Cell CycleCell Line, TumorCell Cycle ProteinsApoptosisTumor Cells, CulturedTumor Suppressor Protein p53Cell DivisionCell ProliferationCell Cycle CheckpointsCaspasesApoptosis Regulatory ProteinsCell SurvivalSignal TransductionCaspase 3Proto-Oncogene Proteins c-bcl-2Tumor Necrosis Factor-alphaCell LineTumor Markers, BiologicalFlow CytometryG1 PhaseInhibitor of Apoptosis ProteinsCells, CulturedAntineoplastic AgentsTumor Suppressor ProteinsNeoplasms, ExperimentalTumor BurdenNeoplasmsRNA, MessengerBlotting, WesternMitosisTransfectionGene Expression Regulation, NeoplasticTime FactorsPhosphorylationCyclinsS PhaseMice, NudeNeoplasm ProteinsDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinMolecular Sequence DataCyclin-Dependent Kinase Inhibitor p21Reverse Transcriptase Polymerase Chain ReactionImmunohistochemistryRNA, Small InterferingMutationGenes, Tumor SuppressorProto-Oncogene ProteinsDown-RegulationEnzyme ActivationXenograft Model Antitumor AssaysProtein-Serine-Threonine KinasesMice, Inbred C57BLG2 PhaseDNA DamageDNA-Binding ProteinsMice, Inbred BALB CNeoplasm MetastasisNeoplasm TransplantationDose-Response Relationship, DrugColonic NeoplasmsBreast NeoplasmsRetinoblastoma ProteinMammary Neoplasms, ExperimentalAdenocarcinomaBrain NeoplasmsEnzyme InhibitorsHeLa CellsBase SequenceTransplantation, HeterologousModels, BiologicalX-Linked Inhibitor of Apoptosis ProteinTranscription FactorsMitochondriaCell Transformation, NeoplasticCyclin-Dependent Kinase Inhibitor p27Up-RegulationCarcinoma, Ehrlich TumorNeovascularization, PathologicCell NucleusWilms TumorCaspase 9Gene ExpressionAntigens, NeoplasmGene Expression RegulationDNA, NeoplasmCaspase InhibitorsG2 Phase Cell Cycle CheckpointsFas Ligand ProteinFibroblastsCell DifferentiationCell DeathCaspase 8CASP8 and FADD-Like Apoptosis Regulating ProteinMenstrual CycleFibrosarcomaTranscription, GeneticTumor MicroenvironmentMice, SCID