The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. (wikidoc.org)
B-lymphocyte antigen CD20 or CD20 is an activated- glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase ( CD45 R+, CD117 +) and progressively increasing in concentration until maturity. (wikidoc.org)
Description: CD54, also known as Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. (csb-bioenergetics.nl)
In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1). (csb-bioenergetics.nl)
Macrophage3
Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2). (wikipedia.org)
Macrophage-1 antigen (hereafter complement receptor 3 or CR3) (CD11b/CD18) is a human cell surface receptor found on B and T lymphocytes, polymorphonuclear leukocytes (mostly neutrophils), NK cells, and mononuclear phagocytes like macrophages. (wikipedia.org)
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. (wikidoc.org)
Humans1
First, humans are generally tolerant to their own antigens. (coek.info)
Antibody2
Antibody FMC7 ( F linder M edical C entre) appears to recognise a conformational variant of CD20 [10] [11] also known as the FMC7 antigen. (wikidoc.org)
Description: Anti-CD123 IgG antibody is a purified recombinant antibody which recognizes CD123 antigen. (diastrip.com)
Integrin1
Notably, transfection of the subjects' lymphocytes with KINDLIN3 complementary DNA but not CALDAGGEF1 cDNA reverses the LAD-III defect, restoring integrin-mediated adhesion and migration. (ox.ac.uk)
Protein1
The protein has no known natural ligand [4] and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. (wikidoc.org)
Human2
However, it has been difficult to obtain human mAbs, especially those directed at human antigens, for at least two reasons. (coek.info)
R&D Systems Human PDGF R beta (AAA36427) VersaClone cDNA clone contains the complete ORF for PDGF R beta, along with a Kozak consensus sequence for optimal translation initiation. (labome.cn)
Receptor1
It is expressed on erythrocytes and erythroblasts, and serves as a receptor for LFA-1, Mac-1, and CD11c/CD18, plus alpha 4 beta 1 and alpha-V containing integrins. (rndsystems.com)
Cells1
Tumor immunogenicity results from the processing, and subsequent presentation of tumor antigens released from dead or dying tumor cells on MHC molecules expressed on antigen-presenting cells (APC). (aacrjournals.org)
Carcinoembryonic antigen family1
Members of the carcinoembryonic antigen family (CEACAMs) are widely expressed, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. (biomedcentral.com)
Immunocompetent cells3
The blood-testis barrier and the epididymal blood-epithelium barrier in humans are important structures in preventing sperm antigens from contacting immunocompetent cells, due to the tight junctions of Sertoli and epithelial cells. (medscape.com)
When these antigens come into contact with immunocompetent cells, or spermatozoal antigens are exposed to the mucosal and systemic immune systems, ASA formation occurs. (medscape.com)
They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. (lookformedical.com)
CD11a2
We cloned the cDNA for DS CD11a, the alpha subunit of LFA-1, and co-transfected it along with the previously cloned cDNA for DS CD18, into a Lkt-non-suceptible cell line. (usda.gov)
Pre-incubation of Lkt with a Lkt-neutralizing monoclonal antibody (MAb), or pre-incubation of transfectants with MAbs specific for DS CD11a or CD18, inhibited Lkt-induced cytolysis of the transfectants. (usda.gov)
MAbs1
This increase in neutrophil adhesion caused by CD66 antibodies is blocked by CD18 mAbs and is associated with upregulation of CD11/CD18 on the neutrophil surface. (biomedcentral.com)
Haemolytica leukotoxin1
Deshpande M.S., Ambagala T.C., Ambagala A.P., Kehrli M.E. Jr., Srikumaran S., Bovine CD18 is necessary and sufficient to mediate Mannheimia (Pasteurella) haemolytica leukotoxin-induced cytolysis, Infect. (vetres.org)
Complement1
1 In recent years, it has become increasingly evident that complement is also involved in the antigen-specific immune responses with an identified role in antigen processing and presentation, T-cell proliferation and differentiation, B-cell activation, 2 3 and systemic tolerance induced by the introduction of antigen into an immune-privileged site such as the anterior chamber of the eye. (arvojournals.org)
Immune4
In men, at puberty when the sperm first appear in the testis and epididymis, the human immune system will have the chance to contact sperm antigens. (medscape.com)
Similarly, when women become sexually active, their immune system will inevitably contact sperm antigens. (medscape.com)
Developmental abnormalities of the formation of the blood-testis barrier, traumatic disruption, infection or unilateral focal cryptic obstructions could lead to immunogenic sperm antigens being exposed to the immune system thus initiating an immune response to produce ASAs. (medscape.com)
These strategies include eliminating tumor bulk to provoke the release of tumor antigens, using adjuvants to enhance antigen-presenting cell function, and employ agents that enhance immune cell effector activity. (frontiersin.org)
Cell2
Some of these findings were recapitulated in humans and used to develop cancer immunotherapies based on provoking tumor-antigen-specific T-cell responses ( 4 , 5 ). (frontiersin.org)
Carcinoembryonic antigen-related cell adhesion molecule 8 ( CEACAM8 ) also known as CD66b ( C luster of D ifferentiation 66b ), is a member of the carcinoembryonic antigen (CEA) gene family. (wikidoc.org)
Chains1
The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). (lookformedical.com)
Specific2
The carcinoembryonic antigen (CEA) 2 family consists of two subfamilies, the CEACAM subgroup and the pregnancy specific glycoprotein (PSG) subgroup. (biomedcentral.com)
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. (lookformedical.com)
Important1
The directed expression of SV40 T antigen has led to the development of several important transgenic models with spontaneous epithelial tumor formation. (molvis.org)
Component1
[ 42 ] Among the cross-reactive antigens, the urease complex component UreG of U. urealyticum was determined. (medscape.com)