• The second-generation cephalosporins (cefamandole, cefaclor, cefotetan, cefoxitin, and cefuroxime) have an extended antibacterial spectrum that includes greater activity against additional species of gram-negative rods. (britannica.com)
  • Cefaclor and cefamandole as alternatives to spectinomycin in the treatment of men with uncomplicated gonorrhoea. (bmj.com)
  • cefuroxime and cefamandole) and third-generation ones (such as ceftazidime) tend to be more effective against gram-negative bacterial species that are resistant to the first-generation cephalosporins. (britannica.com)
  • Common choices include ceftriaxone or other third-generation cephalosporins, cefuroxime, and cefamandole. (medscape.com)
  • The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally. (wikipedia.org)
  • The chemical structure of cefamandole, like that of several other cephalosporins, contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain. (wikipedia.org)
  • Cefoperazone, similar to other cephalosporins such as cefamandole, contains the methyltiotetrazole (NMTT) side chain, which can cause hypoprothrombinaemia and consequently bleeding manifestations. (manipal.edu)
  • Cefamandole under brand name mandol is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms such as: lower respiratory infections, including pneumonia, caused by S. pneumoniae. (ncats.io)
  • Cefazolin Ceforanide "Cefamandole sodium salt Susceptibility and 0.5 - 32 Minimum Inhibitory Concentration (MIC) Data" (PDF). (wikipedia.org)
  • Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic. (wikipedia.org)
  • The following drugs or solutions are reportedly incompatible or only compatible in spe-cific situations with tobramycin: cefamandole naftate, furosemide and heparin sodium. (elephantcare.org)
  • The following represents cefamandole MIC susceptibility data for a few medically significant microorganisms. (wikipedia.org)
  • 2023. https://anesth.unboundmedicine.com/anesthesia/view/Davis-Drug-Guide/109106/all/cefamandole. (unboundmedicine.com)
  • Escherichia coli: 0.12 - 400 μg/ml Haemophilus influenzae: 0.06 - >16 μg/ml Staphylococcus aureus: 0.1 - 12.5 μg/ml CO2 is generated during the normal constitution of cefamandole and ceftazidime, potentially resulting in an explosive-like reaction in syringes. (wikipedia.org)
  • cefamandole resistance transfer in bacterial strains from two newborn units. (liverpool.ac.uk)
  • transfer of cefamandole resistance was demonstrated from strains of citrobacter freundii as well as from individual strains of enterobacter cloacae, acinetobacter anitratus and klebsiella pneumoniae isolated from patients in two newborn units. (liverpool.ac.uk)
  • in citrobacter freundii, cefamandole resistance was transferred always with cephalotin resistance as well as with a tem-like beta lactamase (conferring resistance to ampicillin, carbenicillin and azlocillin). (liverpool.ac.uk)
  • Cefamandole is no longer available in the United States. (wikipedia.org)
  • Cefamandole is no longer available in USA, but it has prescription in UK. (ncats.io)
  • En el año 2006 ha sido indexada en la base de datos de Medline, y se ha convertido en uno de los vehículos de expresión de la medicina española más actuales y modernos. (actasdermo.org)
  • While Klebsiella strains donated cefotaxime, cefamandole and cefuroxime resistance to Escherichia coli K-12 recipients, the genetic analysis of exconjugants after the transfer of plasmids from Serratia strains to Proteus or Salmonella recipients showed that the cefoxitin resistance determinant was also co-transferred. (nih.gov)
  • Eosinophilia has been reported to be associated with intravenous administration of tobramycin, including a patient treated for Gram-negative bacteremia [ 8 ], and among nine of 88 patients who received tobramycin in combination with cefamandole for peritonitis [ 9 ]. (biomedcentral.com)
  • Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic. (wikipedia.org)
  • Cefazolin Ceforanide "Cefamandole sodium salt Susceptibility and 0.5 - 32 Minimum Inhibitory Concentration (MIC) Data" (PDF). (wikipedia.org)
  • Cefamandole sodium salt is freely soluble in aqueous solution. (goldbio.com)
  • Cefamandole has a broad spectrum of activity and can be used to treat bacterial infections of the skin, bones and joints, urinary tract, and lower respiratory tract. (wikipedia.org)
  • The following represents cefamandole MIC susceptibility data for a few medically significant microorganisms. (wikipedia.org)