Chemicals and DrugsPhenomena and Processes
CCAAT-Enhancer-Binding Protein-deltaCCAAT-Enhancer-Binding ProteinsCCAAT-Enhancer-Binding Protein-alphaCCAAT-Enhancer-Binding Protein-betaEnhancer Elements, GeneticPromoter Regions, GeneticDNA-Binding ProteinsTranscription FactorsNuclear Proteins
CebpdSubunitKinaseELISA KitEpsilonIsoformsGenesLeucine zipperAdipocyte differentiationReceptorEBPbetaPromoterMRNAsMotifsBrown adiposTranscriptionalAntibodiesMRNAAntibodyTranscription FactorsGeneCassetteCREBHeat shock proteinBetaHeterodimersHumansAnnotationNuclearExpressionAlphaFactorPeptideComplexCellComplexesSequenceRoleHuman
Cebpd1
  • CCAAT/enhancer-binding protein delta is a protein that in humans is encoded by the CEBPD gene. (wikipedia.org)
Subunit2
  • METHODS: We report on a protein subunit vaccine comprising the receptor-binding domain (RBD) of the ancestral SARS-CoV-2 spike protein, dimerised with an immunoglobulin IgG1 Fc domain. (bvsalud.org)
  • INTERPRETATION: These results demonstrated that an RBD-Fc protein subunit/MF59® adjuvanted vaccine can induce high levels of broadly reactive nAbs, including when used as a booster following prior immunisation of mice with whole ancestral-strain spike vaccines. (bvsalud.org)
Kinase5
  • death associated protein kinase 1 [Sou. (gsea-msigdb.org)
  • Description: A sandwich quantitative ELISA assay kit for detection of Human Casein Kinase 1 Delta (CSNK1d) in samples from tissue homogenates or other biological fluids. (1elisakits.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Casein Kinase 1 Delta (CSNK1d) in Tissue homogenates and other biological fluids. (1elisakits.com)
  • Description: A sandwich ELISA kit for detection of Casein Kinase 1 Delta from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (1elisakits.com)
  • Bae KM, Wang H, Jiang G, Chen MG, Lu L, Xiao L. Protein kinase C epsilon is overexpressed in primary human non-small cell lung cancers and functionally required for proliferation of non-small cell lung cancer cells in a p21/Cip1-dependent manner. (famri.org)
ELISA Kit2
  • Description: A sandwich ELISA kit for detection of GRB2 Related Adaptor Protein 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (therabio.org)
  • Description: A sandwich ELISA kit for detection of G Protein Coupled Receptor 172A from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (myelisakit.com)
Epsilon1
  • 2014. Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice. . (oregonstate.edu)
Isoforms1
  • Analysis of mRNA for three isoforms of the CCAAT/enhancer binding protein (C/EBP) revealed that TCDD (5 nM) selectively inhibited the induction of C/EBP alpha mRNA but did not block the induction of C/EBP beta and C/EBP delta in response to differentiation inducers. (aspetjournals.org)
Genes3
  • The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. (wikipedia.org)
  • We also found new transcription factors and target genes, such as CCAAT/enhancer-binding protein delta and JunB, responsible for inflammatory cardiomyopathy. (geneticsmr.com)
  • A substantial portion of the regulatory interactions in the higher eukaryotic cell are mediated by simple sequence motifs in the regulatory segments of genes and (pre-)mRNAs, and in the intrinsically disordered regions of proteins. (biomedcentral.com)
Leucine zipper1
Adipocyte differentiation1
  • Alteration by 2,3,7,8-Tetrachlorodibenzo-p-dioxin of CCAAT/enhancer binding protein correlates with suppression of adipocyte differentiation in 3T3-L1 cells. (aspetjournals.org)
Receptor2
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human G Protein Coupled Receptor 172A (GPR172A) in Tissue homogenates, saliva and other biological fluids. (myelisakit.com)
  • Description: A sandwich quantitative ELISA assay kit for detection of Human G Protein Coupled Receptor 120 (GPR120) in samples from tissue homogenates, cell lysates or other biological fluids. (myelisakit.com)
EBPbeta1
  • Here, we identify a CCAAT/Enhancer Binding Protein beta (C/EBPbeta) binding site in the RIG-I promoter as a repressor element, and show that NS1 promotes C/EBPbeta phosphorylation and its recruitment to the RIG-I promoter as a C/EBPbeta/NS1 complex. (cdc.gov)
Promoter2
  • Subsequently, truncation and mutation of a vimentin promoter demonstrated that HDAC1‑induced vimentin expression was dependent on a nuclear factor κ‑light‑chain‑enhancer of activated B cells (NF‑κB) binding site in the vimentin promoter sequence. (spandidos-publications.com)
  • We have previously reported that C/EBP beta specifically binds to the CRE on the proximal Pgc-1 alpha promoter and increases forskolin-sensitive Pgc-1 alpha and Ucp1 expression in white 3T3-L1 preadipocytes. (elsevierpure.com)
MRNAs3
  • Cellular identity is determined by the transcriptional profile which comprises the subset of mRNAs, and therefore proteins, being expressed by a cell at a given point in time. (silverchair.com)
  • MicroRNAs regulate gene expression at the post-transcriptional level by binding to 3′- or less often to 5′-untranslated regions of target messenger RNAs (mRNAs), which in consequence leads to inhibited translation and/or induces degradation of targeted mRNA [ 1 ]. (archivesofmedicalscience.com)
  • Finally, we contrast the regulatory properties of protein motifs and the regulatory elements of DNA and (pre-)mRNAs, advocating that co-regulation, co-operativity, and motif-driven regulatory programs are common mechanisms that emerge from the use of simple, evolutionarily plastic regulatory modules. (biomedcentral.com)
Motifs1
  • We observe that each gene and its products have a unique set of DNA, RNA or protein motifs that encode a regulatory program to define the logical circuitry that guides the life cycle of these biomolecules, from transcription to degradation. (biomedcentral.com)
Brown adipos1
  • Avian species do not have brown adipose tissue (BAT), and lack Uncoupling Protein 1 ( UCP1 ) [ 12 ]. (biomedcentral.com)
Transcriptional1
  • We also found that ER-α interacts with Dlx3 and increases its transcriptional activity and DNA binding affinity. (molcells.org)
Antibodies2
  • Immunoblot analysis with specific antibodies to each C/EBP isoform demonstrated that the levels of C/EBP delta and C/EBP beta protein were rapidly induced (by day 1) and then abrogated by day 4 and 8, respectively, in solvent-treated (control) cells. (aspetjournals.org)
  • Seasonal vaccination induced cross-reactive neuraminidase inhibition and binding antibodies to N9, but minimal cross-reactive antibody-dependent cell-mediated cytotoxicity (ADCC) antibodies to A(H7N9). (cdc.gov)
MRNA3
  • Exposure of isolated human adipocytes to tumor necrosis factor-α (TNF-α) produced a marked and specific decrease in the mRNA encoding the SREBP1c isoform and completely blocked the insulin-induced cleavage of SREBP1 protein. (diabetesjournals.org)
  • A microRNA strand is transferred to the Argonaute complex (AGO), forming an RNA-induced silencing complex (RISC), and guides it to pair with the target mRNA through binding of the microRNA seed sequence with the microRNA recognition site on the mRNA. (archivesofmedicalscience.com)
  • HDAC1 and vimentin were significantly increased in HCC cells, and HDAC1 overexpression enhanced vimentin mRNA and protein expression levels in an HDAC1 dose‑dependent manner. (spandidos-publications.com)
Antibody3
  • These T cells act in concert to suppress systemic antibody production induced by therapeutic protein administration. (bvsalud.org)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human GRB2 Related Adaptor Protein 2 (GRAP2) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (therabio.org)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat High Density Lipoprotein Binding Protein (HDLBP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids. (tuberculosistest.net)
Transcription Factors1
Gene2
  • The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. (wikipedia.org)
  • Influenza virus non-structural protein 1 (NS1) counteracts host antiviral innate immune responses by inhibiting Retinoic acid inducible gene-I (RIG-I) activation. (cdc.gov)
Cassette1
CREB3
  • CREB binding protein [Source:HGNC Symb. (gsea-msigdb.org)
  • Employing chromatin immunoprecipitation, we demonstrate that C/EBP beta, CREB, ATF-2, and CHOP10 are bound to the Pgc-1 alpha proximal CRE, but CHOP10 does not bind in HIB-1B cell lysates. (elsevierpure.com)
  • Forskolin stimulation and C/EBP beta overexpression in 3T3-L1 cells increased C/EBP beta and CREB but displaced ATF-2 and CHOP10 binding to the Pgc-1 alpha proximal CRE. (elsevierpure.com)
Heat shock protein1
Beta5
  • amyloid beta precursor protein binding. (gsea-msigdb.org)
  • 2002. Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). . (oregonstate.edu)
  • Joining regarding filtered Gt in order to photoactivated Rho (Rho*) in n-dodecyl beta-D-maltoside (DDM) reviewed by simply serum filtration chromatography was normally modest, as well as filtered complexes offered heterogeneous percentages associated with necessary protein factors, more than likely as a consequence of excessive soap. (gw786034inhibitor.com)
  • In TCDD-treated cells, however, the levels of C/EBP beta and C/EBP delta protein persisted at these time points. (aspetjournals.org)
  • Here we show that in mice exposed to a cold environment for 24 h, Pgc-1 alpha, Ucp1, and C/ebp beta but not C/ebp alpha or C/ebp delta expression were increased in BAT. (elsevierpure.com)
Heterodimers2
  • It can also form heterodimers with the related protein CEBP-alpha. (wikipedia.org)
  • Binds DNA as a dimer and can form stable heterodimers with C/EBP delta. (lu.se)
Humans2
  • Rice Protein Matrix Enhances Circulating Levels of Xanthohumol Following Acute Oral Intake of Spent Hops in Humans. (oregonstate.edu)
  • and 3) describing the functions of cholesteryl ester transfer protein (CETP) in regulating the LDL:HDL ratio in humans, including therapeutic strategies targeting CETP. (biomedcentral.com)
Annotation1
  • This calls for extensive identification and annotation of key AR-dependent proteins and a delineation of the mechanistic action of AR. (biomedcentral.com)
Nuclear1
  • Gel shift analysis of nuclear extract binding to an oligonucleotide containing a C/EBP DNA recognition sequence revealed no difference between extracts from control and TCDD-treated cells in the binding pattern at day 2 of differentiation. (aspetjournals.org)
Expression1
  • Previous studies have demonstrated that vimentin expression is associated with HCC progression and that the serum vimentin level may serve as an additional marker of HCC, suggesting a role of vimentin protein in HCC pathogenesis ( 20 - 22 ). (spandidos-publications.com)
Alpha2
  • Furthermore, when used as a heterologous third dose booster, the RBD-Fc vaccines combined with MF59® increased titres of nAb against other variants including alpha, delta, delta+, gamma, lambda, mu, and omicron BA.1, BA.2 and BA.5. (bvsalud.org)
  • In contrast, C/EBP alpha protein was markedly suppressed by TCDD in concordance with its level of RNA. (aspetjournals.org)
Factor1
  • Sterol regulatory element binding protein (SREBP)-1 is a transcription factor with important roles in the control of fatty acid metabolism and adipogenesis. (diabetesjournals.org)
Peptide1
  • Whilst both FoxP3+LAP+ and FoxP3-LAP+ CD4+ T cells express membrane-bound TGF-ß (latency associated peptide, LAP), phenotypic, functional, and single cell transcriptomic analyses reveal distinct characteristics in the two subsets. (bvsalud.org)
Complex1
  • Rho*-Gt complex stableness as well as task ended up greatly increased through addition of phospholipids such as DOPC, DOPE, and DOPS and also asolectin in order to detergent-containing remedies of such healthy proteins. (gw786034inhibitor.com)
Cell1
  • Herein, we document remoteness issues that boost the stableness along with sustain the adventure and suitable stoichiometry regarding profitable complexes between your purified prototypical GPCR, rhodopsin (Rho), and also the rod cell-specific Gary protein, transducin (Gt bike). (gw786034inhibitor.com)
Complexes1
  • After translation, where is a protein localised, and what complexes should it join? (biomedcentral.com)
Sequence1
  • All six members of this family exhibit a high sequence similarity in their C-terminal DNA binding domain and a more diverge regulatory N-terminus [ 1 , 2 ]. (biomedcentral.com)
Role2
  • It has been shown that C/EBPβ plays an important role in the consolidation of long-term memory, suggesting a very important role for this protein in the hippocampus [ 10 , 11 ] and Menard et al . (biomedcentral.com)
  • This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to cognitive impairment and dementia (VCID). (biomedcentral.com)
Human1
  • It is estimated that microRNAs regulate production of approximately 60% of all human proteins and enzymes that are responsible for major physiological processes. (archivesofmedicalscience.com)