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  • dilution
  • A measurement adheres to proportionality when a change in the input parameter (in this case, dilution fraction) is always accompanied by a change in the measurand (in this case cell number), and that change is always related by a constant multiplier. (nist.gov)
  • In cell counting, this fundamental principle implies that the measured cell number should be proportional to the dilution fraction under ideal experimental conditions. (nist.gov)
  • The performance metric derived from the experimental and statistical framework characterizes the entire cell count measurement process, including the measurement platform, method specific factors such as dilution steps and sampling, and the specific cell preparation measured. (nist.gov)
  • Sources of error in manual WBC counting are due largely to variance in the dilution of the sample and the distribution of cells in the chamber, as well as the small number of WBCs that are counted. (encyclopedia.com)
  • quantify
  • To quantify the performance metric for a counting measurement process, we assess two main properties to determine the overall quality of the measurement: proportionality and precision. (nist.gov)
  • To quantify the number of cells in a culture, the cells can be simply plated on a petri dish with growth medium. (wikipedia.org)
  • It is therefore extensively used in experiments aiming to quantify the number of cells resisting drugs or other external conditions (for instance the Luria-Delbrück experiment or the gentamicin protection assay). (wikipedia.org)
  • acceptable
  • Automated cell counters may not be acceptable for counting WBCs in other body fluids, especially when the number of WBCs is less than 1000/ μ L or when other nucleated cell types are present. (encyclopedia.com)
  • atypical
  • For example, an elevated WBC count with an absolute increase in lymphocytes having an atypical appearance is most often caused by infectious mononucleosis . (encyclopedia.com)
  • When the electronic WBC count is abnormal or a cell population is flagged, meaning that one or more of the results is atypical, a manual differential is performed. (encyclopedia.com)
  • increase
  • The following medicines may help increase WBC counts. (cancer.ca)
  • When you move to a higher altitude, your RBC count may increase for several weeks because there's less oxygen in the air. (healthline.com)
  • Certain drugs like gentamicin and methyldopa can increase your RBC count. (healthline.com)
  • There are several diet and lifestyle changes that people can make to help the body increase the number of red blood cells. (medicalnewstoday.com)
  • Drug information on this drug shown to reduce the amount of virus circulating in the body and to increase CD4 cell counts. (dmoztools.net)
  • HELP
  • For example, the complete blood count can help a physician to determine why a patient feels unwell and what to do to help. (wikipedia.org)
  • estimate
  • Although this method can be time consuming, it gives an accurate estimate of the number of viable cells (because only they will be able to grow and form visible colonies). (wikipedia.org)
  • WBCs
  • Any immature WBCs are included in the differential count of 100 cells, and any inclusions or abnormalities of the WBCs are reported. (encyclopedia.com)
  • similarly
  • Highly scattered experimental data with average cell numbers fitting well to proportionality would similarly reduce the overall robustness of the measurement process. (nist.gov)
  • high
  • A high RBC count may be a result of sleep apnea , pulmonary fibrosis , and other conditions that cause low oxygen levels in the blood. (healthline.com)
  • measure
  • The performance metric provides a relative measure of accuracy for cell counting by assessing closeness of agreement between the obtained cell count data and the fundamental property of proportionality. (nist.gov)
  • Several tests like the PortaSCC milk test and The California mastitis test provides a cow-side measure of somatic cell count. (wikipedia.org)
  • A Coulter counter is an appliance that can count cells as well as measure their volume. (wikipedia.org)
  • A CSF cell count is a test to measure the number of red and white blood cells that are in cerebrospinal fluid (CSF). (medlineplus.gov)
  • Explain that cells shed by a metastatic castration-resistant prostate cancer into the blood may be a robust measure of how well treatment is working. (medpagetoday.com)
  • measurement
  • We have developed a method to assess the overall quality of a cell counting measurement. (nist.gov)
  • This method does not require a reference material or "ground truth" cell number value and is independent of cell type and measurement technique/instrument. (nist.gov)