of coeliac disease or in chronic, untreated cases in genetically susceptible individuals. (wikipedia.org)
  • The inhibition of this pathway can be induced by a drug known as NEMO Binding Domain, or NBD, a peptide causing increased cell death of malignant lymphocytes. (wikipedia.org)
  • long-term antigen stimulation is thought, through cytokine networks, to induce an inflammatory response with T-cell proliferation, leading to a clonal malignant T-cell with continuous expansion. (frontiersin.org)
  • Disease in which malignant cells form in the lymph system. (dmoztools.net)
  • Spontaneous remissions have been documented, most commonly in patients with low-grade lymphomas. (medscape.com)
  • An information, research and support resource for patients and caregivers dealing with non-Hodgkin's lymphoma. (dmoztools.net)
  • See Coeliac Disease, HLA-DQ, HLA DR3-DQ2) A DQ isoform that appears to be responsible for EATL in the overwhelming number of cases is highly effective at presenting a proteolytically protected region of α2-gliadin to T-cells, constant over-stimulation of T-cell eventually results in neoplastic growth. (wikipedia.org)
  • These are large cells that are different in size and shape and what really defines this disease is a uniform expression of a special marker on the lymphoma cells called CD30. (lymphoma.org)
  • Table 2, below, summarizes various types of cluster designations and their representative cells. (medscape.com)
  • The Lymphoma Research Foundation's mission is to eradicate lymphoma and serve those impacted by this blood cancer. (lymphoma.org)
  • Targeted therapy uses drugs to target specific molecules (such as proteins) on the surface of cancer cells. (cancer.ca)
  • By targeting these molecules, the drugs stop the growth and spread of cancer cells while limiting harm to normal cells. (cancer.ca)
  • Resources for dealing with Burkitts Lymphoma, a rare form of cancer. (dmoztools.net)
  • T-cell lymphomas are rare, and we try to approach new diagnoses with at least a little skepticism. (lymphomation.org)
  • It is the most common type of non-Hodgkin's lymphoma (NHL), comprising up to one-third of new NHL diagnoses in the United States. (healthcentral.com)