Cd1 hematopoietic tumor cells. Medical search. Frequent questions

T cell differentiation also continues after they have left the thymus. (wikipedia.org)
The process of differentiation then proceeds to a common lymphoid progenitor (CLP), which can only differentiate into T, B or NK cells. (wikipedia.org)
1. Cancer co-opts differentiation of B-cell precursors into macrophage-like cells. (nih.gov)
14. Macrophages derived from bone marrow modulate differentiation of myeloid dendritic cells. (nih.gov)
The major function of CSFs is to amplify leukopoiesis rather than recruit new stem cells into the granulocyte-monocyte differentiation pathway. (pocketdentistry.com)
Differentiation antigens expressed on pluripotential hematopoietic cells, most human thymocytes, and a major subset of peripheral blood T-lymphocytes. (nih.gov)
Of clinical importance, many lymphoid malignancies appear to be the neoplastic counterparts of cells "arrested" at particular stages of lymphoid differentiation, as judged by cytologic appearance, patterns of growth, immunophenotype, and genetic features. (medilib.ir)
The events that lead to the appearance of cells that are committed to lymphoid differentiation are not completely understood. (medilib.ir)
Subsequently, iNKT cells provide the help required for stimulating B cell proliferation and differentiation. (ox.ac.uk)
The Cx are involved in bi-directional transport of small molecules and are therefore responsible for correct oocyte-somatic cell nutrition, proliferation, and differentiation. (biolifesas.org)
The Cannabinoid signaling regulates cell proliferation, differentiation and it reduces cell aptosis or death. (drcremers.com)
Recently, endocannabinoid (eCB) signaling has also been shown to regulate proliferation and differentiation of hematopoietic and mesenchymal stem cells, with a key role in determining the formation of several cell types in peripheral tissues, including blood cells, adipocytes osteoblasts and osteoclasts, and epithelial cells. (drcremers.com)

Epidermal Langerhans cells (LCs) and dermal dendritic cells (dDCs) capture cutaneous antigens and present them to T-cells in lymph nodes (LNs). (cnrs.fr)
9. Generation of CD1+RelB+ dendritic cells and tartrate-resistant acid phosphatase-positive osteoclast-like multinucleated giant cells from human monocytes. (nih.gov)
13. Granulocyte Macrophage-Colony Stimulating Factor Produces a Splenic Subset of Monocyte-Derived Dendritic Cells That Efficiently Polarize T Helper Type 2 Cells in Response to Blood-Borne Antigen. (nih.gov)
mAb 20-27 (Workshop code 038) recognized a molecule expressed on bovine monocytes and B cells from bovine peripheral blood as well as thymocytes and cells with a dendritic morphology in sections. (ox.ac.uk)
The bovine CD1b molecule is expressed on bovine thymocytes and a proportion of cells with a dendritic morphology in tissue sections. (ox.ac.uk)
In tissue, these antigen-presenting cells are known as dendritic cells (in lymph nodes) or Langerhans cells (in skin and mucosa). (pocketdentistry.com)
is not restricted to any particular cell lineage due to the ubiquitous nature of the retroviral promoter, dendritic cells would be considered the main BM-derived instigator this website of tolerance 41, 42 through uptake and presentation of antigen 43, 44. (micrornasynthesis.com)
However, it has been shown that if dendritic cells can directly express antigen, then tolerance to that antigen can also ensue 45. (micrornasynthesis.com)
this, we suggest that MOG expressed within dendritic cells derived from transduced BM could drive tolerance within the thymus through deletion and/or BCKDHB possibility through the generation of T regulatory cells 46. (micrornasynthesis.com)
Our model will also promote the ectopic AIRE expression in the range of peripherally destined cells such as dendritic cells, macrophages and B cells, and thus cannot be overlooked at this stage as another potential avenue for mechanisms capable of promoting tolerance. (micrornasynthesis.com)
Non-lymphoid cells (eg, dendritic cells, monocytes/macrophages, endothelial cells, pericytes, fibroblasts, and follicular dendritic cells) contribute to the formation of these distinct microenvironments, within which specific cell-cell interactions occur that are required for the generation of cellular and humoral immune responses [ 2 ]. (medilib.ir)

The findings indicate that the six mAbs recognize at least two and possibly four CD1 antigens. (ox.ac.uk)
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. (cusabio.com)
In this study we demonstrate that specific BCR uptake of CD1d-restricted antigens represents an effective means of enhancing invariant natural killer T (iNKT)-dependent B cell responses in vivo. (ox.ac.uk)

5. Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma. (nih.gov)
17. Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages. (nih.gov)
18. An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation. (nih.gov)
No significant association between the ability of iNKT cells to produce IL‑4 or IFN‑γ and the expression of CD1d on leukemic B lymphocytes or monocytes was identified. (spandidos-publications.com)
In their proximate surroundings, neoplastic B cells interact with neighboring cells that include mesenchymal stromal cells, monocytes, monocyte-derived nurse-like cells, and T cells ( 2 ). (spandidos-publications.com)
In addition, monocytes serve as antigen-presenting cells and migrate into tissues. (pocketdentistry.com)

Severely immunodeficient mice engrafted with functional human cells and tissues, known as 'humanized' mice, facilitate progress in studies of human haematopoiesis, immunity, gene therapy, infectious diseases, cancer and regenerative medicine. (nature.com)
Mice homozygous for the severe combined immunodeficiency ( scid ) gene mutation or for targeted mutations at the recombination-activating gene 1 ( Rag1 ) or Rag2 loci, that also have a targeted mutation at the interleukin-2 receptor γ-chain ( Il2rg ) locus, support high levels of engraftment and function of human haematopoietic stem cells (HSCs) and human immune systems. (nature.com)
The development of humanized mice with functional human immune systems (generated by the engraftment of human lymphoid tissues, HSCs or peripheral blood mononuclear cells) provides an opportunity to carry out translational research on human immunity and autoimmune diseases, and for the study of the biology of the human pathogens responsible for AIDS and several other human-specific infectious diseases. (nature.com)
Humanized mice are being used as hosts for primary human tumours for studies of tumour growth and metastasis and for experimental cancer therapy. (nature.com)
The phenotypical and functional characterization of human tumour stem cells is also being advanced through the study of humanized mice. (nature.com)
Significant advances in our understanding of the in vivo functions of human cells and tissues and the human immune system have resulted from the development of 'humanized' mouse strains that are based on severely immunodeficient mice with mutations in the interleukin-2 receptor common γ-chain locus. (nature.com)
Here we comprehensively characterized the kinetics of cell-mediated and humoral immune responses in VRP-vaccinated mice, and demonstrate that they predominantly target the nucleoprotein (NP). (cdc.gov)

Whereas T lymphocytes (T cells) are involved with the delayed, or cellular, immune reaction, B lymphocytes (B cells) play an important role in the immediate, or humoral, immune system involving the production of plasma cells and immunoglobulins (IgA, IgD, IgE, IgG, and IgM). (pocketdentistry.com)
See "The adaptive cellular immune response: T cells and cytokines" and "The adaptive humoral immune response" . (medilib.ir)

Malignant B cells in chronic lymphocytic leukemia serve an essential role in the whole immune response, so their interactions with other immune cells are more complex than observed in solid tumors. (spandidos-publications.com)
In chronic lymphocytic leukemia (CLL), malignant B lymphocytes, similar to other tumor cells, are in constant cooperation with the tumor microenvironment, which is formed by cancer cells through the recruitment and alteration of non-malignant cells of the immune system ( 1 ). (spandidos-publications.com)

4. Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1. (nih.gov)
12. B-Lymphoma cells with epigenetic silencing of Pax5 trans-differentiate into macrophages, but not other hematopoietic lineages. (nih.gov)
CD1a+ CD11b+ macrophages and NK T-cells were found to be significantly increased in inflamed colons of ulcerative colitis patients. (cusabio.com)

There are various limitations in susceptibility, how host susceptibility ies may focus only on specific tumour epidemiological studies (e.g. statis- factors may modulate the impact of outcomes or may not be designed to tical power, exposure assessment, mechanistic events leading to tumour detect some types of tumours). (who.int)

The inhibition of mitochondrial activity by various pharmacological inhibitors, as well as by gene-specific targeting using siRNA-mediated technology showed a dramatic attenuation of polyploidy and bi-nucleation development during in vitro stromal cell decidualization, suggesting mitochondria play a major role in positive regulation of decidual cell polyploidization. (plos.org)
Extracorporeal Shock Waves (ESW), widely used for the treatment of urolithiasis, have been reported to cause modifications of cell growth both in vitro and in vivo. (biolifesas.org)

[ 16-21 ] In addition to adipocytes, several nonadipose sources of leptin have been reported, including trophoblast cells of placenta, the heart, skeletal muscles, endothelial cells and epithelial cells of gastric, colon and mammary origin. (medscape.com)
Group II animals received DMBA (20 mg in 0.5 ml sunflower oil and 0.5 ml of saline) i.p. to develop mammary tumor by the end of 90 days. (propoleo.cl)
Microvesicles loaded with MCs encoding a thymidine kinase (TK)/nitroreductase (NTR) fusion protein produced prolonged TK-NTR expression in mammary carcinoma cells. (regenerativemedicine.net)

All T cells originate from c-kit+Sca1+ haematopoietic stem cells (HSC) which reside in the bone marrow. (wikipedia.org)

A critical step in T cell maturation is making a functional T cell receptor (TCR). (wikipedia.org)
16. Skewing the Th cell phenotype toward Th1 alters the maturation of tumor-infiltrating mononuclear phagocytes. (nih.gov)

Still during the double negative stages, CD34 expression stops and CD1 is expressed. (wikipedia.org)
Expression of both CD4 and CD8 makes them double positive, and matures into either CD4+ or CD8+ cells. (wikipedia.org)
Using peripheral blood iNKT cells obtained from patients with CLL, the objective of the present study was to assess the intracellular expression of typical cytokines involved in the Th1 (IFN‑γ) and Th2 (IL‑4) response pathways following stimulation with the iNKT‑specific ligand α‑galactosylceramide. (spandidos-publications.com)
iNKT cells from patients with CLL exhibited upregulated IL‑4 and IFN‑γ expression in comparison to those from HVs. (spandidos-publications.com)
However, the function of iNKT cells was compromised in patients with CLL by a strong Th2 bias (high IL‑4 and low IFN‑γ expression). (spandidos-publications.com)
In addition, humanized mouse models have benefited greatly from the identification of human species-specific molecules that are crucial for the engraftment and function of human haematopoietic and immune systems and the expression of these molecules in the immunodeficient recipient. (nature.com)
This suggests a cell specific aspect to the expressed AIRE and that AIRE has the general ability to promote the TRA expression regardless of where it may be expressed 34. (micrornasynthesis.com)
In our earlier studies with ectopic expression of MOG, we observed evidence of thymic deletion of MOG35-55-specific T cells 29. (micrornasynthesis.com)
The developmental regulation of cannabinoid receptor expression and cellular/subcellular localization, together with their role in progenitor/stem cell biology, may have important implications in human health and disease. (drcremers.com)
We demonstrated that MCs can be loaded into shed microvesicles with greater efficiency than their parental plasmid counterparts and that microvesicle-mediated MC delivery led to significantly higher and more prolonged transgene expression in recipient cells than microvesicles loaded with the parental plasmid. (regenerativemedicine.net)

lymphoid tissue, and digestive tract), which the animal model captures the It can be difficult to parse out concordance has often been ob- range of potential human response reasons for lack of tumour site con- served among different species after to the particular agent tested. (who.int)
For instance, if you can increase the numbers and movement of stem cells to an injured tissue, you could vastly enhance the healing process. (drcremers.com)

Unlike conventional T lymphocytes, they express markedly less variable T cell receptors (TCRαβ), and are formed by an invariant α chain (Vα24Jα18) combined with a limited set of β chains, mainly containing Vβ11 ( 7 - 9 ). (spandidos-publications.com)
Using such TCR receptors, iNKT cells recognize lipids and glycolipids, presented by a non-classical MHC molecule known as CD1d ( 10 ). (spandidos-publications.com)
They have been implicated in integrin-mediated cellular adhesion and as signalling receptors on T-cells. (nih.gov)
Bone marrow and stem cells make endocannabinoids, these endocannabinoids interact with the cannabinoid receptors (Cannabinoid receptors have been found in nearly every cell in the human body). (drcremers.com)

After migration to the thymus, the precursor cells mature into several distinct types of T cells. (wikipedia.org)

This enables iNKT cells to influence other cells of the immune system, including NK cells, cytotoxic T lymphocytes, helper T cells, B cells and antigen presenting cells (APC) ( 17 - 19 ). (spandidos-publications.com)

Henceforth they are known as thymocytes, the immature stage of a T cell. (wikipedia.org)
To become T cells, the thymocytes must undergo multiple DN stages as well as positive selection and negative selection. (wikipedia.org)

Blood has many functions, including transporting oxygen and nutrients to tissues, removing waste materials (e.g., carbon dioxide, urea ), regulating body temperature, and carrying cells responsible for coagulation and immune response . (amboss.com)
Comparison of CD1 monoclonal antibodies on bovine cells and tissues. (ox.ac.uk)
Blood forming cells first appear in the yolk sac around day 16 of gestation, but yolk sac hematopoiesis is restricted to the production of primitive red cells, platelets, and monocyte/macrophage-like progenitors that home to tissues and give rise to specialized long-lived phagocytes such as Kupffer cells in the liver and microglia in the brain [ 4,5 ]. (medilib.ir)
Progenitor cells from these tissues populate the thymus by seven to eight weeks of gestation. (medilib.ir)
However, the application of certain molecular techniques often leads to destabilization or destruction of the materials of interest, such as cells or whole tissues. (biolifesas.org)

T cells are born from hematopoietic stem cells, found in the bone marrow. (wikipedia.org)
White blood cells released by the bone marrow that circulate in the peripheral blood account for only 5% of the total WBC mass and form two pools of cells: (1) marginal and (2) circulating. (pocketdentistry.com)
Bone marrow hematopoiesis commences by about five months of gestation and under normal circumstances is the primary source of hematopoietic cells after birth. (medilib.ir)
RESULTS: CAPE entered CT26 cells rapidly and depleted intracellular GSH in CT26 cells, but not in bone marrow cells. (propoleo.cl)

No correlation was found between GHS concentrations and formaldehyde-induced cell toxicity, revealing that the homologous recombination pathway rather than the NHEJ pathway is involved in repair of DNA-protein crosslinks (DPC). (europa.eu)
Upstream and downstream components of the FA DNA-repair pathway were tested using mutant chicken DT40 cell lines. (europa.eu)
Mutations in all components of the FA pathway tested sensitized cells to formaldehyde. (europa.eu)

There are several stage, lifestyle, sex, and the impact late-developing tumours, or studies other tumour sites with fewer, or less of co-exposures. (who.int)

The microbiome may lack statistical power to detect common, tumour site concordances can also play a critical part in host an increase in tumour incidence at among the species studied. (who.int)

In the receptive uterus on day 4 of pregnancy (day 1 = vaginal plug), the onset of embryo implantation elicits the prerequisite transformation of stromal cells into decidual cells (decidualization), which is a gateway to pregnancy establishment. (plos.org)

In the present study, to better define the aspects of decidual cell polyploidy, we isolated pure polyploid and non-polyploid decidual cell populations from the in vivo decidual bed. (plos.org)
CD207(+)CD1a(+) cells are circulating in patients with active Langerhans cell histiocytosis, and TSLP and TGF-beta are potential drivers of Langerhans-like cells in vivo. (cusabio.com)
B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo. (ox.ac.uk)
BALB/c mouse with CT26 cells implantation was used as a syngeneic in vivo model for evaluation of treatment and toxicity end points. (propoleo.cl)
In vivo delivery of TK-NTR and administration of prodrugs led to the effective killing of both targeted cells and surrounding tumor cells via TK-NTR-mediated conversion of co-delivered prodrugs into active cytotoxic agents. (regenerativemedicine.net)
In vivo evaluation of the bystander effect in mouse models demonstrated that for effective therapy, at least 1% of tumor cells need to be delivered with TK-NTR-encoding MCs. (regenerativemedicine.net)
In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators. (docksci.com)
In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Wen-Hui Lien1,5 , Lisa Polak1 , Mingyan Lin2 , Kenneth Lay1 , Deyou Zheng2,3,4 and Elaine Fuchs1,6 Hair follicle stem cells (HFSCs) regenerate hair in response to Wnt signalling. (docksci.com)

These are named for the presence of the cell surface proteins CD8 or CD4. (wikipedia.org)
CD8+ T cells are also able to use small signalling proteins, known as cytokines, to recruit other types of cells when mounting an immune response. (wikipedia.org)
The main proteins involved in this process belong to the connexin (Cx) family, which are responsible for the formation of gap junction (GJC) connections between the female gamete and surrounding somatic cells. (biolifesas.org)

The role of iNKT in tumor immunity is only partially understood and is poorly described in CLL. (spandidos-publications.com)

Activated iNKT cells simultaneously secrete interferon (IFN)-γ and interleukin (IL)-4 ( 14 ). (spandidos-publications.com)
Certain pathological conditions may cause a change in the Th0-like pattern of cytokines secreted by iNKT cells and polarize their response in the Th1 or Th2 direction ( 10 , 20 ). (spandidos-publications.com)
Such iNKT cells can modify the microenvironment and influence tumor control ( 21 ). (spandidos-publications.com)
Thus, we have demonstrated that in response to particulate antigenic lipids iNKT cells are recruited for the assistance of B cell activation, resulting in the enhancement of specific antibody responses. (ox.ac.uk)

One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. (wikipedia.org)
CD8+ T cells, also known as "killer T cells", are cytotoxic - this means that they are able to directly kill virus-infected cells, as well as cancer cells. (wikipedia.org)
Unlike CD8+ killer T cells, the CD4+ helper T (TH) cells function by further activating memory B cells and cytotoxic T cells, which leads to a larger immune response. (wikipedia.org)

Wnt signalling can also stimulate stem cell maintenance in cultures of haematopoeitic stem cells5 and embryonic stem cells6 (ESCs). (docksci.com)

This unique cell subset combines features of T lymphocytes and NK cells ( 6 ). (spandidos-publications.com)
It is generally agreed that HSCs first give rise to multipotent progenitors (MPPs), a subset of which retain the capacity to produce either myeloid or lymphoid cells [ 10,11 ]. (medilib.ir)

MiRNAs are abundant in many mammalian cell types. (micrornasynthesis.com)

If cannabinoids can enhance stem cell migration and proliferation, this could be a powerful therapy. (drcremers.com)

Assessment of DNA damage response to plasma levels of formaldehyde in chicken DT40 and colorectal cancer (RKO) cells with targeted mutations in various DNA repair genes. (europa.eu)
Based on functional enrichment analyses, up-regulated polyploidy genes appeared to implicate several functions, which primarily include cell/nuclear division, ATP binding, metabolic process, and mitochondrial activity, whereas that of down-regulated genes primarily included apoptosis and immune processes. (plos.org)

Flow cytometric data with mAbs CC40 (039) and CC122 (043) were not sufficiently similar to data with mAb CC20 to allow the two mAbs to be regarded as CD1b although they did appear to be directed against bovine CD1 molecules. (ox.ac.uk)

We have previously demonstrated in the mouse that mAbs against C-type lectins administered intradermally are taken up by epidermal Langerhans cells (LCs), dermal Langerin(neg) DCs, and dermal Langerin(+) DCs in situ. (cnrs.fr)

These interactions provide B cell clones with supporting factors that inhibit or delay programmed apoptosis and thereby sustain disease progression ( 3 ). (spandidos-publications.com)

The specific adaptive immune response regulated by the TH cell depends on its subtype (such as T-helper1, T-helper2, T-helper17, regulatory T-cell), which is distinguished by the types of cytokines they secrete. (wikipedia.org)
The dialogue between CLL B cells and interacting T lymphocytes may involve cytokines ( 4 ). (spandidos-publications.com)
In addition, they can release other pro-inflammatory Th1 cytokines [such as tumor necrosis factor (TNF)-α and IL-6] and anti-inflammatory Th2 cytokines [such as IL-10, IL-13 and transforming growth factor (TGF)-β] ( 14 - 16 ). (spandidos-publications.com)
In lipopolysaccharide-stimulated human dermal fibroblast, BEAS-2B, A549, and THP-1 cells, EISO suppressed total cellular PDE activity, PDE4, and 7 transcript levels, nuclear factor kappa B (NF-κB) activation, and pro-inflammatory cytokines/chemokine production. (frontiersin.org)
However, numerous environmental and genetic factors contribute to these cytokine-mediated chronic skin conditions, and it is difficult to differentiate PS and AD during the acute erythrodermic phase since both are caused by aberrant production of inflammatory cytokines/chemokines by keratinocytes and innate and adaptive immune cell populations ( Schafer, 2012 ). (frontiersin.org)

T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. (wikipedia.org)
The present study focused on a population of T lymphocytes, known as invariant natural killer T cells (iNKT) ( 5 ). (spandidos-publications.com)
Lymphocytes include cells that are responsible for both the innate (natural killers) and adaptive ( T and B cells ) immune system . (amboss.com)
Circulating lymphocytes are of three types: T lymphocytes (thymus mediated), B lymphocytes (bursa derived), and natural killer (NK) cells. (pocketdentistry.com)
Within these lymphoid organs, B and T lymphocytes tend to home to different domains, leading to the segregation of B and T cells. (medilib.ir)

Disorders of white blood cells (WBCs) in dental patients can substantially influence clinical decision making as well as the delivery of care because WBCs constitute the primary defense against microbial infections and are critical for mounting an immune response ( Box 23.1 ). (pocketdentistry.com)

These cells bud off from "hemogenic endothelium" but are clonally distinct from aortic endothelial cells [ 6-8 ]. (medilib.ir)

The newly arrived CLP cells are CD4−CD8−CD44+CD25−ckit+ cells, and are termed early thymic progenitor (ETP) cells. (wikipedia.org)

The earliest cells which arrived in the thymus are commonly termed double-negative, as they express neither the CD4 nor CD8 co-receptor. (wikipedia.org)
The earliest committed hematolymphoid progenitors are derived through asymmetric cell divisions, in which undifferentiated HSCs give rise to daughter cells with greater proliferative potential but lacking the property of self-renewal. (medilib.ir)

Beta-2 microglobulin (B2M) is an immune system protein that is found on the surface of all nucleated human cells. (bvsalud.org)
Human blood consists of blood cells and plasma. (amboss.com)
mAb CC20 (033) was shown to stain COS cells transfected with human CD1b cDNA and this mAb together with CC14 (not in workshop panel) and CC90 (007), which gave identical staining by flow cytometry and immunohistology, should all be regarded as being bovine CD1b mAb. (ox.ac.uk)
Thus cells of human origin showed similar hypersensitivity to formaldehyde. (europa.eu)
Earlier results indicating increased sensitivity to formaldehyde in FANCB-deficient cells were validated by testing a human FA gene-deficient cell line (human B cell line NALM-6). (europa.eu)
India root spice and the 'herbal' medicine propolis, on HL-60 human leukaemia cell survival is characterised. (propoleo.cl)

and their precursors as well as by various non-hematopoietic cells. (nih.gov)

A thymocyte can only become an active T cell when it survives the process of developing a functional TCR. (wikipedia.org)
Collectively, analyses of unique polyploidy markers and molecular signaling networks may be useful to further characterize functional aspects of decidual cell polyploidy at the site of implantation. (plos.org)
and (3) a storage pool of functional cells, which can be released as needed. (pocketdentistry.com)

For this reason, these regulatory T cells have also been called "suppressor" T cells. (wikipedia.org)
These same regulatory T cells can also be co-opted by cancer cells to prevent the recognition of, and an immune response against, tumor cells. (wikipedia.org)

The latest study results indicate that the immune dysregulation in chronic lymphocytic leukemia (CLL) also affects a small population of invariant natural killer T cells (iNKT). (spandidos-publications.com)

Highly regulated activation of B cells is required for the production of specific antibodies necessary to provide protection from pathogen infection. (ox.ac.uk)
iNKT-stimulated B cells develop within extrafollicular foci and mediate the production of high titers of specific IgM and early class-switched antibodies. (ox.ac.uk)

Increases in intragastric pH may result in hypergastrinemia and enterochromaffin-like cell hyperplasia and increased chromogranin A levels which may interfere with diagnostic investigations for neuroendocrine tumors. (nih.gov)

T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. (wikipedia.org)

See "Overview of stem cells", section on 'What defines a stem cell?' . (medilib.ir)
Research focus in hematopoietic stem cell transplantation and Treg cell immunotherapy, with an emphasis on the treatment of graft-versus-host disease as well as immune tolerance induction for transplantation and autoimmunity. (stanfordhealthcare.org)
Will I prescribe medical marijuana for my stem cell patients? (drcremers.com)
However, in the quiescent stem cell niche of the adult hair follicle, LEF1-TCF Wnt reporter (TOPGAL) activity has not been observed7,8 , suggesting that if Wnt-β-catenin signalling is required universally to maintain stem cells, it acts through promoting activation rather than viability. (docksci.com)

Macrocyclic trichothecenes bring about neuronal cell apoptosis and inflammation in the olfactory epithelium and olfactory bulb. (mdpi.com)

This prevents immune cells from inappropriately reacting against one's own cells, known as an "autoimmune" response. (wikipedia.org)

Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. (wikipedia.org)

The role of these cells in the pathogenesis and clinical course of CLL is not well known. (spandidos-publications.com)
However, the role of the granulosa cells in acquisition of MII stageand/or full fertilization ability is not yet entirely known. (biolifesas.org)

Anatomy24

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Phenomena and Processes42

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