AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation Science
Antigens, CD8Antigens, CD3CD40 LigandAntigens, CD40Antigens, CD44Antigens, CD34Antigens, CD28CD4-CD8 RatioAntigens, CD14Antigens, CD38CD4-Positive T-LymphocytesAntigens, CD1Antigens, CD80Antigens, CD2Antigens, CD19Antigens, CD86Antigens, CD95Antigens, CD5Antigens, CDAntigens, CD18Antigens, CD56Antigens, CD30Antigens, CD24Antigens, CD36Antigens, CD9Antigens, CD20Antigens, CD7Antigens, CD43CD8-Positive T-LymphocytesAntigens, CD11Antigens, CD47Antigens, CD59Antigens, CD70Antigens, CD46Antigens, CD11bCD4 Lymphocyte CountAntigens, CD57Antigens, CD81Antigens, CD137CD30 LigandAntigens, CD31Antigens, CD11cAntigens, CD151Antigens, CD55Antigens, CD58Antigens, CD63Antigens, CD13Antigens, CD11aAntigens, CD147ImmunophenotypingAntigens, CD82Antigens, CD274Antigens, CD146Immunologic MemoryDendritic CellsFlow CytometryAntigens, Differentiation, T-LymphocyteAntigens, CD15Antigens, CD79T-Lymphocytes, RegulatoryAntigens, CD98Receptors, Antigen, T-CellAntigens, CD164Antigens, DifferentiationMice, TransgenicAntigens, CD53B-LymphocytesAntigens, CD29CytokinesInterleukin-2 Receptor alpha SubunitThymus GlandInterleukin-2Lymphocyte CountCell SeparationSpleenReceptors, Interleukin-2Cytotoxicity, ImmunologicEpitopes, T-LymphocyteHIV-1Killer Cells, NaturalAdoptive TransferT-LymphocytesMolecular Sequence DataForkhead Transcription FactorsHIV InfectionsHematopoietic Stem CellsCell ProliferationLymphocyte SubsetsAntigens, Differentiation, MyelomonocyticT-Lymphocytes, CytotoxicAntigen PresentationReceptors, Antigen, T-Cell, alpha-betaCell LineADP-ribosyl CyclaseMonocytesCoculture TechniquesClone CellsAntigen-Presenting CellsLectins, C-TypeInterleukin-4
Activated plateletsPlatelet activationCD62ECD61Measured by flow cytometryIntegrinExpressionPercentagePositive
Activated platelets1
  • The RB40.34 monoclonal antibody specifically binds to mouse P-selectin (CD62P), a 140 kDa protein which is expressed on activated platelets, activated endothelial cells, and megakaryocytes. (bdbiosciences.com)
Platelet activation3
  • P-selectin (CD62P) is a well-established and commonly used marker for measuring platelet activation. (plateletservices.com)
  • Platelet activation was detected using fluorescent-labeled monoclonal antibodies recognizing the fibrinogen binding conformation of GPIIb-IIIa (referred to herein as PAC-1 binding) and the activation-dependent platelet epitope CD62P (P-selectin). (marscocoascience.com)
  • We observed that PEF application to expired PC induces platelet activation (CD62P positive platelets) and leads to a controlled release of growth factors from the platelets. (inscreva-se.net)
CD62E1
  • Our range of CD62 antibodies (including CD62E (E-Selectin), CD62L (L-Selectin) and CD62P (P-Selectin)) come in a variety of formats and to a wide range of target species. (bio-rad-antibodies.com)
CD611
  • Percentage of platelets positive for CD61 and CD62P remained stable during storage. (biomedcentral.com)
Measured by flow cytometry1
  • CD62P expression in PCs was measured by flow cytometry method, and the CCI of the patients was calculated based on the CCI formula. (phcogj.com)
Integrin1
  • The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand. (ucdavis.edu)
Expression12
  • The study results showed that SARS-CoV-2 induced a fast and substantial rise in the proportion of CD62P platelets and increased the intensity of αIIbβ3* expression. (news-medical.net)
  • however, this concentration level sufficiently induced the surface-level expression of αIIbβ3* and CD62P platelets. (news-medical.net)
  • Stored RBC supernatants and 8-iso-PGF2α induced PLT activation marker CD62P (P-selectin) expression and prothrombotic thromboxane A2 release. (nih.gov)
  • This study aims to determine the difference between the CD62P expression of nonleucodepleted and leucodepleted PCs and to determine the difference between the Corrected Count Increment (CCI) of patients transfused with nonleucodepleted and leucodepleted PCs. (phcogj.com)
  • The median CD62P expression of the nonleucodepleted and leucodepleted groups were 34.4% (16.8-94.4%) and 21.7% (6.2-34.0%), respectively. (phcogj.com)
  • There was a statistically significant difference between the CD62P expression of the two groups (p = 0.00). (phcogj.com)
  • It can be concluded that the CD62P expression in the PCs of the leucodepleted group was significantly lower than those of the nonleucodepleted group and that there was no significant difference between the CCI of both groups. (phcogj.com)
  • CD62P expression plot using flow cytometry method. (phcogj.com)
  • Changes of soluble CD40 ligand in the progression of acute myocardial infarction associate to endothelial nitric oxide synthase polymorphisms and vascular endothelial growth factor but not to platelet CD62P expression. (cdc.gov)
  • To investigate thrombocyte and erythrocyte CD35, CD4 4 and CD62P expression discrepancy and its biological significance of tumor metastasis. (linguix.com)
  • Bioreactor-derived PLPs exhibit functional activity, as evidenced by CD41a and CD42b surface marker expression, CD62P translocation from granules to the surface in response to thrombin agonist activation, and morphological/ cytoskeletal changes upon binding to fibrinogen - before and after activation. (engconfintl.org)
  • Washed PLTs were incubated with IgG fractions from severe COVID-19 ICU or non-COVID-19 ICU patients and analyzed for changes in the expression of caspase 3 using immunoblot as well as CD62P (P-selectin) and phosphatidylserine (PS) via double staining in flow cytometry. (isth.org)
Percentage1
Positive1
  • ICU COVID-19 IgG induced a significant increase in caspase 3 cleavage and formation of CD62P/PS positive procoagulant PLTs compared to the ICU control group (31.63%±3.86 vs. 4.04%±1.16, p= 0.0007). (isth.org)