Cell DeathApoptosisCaspasesNecrosisProto-Oncogene Proteins c-bcl-2MitochondriaCaspase 3Caspase Inhibitorsbcl-2-Associated X ProteinCytochromes cSignal TransductionCell SurvivalCaspase 9Apoptosis Regulatory ProteinsAutophagyDNA FragmentationCause of DeathCaspase 8Antigens, CD95Apoptosis Inducing FactorEnzyme ActivationReactive Oxygen SpeciesIn Situ Nick-End LabelingPoly(ADP-ribose) PolymerasesCell Line, TumorCells, CulturedAmino Acid Chloromethyl KetonesMembrane Potential, Mitochondrialbcl-X ProteinApoptotic Protease-Activating Factor 1Cysteine Proteinase InhibitorsCaspase 7Fas Ligand ProteinReceptor-Interacting Protein Serine-Threonine KinasesProto-Oncogene ProteinsBH3 Interacting Domain Death Agonist ProteinTumor Suppressor Protein p53Cell Linebcl-2 Homologous Antagonist-Killer ProteinCytochrome c GroupCaspase 1DeathNeuronsInhibitor of Apoptosis ProteinsLanatosidesCysteine EndopeptidasesBlotting, WesternModels, BiologicalReceptors, Death DomainAntineoplastic AgentsTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alphaOxidative StressEnzyme InhibitorsStaurosporineJurkat CellsMice, Inbred C57BLTumor Cells, CulturedMice, KnockoutDNA DamageTime FactorsEndoplasmic ReticulumLysosomesGranzymesTransfectionRNA, Small InterferingMembrane ProteinsJNK Mitogen-Activated Protein KinasesCarrier ProteinsReceptors, Tumor Necrosis FactorHydrogen PeroxideCalpainMutationHelminth ProteinsHeLa CellsCell NucleusNeoplasmsDose-Response Relationship, DrugRNA InterferenceMembrane GlycoproteinsProteinsFlow CytometryMolecular Sequence DataPoly Adenosine Diphosphate RiboseMyeloid Cell Leukemia Sequence 1 ProteinCell ProliferationNerve DegenerationProtein Synthesis InhibitorsAcetylcysteineUp-RegulationU937 CellsRNA, MessengerDown-RegulationCathepsinsDeath, Sudden, CardiacDisease Models, AnimalGene Expression RegulationNeuroprotective AgentsCaenorhabditis elegans ProteinsMice, Transgenic