• The precise mechanism for the development of pyogenic granuloma (lobular capillary hemangioma) is unknown. (medscape.com)
  • The cause of the typical pyogenic granuloma (lobular capillary hemangioma) is not known. (medscape.com)
  • Endoglin (CD105), a receptor for transforming growth factor β1, is highly expressed on endothelial cells during tumor angiogenesis and inflammation with weak or negative expression in vascular endothelium of normal tissues. (medscape.com)
  • The purpose of the present study was to investigate the prognostic significance of microvessel density as determined by CD31, a commonly used pan-endothelial marker for microvessel density evaluation, in comparison with endoglin (CD105) on the same group of cases of prostate cancer treated by radical prostatectomy. (medscape.com)
  • [ 2 ] Endothelial nitric oxide synthases (eNOS), CD34, and CD105/endoglin expression are markers of angiogenesis in pyogenic granulomas. (medscape.com)