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  • field flow fraction
  • This note introduces the versatile size-separation technique of field flow fractionation (FFF) and its combination with ICP-MS. This coupling means that the size and elemental composition of complex, polydisperse and chemically heterogeneous inorganic engineered nanoparticles (ENPs) can be determined. (selectscience.net)
  • The Postnova model 3310 viscometer detector is a state-of-the-art intrinsic viscosity detector for Field-Flow Fractionation (FFF) and Size Exclusion Chromatography (GPC/SEC). It is based on the proven Wheatstone-Bridge design for measuring the intrinsic viscosity of macromolecules in solution. (norlab.fi)
  • biology
  • A fundamental of cell biology is the biogenesis and maintenance of intracellular organelles. (sigmaaldrich.com)
  • Molecular Biology of the Cell. (wikipedia.org)
  • In cell biology, an organelle (/ɔːrɡəˈnɛl/) is a specialized subunit within a cell that has a specific function. (wikipedia.org)
  • His initial research focused on experimental embryology, and soon his interest shifted to cell biology under the influence of Arthur Pollister. (wikipedia.org)
  • At Rockefeller University he made his most groundbreaking achievements in cell biology. (wikipedia.org)
  • In biology, autolysis, more commonly known as self-digestion, refers to the destruction of a cell through the action of its own enzymes. (wikipedia.org)
  • In a 2009 biographical memoir, Carol L. Moberg and Steinman wrote that "Zanvil Cohn may be most remembered as the founder of modern macrophage biology and for leading the shift in mid-twentieth-century research from bacterial cells to host-parasite relationships. (wikipedia.org)
  • The prize was granted for his innovations in electron microscopy and cell fractionation which together laid the foundations of modern molecular cell biology, the most notable discovery being the ribosomes of the endoplasmic reticulum - which he first described in 1955. (wikipedia.org)
  • In 1970, he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Renato Dulbecco winner of 1975 Nobel Prize in Physiology or Medicine "for discoveries concerning the functional organization of the cell that were seminal events in the development of modern cell biology", related to his previous research carried out at the Rockefeller Institute for Medical Research. (wikipedia.org)
  • Palade was the first Chairman of the Department of Cell Biology at Yale University. (wikipedia.org)
  • membrane
  • The cell membrane is broken through different mechanisms. (emailwire.com)
  • membrane protein complexes: photosystem I, ATP synthase large DNA and protein complexes: nucleosome centriole and microtubule-organizing center (MTOC) cytoskeleton flagellum nucleolus stress granule germ cell granule neuronal transport granule Eukaryotic cells are structurally complex, and by definition are organized, in part, by interior compartments that are themselves enclosed by lipid membranes that resemble the outermost cell membrane. (wikipedia.org)
  • Other related structures: cytosol endomembrane system nucleosome microtubule cell membrane Prokaryotes are not as structurally complex as eukaryotes, and were once thought not to have any internal structures enclosed by lipid membranes. (wikipedia.org)
  • In field-flow fractionation the field can be asymmetrical flow through a semi-permeable membrane, gravitational, centrifugal, thermal-gradient, electrical, magnetic etc. (wikipedia.org)
  • A lysosome is a membrane-bound organelle found in nearly all animal cells. (wikipedia.org)
  • Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism. (wikipedia.org)
  • Sonicator
  • There are often many different names for the same piece of mechanical homogenizing equipment, including Cell Lysor, Disperser, High Shear Mixer, Homogenizer, Polytron, Rotor Stator Homogenizer, Sonicator or Tissue Tearor. (wikipedia.org)
  • nucleus
  • The prokaryotic cell, so named because it lacks a discrete nucleus, is found in bacteria and blue-green algae. (modernbio.com)
  • The eukaryotic cell, by definition, has a nucleus that contains most of the cell's DNA. (modernbio.com)
  • In the nucleus of a typical eukaryotic cell, individual chromosomes can be identified only during cell division. (modernbio.com)
  • The event of chromatolysis is also characterized by a prominent migration of the nucleus towards the periphery of the cell and an increase in the size of the nucleolus, nucleus, and cell body. (wikipedia.org)
  • Peripheral chromatolysis is essentially the reverse of central chromatolysis, in which the disintegration of Nissl bodies is initiated at the periphery of the neuron and extends inwards towards the nucleus of the cell. (wikipedia.org)
  • Peripheral chromatolysis has been observed to occur in lithium-induced chromatolysis and it could be useful in investigating and countering the hypothesis that waves of enzymatic activity always progress from the perinuclear area, or the area situated around the nucleus, to the peripheral of the cell. (wikipedia.org)
  • Enzymes
  • It involves grinding of cells in a suitable medium in the presence of certain enzymes with correct pH, ionic composition, and temperature. (wikipedia.org)
  • These enzymes are released due to the cessation of active processes in the cell, not as an active process. (wikipedia.org)
  • In the food industry, autolysis involves killing yeast and encouraging breakdown of its cells by various enzymes. (wikipedia.org)
  • Lysosomes contain a variety of enzymes, enabling the cell to break down various biomolecules it engulfs, including peptides, nucleic acids, carbohydrates, and lipids. (wikipedia.org)
  • Lysosomes are sacs of enzymes within cells that digest large molecules and pass the fragments on to other parts of the cell for recycling. (wikipedia.org)
  • If one of these enzymes is defective, because of a mutation, the large molecules accumulate within the cell, eventually killing it. (wikipedia.org)
  • reagents
  • In November 2015, Merck KGaA acquired Sigma-Aldrich Co. LLC (U.S.), a developer of reagents and kits of cell-based research. (marketsandmarkets.com)
  • The Latin America Cell Fractionation market is broadly categorized on the basis of Product into Consumables, Reagents, Beads, Disposables and Instruments. (emailwire.com)
  • lysosomes
  • Ambroxol triggers the secretion of lysosomes from cells by inducing a pH-dependent calcium release from acidic calcium stores. (wikipedia.org)
  • processes
  • In 1952, research further supported the role of chromatolysis in changing the physiology of cells during cell death processes in embryo development. (wikipedia.org)
  • The lysosome is commonly referred to as the cell's recycling center because it processes unwanted material into substances that the cell can use. (wikipedia.org)
  • citation needed
  • citation needed] Therapeutic erythrocytapheresis is commonly used to remove red blood cells in patients experiencing sickle cell crisis. (wikipedia.org)
  • citation needed] While most cell biologists consider the term organelle to be synonymous with "cell compartment", other cell biologists choose to limit the term organelle to include only those that are containing deoxyribonucleic acid (DNA), having originated from formerly autonomous microscopic organisms acquired via endosymbiosis. (wikipedia.org)
  • 2016
  • ReportsWeb.com has announced the addition of the "Global Cell Fractionation Industry 2016 Market Research Report", the report focuses on global major leading industry players with information such as company profiles, product picture and specification. (pitchengine.com)
  • The 2016 Market Research Report on Global Cell Fractionation Industry is a professional and in-depth study on the current state of the Cell Fractionation industry. (pitchengine.com)
  • The Latin America Cell Fractionation Market was worth USD 189 million in 2016 and estimated to be growing at a CAGR of 10.2%, to reach USD 307 million by 2021. (emailwire.com)
  • buffer
  • 1. I sociated the cell suspension (in Tris-HCl buffer pH 7.9), centrifuged the samples (5 min, 2000 g) and the Cell free extract was not clear. (protocol-online.org)
  • biologist
  • Albert Claude (24 August 1899 - 22 May 1983) was a Belgian medical doctor and cell biologist who shared the Nobel Prize in Physiology or Medicine in 1974 with Christian de Duve and George Emil Palade. (wikipedia.org)
  • Zanvil Alexander Cohn (November 16, 1926 - June 28, 1993) was a cell biologist and immunologist who upon his death was described by the New York Times as being "in the forefront of current studies of the body's defenses against infection. (wikipedia.org)
  • November 19, 1912 - October 8, 2008) was a Romanian-American cell biologist. (wikipedia.org)
  • Described as "the most influential cell biologist ever", in 1974 he was awarded the Nobel Prize in Physiology and Medicine along with Albert Claude and Christian de Duve. (wikipedia.org)
  • Palade is survived by his wife Marilyn Farquhar, a cell biologist at the University of California, San Diego, and a daughter and son from his first marriage. (wikipedia.org)
  • particles
  • A sorting apparatus and method for fractionating and simultaneously viewing individual microstructures, such as free cells, viruses, macromolecules, or minute particles in a fluid medium. (patentgenius.com)
  • Field-flow fractionation, abbreviated FFF, is a separation technique where a field is applied to a fluid suspension or solution pumped through a long and narrow channel, perpendicular to the direction of flow, to cause separation of the particles present in the fluid, depending on their differing "mobilities" under the force exerted by the field. (wikipedia.org)
  • Field flow fractionation is based on laminar flow of particles in a solution. (wikipedia.org)
  • neuronal
  • Chromatolysis is still used as a term to distinguish the particular apoptotic process in the neuronal cells, where Nissl substance disintegrates. (wikipedia.org)
  • process
  • The process he described now fits with the relatively new term, apoptosis, to describe cell death. (wikipedia.org)
  • From observing the regression of ovarian follicles in mammals, it was argued that a necessary cellular process existed to counterbalance the proliferation of cells by mitosis. (wikipedia.org)
  • The process of Nissl dissolution is less apparent toward periphery of the cell body of the neuron, where normal-looking Nissl bodies may be present. (wikipedia.org)
  • In 1930, he discovered the process of cell fractionation, which was groundbreaking in his time. (wikipedia.org)
  • In other words, though autolysis resembles the active process of digestion of nutrients by live cells, the dead cells are not actively digesting themselves as is often claimed and as the synonym self-digestion of autolysis seems to imply. (wikipedia.org)
  • degradation
  • Hence, relieving the cell from accumulating degradation products is a proposed mechanism by which this drug may help. (wikipedia.org)