• ceftazidime sodium cefuroxime sodium celestone cena k cephalexin cephalothin sodium cephapirin sodium cephradine cephradine dihydrate cephulac ceptaz cerubidine cetacort cetamide chemdec dm chemdec chlor-trimeton chloral hydrate chloramphenicol chloramphenicol sodium succinate chlordiazachel chlordiazepoxide hydrochloride chlorofair chlorhexidine gluconate chloromycetin chloroprocaine hydrochloride chloroptic chloroptic s. (cleaningmygun.com)
  • The generic version of cefoxitin is known as cefoxitin sodium. (wikipedia.org)
  • MEFOXIN contains approximately 53.8 mg (2.3 milliequivalents) of sodium per gram of cefoxitin activity. (rxlist.com)
  • Each conventional vial contains sterile cefoxitin sodium, USP equivalent to 1 g, 2 g or 10 g cefoxitin. (rxlist.com)
  • Cefoxitin Sodium, USP is the sodium salt of Cefoxitin, a cephamycin β-lactam second-generation cephalosporin that is resistant to β-lactamases. (toku-e.com)
  • Cefoxitin Sodium is freely soluble in aqueous solution. (toku-e.com)
  • Cefoxitin sodium is a 2nd generation cephalosporin that is FDA approved for the treatment of lower respiratory tract infections , urinary tract infection , gynecological infections , septicemia , bone and joint infections , and skin infections . (wikidoc.org)
  • Cefoxitin requires a prescription and as of 2010 is sold under the brand name Mefoxin by Bioniche Pharma, LLC. (wikipedia.org)
  • Mefoxin (cefoxitin) is a cephalosporin antibiotic used to treat many kinds of bacterial infections, including severe or life-threatening forms. (rxlist.com)
  • Our Mefoxin (cefoxitin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • MEFOXIN (cefoxitin for injection) is a semi-synthetic, broad-spectrum cepha antibiotic sealed under nitrogen for intravenous administration. (rxlist.com)
  • For the purposes of detecting bacterial strains with the mecC gene, which like mecA codes for a different PBP, cefoxitin is more reliable than oxacillin because mecC does not correlate as strongly with oxacillin resistance. (wikipedia.org)
  • This PBP has a lower binding affinity for penicillin-based antibiotics such as cefoxitin and will continue to cross-link the peptidoglycan layers of the cell wall even in the presence of the beta-lactam antibiotics. (wikipedia.org)
  • Cefoxitin may interact with antibiotics. (rxlist.com)
  • Cefoxitin is a second-generation cephamycin antibiotic developed by Merck & Co., Inc. from Cephamycin C in the year following its discovery, 1972. (wikipedia.org)
  • Cefoxitin is a beta-lactam antibiotic which binds to penicillin binding proteins, or transpeptidases. (wikipedia.org)
  • Due, in part, to the unavailability of methicillin in the United States, cefoxitin has replaced methicillin for disk diffusion tests, which determine the sensitivity of a bacterial specimen to a given antibiotic. (wikipedia.org)
  • Cefoxitin is a broad-spectrum antibiotic effective against several Gram-positive and Gram-negative bacteria. (toku-e.com)
  • Cefoxitin, and the cephamycin family as a whole, served as a branching point and impulsed the discovery of more classes of beta-lactams. (wikipedia.org)
  • Cefoxitin was discovered in 1972 and developed by Merck & Co. and Lilly from Cephamycin C. It was synthesized in order to broaden its spectrum. (toku-e.com)
  • Cephaloridine versus cephalothin: relation of the kidney to blood level differences after parenteral administration. (webmd.com)
  • Yet only cefoxitin retained its previous effectiveness against Gram negative bacteria, developed effectiveness against Gram positive bacteria, and resisted breakdown by beta-lactamase. (wikipedia.org)
  • The usual adult dosage range of cefoxitin is 1 gram to 2 grams every six to eight hours. (rxlist.com)
  • Therefore, when Cefoxitin for injection, USP is used in the treatment of patients with pelvic inflammatory disease and C. trachomatis is one of the suspected pathogens, appropriate anti-chlamydial coverage should be added. (wikidoc.org)
  • Cefoxitin for injection, USP has a high degree of stability in the presence of bacterial beta-lactamases, both penicillinases and cephalosporinases. (wikidoc.org)
  • Cefoxitin for injection, USP is indicated for the prophylaxis of infection in patients undergoing uncontaminated gastrointestinal surgery, vaginal hysterectomy, abdominal hysterectomy, or cesarean section. (wikidoc.org)
  • The scientists used chemically modified the compound to give cefoxitin, so titled due to its semi-synthetic nature. (wikipedia.org)
  • Cefoxitin also yields more accurate results for disk diffusion tests. (wikipedia.org)
  • Yet only cefoxitin retained its previous effectiveness against Gram negative bacteria, developed effectiveness against Gram positive bacteria, and resisted breakdown by beta-lactamase. (wikipedia.org)
  • Resistance to cefoxitin is primarily through hydrolysis by beta-lactamase, alteration of penicillin-binding proteins (PBPs), and decreased permeability. (nih.gov)
  • By binding to PBPs, cefoxitin prevents the PBPs from forming the cross-linkages between the peptidoglycan layers that make up the bacterial cell wall, thereby interfering with cell wall synthesis. (wikipedia.org)
  • As a cephamycin, cefoxitin is highly resistant to hydrolysis by some beta-lactamases, in part due to the presence of the 7-alpha-methoxy functional group (see skeletal formula above). (wikipedia.org)
  • Cefoxitin is a beta-lactam antibiotic which binds to penicillin binding proteins, or transpeptidases. (wikipedia.org)
  • This PBP has a lower binding affinity for penicillin-based antibiotics such as cefoxitin and will continue to cross-link the peptidoglycan layers of the cell wall even in the presence of the beta-lactam antibiotics. (wikipedia.org)
  • However, the efficacy of cefoxitin in treating clinical infections due to these microorganisms has not been established in adequate and well-controlled clinical trials. (nih.gov)
  • Approximately 85 percent of cefoxitin is excreted unchanged by the kidneys over a 6-hour period, resulting in high urinary concentrations. (nih.gov)