Cell biology cell movement. Medical search. Frequent questions

The focus of my laboratory is the understanding of basic mechanisms that regulate the fate of stem cells within tissues. (ad-astra.ro)
Physiology can be investigated at the level of the whole body, organ systems, tissues and cells at the molecular level. (umanitoba.ca)
Non-muscle cell contractility is critical for tissues to adopt shape changes. (elifesciences.org)
The module will also discuss the developmental biology of these cells and tissues, in a section on embryology. (aber.ac.uk)
I have been interested in understanding leukocyte biology, specifically how leukocytes migrate to sites of cell death and how sterile inflammation damages tissues. (nikonsmallworld.com)
As an instructor, she taught histology , which is the study of the microscopic anatomy of cells and tissues. (asu.edu)
I then moved to UCL for my post doc, changing focus from single cells to cell-to-cell interaction, looking at early tumourgenesis in epithelial tissues. (cardiff.ac.uk)
It is surrounded by cells and tissues which push and pull it as they undergo movements and shape changes during development. (news-medical.net)
We measure cellular forces in cells and tissues with high spatial resolution using arrays of vertical nanowires. (lu.se)

Multiple researchers from other divisions in the department pursue projects in Cell Physiology & Pathophysiology. (umanitoba.ca)
Stress-response pathways play a key role in the patho-physiology and treatment of many diseases, including cancer.At almost every stage of the development of a tumour, cells are exposed to some form of stress. (southampton.ac.uk)
We strive for a detailed understanding of the interactions between cells and nanostructures with respect to cell behavior, cell physiology and cell mechanics. (lu.se)
Our goal is to understand in detail the interactions between cells and nanostructures such as nanowires and nanotubes with respect to cell behavior, cell physiology and cell mechanics. (lu.se)

The study of cells and how they work has led to many other studies in related areas of biology, including: discovery of DNA, cancer systems biology, aging and developmental biology. (wikipedia.org)
Our general focus is on stem cell fate choice by epigenetic regulation, transcription regulation via specific developmental transcription factors, and chromatin modifying factors. (ad-astra.ro)
Research focuses on inflammation, tissue repair and developmental biology in the context of asthma, chronic obstructive pulmonary disease, pulmonary hypertension, and congenital diaphragmatic hernia. (umanitoba.ca)
Our work spans the spectrum of cell, developmental, and cancer biology. (bcm.edu)
We study how spatiotemporal cues coordinate the identity and multicellular movement of epithelial cells during morphogenesis within the normal breast, and how developmental signals, often co-opted during cancer progression, direct the invasion and spread of tumor cells to distant organs during breast cancer metastasis. (bcm.edu)

The flagellum is a unique molecular machine driving bacterial movement through liquid environments. (ncl.ac.uk)
Our research focuses on the fundamental understanding of how bacteria regulate flagellar assembly, how a cell coordinates the assembly of unrelated molecular machines and how hosts recognise this important antigen. (ncl.ac.uk)
Nature Structural & Molecular Biology. (montana.edu)
Substrate diffusion is the constant movement of substrate molecules caused by molecular motion. (jove.com)
Although, the non-muscle myosin II holoenzyme (myosin) is a molecular motor that powers contraction of actin cytoskeleton networks, recent studies have questioned the importance of myosin motor activity cell and tissue shape changes. (elifesciences.org)
The Roarty Laboratory investigates the molecular mechanisms regulating the cellular makeup within tumors and how cell populations communicate during breast cancer progression. (bcm.edu)
Our research uses an interdisciplinary approach to study these topics, with diverse methodologies, such as molecular and structural biology, protein chemistry and cell biology. (iit.edu)
This strategy allows us to characterize the behavior of enzymes and understand molecular and subatomic aspects, such as electron movement and conformational changes, and apply these concepts to cell to cell relationships, disease development and drug design. (iit.edu)
The intriguing realm of porifera, known as sponges, beckons exploration in molecular biology. (lu.se)
The dynamic world of porifera, commonly known as sponges, presents a captivating avenue for exploration within molecular biology. (lu.se)

Every cell consists of cytoplasm enclosed within a membrane, and contains many macromolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites. (wikipedia.org)
Diffusion is essentially the movement of molecules from a region of higher concentration to a region of lower concentration as a result of thermal motion. (biologyonline.com)
Specifically, diffusion is the mechanism of movement of oxygen, nutrients and other molecules across the capillary walls and the movement of other molecules across membranes. (biologyonline.com)
There are integral membrane proteins called transporters that mediate movement of molecules that are too polar or too large to move across a membrane by diffusion. (biologyonline.com)
Which of these molecules can NOT pass through a membrane to enter a cell? (com.ng)
Which of these molecules can pass through a cell via active transport? (com.ng)
Inside every cell, billions of molecules continually writhe in an endless, carefully choreographed dance. (cosmosmagazine.com)
Using their new movie camera and tagging technique, the team has already discovered that actin - a protein 'railway' that shuttles cargo around the cell - also helps the cell's membrane fold around and engulf molecules from outside. (cosmosmagazine.com)
In 1974, Hay showed that the extracellular matrix, a collection of structural molecules that surround cells, influences cell behavior. (asu.edu)
To understand how these cells recognise each other as different, I am looking at cell surface signalling molecules called Eph/Ephrins. (cardiff.ac.uk)

Coronavirus disease 2019 emergency and remote eye movement desensitization and reprocessing group therapy with adolescents and young adults: Overcoming lockdown with the butterfly hug. (emdria.org)
Fabian is the director of the Institute of Computational Biology at the Helmholtz Center Munich and scientific director of the Helmholtz Artificial Intelligence Cooperation Unit (HelmholtzAI) which was launched in 2019. (lu.se)

The cell is the basic structural and functional unit of all forms of life. (wikipedia.org)
My laboratory uses, bacterial genetics, protein biochemistry, structural biology, bioinformatics and microscopic techniques to validate our genetic findings. (ncl.ac.uk)
Comparison of the structural and functional specialisations of cells lining the stomach with those of the cells lining the small intestine. (markedbyteachers.com)
Section F, Structural biology communications. (lu.se)

Cell theory, first developed in 1839 by Matthias Jakob Schleiden and Theodor Schwann, states that all organisms are composed of one or more cells, that cells are the fundamental unit of structure and function in all living organisms, and that all cells come from pre-existing cells. (wikipedia.org)
Mathematical and theoretical biology , or biomathematics , is a branch of biology which employs theoretical analysis, mathematical models and abstractions of the living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of experiments to prove and validate the scientific theories. (wikipedia.org)

Journal of Computational Biology. (montana.edu)

Which part of the cell makes the basic amino acid chain for proteins? (com.ng)
Which of the following cell structures assembles proteins using coded instructions that come from the nucleus? (com.ng)
This mouse embryo cell moves around thanks to two proteins - actin (purple) and myosin (green) - dancing in sync. (cosmosmagazine.com)
Actin proteins (red) help this monkey cell create surface pockets (green) by which they can engulf nutrients from outside. (cosmosmagazine.com)
Actin proteins (purple) let this monkey cell form "ruffles" that help the cell crawl along a surface. (cosmosmagazine.com)
Some Example Projects: Regulation of HDM2 and HDMX proteins The HDM2 oncoprotein is the major negative regulator of p53 function in the cell. (southampton.ac.uk)
Role of CtBP transcriptional repressors in cancer cell proliferation and survival In common with p53, CtBP1 and CtBP2 proteins were discovered through their physical association with a viral oncoprotein. (southampton.ac.uk)

They are simpler and smaller than eukaryotic cells, and lack a nucleus, and other membrane-bound organelles. (wikipedia.org)
page needed] A prokaryotic cell has three regions: Enclosing the cell is the cell envelope, generally consisting of a plasma membrane covered by a cell wall which, for some bacteria, may be further covered by a third layer called a capsule. (wikipedia.org)
Though most prokaryotes have both a cell membrane and a cell wall, there are exceptions such as Mycoplasma (bacteria) and Thermoplasma (archaea) which only possess the cell membrane layer. (wikipedia.org)
The separation of charges influences the movement of ions across the membrane. (biologyonline.com)
Lipids cannot pass through the cell membrane because they are too large to fit through. (com.ng)
Dissociation of progeny vaccinia virus from the cell membrane is regulated by a viral envelope glycoprotein: effect of a point mutation in the lectin homology domain of the A34R gene. (microbiologyresearch.org)
In most human cells, mitochondria contain 10 3 -10 4 copies of a circular genome of 16,569 base-pairs that encodes two ribosomal RNAs, 22 tRNAs, and 13 polypeptides that form parts of the respiratory-chain located in the inner mitochondrial membrane [ 9 , 10 ]. (biomedcentral.com)
We investigate immortalized cells in terms of migration, proliferation, stress and membrane conformation on the nanowires. (lu.se)
In order to deepen our understanding of the interactions between the cell membrane and nanostructures, we perform STED microscopy live imaging of the membrane of cells cultured on nanostructures. (lu.se)

I realized that professional swimming didn't really exist and found my way into chemistry and biology. (medscape.com)
He has significant leadership experience from in large interdisciplinary environments combining expertise across electronics, photonics, physics, chemistry, and biology. (lu.se)

In cell biology, wound healing involves the invasion of fibroblasts into the wound space for tissue regeneration 7 . (nature.com)
Hair follicle stem cells reside in their niche in a quiescent state, but become rapidly activated in response to homeostatic and injury signals to regenerate the tissue. (ad-astra.ro)
Overall, our data highlights that myosin activity is required for rapid cell contraction and tissue folding in developing Drosophila embryos. (elifesciences.org)
Cell shape changes and cell movements drive these tissue-scale transformations. (elifesciences.org)
Hay also discovered a phenomenon later called epithelial-mesenchymal transition, a process that occurs during normal embryo and adult development in which epithelial cells, cells that line external and internal surfaces of the body, transform into mesenchymal stem cells , connective tissue cells that are capable of turning into other cell types. (asu.edu)
Normal stem cells are usually maintained within a niche in a tissue that is dependent on local interactions with other cells for its function and fate. (cardiff.ac.uk)
Eph/Ephrins are important for establishing and maintaining tissue boundaries by recognition of adjacent cells. (cardiff.ac.uk)
Fluorescent staining of actin filaments in fixed tissue sections and tissue culture cells preparations.Note: Unlike many actin antibodies, Acti-stain™ 555 phalloidin binds only to F-actin resulting in low background fluorescence. (cytoskeleton.com)
Phalloidin has been labeled with a proprietary red fluorescent dye which allows it to be used to stain actin filaments in tissue cultured cells and tissue sections (1, see Figure 1) and cell-free preparations. (cytoskeleton.com)

We analyzed the organization and function of mitochondrial DNA in a stable human cell line (ECV304, which is also known as T-24) containing mitochondria tagged with the yellow fluorescent protein. (biomedcentral.com)
In living cells, foci have an apparent diffusion constant of 1.1 × 10 -3 μm 2 /s, and mitochondria always split next to a focus to distribute all DNA to one daughter. (biomedcentral.com)
Mitochondria are the centre of energy production in the cell. (biomedcentral.com)
We now examine the organization of mitochondrial genomes in a human cell line that contains mitochondria tagged with the yellow fluorescent protein (YFP). (biomedcentral.com)
The phrase lives of a cell refers to the independent yet interrelated parts of a human cell including mitochondria, centrioles, and basal bodies that once led independent lives. (cdc.gov)

When Chlamydomonas cells are deflagellated by pH shock or mechanical shear the nucleus rapidly moves toward the flagellar basal apparatus at the anterior end of the cell. (rupress.org)
During flagellar regeneration the nucleus returns to a more central position within the cell. (rupress.org)
The nucleus is connected to the flagellar apparatus by a system of fibers, the flagellar roots (rhizoplasts), which undergo a dramatic contraction that coincides with anterior nuclear movement. (rupress.org)
Cells are broadly categorized into two types: eukaryotic cells, which possesses a nucleus, and prokaryotic cells, which lack a nucleus but still has a nucleoid region. (wikipedia.org)
Viruses, for example, hijack this transport machinery to travel to the nucleus of a host cell. (cosmosmagazine.com)
Swiss 3T3 cell with activated Rho, nucleus is stained with Dapi (blue) and F-actin is stained with Acti-stain™ 555 (red F-actin, Cat. (cytoskeleton.com)
The cell nucleus (blue) is indented by the nanowires. (lu.se)

J Cell Biol (1987) 105 (4): 1799-1805. (rupress.org)
J Cell Biol (2007) 178 (2): 185-191. (rupress.org)
J Cell Biol, 193(1), 2011. (ad-astra.ro)
Mol Cell Biol, 30(10), 2010. (ad-astra.ro)
J Cell Biol, 145(7), 1999. (ad-astra.ro)
J. Cell Biol. (uconn.edu)

All organisms have similar cell membranes. (visionlearning.com)
IEV is formed by wrapping of IMV with intracellular membranes, and is an intermediate between IMV and CEV/EEV that enables efficient virus dissemination to the cell surface on microtubules. (microbiologyresearch.org)

The DNA of a prokaryotic cell consists of a single circular chromosome that is in direct contact with the cytoplasm. (wikipedia.org)
The gene product, Wiskott-Aldrich Syndrome Protein (WASp) is a 502 amino acid protein expressed within the cytoplasm of non-erythroid hematopoietic cells. (medscape.com)

Modern, well equipped laboratories provide us with an excellent research environment, and the opportunity to interact with researchers working on related areas of cancer biology. (southampton.ac.uk)

We have also developed interests in other pathways which regulate gene transcription and cancer cell proliferation in response to stress and changes in cell metabolism. (southampton.ac.uk)

Department of Oral Cell Biology, 1192Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands. (bvsalud.org)

During her freshman year, Hay took an anatomy course taught by biology professor Meryl Rose, whom Hay later said influenced her to study biology. (asu.edu)

Prokaryotic cells were the first form of life on Earth, characterized by having vital biological processes including cell signaling. (wikipedia.org)
Which of the following organelles would you expect to find in a prokaryotic cell? (visionlearning.com)
be familiar with the structure and function of both prokaryotic and eukaryotic cells. (edu.au)

My PhD looked at the movement of white blood cells in response to specific homing signals and how the cell cytoskeleton changes shape, giving me a good introduction to signalling and microscopy. (cardiff.ac.uk)
Actin staining is very useful in determining the structure and function of the cytoskeleton in living a nd fixed cells. (cytoskeleton.com)
The actin cytoskeleton is a very dynamic and labile structure in the living cell, but it can be fixed with paraformaldehyde prior to probing or staining for actin structures. (cytoskeleton.com)
[ 3 ] The exact function of WASp is not fully elucidated, but it seems to function as a bridge between signaling and movement of the actin filaments in the cytoskeleton. (medscape.com)

Nuclear movement and flagellar root contraction and extension are not sensitive to inhibitors of protein synthesis (cycloheximide), or drugs that influence either microtubules (colchicine) or actin-based microfilaments (cytochalasin D). Detergent-extracted cell models contract and extend their flagellar roots and move their nuclei in response to alterations of free calcium levels in the medium. (rupress.org)
Cells can acquire specified function and carry out various tasks within the cell such as replication, DNA repair, protein synthesis, and motility. (wikipedia.org)
A particular interest of our work has been how HDM2 and HDMX protein synthesis is controlled in response to cell-signalling pathways in different cell types, and how this affects p53 function in these cells. (southampton.ac.uk)

Some eukaryotic cells (plant cells and fungal cells) also have a cell wall. (wikipedia.org)

Extracellular vaccinia virus formation and cell-to-cell virus transmission are prevented by deletion of the gene encoding the 37,000-Dalton outer envelope protein. (microbiologyresearch.org)
Cell engineering through gene editing is fundamentally a two-step bioprocess. (nature.com)
Cell growth, cell migration , and gene expression are influenced by the interaction between cells and their extracellular matrix. (asu.edu)
Many current and prospective treatments for cancer work by either inhibiting, or re-activating stress response pathways.Our work focuses on the role of regulators of gene transcription in the response of cancer cells to stress. (southampton.ac.uk)
The gene resides on Xp11.22-23, and its expression is limited to cells of non-erythroid hematopoietic lineage. (medscape.com)
Mammalian embryogenesis is a dynamic process involving gene expression and mechanical forces between proliferating cells. (lu.se)
The coupling of gene expression with the mechanics of cell movement is important for formation of both the trophectoderm and endoderm. (lu.se)
Our model, which couples gene expression with mechanics, suggests that differential adhesion between different cell types is a critical determinant in robust endoderm formation. (lu.se)
which suggests that one altered copy of a gene in each cell would be sufficient to cause the condition. (medlineplus.gov)

I'm looking at the early stages of cancer but not directly in relation to cancer stem cells, but the main premise is cell-to-cell communication and the consequences of local cell-cell interactions on the expansion of the cancer cell. (cardiff.ac.uk)
[ 3 ] This ultrastructural component of cellular architecture is involved fundamentally in intracellular and cell substrate interactions and signaling via its role in cell morphology and movement. (medscape.com)
We have developed a computational modeling framework for studying this process, where the combined effects of mechanical and genetic interactions are analyzed within the context of proliferating cells. (lu.se)

Dr. Surat graduated with a Ph.D. in Cell Biology and Mechanobiology from the Tata Institute of Fundamental Research (Mumbai, India) in 2016. (news-medical.net)

Liang P, Rosas-Lemus M, Patel D, Fang X, Tuz K, Juárez O (2017) Dynamic Energy Dependency of Chlamydia trachomatis on Host Cell Metabolism during Different Stages of Intracellular Growth: Possible role of Sodium -based energetics in Chlamydial ATP generation. (iit.edu)
CtBP activity is modified by UV radiation and glycolytic metabolism, suggesting that CtBPs regulate cell survival in response to cellular stress. (southampton.ac.uk)

The production of several different virus particles in the VV replication cycle represents a coordinated strategy to exploit cell biology to promote virus spread and to aid virus evasion of antibody and complement. (microbiologyresearch.org)
In single celled organisms these pathways are generally involved in ensuring the survival and replication of the individual cell. (southampton.ac.uk)
Some DNA differences result from the blunders during the DNA replication necessary for cell division. (cdc.gov)

[1] The field is sometimes called mathematical biology or biomathematics to stress the mathematical side, or theoretical biology to stress the biological side. (wikipedia.org)
[2] Theoretical biology focuses more on the development of theoretical principles for biology while mathematical biology focuses on the use of mathematical tools to study biological systems, even though the two terms are sometimes interchanged. (wikipedia.org)
Mathematical biology aims at the mathematical representation and modeling of biological processes , using techniques and tools of applied mathematics . (wikipedia.org)
He studies the mathematics of collective animal behaviour, social dynamics and mathematical biology. (lu.se)

These researchers have made a sensational finding in cell biology. (uib.no)
Students will have contact with veterinary surgeons and biology researchers providing insight into these sectors. (aber.ac.uk)

Lysosomes are subcellular organelles responsible for the physiologic turnover of cell constituents. (medscape.com)

Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator. (ad-astra.ro)

Electron microscopy gives a much higher resolution showing greatly detailed cell structure. (wikipedia.org)
To investigate the microscopic structures of cells, Hay began using electron microscopes in her research about limb regeneration. (asu.edu)
To this aim, we use STED microscopy, phase holography microscopy, flow cytometry, immunocytochemistry and electron microscopy techniques to investigate the phenotype of a variety of cells cultured on nanowires and nanotubes. (lu.se)

Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity. (cdc.gov)
To our knowledge, this is the first attempt to combine cell-based spatial mechanical simulations with genetic networks to explain mammalian embryogenesis. (lu.se)

1974. Biological handbooks: Biology data book. (cdc.gov)

Moreover, even when high-purity single-cell sorting can be achieved, viability after sorting is often low to moderate, especially for cell types that are particularly sensitive to hydrodynamic stress or low-density culture conditions (e.g., primary cells or pluripotent stem cell lines). (nature.com)
Chad and I have both been principal investigators on the induced pluripotent stem cell (IPSC) grant. (medscape.com)
I fell in love with the idea of human pluripotent stem cells and started surveying the United States and even Europe for who was playing in that area. (medscape.com)

Events EMBL hosted a futuristic infection biology conference, but it offered even more: an opportunity for postdocs to share their work and network towards future research homes. (embl.org)
The PulseNet specimens have no connection other than symbiotic flora, colonization, contamination, or infection by bacteria that at some point years ago were progeny of the same cell. (cdc.gov)

Although cell neighbors exchange a multitude of signals to guide ductal morphogenesis in development or cellular dissemination, transit, and colonization in breast cancer metastasis, the exact identity and mechanistic insight behind these exchanges are unclear. (bcm.edu)
Examples include exposure to toxic compounds or radiation, loss of contact with other cells or the extra-cellular matrix, lack of oxygen (hypoxia), acidic pH, the activation of oncogenes, induction of cellular senescence, oxidative damage or depletion of essential metabolites. (southampton.ac.uk)

Abstract relational biology (ARB) is concerned with the study of general, relational models of complex biological systems, usually abstracting out specific morphological, or anatomical, structures. (wikipedia.org)

Rotation of the filament is achieved via the action of a universal joint known as the hook and a basal motor anchored into the bacterial cell envelope. (ncl.ac.uk)
The work of PulseNet provides insight into the lives of a bacterial cell through DNA pattern matches. (cdc.gov)
All 3 interpretations of lives of a cell the once independent lives of a single cell, the many lives of the earth, and the lives of a bacterial cell that travels throughout the earth strongly suggest a need for multidisciplinary and interdisciplinary collaborations, such as, One Health. (cdc.gov)

When one cell divides into new cells to reproduce. (com.ng)
As each of the cell progeny divides, the new pattern lives on in each new clone. (cdc.gov)

Invasion processes are ubiquitous throughout cell biology and ecology. (nature.com)

Briefly, after electroporation of primary T cells with CXCR4 -targeting Cas9 ribonucleoproteins, single T cells are isolated on a chip and expanded into colonies. (nature.com)
Using this method, single-clone editing efficiencies, including the rate of mono- and bi-allelic indels or precise nucleotide replacements, can be assessed within 10 days from Cas9 ribonucleoprotein introduction in cells. (nature.com)
Even with improved delivery of Cas9, some targeted cells remain unedited. (nature.com)

In other situations the response is cell cycle arrest or programmed cell death (apoptosis), providing a barrier to further tumour development that the tumour may ultimately circumvent through the acquisition of a mutation in one of the genes within the stress-response pathway. (southampton.ac.uk)
Organic solvent-induced proximal tubular cell apoptosis via caspase-9 activation. (cdc.gov)

Purpose of review: The identity and functional roles of stem cell population(s) that contribute to fracture repair remains unclear. (researchgate.net)

Here, we establish a method to enable clonal isolation, selection, and expansion of properly edited cells, using OptoElectroPositioning technology for single-cell manipulation on a nanofluidic device. (nature.com)
That's also relevant for cancer stem cells because ultimately no cell is in isolation. (cardiff.ac.uk)
Inside the body, a cell does not exist in isolation. (news-medical.net)

Anatomy55

Organisms16

Diseases3

Chemicals and Drugs53

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Psychiatry and Psychology11

Phenomena and Processes65

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20192

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20161

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19741

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