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  • murine
  • The objective of our study was established the effect of the bovine IFN-τ on human (SiHa) and murine (BMK-16/myc) cells transformed with HPV 16 and evaluates the antitumor effect in a murine tumor model HPV 16 positive. (jcancer.org)
  • We determine that bovine IFN-τ has antiproliferative effects, pro-apoptotic activity and induces repression of viral E6 and E7 oncogenes (time- and dose-dependent) on human and murine cells transformed with HPV 16 similar to the effects of IFN-β. (jcancer.org)
  • 1999
  • Caspase inhibitors block the retinal ganglion cell death following optic nerve transection (1999) Chaudhary P et al. (naver.com)
  • mechanism
  • There are few clinical trials indicating type-l IFNs efficacy in HTLV-I infected patients,[ 1 ] nevertheless a few studies have focused on antiviral mechanism of alpha IFNs on HTLV-I.[ 2 , 3 ] Here we report the reducing effect of IFN-α 2b (PDferon ® -B) on released particles of HTLV-I by HTLV-I transformed MT2 cell line. (biomedcentral.com)
  • less
  • One such cell line, GP6ac, which reverts to a less transformed phenotype when treated with RA, exhibited a 3-4-fold increase in surface EGF receptors with prolonged (2-5-day) RA exposure. (aacrjournals.org)
  • expression
  • There was no significant difference in expression of HTLV-I Gag, Tax and HBZ genes between cell lysates of treated and untreated MT2 cells at both 12 and 36 hours post treatment. (biomedcentral.com)
  • among
  • Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. (naver.com)
  • surface
  • On labelling the surface of cells by lactoperoxidase catalysed radio-iodination, the absence of a labelled polypeptide analogous to the 250 K (LETS) glycoprotein was noted. (microbiologyresearch.org)
  • The 293 cells were fixed in 4% paraformaldehyde and arrayed on a 12-well (5 mm) adhesive coated slide, with each wellis surface specifically treated to enhance cellular attachment and to minimize background staining. (nordicbiosite.com)
  • factor
  • Ciliary neurotrophic factor is an axogenesis factor for retinal ganglion cells (1998) Jo S.A et al. (naver.com)
  • treatment
  • At 12 hours post treatment, released Virus titer was not changed in supernate of treated cells while a significant decrease in viral particles was observed in collected supernate of treated cells at 36 hours after treatment with IFN-α 2b . (biomedcentral.com)