Peripheral T-cell lymphoma with aberrant expression of CD30, CD15, and CD20. (cityofhope.org)
Whereas, in the LPHD, the cells are CD20-positive and often CD30- and CD15-negative. (targetedonc.com)
Immunohistochemical analysis showed that the LP cells in all cases were positive for CD20, CD79a, PAX5, OCT2, and CD45 and were negative for CD15. (duke.edu)
CD451
Hodgkin cells are CD45 negative, CD30 and CD15 positive. (cap.org)
Welcome to this Targeted Oncology presentation in Precision Medicine called, “Frontline CD30 ADC for Advanced Classic Hodgkin Lymphoma. (targetedonc.com)
Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. (transcriptionfactor.org)
The Reed-Sternberg cells of classical Hodgkin lymphoma are characteristically positive for CD15 and CD30. (blallab.com)
Ligand5
Measured by its ability to block CD30 Ligand-induced IL-6 secretion by HDLM human Hodgkin's lymphoma cells. (transcriptionfactor.org)
The ED50 for this effect is typically 0.5 - 2.5 µg/ml in the presence of 50 ng/ml of Recombinant Human CD30 Ligand. (transcriptionfactor.org)
CD30 Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
This graph shows the total number of publications written about "CD30 Ligand" by people in this website by year, and whether "CD30 Ligand" was a major or minor topic of these publications. (wakehealth.edu)
Below are the most recent publications written about "CD30 Ligand" by people in Profiles. (wakehealth.edu)
Cutaneous1
PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)
MUM11
The cut-off values for these markers were 20% for CD30, and 30% for Bcl-6, MUM1 and PDL1.29C31 Treatment Initial treatments were performed based on the physicians decisions at each institution, as there had been no uniform treatment guidelines for PMBL in Japan. (angiogenesis-blog.com)
Cells5
Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
Expression of the activation marker CD30 may be seen in occasional tumor cells. (webpathology.com)
CD15 is strongly positive within the larger cells. (radiopaedia.org)
The Reed Sterberg cells also have with a specific protein called CD15 or CD30 on them. (lymphoma.org.au)
Markers1
CD15 and CD30 markers are often seen in what underlying malignancy? (knowmedge.com)
Hodgkin's1
Coexpression of CD15 and CD30 (usually associated with classical Hodgkin's lymphoma) may be seen in some PTCL, NOS. (webpathology.com)
Protein1
Human CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. (transcriptionfactor.org)
20221
Spring 2022 has seen the arrival of both the CD15 and CD30 long-life propagation trays. (containerwise.co.uk)
Tumor2
Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. (lookformedical.com)
A membrane-bound tumor necrosis family member found primarily on activated T-LYMPHOCYTES that binds specifically to CD30 ANTIGEN. (wakehealth.edu)
Expression1
The variable expression of CD30 in most of these cases could be the result of EBV infection. (duke.edu)
Activation1
CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. (transcriptionfactor.org)
Cases1
CD30 was expressed variably in 7 cases. (duke.edu)
Large1
And they are identified by a large multinucleated cell sometimes with very prominent nucleoli, and sometimes it looks like a set of owl eyes looking at you, and they are stained positively with CD30 and CD15. (targetedonc.com)
Shows1
Immunohistochemistry shows strong membranous and perigolgi staining with CD30. (radiopaedia.org)
Antigen4
Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
Anaplastic large cell lymphoma CD30/Ki-1 positive, expressing the CD15/Leu-M1 antigen. (unipv.it)
In addition, CD15 antigen is a stage-specific embryonic antigen. (childrensmercy.org)
Cutaneous processes2
CASE REPORT Principal cutaneous anaplastic large-cell lymphoma - Case reportLinfoma cut eo prim io de grandes c ulas anapl icas - Relato de casoLuciana Silveira Rabello de Oliveira1 Maira Gomes MonteiroDOI: http:dx.doi.org10.1590abd1806-4841.Abstract: Principal cutaneous anaplastic large-cell lymphoma is a part of the spectrum of CD30 lymphoproliferative cutaneous processes, characterized by single or multifocal nodules that ulcerate, are autoregressive and recurrent. (5htreceptor.com)
The diagnosis of cutaneous lymphomas is tricky and typically delayed, because of the huge number of differential diagnoses involving the complete spectrum of principal or secondary CD30 cutaneous processes. (5htreceptor.com)
Lymphoproliferative disorders2
PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)
CD30/Ki-1-positive lymphoproliferative disorders of the skin--clinicopathologic correlation and statistical analysis of 86 cases: a multicentric study from the European Organization for Research and Treatment of Cancer Cutaneous Lymphoma Project Group. (unipv.it)
Primary cutaneous1
3. Enhanced PD-L1 expression on tumor cells in primary cutaneous large T-cell lymphoma with CD30 expression as classic Hodgkin lymphoma mimics: A report of lymph node lesions of two cases. (nih.gov)
Antigens3
Antigens, CD15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
This graph shows the total number of publications written about "Antigens, CD15" by people in this website by year, and whether "Antigens, CD15" was a major or minor topic of these publications. (childrensmercy.org)
Below are the most recent publications written about "Antigens, CD15" by people in Profiles. (childrensmercy.org)
Propagation tray1
As of August 2021, the production of a moulding tool, which will produce both a CD15 and CD30 long-life propagation tray is well under way. (containerwise.co.uk)
Trays1
Please keep checking our website and following Charles Dowding on YouTube for updates regarding the launch of the CD15 and CD30 trays, which is anticipated in late 2021/early 2022. (containerwise.co.uk)
Lymphoma1
Lymphoma, T-cell, cutaneous Resumo: Linfoma cut eo prim io de grandes c ulas T anapl icas faz parte do espectro de processos linfoproliferativos cut eos CD30 e caracteriza-se por n ulos icos ou multifocais, ulcerados, autorregressivos e recidivantes. (5htreceptor.com)
Lymphocytes1
CD30-positive large atypical lymphocytes, substantially differ for up-regulated in certain solid tumors and lymphomas. (anyflip.com)