• Primary amenorrhea is the failure of menses to occur by age 16 years, in the presence of normal growth and secondary sexual characteristics. (medscape.com)
  • If by age 13 menses has not occurred and the onset of puberty, such as breast development, is absent, a workup for primary amenorrhea should start. (medscape.com)
  • Secondary amenorrhea is defined as the cessation of menses sometime after menarche has occurred. (medscape.com)
  • Some authors suggest the absence of menses for 6 months constitutes amenorrhea, but the basis for this recommendation is unclear. (medscape.com)
  • Secondary amenorrhea is defined as the absence of menses for 3 consecutive months in women who have passed menarche. (mhmedical.com)
  • Secondary amenorrhoea, ceasing of menstrual cycles after menarche, is defined as the absence of menses for three months in a woman with previously normal menstruation, or six months for women with a history of oligomenorrhoea. (wikipedia.org)
  • Secondary amenorrhea is defined as the cessation of regular menses for three months or the cessation of irregular menses for six months and is caused by disruption of the HPO axis. (instituteofmotion.com)
  • When a girl has never experienced menarche and menses, she is said to be suffering from primary amenorrhoea or primary lack of menses. (gynaeonline.com)
  • When the patient has had at least one episode of spontaneous menses before the loss of her periods, she is said to suffer from secondary amenorrhoea. (gynaeonline.com)
  • Secondary amenorrhea is when you've been getting regular periods, but you stop getting your period for at least three months, or you stop your menses for six months when they were previously irregular. (whiletrue.live)
  • Secondary amenorrhea is the state of missing menses emerging after the menstrual cycles have become established. (ayushakti.com)
  • Examples of amenorrhea include constitutional delay of puberty, Turner syndrome, and Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. (wikipedia.org)
  • Constitutional delay of puberty is a diagnosis of exclusion that is made when the workup for primary amenorrhea does not reveal another cause. (wikipedia.org)
  • Although more common in boys, girls with delayed puberty present with onset of secondary sexual characteristics after the age of 14, as well as menarche after the age of 16. (wikipedia.org)
  • Primary amenorrhea refers to the total absence of periods by the age of 15 or 16 or within 5 years of the onset of puberty. (montereybayivf.com)
  • Of the two kinds of amenorrhea-primary and secondary-primary amenorrhea (which is delay of puberty or failure to begin menstruating by age sixteen) is the more complicated. (seaofchi.com)
  • Primary amenorrhea is when you haven't gotten a first period by age 15 or within five years of the first signs of puberty. (whiletrue.live)
  • However, exercise during puberty may be associated with primary amenorrhea and low peak BMD, while exercise after puberty may be associated with secondary amenorrhea and bone loss. (nih.gov)
  • A female with primary amenorrhea will have no menstrual flow with or without other signs of puberty. (pharmacymedicinedrugs.com)
  • Functional hypothalamic amenorrhea is a common, non-organic and theoretically reversible form of anovulation due to reduced hypothalamic GnRH drive. (nih.gov)
  • Most women with hypothalamic amenorrhea have a persistently low frequency of GnRH pulses. (mhmedical.com)
  • Secondary "hypothalamic" amenorrhea may be caused by stressful life events such as school examinations or leaving home. (mhmedical.com)
  • Amenorrhea can be caused by any mechanism that disrupts this hypothalamic-pituitary-ovarian axis, whether that it be by hormonal imbalance or by disruption of feedback mechanisms. (wikipedia.org)
  • Among secondary amenorrheas, hypothalamic amenorrhea (HA) is the one with no evidence of endocrine/systemic causal factors. (researchgate.net)
  • It is known as functional hypothalamic amenorrhea (FHA), and it is associated with metabolic, physical, or psychological stress (after severe dieting, heavy training, intense emotional events, or a combination of them) [4, 5] with or without body weight loss [6]. (researchgate.net)
  • Functional hypothalamic amenorrhea (FHA) is a relatively frequent disease due to the combination of metabolic, physical, or psychological stressors. (researchgate.net)
  • To investigate hypothalamic and/or pituitary abnormalities in women with poorly controlled insulin-dependent diabetes mellitus (IDDM) and secondary amenorrhea, we measured serum LH every 10 min for 24 h and for 2 additional h after the administration of exogenous GnRH in 8 women with IDDM and amenorrhea and compared these to data from 15 eumenorrheic nondiabetic women. (elsevierpure.com)
  • Amenorrhea can be due to pregnancy, anatomic defects of the outflow tract, ovarian disorders, and pituitary or hypothalamic disorders. (medscape.com)
  • Functional hypothalamic amenorrhea: An Endocrine Society clinical practice guideline. (msdmanuals.com)
  • Do I have hypothalamic amenorrhea? (eatingdisorderresources.com)
  • Home » Eating Disorder » Bulimia » Do I have hypothalamic amenorrhea? (eatingdisorderresources.com)
  • To confirm a hypothalamic amenorrhea your doctor may need to perform a GnRH stimulation test to check for hypothalamic amenorrhea. (eatingdisorderresources.com)
  • Primary amenorrhea is defined as an absence of secondary sexual characteristics by age 13 with no menarche or normal secondary sexual characteristics but no menarche by 15 years of age. (wikipedia.org)
  • Females who have not reached menarche at 14 and who have no signs of secondary sexual characteristics (thelarche or pubarche) are also considered to have primary amenorrhea. (wikipedia.org)
  • It has to be investigated using the clinical history of the patient: occurrence of menarche, menstrual cyclicity, time and modality of amenorrhea, and it has to be excluded any endocrine disease or any metabolic (i.e., diabetes) and systemic disorders. (researchgate.net)
  • However, absence of menarche and of any breast development by age 13 should prompt evaluation for primary amenorrhea. (msdmanuals.com)
  • Pregnancy is the most common cause for secondary amenorrhea in premenopausal women. (mhmedical.com)
  • In a multicenter, parallel-group, open label postmarketing dosing study consisting of three consecutive 28-day treatment cycles, 220 premenopausal women with secondary amenorrhea were randomized to receive daily conjugated estrogens therapy (0.625 mg conjugated estrogens) and Prometrium Capsules, 300 mg per day (n=113) or Prometrium Capsules, 400 mg per /day (n=107) for 10 days of each treatment cycle. (medicinenet.com)
  • During pregnancy or after menopause, you will lose your period, and this is a natural form of amenorrhea. (sharedjourney.com)
  • POI may also occur secondary to medical treatments, including chemotherapy, radiotherapy or surgery (see AMS Information Sheet Early menopause due to chemotherapy and radiotherapy ). (menopause.org.au)
  • Amenorrhea occurs permanently after menopause or after a hysterectomy (surgical removal of the uterus). (seaofchi.com)
  • First, we describe the physiological control systems that govern the normal menstrual cycle , and review the pathophysiology and management of secondary amenorrhea . (bvsalud.org)
  • This comprehensive primer reviews the primary and secondary causes of amenorrhea, and offers practical guidance on evaluation, differential diagnosis, and management. (medscape.com)
  • Although amenorrhea has multiple potential causes, ultimately, it is the result of hormonal imbalance or an anatomical abnormality. (wikipedia.org)
  • In some cases, hormonal contraception itself may be the cause of the amenorrhea. (medscape.com)
  • However, amenorrhea can occur when ovulation is normal, as occurs when genital anatomic abnormalities (eg, congenital anomalies causing outflow obstruction, intrauterine adhesions [Asherman syndrome]) prevent normal menstrual flow despite normal hormonal stimulation. (msdmanuals.com)
  • Estradiol is the key biomarker for assessing reproductive function in females, including amenorrhea, infertility, and menopausal status. (cdc.gov)
  • it is a retrospective diagnosis, usually made after 12 months of amenorrhea. (mhmedical.com)
  • HA occurs generally after severe stressed conditions/situations such as dieting, heavy training, or intense emotional events, all situations that can induce amenorrhea with or without body weight loss and HA is a secondary amenorrhea with a diagnosis of exclusion. (researchgate.net)
  • IU/L) and/or Primary or secondary amenorrhea at least for 3-6 months OR Diagnosis of low ovarian reserve defined as: AMH 20 IU/L, and/or failure of prior attempts of assisted reproductive techniques due to limited ovarian response (poor responder). (who.int)
  • Diagnosis and appropriate correction of intrauterine anomalies are considered et d'Application en Chirurgie essential in order to increase chances of conception. (who.int)
  • Secondary amenorrhea occurs after you have had a normal period for some time, but then begin to go without a period for more than three months. (sharedjourney.com)
  • Consideration of the target organs of these reproductive hormones (hypothalamus, pituitary, ovary, uterus) is helpful for identifying the disease process responsible for a patient's amenorrhea. (medscape.com)
  • In contrast to organic secondary hypogonadism due to structural, destructive, or congenital pathology, functional hypogonadism is due to functional HPT axis suppression. (medscape.com)
  • In most such men, gonadotropin levels are not elevated, [ 6 ] and hypogonadism is caused by functional HPT axis suppression in the presence of an intact HPT axis (analogous to functional amenorrhea in women). (medscape.com)
  • Primary amenorrhea is common among thin or athletic girls who do not have enough body fat to trigger estrogen and other sex hormones. (sharedjourney.com)
  • Production of male hormones - Certain ovarian tumors like theca cell tumors or Dermoid cysts can produce predominantly male hormones and cause amenorrhea. (gynaeonline.com)
  • Amenorrhea is the absence of a menstrual period in a female who has reached reproductive age. (wikipedia.org)
  • Even though patient's with MRKH have functioning ovaries, and therefore have secondary sexual characteristics, they experience primary amenorrhea since there is no functioning uterus. (wikipedia.org)
  • In male humans, testosterone plays a key role in the development of male reproductive tissues, such as the testis and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair. (cdc.gov)
  • Secondary amenorrhea may be caused by acquired anatomic reproductive tract abnormalities that interfere with menstrual function or obstruct the menstrual flow. (msdmanuals.com)
  • Amenorrhea may also be the result of strict dieting, vigorous exercise, organic illness, or anorexia nervosa. (mhmedical.com)
  • In a multicenter, randomized, double-blind, placebo-controlled clinical trial, the effects of Prometrium Capsules on secondary amenorrhea was studied in 49 estrogen-primed postmenopausal women. (medicinenet.com)
  • the cycle of gonadotropin stimulated estrogen production and cyclic endometrial changes are disrupted, and menstrual flow does not occur, resulting in anovulatory amenorrhea. (pharmacymedicinedrugs.com)
  • Il s'agissait d'une revue exhaustive de la littérature (Pubmed, Medline, cochrane library) concernant les méta-analyses, revues de la littérature et essais randomisés publiés sur le sujet et en anglais de 2003 à 2021. (bvsalud.org)
  • It is thought to contain a progesterone-like compound and is now thought to be useful in the following conditions: Amenorrhea, Dysmenorrhea, PMS, Endometriosis. (holisticonline.com)
  • What follows are three classifications of menstrual disorders (menorrhagia, dysmenorrhea, and amenorrhea) that are successfully treated with herbal formulas. (seaofchi.com)
  • There are two forms of dysmenorrhea: primary and secondary. (seaofchi.com)
  • Secondary dysmenorrhea is due to an underlying disorder such as endometriosis (a condition in which fragments of the lining of the uterus are found in other parts of the pelvic cavity), ovarian cysts, or pelvic inflammatory disease. (seaofchi.com)
  • In cases of secondary dysmenorrhea, the underlying disorder must be correct first before blood tonics can be effectively used. (seaofchi.com)
  • Individuals with a female phenotype can present with primary amenorrhea due to complete androgen insensitivity syndrome (CAIS), 5-alpha-reductase 2 deficiency, pure gonadal dysgenesis, 17β-hydroxysteroid dehydrogenase deficiency, and mixed gonadal dysgenesis. (wikipedia.org)
  • Gonadal dysgenesis and congenital reproductive tract anomalies cause primary amenorrhea. (msdmanuals.com)
  • Intrathecal infusion of opioids causes amenorrhea in most women. (mhmedical.com)
  • Secondary amenorrhea is much more common It's estimated to affect 3-5% of women at some point in their lives. (montereybayivf.com)
  • Amenorrhea affects about 10% of women worldwide. (gynaeonline.com)
  • 25IU on 2 occasions at least 1 month apart following 4-6 months of amenorrhea (where the women is not receiving any hormone therapy) 7 . (menopause.org.au)
  • We performed mutational analysis of NANOS3 in a cohort of 85 Brazilian women with familial or isolated POI, presenting with primary or secondary amenorrhea, and in ethnically-matched control women. (hindawi.com)
  • Wegner et al (1999) report a high incidence of primary ovarian failure in both prepubertal girls with NBS and adolescent and post-adolescent women with NBS, as evidenced by elevated gonadotrophin levels in both groups and primary amenorrhea and lack of secondary sexual development in the latter. (lu.se)
  • A woman is said to have amenorrhea when a menstrual period does not occur for more than three months in a row. (gynaeonline.com)
  • 25 IU on 2 occasions at least 1 month apart following 4-6 months of amenorrhea with exclusion of secondary causes of amenorrhoea. (menopause.org.au)
  • Severe changes in body weight can lead to a condition known as secondary amenorrhea, which means missing your period for three months or more. (healthline.com)
  • If you are older than 15 and haven't gotten your first period (primary amenorrhea) or you've missed a period for a few months (secondary amenorrhea), talk to your healthcare provider. (whiletrue.live)
  • Other endocrine glands like the thyroid, the pancreas and the adrenal cortex also have a role to play in causing amenorrhoea. (gynaeonline.com)