Cell behaviour. Medical search. Frequent questions

These signals influence the behaviour of the cytoskeleton within neurons. (kcl.ac.uk)
There are two main types of neurons in the cerebral cortex: excitatory pyramidal cells and inhibitory interneurons. (kcl.ac.uk)
Inhibitory interneurons pace and synchronise the activity of excitatory neurons, thereby orchestrating their behaviour. (kcl.ac.uk)
Results: Our results show that selective expression of mHTT in OXT neurons was associated with the formation of mHTT inclusions and a 26% reduction of OXT-immunopositive neurons as well as increased anxiety-like behaviours compared with uninjected mice. (lu.se)
Conclusions: Our results indicate that mHTT expression can exert cell-autonomous toxic effects on OXT neurons without affecting the non-motor phenotype at early time points in mice. (lu.se)

Following such premises, in this paper we propose a novel approach for modelling hematopoietic stem cells behaviour based on multi-agent systems. (unibo.it)

Another promising application of these advances is investigated by Dr. Holger Erfle and his research group at the BioQuant Centre, namely high throughput screening of cells. (analytica-world.com)
Founded in 2016, the Centre comprises 12 labs whose research feeds into the mission of understanding how the brain generates behaviour. (wikipedia.org)
Vancouver, BC - Transformative technology developed by Vancouver Coastal Health Research Institute (VCHRI) researcher Dr. Mads Daugaard at the Vancouver Prostate Centre (VPC) is putting cell analytics into the hands of scientists around the globe. (vchri.ca)

Neuroscience research spans from molecules, cells and pathways, all the way up to complex human behaviour. (edu.au)
Neuroscience integrates physics, chemistry and biology, with studies of anatomy, physiology and behaviour, including human emotional and cognitive functions. (edu.au)

A ) 2-photon GCaMP imaging combined with behavioural tracking during virtual hunting behaviour (see Materials and methods). (elifesciences.org)
In each case, three representative behavioural events are shown with the value of the regressor and recorded calcium activity from a well modelled cell. (elifesciences.org)
Despite their behavioural differences, both healthy and diseased human tendon cells responded to electrospun PDO fibres. (ox.ac.uk)
Mice underwent a battery of behavioural tests to assess psychiatric and social behaviours 3 months post-injection or at 2 months of age, respectively. (lu.se)

Receptor tyrosine kinases including EGFR, HER-2 and c-Met and non receptor tyrosine kinase including Jaks are selectively expressed in primary tissue and metastatic tumour of advanced ovarian cancer cells. (otago.ac.nz)
centrosome dynamics), and tumour cell fate, behaviour and heterogeneity. (southampton.ac.uk)
Our work will lay the foundation for a more ambitious, collaborative project bringing together expertise in cell and molecular biology, cancer biology, physics, and mathematics, to investigate the causal relationship between ANXA1-mediated defects in cell divisions and tumour heterogeneity, and the underlying mechanisms. (southampton.ac.uk)
Tumour cells are able to recruit macrophages and change their behaviour. (lu.se)

The working group of the Histiocyte Society divided histocytic disorders into three groups: (1) dendritic cell histiocytosis, (2) macrophage-related disorders, and (3) malignant histiocytosis. (medscape.com)
In murine or borderline malignant behaviour. (cdc.gov)

αβ-Double Negative CD4/CD8 (CD56) T cell (DNTs) in metastatic melanoma: basal frequency and behaviour during Ipilimumab treatment. (biomedcentral.com)

Cancer is a complex disease characterised by abnormal gene behaviours and unstable DNA. (cancercouncil.com.au)
The team have focussed on characterising a subset of genes called non-protein coding RNAs, the most diverse class of molecules in cells, which have abnormal activity in cancer. (cancercouncil.com.au)
Learning difficulties and abnormal behaviour are also common. (lu.se)

Flow cytometry revealed decreased expression of CD106, a marker of mesenchymal stem cells, and increased expression of CD10 on healthy versus diseased tendon cells. (ox.ac.uk)

Polarised epithelial cell divisions represent a critical mechanism for correct partitioning of fate determinants and genomic material into the daughter cells during tissue homeostasis and morphogenesis, and their disruption can lead to severe developmental disorders and diseases such as cancer. (southampton.ac.uk)

Yet, the precise mechanisms coordinating cell polarity and correct mitotic spindle dynamics and chromosome segregation fidelity, to ensure proper epithelial integrity and differentiation remain ill defined. (southampton.ac.uk)
The framework will allow to label for up to 10 markers to visualize at the same time ANXA1, centrosomes, chromosomes, cell-cell adhesion molecules, differentiation markers, proliferation, and apoptosis. (southampton.ac.uk)
M, Peterson C. 2018 Haematopoietic stem suggests that during differentiation a stem cell approaches a stable equili- cells: entropic landscapes of differentiation. (lu.se)
Single cells in these populations exhibit different com- stem cell differentiation, Shannon information binations of regulator activity that suggest the presence of multiple theory, entropy configurations of a potential differentiation network as a result of multiple entry points into the committed state. (lu.se)

The "In vivo Brain Circuit Analysis" platform is a research infrastructure devoted to integrating methods and techniques to interrogate neuronal circuits in health and disease using advanced methods for the perturbation and recording of cell activity. (lu.se)

SWC's mission is to understand how neural circuits produce flexible, complex behaviours. (wikipedia.org)
The Inscopix Miniature microscope system allows to image large-scale brain circuit dynamics via in vivo calcium imaging in freely behaving animals to correlate neural activity with behaviour. (lu.se)

The group developed a way to link biological functions to specific RNA molecules by identifying structural patterns in the RNAs that bind to proteins with known functions in the cell. (cancercouncil.com.au)
Anyone who has ever observed biological cells under a microscope knows how unpredictable their behaviour can be. (analytica-world.com)
The group of Ulrich Schwarz aims at describing in mathematical terms the behaviour of biological cells on micropatterned substrates. (analytica-world.com)
This breakthrough brings benefits to a range of medical and biological procedures where cell counting from images is used - for example, to infer a patient's health from their white and red blood cell counts. (ox.ac.uk)
To understand these factors, I am using three dimensional (3D) cell cultures, chicken embryos and a syngeneic mouse model to investigate the biological activity in ovarian cancer. (otago.ac.nz)
Despite wealth information of these tyrosine kinase expressions and activation, little is known about the biological activity of tyrosine kinases in ovarian cancer cells are present in ascitic fluid. (otago.ac.nz)
In recent years, a few studies have started to investigate the biological activity of ascitic fluid,which is believed to influence behavior of ovarian cancer cells. (otago.ac.nz)
Being typically a minor component of the cell membrane, they are of utmost importance for biological functions that rely on lipid-lipid and lipid-protein interactions (Schnaar and Kinoshita 2015 ). (springer.com)

We recently used a proteomic-based screen to identify a novel mitotic complex including the membrane-associated Annexin A1 (ANXA1) protein that interacts with and regulates cortical recruitment of the LGN spindle orientation complex in mitotic mammary epithelial cells. (southampton.ac.uk)
CD47 binding to α2β1 integrin could regulate cyclooxygenase-2 expression and cell migration on collagen I surface in intestinal epithelial cells. (lu.se)

nVue enables imaging of two distinct brain signals to gain deeper insight into how an ensemble of brain signals interacts during free behaviour in a single imaging session. (lu.se)

They'd be able to study how tumor cells migrate: how they look, how they. (yasni.com)

The team's work produced new methods to study RNA molecules through the structures they form in a cell. (cancercouncil.com.au)
Scientists from Heidelberg University have developed a novel mathematical model to explore cellular processes: with the corresponding software , they now are able to simulate how large collections of cells behave on given geometrical structures. (analytica-world.com)
It can also predict how large collections of cells behave on the given geometric structures. (analytica-world.com)
Brent On 4/19/2022 8:36 AM, John Clark wrote: Experiments on how anaesthetics alter the behaviour of tiny structures found in brain cells bolster the controversial idea that quantum effects in the brain might explain consciousness read more: https://www.newscientist.com/article/2316408-quantum-experiments-add-weight-to-a-fringe-theory-of-consciousness/ -- You received this message because you are subscribed to the Google Groups "Everything List" group. (mail-archive.com)
The observations show that the aggregation process in jaundice starts earlier, form compact structures which move faster initially and thus reducing the effective number of cells in the observation volume at all time intervals compared to that of normal suspensions. (iospress.com)

Understanding how embryonic cells biomolecularly restrict their early developmental potential and promote specific cell commitment helps to provide key insights on cancer plasticity and could improve fertilization protocols. (zeiss.com)
Include problems and successes you've had this week, outstanding questions and any 'eureka moments' where things have fallen into place in your practice or understanding of managing behaviour. (futurelearn.com)
Understanding of the thermal behaviour of lithium-ion batteries is essential to reduce the probability of a thermal runaway. (tudelft.nl)

In quick succession, the preimplantational mouse embryo undergoes a series of cellular divisions involving two critical cell fate decisions. (zeiss.com)
To determine which cells are expressing specific cellular markers and how these cells are organized relative to each other requires volumetric imaging of the pre-implantation embryos by confocal microscopy. (zeiss.com)
Even though the exact insight mechanisms of how ascitic fluid exert to ovarian cancer cells is poorly defined, my research suggests that ascitic fluid can increase expression of oncogenic proteins in ovarian cancer cells and reduce the cellular uptake of targeted drugs. (otago.ac.nz)
How this is achieved is a central area of research and has relevance to other examples of cellular migration such as cancer cell metastasis. (kcl.ac.uk)
The analysed data is represented by aggregation parameters-aggregate size index, aggregate sedimentation time index, total number of fluctuations, time required for completion of process, effective number of cells and effective cellular sedimentation duration. (iospress.com)
The term Langerhans cell histiocytosis is generally preferred to the older term, histiocytosis X. This newer name emphasizes the histogenesis of the condition by specifying the type of lesional cell and removes the connotation of the unknown ("X") because its cellular basis has now been clarified. (medscape.com)
Specifically, a variety of other cellular populations have been identified that possess phenotypic characteristics similar to Langerhans cells, including expression of CD207 and Birbeck granules. (medscape.com)
Therefore, in addition to epidermal Langerhans cells, other potential cellular origins for LCH include dermal langerin + dendritic cells, lymphoid tissue-resident langerin + dendritic cells, and monocytes that can be induced by local environmental stimuli to acquire a Langerhans cell phenotype. (medscape.com)

Interactions between cell and matrix mechanics in vivo are of particular importance in a wide variety of disorders, including cancer, central nervous system injury, fibrotic diseases, and myocardial infarction. (scitube.io)

Interactions between cells and materials in vitro can modify cell phenotype and ECM structure, whether intentionally or inadvertently. (scitube.io)

These accounts, it said, were part of a coordinated networks and were removed not based on content or fake news but for "inauthentic behaviour" and for pushing spam. (indiatimes.com)
We're taking down these pages and accounts based on their behaviour, not the content they posted," he said. (indiatimes.com)

Glycosphingolipids (GSLs) are a subclass of glycolipids that are found in cell membranes of various organisms ranging from bacteria to humans. (springer.com)
In the past biennium, working groups have concluded that there is sufficient evidence to classify infection with human immunodeficiency virus (HIV-1), human T-cell lymphotropic virus (HTLV-1), Epstein-Barr virus (EBV) and the Kaposi sarcoma-associated herpesvirus 8 as carcinogenic to humans (IARC 0RQRJUDSKV, Vol. 67 and 70). (who.int)

The study of the hematopoietic system raises some fundamental issues about the regulation mechanisms that control the overall production of terminally differentiated blood cells. (unibo.it)
This week Paul introduced the foundation of behaviour management as your ability to control yourself. (futurelearn.com)
The decision mechanism switches among two behaviours that are previously developed (a pheromone-based swarm control and a sinusoidal rectilinear modular robot movement). (mdpi.com)
We explore how molecular interactions between proteins and small molecules, defined at atomic resolution, govern biochemical output and in turn control cell behaviour. (southampton.ac.uk)
It is responsible for our most sophisticated and diverse behaviours through its control of motor and sensory functions. (kcl.ac.uk)

Specifically, the group aimed to systematically investigate the structure and function of non-coding RNA molecules, which interfere with chromosome organisation in breast cancer cells. (cancercouncil.com.au)
With these molecules in hand, it became possible to investigate the phase behaviour of liquid ordered/liquid disordered supported membranes doped with the Gb 3 species by means of fluorescence and atomic force microscopy. (springer.com)
Such heterogeneity could originate from extrinsic factors, such as cell-to-cell signalling and surrounding temperature and pressure, but also from the intrinsic noise generated by having few copies of molecules involved in transcription and translation. (lu.se)

Cells not only respond to definitively mechanical cues from the extracellular matrix (ECM) but can also sometimes alter the mechanical properties of the matrix and hence influence subsequent matrix-based cues in both physiological and pathological processes. (scitube.io)
Resulted from routine and automated features of decision-making processes, human activity and travel behaviour exhibit a high level of spatial-temporal periodicities as well as a certain order of the activities. (intechopen.com)

The software supports the evaluation of microscope-based observations of cell behaviour on micropatterned substrates. (analytica-world.com)
Scientists can take pictures of cell cultures through any lab microscope using the SnapCyte adapter (shown here). (vchri.ca)
All you have to do is take the plate with the cell culture out of an incubator for a minute and put it under a microscope where you can then snap a picture of it with your smartphone. (vchri.ca)

A new study says immune system cells gather and swarm together to get rid infective pathogens from the body. (themedguru.com)

Some authors [ 4 , 7 , 8 , 10 ] observed that WC-Co alloys typically displayed pseudopassivation behaviour and do not give the active-passive transition one associates with alloys having the ability to undergo passivation when polarised in a corrosive liquid medium. (hindawi.com)
The first model that has been created describes the electric behaviour of a lithium-ion battery cell that is typically implemented in marine applications. (tudelft.nl)
Cell temperatures remain relatively constant after the fourth cell in a row, meaning that modules are typically not limited by the number of cells. (tudelft.nl)

Tendinopathic tissue has a disorganised extracellular matrix, altered vasculature, and infiltration of fibroblasts and inflammatory cells. (ox.ac.uk)

This is especially useful where the cell structure is complex, such as a cell that evolves or adapts, and could help researchers to more fully understand cell behaviour. (ox.ac.uk)
Notably, LCH cells have been found to express markers of both resting epidermal Langerhans cells (CD1a, intracellular major histocompatibility complex II [MHCII], Birbeck granules) and activated Langerhans cells (including CD54 and CD58). (medscape.com)
The programmes governing the function and fate of cells are to a large extent driven by the coordinated activity of transcription factors forming complex and dynamic gene regulatory networks (GRNs). (lu.se)

We compared the response of healthy and diseased human tendon cells to electrospun PDO fibres using live cell imaging, proliferation, flow cytometry, and gene expression studies. (ox.ac.uk)
Describing a freshman seminar titled "How the Tabby Cat Got Her Stripes or The Silence of the Genes":] The big idea we start with is: "How is the genome interpreted, and how are stable decisions that affect gene expression inherited from one cell to the next? (todayinsci.com)
In this context, in the undifferentiated state, the entropy would be large since fewer constraints exist on the gene expression programmes of the cell. (lu.se)
The activities of transcription factors and other genes involved in cell fate decisions can be measured by a number of different gene expression quantification experiments. (lu.se)
Until recently, and due to technical limitations, for a given cell type such experiments had to be done on an ensemble of many cells and, hence, gene expression quantifi- cations represented the average over a given population. (lu.se)

PDO electrospun scaffolds further promoted CD106negCD10pos expression of healthy tendon cells. (ox.ac.uk)

For that purpose, Philipp Albert has developed a complicated computer programme which considers the essential properties of individual cells and their interaction. (analytica-world.com)
The adoption of this paradigm allows to take into account the aspects suggested above, explicitly modelling cell internal behaviour, the environment where they are situated and the interaction between the system entities. (unibo.it)
This interaction enhanced cell migration of CRC cells and TAMs. (lu.se)

You've looked at the impact of adult behaviour and considered what it is like to be taught by you. (futurelearn.com)

Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the presence of cells with characteristics similar to bone marrow-derived Langerhans cells juxtaposed against a backdrop of hematopoietic cells, including T-cells, macrophages, and eosinophils. (medscape.com)
M2 macrophages derived from human monocyte cell line THP-1 secreted high levels of IL-8 and leukotriene D4 (LTD4), which induced colon cancer cell migration, and Th2 cytokines (IL-4, IL-10) to maintain a tumoral immunosuppressive environment. (lu.se)
CD47 is involved in crosstalk between colon cancer cells and macrophages by interacting with its ligand signal-regulatory protein α on macrophages. (lu.se)

We found that disruption of ANXA1 function results in mitotic spindle misorientation and impaired cell-cell adhesion and genome instability, affecting the outcomes of cell division. (southampton.ac.uk)

On the other hand, the infiltration of organs by a monoclonal population of aberrant cells, the possibility of lethal evolution, and the cancer-based modalities of successful treatment are all consistent with a neoplastic process. (medscape.com)

When comparing multiple drug candidates, SnapCyte can very accurately and quickly assess how each drug acts on cancer or other cells to identify the most effective treatment. (vchri.ca)

Arguments supporting the reactive nature of LCH include the occurrence of spontaneous remissions, the extensive elaboration of multiple cytokines by dendritic cells and T-cells (the so-called cytokine storm) in LCH lesions, and the good survival rate in patients without organ dysfunction. (medscape.com)

Calcium indicators, can be recorded at a single cell resolution in freely behaving animals. (lu.se)

Unlike current technology that uses duplicate samples of a cell culture with a medium/serum solution, SnapCyte can be used on experiments in the plates where the cell culture is grown. (vchri.ca)

Research Fellow Weidi Xie, together with Professors Alison Noble and Andrew Zisserman, has won the Taylor and Francis Best Paper Award for his DPhil research into microscopy cell counting and detection. (ox.ac.uk)
The use of these two behaviours is a popular subject in robotics research involving search, rescue and exploration. (mdpi.com)
The main objective of this research is therefore to investigate the implications on preliminary submarine system design based on the thermal behaviour of lithium-ion batteries and to quantify the thermal behaviour and design implications. (tudelft.nl)
The artificial intelligence (AI)-driven smartphone app SnapCyte produces data used in cell growth medical research at a fraction of the cost and in a more timely manner than current technology. (vchri.ca)
Dr. Mads Daugaard is an associate professor with the Department of Urologic Sciences at the University of British Columbia and a senior research scientist and head of the Molecular Pathology and Cell Imaging Unit with the VPC. (vchri.ca)
SnapCyte's cloud-based platform allows users to not only accurately measure their collective cell culture data in minutes - the big data it gathers could also provide important insights to further advance scientific research. (vchri.ca)

This discovery supports the idea that the synapses made by excitatory pyramidal cells and the parvalbumin-positive interneurons might be particularly sensitive to dysregulation seen in developmental brain conditions such as ASD. (kcl.ac.uk)

While the people behind this activity attempted to conceal their identities, our review found that it was connected to individuals associated with an INC IT Cell," Gleicher said. (indiatimes.com)
The experimental results demonstrate the potential to annotate call locations based on the integration between machine learning algorithms and the characteristics of underlying activity and travel behaviour, contributing towards the semantic interpretation and application of the massive data. (intechopen.com)

In the human body, microbial cells. (scitube.io)
Resorbable electrospun polydioxanone fibres modify the behaviour of cells from both healthy and diseased human tendons. (ox.ac.uk)

Used in the analysis of cancer cells and other diseases at a microscopic scale, the first-of-its-kind SnapCyte app could supercharge the development of novel, personalized medical treatments, says Daugaard. (vchri.ca)

Electrospun fibres increased the proliferation rate of diseased tendon cells and increased the ratio of type I:IIIcollagenmRNA expression. (ox.ac.uk)

Does chronic negativity really kill brain cells? (acel.org.au)

Cell 169 , 203-215 (2017). (nature.com)
In November 2017, a new device called Neuropixels was announced that records from hundreds of brain cells simultaneously. (wikipedia.org)

Examination of cells whether from a primary or secondary site, including fluids aspirated using endoscopes or needles. (who.int)

Although the epidermal Langerhans cell has been presumed to be the cell of origin in LCH, recent studies have called this belief into question. (medscape.com)

Severe defects, with absent T cells, should be considered for BMT. (lu.se)

The substrate for microscopic study is structured in such a way that it normalises cell behaviour. (analytica-world.com)

The findings of his paper, 'Microscopy Cell Counting and Detection with Fully Convolutional Regression Networks' could mean that the current time-consuming method of manually counting cells becomes a thing of the past, and that previously unattainable data from overlapping or clumped cells is now made available. (ox.ac.uk)
Our preliminary data suggested a lower frequency of αβ-DNTs and a worse immunological impairment in MM compared to healthy and lymphoma subject as well as a trend of increasing of this T-cell population during the therapy. (biomedcentral.com)
Cell phone call location data has been utilized for the study of travel patterns, but the underlying activities that originate the movement are still at a less explored stage. (intechopen.com)
The affordable smartphone platform delivers real-time cell behaviour data to enhance precision medicine. (vchri.ca)
It also collects and displays cumulative cell data in growth curves to aid with monitoring cell development over time, which can be easily shared among researchers. (vchri.ca)

Wrinkling of cell nuclei is associated with disease. (nature.com)
[ 3 ] Taken together, these findings have led some to speculate that LCH is not a specific disease of epidermal Langerhans cells, but rather one of mononuclear phagocyte dysregulation. (medscape.com)

Anatomy39

Organisms10

Diseases5

Chemicals and Drugs37

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

Psychiatry and Psychology64

Phenomena and Processes54

Disciplines and Occupations2

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20172

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