Cell biology cell survival. Medical search. Frequent questions

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With the advances in molecular biology, a new classification era of these organisms arises, with the development of sequencing of specific genes based initially on a small sequence of the 18 s gene, or SSU-rDNA [ 10 ]. (hindawi.com)
He then moved to the Department of Biochemistry and Molecular Biology at Michigan State University where he worked with Christoph Benning as a postdoc on the biochemistry and molecular genetics of plant lipids and the molecular mechanisms of intracellular lipid transport. (bnl.gov)
MD and/or Ph.D. in a relevant field and have training in cell and molecular biology, Nanotechnology, and/or brain biology. (postdocjobs.com)
The intriguing realm of porifera, known as sponges, beckons exploration in molecular biology. (lu.se)
The dynamic world of porifera, commonly known as sponges, presents a captivating avenue for exploration within molecular biology. (lu.se)
Undoubtedly, advances in molecular biology will allow scientists to determine the exact genomic aberration responsible for each specific neoplasm. (medscape.com)
CDC's Newborn Screening and Molecular Biology Branch has the only laboratories in the world that work with programs in every U.S. state and in more than 80 countries to ensure that newborn screening tests are accurate. (cdc.gov)

For the current analysis, the research team measured the extent of genomic loss of 9p24.1 in the cancer cells of patients with HNSC-HPVneg as captured by the National Cancer Institute's massive database on cancer cell genetics, the Cancer Genome Atlas, as well as in patient datasets from a company called Caris Life Sciences. (sciencedaily.com)
The essential biochemistry, genetics, cell biology, and metabolic pathways underlying the survival and success of all living organisms. (queensu.ca)

What so many people have been working on for so long was surprisingly easy, after all," says Stina Oredsson, biology researcher at Lund University. (lu.se)
Now, a research group at Lund University has succeeded in finding a drug candidate that binds to the protein, something that has been shown to affect the growth capability of leukemia cells. (lu.se)
It seems that cancer cells may increase the number of aquaporins to enhance their own survival and increase their spreading ability, says Karin Lindkvist, professor of cell biology at Lund University and structural biology researcher. (lu.se)

In addition, we examined whether these substrates will support differentiation of retinal pigmented epithelial cells, an important, clinically relevant cell type that is currently in clinical trials for eye disease. (ca.gov)
Human Papillomavirus (HPV) Infection Human papillomavirus (HPV) infects epithelial cells. (msdmanuals.com)
Signaling through CysLT1R results in increased proliferation, survival and migration of intestinal epithelial cells, whereas signaling through CysLT2R leads to differentiation of colorectal cancer cells. (lu.se)

download Caspases: Their Role in Cell Death and Cell Survival 's now about used and specified. (palemoon.com)
A contemporary Douglas name-checked Given to Culver City Community Hospital, across the download Caspases: Their Role in Cell Death and Cell Survival from MGM, where she saw not. (palemoon.com)
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Results from this work will significantly advance our understanding of how the interplay between cell death and cell survival is regulated, which is still poorly understood despite its considerable biological importance. (edu.au)

Yu L, Fan J, Xu C (2019) Peroxisomal fatty acid β-oxidation negatively impacts plant survival under salt stress. (bnl.gov)

Developmental Cell. (wikipedia.org)
UC Irvine's Maksim Plikus, assistant professor of developmental & cell biology, and Qing Nie, professor of mathematics, led the effort. (universityofcalifornia.edu)

The strongest link between the number of TILs and overall survival was for patients with high-grade serous ovarian cancer, which is the most common and most lethal histological type, or histotype, of the disease. (shu.edu)
The five-year overall survival rate was 38.0 percent among patients whose tumors contained T cells and 4.5 percent among patients whose tumors contained no T cells in islets. (shu.edu)
Panels A and B show Kaplan-Meier curves for the duration of progression-free survival and overall survival, respectively, according to the presence or absence of intratumoral T cells in 174 patients with stage III or IV epithelial ovarian cancer and complete, partial, or no response to therapy. (shu.edu)
and overall survival will not be measured. (medscape.com)
Overall survival is a secondary outcome. (medscape.com)
Overall survival and QoL will not be tracked. (medscape.com)
Kaplan-Meier and Cox regression analyses were used to compare progression free survival (PFS) and overall survival (OS) between the groups. (springer.com)
Results: High PDCD1 methylation (mPDCD1) was associated with a significantly shorter overall survival after surgical resection in both the discovery (HR = 2.24 [95% CI: 1.08-4.64], p = 0.029) and the validation cohort (HR = 1.54 [95% CI: 1.08-2.21], p = 0.017). (uni-koeln.de)

Thus we considered the hematopoietic system and found that seven days after poly injection, the number of blood cells in peripheral blood decreased drastically. (biomedcentral.com)
Hematopoietic stem cell transplantation (HSCT) involves the intravenous infusion of hematopoietic stem cells in order to reestablish blood cell production in patients whose bone marrow or immune system is damaged or defective. (medscape.com)
GFI1B-D262N promoted myelomonocytic versus erythroid output from primary human hematopoietic precursors and enhanced cell survival of both normal and MDS derived precursors. (lu.se)

Survival of motor neuron or survival motor neuron (SMN) is a protein that in humans is encoded by the SMN1 and SMN2 genes. (wikipedia.org)
Life has no real purpose, dude - it is about the survival of the genes in us - feeding, fending, fleeting and fathering - just live through it and get it over with. (chick.com)
9p houses many genes, including those that encode interferons, a set of immune system signaling proteins that can trigger attack on cancer cells, at a location (locus) called 9p21. (sciencedaily.com)
Tumorigenesis is a multi-step process in which a normal cell acquires changes in a number of critical cancer causing genes. (umassmed.edu)
Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now discovered that the two micro RNA molecules miR-1 and miR-133 in the adult heart inactivate two genes that normally force cell division. (mpg.de)
Indeed, the expression of the genes for the oncostatin M receptor and the FGF receptor 1 increased in these cells, and with it the number of receptor molecules. (mpg.de)
This includes the analysis of genes in germline stem cell proliferation and differentiation. (ncl.ac.uk)

The pheromone signalling pathway of baker's yeast belongs to a class of MAPK (mitogen-activated protein kinase) signalling pathways, which in eukaryotes commonly play a key role in the transmission and translation of extracellular stimuli into intracellular responses such as cell differentiation, proliferation or stress responses. (mpg.de)
This surface proved to be efficient at supporting growth of undifferentiated hESC as well as differentiation of useful cell types. (ca.gov)
There is a critical need for new technologies to facilitate growth and differentiation of human embryonic stem cells (hESC) using clinically acceptable, animal-free reagents. (ca.gov)
Our approach is to first understand how hESC interact with extracellular matrix materials by analyzing candidate adhesive substrate proteins and integrin receptors that mediate attachment, survival, proliferation and differentiation. (ca.gov)

Consistent with this notion, we have found that Smurf2-deficient mouse embryonic fibroblasts exhibit delayed senescence entry and enhanced potential to become immortalized in culture, while Smurf2-deficient mice show increased susceptibility to various types of cancer, including B-cell lymphoma, hepatocellular carcinoma, adenocarcinoma in small intestine and soft tissue sarcoma. (umassmed.edu)
We proposed to develop novel, well-defined, synthetic extracellular matrices that support survival and proliferation of human embryonic stem cells. (ca.gov)
Finally, we identified a cyclic RGD peptide that supports growth of human embryonic stem cells. (ca.gov)
We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. (ncl.ac.uk)
Although meningiomas commonly arise in locations where meningothelial cells are found, the embryonic origin of intraventricular and pulmonary meningiomas are intriguing. (medscape.com)

Nature Structural Biology. (wikipedia.org)
In contrast to what had been the dominant theory in the field, we revealed a far more chaotic process," says James R. Williamson, PhD , a professor in the Department of Integrative Structural & Computational Biology at Scripps Research. (scripps.edu)
This shows that we now can examine in detail how RNAs fold while they are being synthesized and proteins are assembling on them," says first author Olivier Duss, PhD, a postdoctoral research fellow in the Department of Integrative Structural & Computational Biology at Scripps Research. (scripps.edu)
We use a combination of biochemical, cell biology, structural biology and medicinal chemistry approaches to understand the precise molecular mechanisms that control apoptosis. (edu.au)
2] The arachnoid cells have several proposed functions, including acting as a structural barrier with cellular wrapping/ensheathing, acting as a conduit for cerebrospinal fluid (CSF) drainage/absorption into dural sinuses/veins (arachnoid villi), epithelial-like/secretory functions, monocytelike functions, trophic support and byproduct detoxification for glial and neuronal cells, and participation in reactive/reparative processes. (medscape.com)

Our projects encompass studies on basic tumor biology as well as translational and preclinical studies with the aim to find novel treatments. (lu.se)

For 2023, the IDF Research Grant Program is awarding more than $190,000 in support of five projects that advance the diagnosis, knowledge of underlying biology, and potential treatments for primary immunodeficiencies (PI). (primaryimmune.org)

The problem of classifying meningioma is that arachnoidal cells may express both mesenchymal and epithelial characteristics. (medscape.com)
Both non-neoplastic meningothelial cells and meningiomas possess mixed features of epithelial and mesenchymal cells. (medscape.com)

Survival analysis and time receiver operating characteristic curves indicate that the prognostic signature has strong predictive performance. (techscience.com)
The influence of various extensively studied prognostic factors on survival was assessed by multivariate analysis. (springer.com)
In the current study, DNA promoter methylation of programmed cell death 1 (PDCD1, PD-1) was evaluated as a prognostic biomarker in HNSCC patients. (uni-koeln.de)
Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). (lu.se)

Here, we show that vinculin null (vin −/− ) cells and cells expressing a vinculin Y822F mutant have increased survival due to up-regulated activity of extracellular signal-regulated kinase (ERK). (rupress.org)
Our recent studies as well as others indicate that senescent cells change their secretory patterns of cytokines, chemokines, growth factors, extracellular matrix proteins and proteases. (umassmed.edu)
The research program integrates brain biology, Immunology, and extracellular microvascular biology with an emphasis on molecular and cellular mechanism underlying how plant exosomes contribute to brain function via gut/brain/liver axis. (postdocjobs.com)

Thus, vinculin regulates survival and motility via ERK by controlling the accessibility of paxillin for FAK interaction. (rupress.org)

We functionally characterize novel mTOR regulators by means of biochemistry, cell biology and in vivo . (uibk.ac.at)

These proteins provide a selective conduction of ions across cellular membranes, which is crucial for cell survival. (surrey.ac.uk)
Although lysosomes perform a number of essential cellular functions, damaged lysosomes represent a potential hazard to the cell. (biorxiv.org)
The achievement, reported in Cell , reveals in unprecedented detail how strands of ribonucleic acid (RNA), cellular molecules that are inherently sticky and prone to misfold, are "chaperoned" by ribosomal proteins into folding properly and forming one of the main components of ribosomes. (scripps.edu)
For example, we investigate regulators which control mTOR activity and cellular survival under stress (Heberle & Razquin-Navas et al. (uibk.ac.at)
By developing novel tools and harnessing the power of metabolomics, proteomics and functional genomics, our lab will define 1) how the lysosome communicates with other cellular compartments to fulfill the metabolic demands of the cell under various metabolic states, 2) and how its dysfunction leads to rare and common human diseases. (stanford.edu)

Moreover, even when high-purity single-cell sorting can be achieved, viability after sorting is often low to moderate, especially for cell types that are particularly sensitive to hydrodynamic stress or low-density culture conditions (e.g., primary cells or pluripotent stem cell lines). (nature.com)
Accordingly, in contrast to organs with a high regenerative capacity, no divisible, regenerative stem cells are found in the heart. (mpg.de)
This is an important, unmet need in the field and development of such a substrate would aid in moving stem cell therapies to the clinic. (ca.gov)
First, we characterized the cell surface receptors for matrix proteins on stem cells and identified specific proteins that will support adhesion and growth of the cells. (ca.gov)
Second, using an interdisciplinary approach, we developed a novel method to screen peptides from these proteins for their ability to support adhesion and proliferation of the stem cells. (ca.gov)
Based on our characterization of cell surface receptors for matrix proteins on stem cells completed in the first year, we went on to test specific, purified proteins that will support adhesion and growth of the cells. (ca.gov)
Second, using an interdisciplinary approach, we developed novel hydrogels using click chemistry that support adhesion and proliferation of the stem cells. (ca.gov)
The National Marrow Donor Program (NMDP), founded in 1986, and the World Marrow Donor Association (WMDA), founded in 1988, were established to (1) locate and secure appropriate unrelated-donor HSCT sources for patients by promoting volunteer donation of bone marrow and peripheral blood stem cells in the community and (2) promote ethical practices of sharing stem cell sources by need, rather than by geographic location of the donor. (medscape.com)
The purpose is to deliver chemotherapy, immunotherapy, and/or radiation to eliminate malignancy, prevent rejection of new stem cells, and create space for the new cells. (medscape.com)
Stem cell infusion is a relatively simple process that is performed at the bedside. (medscape.com)
Stem Cell Reports. (lu.se)

Fan J, Yu L, Xu C (2017) A Central Role for Triacylglycerol in Membrane Lipid Breakdown, Fatty Acid β-Oxidation, and Plant Survival under Extended Darkness. (bnl.gov)
Front Cell Infect Microbiol;7: 38, 2017. (bvsalud.org)

Survival Analyses of Patients with Ovarian Carcinoma, According to the Presence or Absence of Intratumoral T Cells. (shu.edu)
A comprehensive understanding of ovarian carcinoma survival prognosis by novel biomarkers. (cdc.gov)

C) Lower level of Smurf2 expression correlates with poor survival prognosis in patients with DLBCL. (umassmed.edu)
The immune-related gene signature effectively predicts the survival and immune infiltration of breast cancer patients and is expected to provide more effective immunotherapy targets for the prognosis prediction of breast cancer. (techscience.com)
We present novel data that show HNF4A protein expression does not confer favourable prognosis in papillary RCC, confirming our survival analysis with publicly available HNF4A RNA expression data. (lu.se)

The complex, apart from the "proper" survival of motor neuron protein, includes at least six other proteins (gem-associated protein 2, 3, 4, 5, 6 and 7. (wikipedia.org)
Furthermore, infusion of normal bone marrow cells rescued mice from death induced by loss of THOC5/Fms interacting protein. (biomedcentral.com)
Furthermore, mechanistically depletion of THOC5/Fms interacting protein causes the down-regulation of its direct interacting partner, THOC1 which may contribute to altered THO complex function and cell death. (biomedcentral.com)
The team will now be able to extend this research further to study not only the rest of ribosome assembly, which involves multiple RNA strands and dozens of proteins, but also the many other types of RNA-folding and RNA-protein interaction in cells. (scripps.edu)
Solomon plans to look at a protein on the circulating T cells' surfaces, called the T cell receptor (TCR), that he suspects differs in those with SOID and may explain their symptoms. (primaryimmune.org)
In people without PI, each T cell makes one version of TCR, and that version determines what protein or other biological molecule the T cell will recognize. (primaryimmune.org)
Our aim is to develop new reagents, including drugs that could target and inhibit the actions of the key pro-survival protein proteins that keep cancers alive. (edu.au)
This will be achieved through the use of Bcl-2 protein-selective reagents, which were engineered in the Fairlie laboratory, to profile melanoma cell lines, as well as samples from patients. (edu.au)
Scientists also added various protein extracts from animals to make the cells grow. (lu.se)
By understanding the structure of the protein , and how drugs attach to it, we are trying to comprehend how cancer cells respond to new drug candidates. (lu.se)

We perform molecular and functional studies of primary and metastatic tumor cells, as well as in vitro and in vivo drug testing using PDXs as model system. (lu.se)

Aquaporins are water channels found in the cell membranes. (lu.se)

A vinculin fragment (amino acids 811-1066) containing the paxillin binding site restored apoptosis and suppressed ERK activity in vin −/− cells. (rupress.org)
Transfection with paxillin Y31FY118F dominant-negative mutant in these cells inhibits ERK activation and restores apoptosis. (rupress.org)
Immune escape is mainly caused by histocompatibility complex (MHC) class I, abnormal antigen signaling mechanism, immunosuppressive components (such as HLA-G), Fas and its ligands to activate apoptosis and overexpression of other immunosuppressive molecules, such as lymphocyte activation gene 3 (LAG-3), T cell immunoglobulin and mucin domain 3 (TIM-3) ( Steven and Seliger, 2018 ). (techscience.com)
The best studied is apoptosis, a form of programmed cell death used by all multicellular organisms to eliminate cells that are damaged, no longer needed or which might become a threat to the organism. (edu.au)
Complementary projects in the lab focus on autophagy, a cell survival process that has significant cross-talk with apoptosis. (edu.au)
There is some evidence that Bcl-2 pro-survival proteins (which normally keep cells alive by inhibiting the cell death program of apoptosis) are expressed at unusually high levels in melanoma compared to normal melanocytes. (edu.au)
Communication between the cell survival pathway of autophagy and the cell death pathway of apoptosis is crucial for determining the best outcome for the cell, and ultimately its fate. (edu.au)

REC-4881, developed by Recursion, inhibits the MEK pathway, a prime mover in cancer cell biology. (medscape.com)
The second approach is to use either the new gene editing CRISPR/Cas9 technology or mass spectrometric/proteomics approaches (or both) to undertake screens to identify factors that can inhibit the cell death that occurs as a consequence of disarming the autophagy pathway through deletion of Beclin. (edu.au)

But in 2018, researchers in Lund started using different human proteins needed for cell survival in a cell culture medium. (lu.se)

From a biological point of view, there are arguments to support an early as well as a late initiation of RT: οn the one hand, an early start of RT could have a negative impact on survival due to reduced radiosensitivity secondary to postoperative hypoxia or due to the "second-impact" effect leading to a further deterioration of the clinical condition of an already compromised patient [ 19 , 20 ]. (springer.com)
In their studies on genetically modified mice, the Bad Nauheim researchers also found that in animals in which miR-1/133a was switched off, the heart muscle cells coped much better with hypoxia conditions (oxygen depletion), such as those that exist after a heart attack. (mpg.de)
In the experiment, the heart muscle cells from miR-1/133a knockout animals showed higher viability and survival in hypoxia,' Valussi said. (mpg.de)

Experimental Cell Research. (wikipedia.org)
Scientists working in basic, translational, and clinical cancer metabolism research are invited to join the Academy in New York on April 17th to discuss the intersection between cell signaling and metabolism. (nyas.org)
LA JOLLA, CA - A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes-the complex and evolutionarily ancient "molecular machines" that make proteins in cells and are essential for all life forms. (scripps.edu)
More generally, the research offers biologists a powerful new approach to the study of RNA molecules, hundreds of thousands of which are active at any given time in a typical cell. (scripps.edu)
I have been teaching a variety of courses here at Queen's for over 20 years, from introductory biology to the commercialization of biological research at the graduate level. (queensu.ca)
Dr. Xu's research group uses a combination of molecular genetic, cell biological, biochemical and physiological approaches to dissect the regulatory network governing lipid metaoblism, homoestasis and storage. (bnl.gov)
C. Xu established his own research program when he joined the Biology Department at Brookhaven National Laboratory in 2009. (bnl.gov)
Our research aims to identify the key Bcl-2 pro-survival proteins that are responsible for melanoma survival. (edu.au)
Researchers from Lund have developed a completely animal-free preparation for cell culture, a medium that can be used to grow human cells, including for cancer research. (lu.se)
This has sparked a lot of interest in many parts of Europe and also with the US Food and Drug Administration (US FDA), not least because it can be used to grow normal cells but also in cancer research. (lu.se)

Within both normal and cancerous cells, chromosomes are the 23 superstructures that house, organize, and protect the DNA code. (sciencedaily.com)
It took off in 1958 when researchers discovered that fetal bovine serum (FBS) was an additive that could make cells thrive, both normal and cancerous. (lu.se)

Specifically the study addresses HPV-negative head and neck squamous-cell (HNSC-HPVneg) carcinomas, the most common and lethal subtype of head and neck cancer with more 200,000 deaths globally per year. (sciencedaily.com)
The likelihood of copying errors is much greater during the reckless growth driven by fast-dividing cancer cells, say the authors, which explains the "extensive" chromosome copy number changes present in most HPV-negative head and neck squamous-cell carcinomas. (sciencedaily.com)
Background: Biomarkers that facilitate the prediction of disease recurrence in head and neck squamous cell carcinoma (HNSCC) may enable physicians to personalize treatment. (uni-koeln.de)
Squamous cell carcinoma comprises over 95% of oropharyngeal cancers. (msdmanuals.com)
90% of head and neck cancers are squamous cell (epidermoid) carcinomas. (msdmanuals.com)
Squamous cell carcinoma comprises over. (msdmanuals.com)

Researches with the Ovarian Tumor Tissue Analyses Consortium analyzed the CD8+ (cytotoxic T-cell) content of tumors from 5,500 patients and compared them with clinical outcome. (shu.edu)
For these patients, as the number of TILs in tumors increased there were corresponding improvements in survival. (shu.edu)
Looking at the other histologic types, CD+ positivity was correlated with survival among patients with endometrioid and mucinous tumors, but not for clear cell or low grade serous ovarian cancer. (shu.edu)
Antibodies only work if there are enough immune cells present to notice them, a state called "immune hot," with the field understanding little about why so many patients have too few immune cells near their immune cold tumors. (sciencedaily.com)
Meningiomas, as defined by the World Health Organization (WHO), are "meningothelial (arachnoid) cell neoplasms, typically attached to the inner surface of the dura mater," and these tumors fall into WHO grades I, II, and III. (medscape.com)
Discovery of novel strategies to inhibit treatment-resistant metastatic tumors can increase survival and decrease side effects for high-risk neuroblastoma patients. (lu.se)

Mutations in the X-linked Plp gene lead to dysmyelinating phenotypes and oligodendrocyte cell death. (rupress.org)
Cell engineering through gene editing is fundamentally a two-step bioprocess. (nature.com)

In this review, we present a current understanding of the functions of and distinctions between APRIL/BAFF signaling by their respective receptors expressed on particular B-cell subsets. (nih.gov)
We found that miR-1/133a suppresses two receptors on heart muscle cells. (mpg.de)
Conversely, overexpression of miR-1/133a caused the cells to terminate any cell division activity if we had previously induced it by administering the binding molecules of the two receptors, i.e. oncostatin and FGF,' explains Melissa Valussi, first author of the study. (mpg.de)
In this case, the heart muscle cells lost the ability to contract due to the unchecked activity of the two receptors and the animals suffered heart failure. (mpg.de)

I am a Professor in the Department of Biology at Queen's University. (queensu.ca)

Our hypothesis is that Bcl-2 pro-survival proteins provide a survival advantage for melanomas and might contribute to resistance to standard chemotherapeutic drugs. (edu.au)

With all current information, it is possible to speculate that the differences in amoebas could be associated with the presence or absence of flagella, developed with the expansion of these organisms to different substrates to seek favorable conditions promoting their survival, searching for nutrients from bacteria. (hindawi.com)
When I consider the cell, how it grows and divides, how one gives rise to two, how entire organisms can exist as a single cell, while the existence of others requires cooperation between trillions of them, I am impressed by their ability to persist in natural and unnatural environments, to proliferate and work cooperatively with others. (christianitytoday.com)

We used compound heterozygote mice to study the long-term fate of oligodendrocytes expressing either the jimpy or rumpshaker allele against a background of cells expressing a Plp -null allele. (rupress.org)
A) Lymphomas found in Smurf2-deficient mice have the characteristics of diffuse large B-cell lymphoma (DLBCL) and enhanced cell proliferation. (umassmed.edu)

Adhesion complexes (i.e., focal adhesions and focal complexes) and cell-cell contacts are specialized structures that harbor a large number of cytoskeletal proteins and one of the highest concentrations of signaling molecules in cells ( Ruoslahti and Obrink, 1996 ). (rupress.org)
Dysregulated signaling by TNFRSF members can promote B-cell survival and proliferation, causing autoimmunity and neoplasia. (nih.gov)
We also underscore how new findings and conceptual insights into TNFRSF signaling are facilitating the understanding of B-cell malignancies and autoimmune diseases. (nih.gov)
Precise signaling is crucial for the fitness of every living organism: whether during development or while communicating with a possible mating partner, only accurate transmission of received signals enables cells to trigger appropriate responses. (mpg.de)
Mycobacterium tuberculosis (M. tb) has two peptidyl-prolyl isomerases (Ppiases) PpiA and PpiB, popularly known as cyclophilin A and cyclophilin B. The role of cyclophilins in processes such as signaling, cell surface recognition, chaperoning, and heat shock response has been well-documented. (bvsalud.org)

Identification of a New Eight-Long Noncoding RNA Molecular Signature for Breast Cancer Survival Prediction. (cdc.gov)

Both enhanced survival and motility are critical to metastasis. (rupress.org)
The enhanced motility of vin −/− and vinY822F cells is also shown to be due to a similar mechanism. (rupress.org)

Led by researchers from NYU Grossman School of Medicine and UC San Diego Moores Cancer Center, the new study revolves around the human immune system, which can recognize cancer cells as abnormal and attack them. (sciencedaily.com)
Therefore a potential benefit pathologically to confirm the presence cells, which leads to abnormal differen- could be expected if we had a feasible or absence of gastritis and/or malignan- tiation of cells [3]. (who.int)

Cells lacking vinculin are highly metastatic and motile. (rupress.org)

Cancer cells hide from the system by hijacking "checkpoint" sensors that keep the immune cells from attacking normal cells. (sciencedaily.com)
CIBERSORT and TIMER algorithms confirmed that there are significant differences in tumor-infiltrating immune cells in different risk groups. (techscience.com)

This has been a very difficult thing to study in biology because it involves several distinct biological processes that are dependent on each other and have to be detected simultaneously. (scripps.edu)
In biological systems, random fluctuations of signals always lead to background noise, which can impede cell communication. (mpg.de)
There are more than biological principles inside cells. (christianitytoday.com)
Yet somehow I find that the cells I studied in graduate school and now teach my students about hold more than biological principles inside of them. (christianitytoday.com)
Molecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology New Delhi, India. (bvsalud.org)

Those with SIOD are unable to fight infection because their T cells, a type of white blood cell, don't work properly. (primaryimmune.org)
The first tests whether the thymocyte's TCR is capable of recognizing a foreign molecule, which ensures that released T cells will actually protect against infection. (primaryimmune.org)
If Solomon shows that the TCR repertoires of circulating T cells from individuals with SIOD are most similar to thymocytes from individuals without PI, this may explain both the susceptibility to infection and the autoimmunity seen in individuals with SIOD. (primaryimmune.org)

Anatomy29

Organisms11

Diseases24

Chemicals and Drugs61

Analytical, Diagnostic and Therapeutic Techniques and Equipment47

Phenomena and Processes60

Disciplines and Occupations17

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Humanities3

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Health Care15

Molecular Biology9

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Death And Cell Survival4

20191

Developmental Cell2

Overall survival8

Hematopoietic3

Genes7

Differentiation4

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Structural5

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20231

Mesenchymal2

Prognostic4

Extracellular3

Regulates survival1

Biochemistry1

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Stem11

20172

Ovarian Carcinoma2

Prognosis3

Protein10

Vivo1

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20181

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Squamous-cell6

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