• In its mildest form, impaired regional cerebral blood flow causes a transient ischemic attack (TIA). (vin.com)
  • A number of classification systems for ischemic stroke have been proposed in humans. (vin.com)
  • The most commonly used clinical systems divide ischemic stroke into three major stroke subtypes: large artery or atherosclerotic infarctions, cardioembolic infarctions and small vessel or lacunar infarctions. (vin.com)
  • Occurrence of a stroke or embolic transient ischemic attack occurring 48 hours after the surgery were the outcome measures. (hcplive.com)
  • Twenty-seven patients had an embolic event during the time between valve replacement and echocardiographic study (mean, 69.4 ± 67 months), of which 19 were ischemic strokes, five were peripheral embolisms, and three were transient ischemic attacks. (hcplive.com)
  • Meeting six or all seven CHMs is associated with a lower risk for all-cause, CVD, and ischemic heart disease mortalities compared with the risk to persons who meet none or only one CHM ( 3 ). (cdc.gov)
  • In another study, the Women Estrogen Stroke Trial, 17 beta estradiol 1 mg/placebo was administered to women with previous ischemic stroke or transient ischaemic attack (TIA) having a mean age 71. (eurekaselect.com)
  • In the hormone replacement therapy (HRT) arm there was a 29% increased rate of ischemic stroke (Number Needed to Harm, NNH:147). (eurekaselect.com)
  • The objective of this study was to investigate the mechanism by which rivaroxaban reduces cerebral hemorrhage in mice with TPA ischemic stroke after thrombolysis. (researcherslinks.com)
  • Salt reduction was recommended as one of the top three priority actions to reduce premature mortality from NCDs by 25% by 2025 (3,4). (who.int)
  • Cardiovascular disease (CVD) accounts for one of every three deaths in the United States, making it the leading cause of mortality in the country ( 1 ). (cdc.gov)
  • A definitive answer as to which of these three techniques achieves the best outcomes in these patients awaits the results of the MISTIE III, INVEST and ENRICH trials, but optimism is growing that hematoma reduction using MIS techniques could begin to reduce ICH-related mortality and disability. (bcst.md)
  • Prespecified primary end points were all stroke, disabling stroke, nondisabling stroke, and all-cause mortality. (imperial.ac.uk)
  • I2 = 0%) but did not affect all stroke, nondisabling stroke, or all-cause mortality. (imperial.ac.uk)
  • BACKGROUND AND PURPOSE: Stroke mortality has been declining since the early 20th century. (cdc.gov)
  • As a result of recent striking and more accelerated decreases in stroke mortality, stroke has fallen from the third to the fourth leading cause of death in the United States. (cdc.gov)
  • This has prompted a detailed assessment of the factors associated with the change in stroke risk and mortality. (cdc.gov)
  • RESULTS: The decline in stroke mortality over the past decades represents a major improvement in population health and is observed for both sexes and for all racial/ethnic and age groups. (cdc.gov)
  • The decline in mortality results from reduced incidence of stroke and lower case-fatality rates. (cdc.gov)
  • Although it is difficult to calculate specific attributable risk estimates, efforts in hypertension control initiated in the 1970s appear to have had the most substantial influence on the accelerated decline in stroke mortality. (cdc.gov)
  • Although implemented later, diabetes mellitus and dyslipidemia control and smoking cessation programs, particularly in combination with treatment of hypertension, also appear to have contributed to the decline in stroke mortality. (cdc.gov)
  • CONCLUSIONS: The decline in stroke mortality is real and represents a major public health and clinical medicine success story. (cdc.gov)
  • The repositioning of stroke from third to fourth leading cause of death is the result of true mortality decline and not an increase in mortality from chronic lung disease, which is now the third leading cause of death in the United States. (cdc.gov)
  • Despite decades-long reductions in cardiovascular disease (CVD) mortality, CVD mortality rates have recently plateaued and even increased in some subgroups, and the prevalence of CVD risk factors remains high. (cdc.gov)
  • Despite steady declines in CVD mortality rates over approximately the last 40 years, heart disease and stroke remain the first and fifth leading causes of death in the United States, respectively, and their associated mortality rates have recently begun to plateau in the general population and even increase among some subpopulations. (cdc.gov)
  • Cardiac disease remains the leading cause of mortality in type 2 diabetes, yet few strategies to target cardiac dysfunction have been developed. (constantcontact.com)
  • Despite medical advances in its diagnosis and management, DKA remains an important cause of hospital admissions and mortality in children and adults, particularly in developing countries. (lww.com)
  • If perioperative death were to constitute its own category in the annual US mortality tables, it would represent the third leading cause of death. (medscape.com)
  • Cardiac complications constitute a major cause of postoperative morbidity and mortality in surgical patients. (medscape.com)
  • In recent decades, cancer mortality attributable to tobacco smoking has increased in the elderly, while stroke mortality attributable to high blood pressure has declined. (who.int)
  • Stroke volume is an important determinant of cardiac output, which is the product of stroke volume and heart rate, and is also used to calculate ejection fraction, which is stroke volume divided by end-diastolic volume. (wikipedia.org)
  • Reduced afterload , which enhances ventricular stroke volume and improves ejection fraction. (cvpharmacology.com)
  • Omecamtiv mercabil increased left ventricular ejection time and stroke volume compared to control, alongside a small reduction in heart rate, suggesting that the hearts were working more effectively and efficiently. (pharmatimes.com)
  • Emerging data suggest that chronic training for and competing in extreme endurance events such as marathons, ultramarathons, ironman distance triathlons, and very long distance bicycle races, can cause transient acute volume overload of the atria and right ventricle, with transient reductions in right ventricular ejection fraction and elevations of cardiac biomarkers, all of which return to normal within 1 week. (nih.gov)
  • Reduced heart rate prolongs ventricular diastole (filling), increasing end-diastolic volume, and ultimately allowing more blood to be ejected. (wikipedia.org)
  • Defects in Notch signaling also cause inherited cardiovascular diseases, such as Left Ventricular Non-compaction and Alagille syndrome ( 4 , 7 , 22 ). (frontiersin.org)
  • 2] Systolic dysfunction is characterized by diminished ventricular contractility that results in an impaired ability to increase the stroke volume to meet systemic demands. (medscape.com)
  • Causes of primary diastolic dysfunction include an anatomic obstruction that prevents ventricular filling (eg, pulmonary venous obstruction), a primary reduction in ventricular compliance (eg, cardiomyopathy, transplant rejection), external constraints (eg, pericardial effusion), and poor hemodynamics after the Fontan procedure (eg, elevated pulmonary vascular resistance). (medscape.com)
  • This will leads to a reduction of cardiac output, stroke volume, and ventricular functioning. (syndromespedia.com)
  • we conclude that, compared with warfarin pretreatment, the relative down-regulation of PAR-1 and PAR-2 in rivaroxaban pretreatment ​​may be involved in the mechanism of reduction in bleeding complications. (researcherslinks.com)
  • A 'stroke' is a suddenly developing focal neurological deficit resulting from a cerebrovascular accident. (vin.com)
  • Cerebrovascular disease: hypertension increases the incidence of stroke in patient with diabetes. (jbclinpharm.org)
  • In order to investigate the effect of hormone therapy on stroke risk, randomized controlled trials of cardio-and/or cerebrovascular- disease prevention in women with established heart disease have been designed. (eurekaselect.com)
  • At present, therefore, a sufficiently high risk of stroke (perhaps because of age, blood pressure, or, in particular, history of cerebrovascular disease) may be the clearest indication for antihypertensive treatment. (ox.ac.uk)
  • It inhibits bacterial growth, possibly by blocking dissociation of peptidyl tRNA from ribosomes, causing RNA-dependent protein synthesis to arrest. (medscape.com)
  • The changes in haemolymph flow rates paralleled those in previous reports on reductions in protein synthesis in the hepatopancreas during hypoxia. (silverchair.com)
  • Indeed, salt reduction is one of the most cost-effective measures to prevent cardiovascular disease (CVD) in both developed and developing countries (2). (who.int)
  • High premenopausal estrogen concentrations in women are thought to be protective against stroke and cardiovascular disease. (eurekaselect.com)
  • After menopause estrogen concentrations are depleted and in the past estrogen replacement therapy was considered as a potential protective agent against both cardiovascular disease and stroke. (eurekaselect.com)
  • It is the beginning of 2021 and internal combustion engines are not yet dead, although many people predicted their significant reduction in connection with the introduction of hybrid drive in vehicles [ 1 ]. (intechopen.com)
  • This report establishes a baseline for the CVD risk factors targeted for reduction by the initiative during 2017-2021 and highlights recent changes over time. (cdc.gov)
  • Today, it is therefore generally believed that eating lots of fiber helps prevent obesity, diabetes, and cardiovascular diseases such as stroke. (nutritionfacts.org)
  • Sedentary lifestyle often causes obesity. (syndromespedia.com)
  • It's the global epidemic that affects two in every five adults, but as obesity continues to expand waistlines worldwide, researchers at the University of South Australia are warning that harmful body fat can also increase the risk of dementia and stroke. (fabresearch.org)
  • However, we did not find conclusive evidence to link a specific obesity subtype with dementia or stroke. (fabresearch.org)
  • Instead, our study suggests the possible role of inflammation and metabolic abnormalities and how they can contribute to obesity and gray matter volume reduction. (fabresearch.org)
  • Dyslipidemia in obesity is a major cause of obesityrelated CVD. (eurekaselect.com)
  • These significant improvements in stroke outcomes are concurrent with cardiovascular risk factor control interventions. (cdc.gov)
  • Interventions to reduce population salt intake should target reduction of salt in bread in all countries. (who.int)
  • Diabetic ketoacidosis (DKA) is the most common hyperglycemic emergency and causes the greatest risk for death in patients with diabetes mellitus. (lww.com)
  • CV outcomes over a 9-year follow-up period were recorded and represented a composite of stroke, stroke death, coronary heart disease (CHD), CHD death, atherosclerotic death, and CVD death. (bvsalud.org)
  • Blood pressure, stroke, and coronary heart disease. (ox.ac.uk)
  • In prospective observational studies, a long-term difference of 5-6 mm Hg in usual DBP is associated with about 35-40% less stroke and 20-25% less coronary heart disease (CHD). (ox.ac.uk)
  • Coronary heart disease (CHD) remains one of the leading causes of death in the United States, accounting for approximately 17% of overall national health care expenditures (1). (cdc.gov)
  • al of plaque in the arteries of the heart (2) that supply the blood for Coronary heart disease (CHD) remains a leading cause of death in maintaining normal cardiac function. (cdc.gov)
  • Stroke risk, therefore, would most likely be markedly diminished by removal of the left atrial appendage. (hcplive.com)
  • BACKGROUND: It is unclear whether thoracic aortic volume (TAV) is useful for cardiovascular (CV) disease prognosis and risk assessment. (bvsalud.org)
  • Caused a reduction in stroke volume and cardiac performance stroke risk stories and to a certain extent, horror stories about anabolic steroids. (youinweb.com)
  • Although the use of hormone therapy was originally associated with a reduction in the risk of heart disease by about 50% in observational studies, the results regarding stroke have been less clear. (eurekaselect.com)
  • Additionally, a higher stroke risk was reported in the first year of treatment. (eurekaselect.com)
  • Insufficient intake of fiber-rich foods may lead to the stiffening of our arteries associated with risk of having a stroke. (nutritionfacts.org)
  • All best studies to date found that fiber appears to significantly protect against the risk of stroke. (nutritionfacts.org)
  • Notably, increasing fiber just seven grams a day was associated with a significant 7% reduction in stroke risk. (nutritionfacts.org)
  • This study suggests that rivaroxaban pretreatment causes lower risk of cerebral hemorrhage in mice than warfarin pretreatment. (researcherslinks.com)
  • In terms of CVD, in particular, obese individuals are at increased risk for heart diseases and stroke. (eurekaselect.com)
  • A recent publication updated the 1998 FRS and developed a have caused early drop-out, men with less than 1 year of follow-up new risk score that predicted an individual's cardiovascular dis- were excluded from the study's cohort (Figure 1). (cdc.gov)
  • We estimated the effects of 16 risk factors on cause- specific deaths and life expectancy in Japan. (who.int)
  • Methods and Findings: We obtained data on risk factor exposures from the National Health and Nutrition Survey and epidemiological studies, data on the number of cause-specific deaths from vital records adjusted for ill-defined codes, and data on relative risks from epidemiological studies and meta-analyses. (who.int)
  • Controlling risk factors for non-communicable diseases and association from large-scale prospective studies and meta-analyses external causes is essential for the improvement of adult health. (who.int)
  • Mediterranean Region calls for urgent public health essential for maintenance of plasma volume, acid-base action to tackle unhealthy diet (1 of the 4 key risk factors), balance, transmission of nerve impulses and normal including implementation of policies to reduce levels of cell function. (who.int)
  • In older children, congestive heart failure may be caused by left-sided obstructive disease (valvar or subvalvar aortic stenosis or coarctation), myocardial dysfunction (myocarditis or cardiomyopathy), hypertension, renal failure,[1] or, more rarely, arrhythmias or myocardial ischemia. (medscape.com)
  • Although this significant CHD reduction could well be worthwhile, its size remains indefinite for most circumstances (though beta-blockers after myocardial infarction are of substantial benefit). (ox.ac.uk)
  • Attenuation of myocardial activity by overlying soft tissue may cause false-positive results. (msdmanuals.com)
  • In cardiovascular physiology, stroke volume (SV) is the volume of blood pumped from the left ventricle per beat. (wikipedia.org)
  • Stroke volume is calculated using measurements of ventricle volumes from an echocardiogram and subtracting the volume of the blood in the ventricle at the end of a beat (called end-systolic volume) from the volume of blood just prior to the beat (called end-diastolic volume). (wikipedia.org)
  • Stroke work refers to the work, or pressure of the blood ("P") multiplied by the stroke volume. (wikipedia.org)
  • Corresponding to the oxygen uptake, women's need for blood flow does not decrease and a higher cardiac frequency makes up for their smaller stroke volume. (wikipedia.org)
  • S V I = S V B S A = ( C O / H R ) B S A = C O H R × B S A {\displaystyle SVI={SV \over BSA}={(CO/HR) \over BSA}={CO \over {HR\times BSA}}} In short, the remaining blood volume left in the left ventricle not pumped out after a systole. (wikipedia.org)
  • Dietary salt raises blood pressure, and raised blood pressure is the single biggest cause of cardiovascular death and disability, accounting for 9.4 million deaths per year worldwide (1). (who.int)
  • Mitral regurgitation (MR) is caused by the retrograde flow of blood from the left ventricle (LV) into the left atrium (LA) through the mitral valve (MV), causing a systolic murmur heard best at the apex of the heart with radiation to the left axilla. (nih.gov)
  • Candesartan causes a dose-dependent, long-lasting reduction in blood pressure. (modernpharmaye.com)
  • effective and smooth blood pressure reduction over 24 hours. (modernpharmaye.com)
  • The amount of blood the left ventricle can pump (stroke volume) is directly related to 'preload' which is based on the venous return to the heart. (healthtap.com)
  • A diuretic or calcium-channel blocker should be used with an ACE inhibitor or ARB to achieve the target reduction in blood pressure in these patient populations. (cvpharmacology.com)
  • Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. (ox.ac.uk)
  • Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure. (lookformedical.com)
  • In the urinary organ, stiffness can cause accumulation of nitrogen content in the blood and increase protein loss by increasing catabolic metabolism in the body. (syndromespedia.com)
  • It has been estimated that 10 to 15 percent of blood plasma volume reduced with bed rest 1,5 . (syndromespedia.com)
  • Disuse related inactivity causes reduction of erythropoiesis, which can decrease the red blood cells. (syndromespedia.com)
  • It targets the motor proteins that cause muscle contraction and prolongs the action of the left ventricle of the heart, which pumps blood around the body. (pharmatimes.com)
  • Rather than make the heart beat more often like current medicines, omecamtiv mercabil makes the heart muscles contract for longer, which increases the volume of blood the heart pumps with each stroke without increasing the amount of energy used. (pharmatimes.com)
  • Infarct volume, bleeding volume, immunoglobulin G leakage and blood parameters were examined. (researcherslinks.com)
  • The renin-angiotensin system (RAS) is of paramount importance, having a role in the regulatory pathway involved in the maintenance of blood pressure (BP), body fluid volume, and sodium homeostasis. (hindawi.com)
  • Conventional RAS involves the conversion of inactive angiotensinogen into angiotensin I (Ang I) in the presence of renin which is released from the kidney in response to low blood volume. (hindawi.com)
  • had a recent heart attack, stroke, tuberculosis exposure or had recently coughed up blood. (cdc.gov)
  • Disuse of respiratory organs due to a sedentary lifestyle can cause bronchial obstruction and distorted respiratory functions 1 . (syndromespedia.com)
  • The evidence for the health benefits of population-wide reduction in salt intake is strong. (who.int)
  • WHO now recommends a 30% reduction in salt intake by 2025 with an eventual target of 5 g per day for all adults worldwide and lower levels for children based on calorie intake (5). (who.int)
  • World Action on Salt and Health (WASH), a non-profit charitable organization with a mission to reduce salt intake globally, has been working with many countries around the world to help establish effective salt reduction programmes to suit the needs of that particular country to reduce salt intakes (7). (who.int)
  • However,food intake caused a significant reduction in this response. (silverchair.com)
  • High dietary fiber intake may prevent strokes. (nutritionfacts.org)
  • One would have to eat an extraordinarily healthy diet to get that much, yet these cut-off values could be considered as the minimum recommended daily intake of soluble and insoluble fiber, to prevent stroke. (nutritionfacts.org)
  • Excessive salt and sodium intake is directly related to hypertension, and its reduction is a priority of WHO. (who.int)
  • For children the recommendation with the 4 main NCDs causing 2.4 million deaths in 2025, is lower and depends on their calorie intake ( 2 ). (who.int)
  • Not only was the motor fitted inside the compressor body, but the small diameter pistons and reduced piston stroke allowed the compressor to operate at a much higher RPM. (hpacmag.com)
  • The research methodology was proposed as a mix of laboratory tests and theoretical analyses, on the basis of which it was established that while maintaining the same value of the downsizing index, despite the various permissible combinations of cylinder diameter and piston stroke changes, the cycle efficiency remains unchanged. (intechopen.com)
  • Reducing hematoma volume after ICH could help improve survival and reduce disability. (bcst.md)
  • Stroke is the third most common cause of death in women and a major cause of disability. (eurekaselect.com)
  • Moreover, stroke is a leading cause of disability, and so preventing strokes in the first place-what's called primary prevention-should therefore be a key public health priority. (nutritionfacts.org)
  • Noncommunicable diseases (NCDs), such as heart attacks and strokes, cancers, diabetes and chronic respiratory disease, account for over 63% of deaths in the world today. (who.int)
  • Diastolic dysfunction has a major impact on symptom status, functional capacity, medical treatment, and prognosis in both systolic and diastolic heart failure (HF), irrespective of the cause. (bmj.com)
  • Nonetheless, a recent review has highlighted the disconnect between Doppler echo measurements and true diastolic properties of the left ventricle, and has questioned the prevailing assumption that HF with preserved systolic function is always caused by diastolic dysfunction. (bmj.com)
  • This can occur within or around the brain and may result in rapid cerebral dysfunction often by alteration in cerebral volume (mass effect). (vin.com)
  • Lower respiratory tract infection caused by Mycobacterium tuberculosis is not addressed in this document. (cdc.gov)
  • Men, on average, have higher stroke volumes than women due to the larger size of their hearts. (wikipedia.org)
  • Acute solvent exposure induced activation of cytochrome P4502E1 causes proximal tubular cell necrosis by oxidative stress. (cdc.gov)
  • The term stroke volume can apply to each of the two ventricles of the heart, although it usually refers to the left ventricle. (wikipedia.org)
  • Heart rate and Stroke volume are unfixed. (wikipedia.org)
  • Prolonged aerobic exercise training may also increase stroke volume, which frequently results in a lower (resting) heart rate. (wikipedia.org)
  • An increase in the volume or speed of venous return will increase preload and, through the Frank-Starling law of the heart, will increase stroke volume. (wikipedia.org)
  • The most likely causes of pediatric congestive heart failure depend on the age of the child. (medscape.com)
  • Curiously, structural heart disease is rarely a cause of congestive heart failure in the fetus, although it does occur. (medscape.com)
  • He and I are describing 2 ends of the spectrum and both cause low cardiac output: he describes a diseased, overloaded heart and I describe a normal, underloaded heart. (healthtap.com)
  • The Heart Estrogen- Progestin Replacement Study included stroke as secondary outcome. (eurekaselect.com)
  • METHODS: Writing group members were nominated by the committee chair and co-chair on the basis of their previous work in relevant topic areas and were approved by the American Heart Association Stroke Council's Scientific Statements Oversight Committee and the American Heart Association Manuscript Oversight Committee. (cdc.gov)
  • The document underwent extensive American Heart Association internal peer review, Stroke Council leadership review, and Scientific Statements Oversight Committee review before consideration and approval by the American Heart Association Science Advisory and Coordinating Committee. (cdc.gov)
  • however many countries are now starting to take action to formulate salt reduction action plans. (who.int)
  • The United Kingdom (UK) has successfully implemented a salt reduction programme ( Figure 1 ). (who.int)
  • Patients with other possible causes of systemic embolism were not included in the study. (hcplive.com)
  • They also increase peripheral resistance by causing vasoconstriction. (medscape.com)
  • AT1 and AT2 are involved in various physiological changes such as an increase in BP, volume overload, and facilitation of aldosterone release. (hindawi.com)
  • Furthermore, a 56% increased rate of death or dependency after stroke and a tendency of more fatal stroke were observed. (eurekaselect.com)
  • Strokes are the second most common cause of death worldwide. (nutritionfacts.org)
  • Methods of death from these causes compared with people without the syn- drome (3). (cdc.gov)
  • Inactivity slows VO(2) kinetics in association with a reduction of muscle oxidative capacity and repeated high-intensity running performance. (researchgate.net)
  • A variety of secondary causes of hemorrhage exist in dogs. (vin.com)
  • MUSC Health neurosurgeons Alejandro M. Spiotta, M.D., Jonathan R. Lena, M.D., and Raymond D. Turner, M.D., now offer all three minimally invasive surgical (MIS) options for evacuation of hematoma after intracerebral hemorrhage (ICH), the most deadly and debilitating form of stroke. (muschealth.org)
  • Thrombosis is an important part of the normal hemostatic response that limits hemorrhage caused by microscopic or macroscopic vascular injury. (medscape.com)
  • Low cardiac function may not be able to keep up with too much volume and the fluid backs up in places like the lung, neck, abdomen, and legs. (healthtap.com)
  • Since volume is proportional to pressure, as the piston travels upwards during the compression stroke, the resulting reduction in cylinder volume causes the vapour pressure to increase. (hpacmag.com)
  • The net changes in extravascular volume, assumed to be interstitial fluid volume, were 8.6 +/- 3.3 and 8.1 +/- 3.1 ml/kg, and 22.5 +/- 1.5 and 22.1 +/- 1.6 ml/kg in the corresponding protocols. (silverchair.com)
  • Volume kinetic analysis demonstrated extravascular fluid accumulation associated with isoflurane anesthesia similar to the calculated interstitial accumulation of 20.2 +/- 0.5 and 26.5 +/- 0.3 ml/kg in the ISOSV and ISOMV protocols, respectively. (silverchair.com)
  • Isoflurane, but not mechanical ventilation, decreased urinary excretion and increased interstitial fluid volume. (silverchair.com)
  • Stroke volume is intrinsically controlled by preload (the degree to which the ventricles are stretched prior to contracting). (wikipedia.org)
  • Promoting health policies that tackle the basic cause of unfair and avoidable human suffering provides an opportunity to achieve the MDGs. (who.int)
  • Sedentary lifestyle negatively affects the physiological system of human and produce multiple organ dysfunctions, resultant of this cause ill-health 1 . (syndromespedia.com)
  • Decrease sympathomedullary system activation can cause impaired physiological response against stimuli, whereas reduction of catecholamine secretion also causes impaired neuronal transmission 1 . (syndromespedia.com)
  • Without significant gains in poverty reduction, food security, education, women's empowerment and living conditions, most countries will not attain the health-related goals. (who.int)
  • many such patients may in fact have non-HF causes of their clinical presentations. (bmj.com)
  • Inactivity of the body can cause reduction of bodily temperature and desynchronize circadian rhythms. (syndromespedia.com)
  • An equivalent swept volume was introduced, defined by the coefficients determining changes in the cylinder diameter and the stroke of the piston. (intechopen.com)
  • For each dog, two-dimensional (2D) echocardiography was performed to assess LA diameter and volume for each phase of the LA cycle and to assess complete, passive, and active LA function. (openveterinaryjournal.com)
  • When the bleeding is substantial enough to form an excessive additional volume within the CNS, the results can be fatal. (vin.com)