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  • human
  • Viscoelasticity is a property of human blood that is primarily due to the elastic energy that is stored in the deformation of red blood cells as the heart pumps the blood through the body. (wikipedia.org)
  • tumor cells
  • In mouse intraperitoneal xenograft models of EOC, inhibition of P-cadherin decreased the aggregation and survival of floating tumor cells in ascites and reduced the number of tumor implants on peritoneal surfaces. (aacrjournals.org)
  • The most widely recognized pattern of EOC dissemination is intraperitoneal "seeding" in which tumor cells passively shed into, and are transported by, the circulating peritoneal fluid ( 2-4 ). (aacrjournals.org)
  • It is thought that aggregation of floating EOC cells prevents anoikis and also facilitates the implantation of tumor cells on to peritoneal surfaces such as the cavity wall, bowel serosa, and the omentum ( 3-5 ). (aacrjournals.org)
  • Cryptotanshinone inhibited TCIPA and MMP-2 release from platelets and tumor cells. (aacrjournals.org)
  • Prolonged culture resulted in a 10-fold decrease in the incidence of B16a lung colonies, whereas passage in vivo for 150 days did not affect lung colony formation by tumor cells isolated from enzymatic dispersates by centrifugal elutriation. (rti.org)
  • Over-confluent tumor cells produced even lower number of lung colonies. (rti.org)
  • interaction
  • Interestingly, AIDA-expressing cells can interact with antigen 43 (Ag43) -expressing cells, which is indicative of an intercellular AIDA-Ag43 interaction. (forskningsdatabasen.dk)
  • The wide variety of effects of galectin-3 on cancerous cells are due to the unique structure and various interaction properties of the molecule. (wikipedia.org)
  • The many interaction and binding properties of galectin-3 influence various cell activities based on its location. (wikipedia.org)
  • This galectin is strongly overexpressed in Hodgkin's disease tissue and it might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its consistently associated immunodeficiency. (wikipedia.org)
  • The expression of CD97 on macrophage and the abundant presence of its ligand CD55 on fibroblast-like synovial cells suggest that the CD97-CD55 interaction is involved in the recruitment and/or retention of macrophages into the synovial tissue in rheumatoid arthritis. (wikipedia.org)
  • intercellular
  • In addition to inhibiting neoplastic cell adhesion to the endothelium and homotypic aggregation, disrupting this line of intercellular communication using synthetic Thomsen-Friedenreich antigen masking and Thomsen-Friedenreich antigen mimicking compounds greatly affects cancer cell clonogenic survival and growth as well. (aacrjournals.org)
  • Basophils and mast cells that are treated with CCL2 release their granules to the intercellular space. (wikipedia.org)
  • ligands
  • Inhibition studies show that the ligands responsible for this aggregation are CD11c/CD18 and ICAM-1, both of which are expressed on BJ/873. (cshl.edu)
  • endothelium
  • Additionally, LD/LP cells demonstrated higher adhesion to endothelium than HD/HP B16a cells. (rti.org)
  • In addition, CD97 promotes angiogenesis of the endothelium through to α5β1 and αvβ3 integrins, which contributes to cell attachment. (wikipedia.org)
  • significantly
  • 1 , 4 For example, increased RBC aggregation, elevated blood viscosity and the ratio of hematocrit (Hct) to blood viscosity (HVR, an index to the oxygen transport potential of blood) have been shown to significantly affect in vivo microcirculatory flow dynamics. (haematologica.org)
  • Using a SCA3 ATXN3/Q75-GFP cell model, we found that the ATXN3/Q75 aggregation was significantly prohibited by lactulose and melibiose because of their abilities to up-regulate autophagy. (eurekaselect.com)
  • Results:MCF-7 cells released significantly more MMP-2 than MDA-MB-231 cells and were more efficacious in inducing TCIPA. (aacrjournals.org)
  • Cultured B16a cells maintained at low density (LD) and harvested at low passage (LP) formed significantly more lung colonies than B16a cells harvested at high densities (HD) or high passage (HP). (rti.org)
  • ligand
  • Other responses include: respiratory burst, production of arachidonic acid metabolites, dendritic cell maturation, and phagocytosis of the ligand. (wikipedia.org)
  • inhibition
  • The suppression of cell-aggregation activity indicates the potential of these compounds in the treatment of Gram-positive bacterial infections via the inhibition of SrtA. (omicsonline.org)
  • Inhibition of MMP-2 with phenanthroline (1-1000 mM), a synthetic inhibitor of MMPs, and by neutralizing anti-MMP-2 antibody (10 mg/ml) reduced TCIPA induced by MCF-7 cells. (aacrjournals.org)
  • We first investigated the effects of cell source and culture conditions on lung colony formation by i.v. injected B16a (B16 amelanotic melanoma) cells and inhibition of tumor colony formation by the thromboxane A2 synthase inhibitor, CGS14854. (rti.org)
  • Lung colony formation by elutriated B16a cells (i.e., cells freshly isolated from tumor tissue) was consistently inhibited by CGS14854, whereas inhibition of lung colony formation by cultured B16a cells was dependent upon culture conditions. (rti.org)
  • The inhibition of Gas6 activity by soluble Mer led to defective macrophage-mediated engulfment of apoptotic cells. (bloodjournal.org)
  • Tissue
  • These surfaces are lined by a monolayer of mesothelial cells that acts as a protective barrier against tissue injury and infection ( 6 ). (aacrjournals.org)
  • Our new special issue is packed with articles that use mathematical and physical approaches to gain insights into cell and tissue patterning, morphogenesis and dynamics, and that provide a physical framework to capture these processes operating across scales. (biologists.org)
  • In plant chimeras, however, the distinct types of tissue may originate from the same zygote, and the difference is often due to mutation during ordinary cell division. (wikipedia.org)
  • differential
  • The differences in lung colony formation between LD, HD and elutriated B16a cells were not due to differential cell-cycle distribution. (rti.org)
  • metastatic
  • The two major theories of cancer metastasis, the seed and soil hypothesis and the mechanical trapping theory, view tumor cell adhesion to blood vessel endothelia and cancer cell aggregation as corresponding key components of the metastatic process. (aacrjournals.org)
  • The present study was undertaken to investigate the factors involved in determining the metastatic potential of cultured cells derived from solid tumors. (rti.org)
  • expression
  • Cells were harvested and the expression of THAP11 were detected by Western Blotting analysis using anti-THAP11 antibody. (wiley.com)
  • 16 Mer is also ectopically expressed in pediatric T-cell acute lymphoblastic leukemia, 17 and a Mer transgenic mouse model with ectopic expression of Mer in thymocytes and lymphocytes develops T-cell lymphoblastic leukemia/lymphoma. (bloodjournal.org)
  • CCL2 expression in glial cells is increased in epilepsy, brain ischemia Alzheimer's disease experimental autoimmune encephalomyelitis (EAE), and traumatic brain injury. (wikipedia.org)
  • This SNP would result in less REST repressor activity, which could lead to increased expression of PTPrho (PTPRT) in cells that harbored this SNP. (wikipedia.org)
  • Expression has also been studied on other immune cells including eosinophils and B cells. (wikipedia.org)
  • Most research utilizes mice models, but heterologous expression systems are utilized as well, including, but not limited to, Madin-Darby canine kidney cells and COS-7 Cells. (wikipedia.org)
  • Ectopic CD97 expression upregulates the expression of N-cadherin and β-catenin in HT1080 fibrosarcoma cells leading to enhanced cell-cell aggregation. (wikipedia.org)