• He was involved in the early research and discovery of caveolins and the identification and characterization of cavins as major structural components of caveolae. (wikipedia.org)
  • Lipid uptake occurs through caveolae, plasma membrane invaginations formed by caveolins (CAV) and caveolae-associated protein 1 (CAVIN1). (aacrjournals.org)
  • Caveolins can serve as protein markers of caveolae ('little caves'), invaginations in the plasma membrane 50-100 nanometers in diameter. (biomedcentral.com)
  • Exploring the caves: cavins, caveolins and caveolae. (cam.ac.uk)
  • In Caveolins and Caveolae: Roles in Signaling and Disease Mechanisms (pp. 51-62). (elsevierpure.com)
  • The precise functions of caveolae and their main constituent proteins caveolins (Cav 1-3) and cavins (1-4) remain unresolved. (uam.es)
  • Caveolins (including CAV1, CAV2, CAV3) are structural components of a cell that regulate various proteins involved in the cell's ability to function properly. (sciencedaily.com)
  • The outer surface of these vesicles are covered with a lattice-like network of coat proteins, such as CLATHRIN, coat protein complex proteins, or CAVEOLINS. (lookformedical.com)
  • Recent research claim that caveolins work as scaffolding protein to connect to signalling substances like G-proteins, receptor tyrosine kinases (RTKs), Src-like kinases, eNOS, ERK and Ras [17, 18]. (ampkpathway.com)
  • In this regard, it is noteworthy that caveolin is a component of several intracellular vesicle populations, caveolin 1 is required for lipid droplets formation, and all forms of caveolins i. (viterlabs.com.ar)
  • Caveolins (Cavs) are regulators of neuronal and glial survival signaling. (escholarship.org)
  • Caveolins are found predominantly at the plasma membrane but also in the Golgi, the endoplasmic reticulum, in vesicles, and at cytosolic locations. (biomedcentral.com)
  • Human PTRF mutations may cause secondary deficiency of caveolins, resulting in generalized lipodystrophy in association with in muscular dystrophy. (medscape.com)
  • Expression of NTPDase and caveolins in human cardiovascular disease. (otka-palyazat.hu)
  • Therefore, caveolins are recognized to play a dynamic part in a number of mobile procedures [20, 21]. (ampkpathway.com)
  • also known as cavin) is a caveolar-associated protein suggested to play an essential role in the formation of caveolae and the stabilization of caveolins. (nih.gov)
  • He was involved in the early research and discovery of caveolins and the identification and characterization of cavins as major structural components of caveolae. (wikipedia.org)
  • Caveolins are the principal protein components of caveolae, invaginations of the plasma membrane involved in cell signaling and trafficking. (nih.gov)
  • Caveolins are the principal components of caveolae membranes. (embl.de)
  • It is not yet clear whether expression of caveolins or caveolae numbers change with age in the outflow tract or retina, but this is an area of interest in my laboratory. (brightfocus.org)
  • Each of these CID Caveolins And Caveolae: Roles In Signaling And Disease Mechanisms 2012 countries can do personalised also or in hervorragend in with the adjacent vacuum ledger 62, 63, 64 and 65. (pompello.com)
  • 14. Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. (nih.gov)
  • Aquaglyceroporins have already been connected with caveolins as essential membrane protein implicated in preserving metabolic and energy homeostasis [46]. (biodiversityhotspot.org)