• Background: Passive training of specific locomotor muscle groups by means of neuromuscular electrical stimulation (NMES) might be better tolerated than whole body exercise in patients with severe chronic obstructive pulmonary disease (COPD). (bmj.com)
  • 1 Traditionally, exercise intolerance has been ascribed to respiratory mechanical and/or pulmonary gas exchange disturbances and their perceptual consequences which are manifest mainly as breathlessness (dyspnoea), especially on exertion. (bmj.com)
  • Little did I know that for a respiratory therapist who works in pulmonary rehab, our ability to adapt would soon be tested in new ways. (aarc.org)
  • the American Thoracic Society (ATS), American Association of Cardiac and Pulmonary Rehab (AARC), the World Health Organization (WHO), the European Respiratory Society (ERS), and the American Association of Respiratory Care (AARC). (aarc.org)
  • Dr. Hal Barron, Chief Scientific Officer and President R&D, GSK said: "We have a comprehensive portfolio of innovative respiratory medicines that are used by millions of patients worldwide who suffer from asthma and chronic obstructive pulmonary disease (COPD). (gsk.com)
  • Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease characterized by persistent respiratory symptoms and airflow limitation [ 1 ]. (hindawi.com)
  • Cardiac arrest from opioid overdoses is usually secondary to respiratory arrest. (ems1.com)
  • The overriding goal of treating an opioid overdose is to restore respiratory drive and airway reflexes, prevent respiratory and cardiac arrest and avoid causing severe opioid withdrawal [7]. (ems1.com)
  • The nervous system and cardiac tissues are particularly vulnerable to the disruption of oxidative metabolism and death is often the result of respiratory arrest. (issuu.com)
  • If the Apgar score is below 7 at the five-minute mark, some providers will check it a few minutes later to assess the effect of any action taken to correct any respiratory or cardiac concerns. (medlineplus.gov)
  • Rapid NAATs often have the ability to test for SARS-CoV-2, influenza , and respiratory syncytial virus (RSV). (medscape.com)
  • The obvious need for new treatment modalities is directed towards two lines of approach: anatomic (such as surgical procedures) and functional, i.e. electrical stimulation of the upper airway dilator muscles [ 2 , 3 ]. (ersjournals.com)
  • The genioglossus (GG) muscle, which is the main tongue protrusor, has been shown to reduce pharyngeal resistance and collapsibility by far more than other upper airway dilator muscles [ 4 , 5 ], and has become, therefore, the main target for functional stimulation for therapeutic purposes [ 2 , 3 ]. (ersjournals.com)
  • When overstimulated, opioid receptors desensitize the brainstem to rises in carbon dioxide, which causes respiratory depression, loss of protective airway reflexes and respiratory arrest. (ems1.com)
  • Hypoglossal nerve stimulation is a treatment for obstructive sleep apnea that uses an implant to stimulate a nerve under the tongue to prevent the tongue from blocking the airway. (hopkinsmedicine.org)
  • Hypoglossal nerve stimulation aims to improve breathing, treat upper airway obstruction and reduce snoring, gasping and choking so the person can have a more restful sleep. (hopkinsmedicine.org)
  • A typical decrementing response to repetitive nerve stimulation in myasthenia gravis. (medscape.com)
  • Eighteen patients (in 7 high facility hospitals) with severe respiratory failure received a low- and high-rate repetitive nerve stimulation test, and negative inspiratory pressure was measured. (nih.gov)
  • Repetitive nerve stimulation test showed no response in the most severe stage. (nih.gov)
  • Emerging evidence from the Galaxy collaboration programme will provide new insights into the pathophysiological features of respiratory diseases and disease progression risk factors. (gsk.com)
  • In 2017, 3.91 million all-age deaths worldwide were due to chronic respiratory diseases, including 3.19 million deaths from COPD [ 4 ]. (hindawi.com)
  • Identification of parameters that improve the response to functional stimulation of the tongue may help in selecting patients most appropriate for this approach as a treatment modality. (ersjournals.com)
  • Knee extensor strength and endurance, whole body exercise capacity, and health related quality of life (Chronic Respiratory Disease Questionnaire, CRDQ) were assessed. (bmj.com)
  • Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure from high spinal cord injuries should only be used with special arrangements for clinical governance, consent, and audit or research. (bvsalud.org)
  • Based on what we saw in the past, we anticipated they would have some form of interstitial lung disease related to Acute Respiratory Distress Syndrome (ARDS). (aarc.org)
  • Minimise stimulation and handling as this can worsen respiratory distress. (lortsmith.com)
  • Paralysis of the respiratory muscles in people with tetraplegia affects their ability to breathe and contributes to respiratory complications. (iospress.com)
  • It consists of a cholinergic syndrome of excess respiratory and oral secretions, diarrhea and vomiting, diaphoresis, convulsions, altered mental status, miosis, bradycardia, and generalized weakness that can progress to paralysis, respiratory arrest and death (1-3). (cdc.gov)
  • depression manifests as impaired gait, dizziness, and coma, possibly progressing to respiratory paralysis and death. (issuu.com)
  • Accordingly, the present study was designed to compare the effect of electrical stimulation of the anterior versus the posterior parts of the tongue on pharyngeal stability and size in OSA patients. (ersjournals.com)
  • In addition, we evaluated the relationship between individual relevant cephalometric characteristics of our patients and the response to electrical stimulation of the GG. (ersjournals.com)
  • Due to benzoctamine's ability to tranquilize without causing respiratory depression, scientists are moving forward with studies that test its sedative effects in patients with respiratory failure. (wikipedia.org)
  • There are usually many risks associated with using sedatives on patients who are suffering from respiratory failure, which has made it difficult to administer tranquillizing medications in situations when they are desirable. (wikipedia.org)
  • The US Centers for Disease Control and Prevention also provides recommendations for the management of patients with acute upper respiratory illness. (medscape.com)
  • Conclusions: For severely disabled COPD patients with incapacitating dyspnoea, short term electrical stimulation of selected lower limb muscles involved in ambulation can improve muscle strength and endurance, whole body exercise tolerance, and breathlessness during activities of daily living. (bmj.com)
  • We therefore propose that passive stimulation of locomotor muscle groups by neuromuscular electrical stimulation (NMES) may provide an alternative approach for improving physical capacity in severely compromised patients with COPD who present with incapacitating dyspnoea. (bmj.com)
  • Hypothesis Cingulate stimulation would increase patients' hot pain thresholds if non-stimulation 70-150 Hz activity encoded psychophysical pain responses. (medrxiv.org)
  • Two patients had a higher pain threshold with stimulation than without, while the other two patients had no difference. (medrxiv.org)
  • We found that patients who responded to stimulation had specific time windows where high-frequency activity was associated with increased pain ratings. (medrxiv.org)
  • Within 1-65 h after exposure, 18 of the patients with severe respiratory failure had become ill. (nih.gov)
  • The system dependably recognised spontaneous respiratory effort, stimulating appropriately, and was well tolerated by patients. (iospress.com)
  • The automatic stimulation system augmented spontaneous breathing and coughing in tetraplegic patients and may provide a potential means of respiratory support for tetraplegic patients with reduced respiratory capacity. (iospress.com)
  • Patients receiving narcotic analgesics for acute pain control require careful monitoring for adverse effects of these agents: constipation, urinary retention, and respiratory depression. (medscape.com)
  • A hypoglossal nerve stimulation implant is an alternative for patients who cannot tolerate CPAP treatment. (hopkinsmedicine.org)
  • May be associated with convulsions followed by coma and respiratory arrest. (nih.gov)
  • Earlier data demonstrate that populational Zn status is associated with the prevalence of respiratory tract infections in children and adults ( 6 , 7 ). (spandidos-publications.com)
  • Infants hospitalised with acute respiratory tract infections. (lu.se)
  • The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in December 2019. (aarc.org)
  • GSK is at the forefront of biologics respiratory research, using targeted approaches to improve the management of a range of respiratory disease sub-types. (gsk.com)
  • Individuals with severe coronavirus disease 2019 (COVID-19) may present respiratory and motor complications, requiring rehabilitation programs (RP) for long periods. (bvsalud.org)
  • Marketed as Tacitin by Ciba-Geigy, it is different from most sedative drugs because in most clinical trials it does not produce respiratory depression, but actually stimulates the respiratory system. (wikipedia.org)
  • However, when co-administered with other drugs that cause respiratory depression, like morphine, it can cause increased respiratory depression. (wikipedia.org)
  • While these studies point to higher doses of benzoctamine being needed to exert the same pharmacological effects, the drug is still popular because of its ability to act as an anxiolytic without producing the common respiratory depression associated with other sedative drugs. (wikipedia.org)
  • Opioid toxicity should be suspected when CNS depression, respiratory depression, and pupillary constriction are present [3]. (ems1.com)
  • The first step is to evaluate the extent of the patient's respiratory depression. (ems1.com)
  • CNS stimulation may precede CNS depression. (issuu.com)
  • Of these, 42 developed respiratory failure, and 25 of those who developed respiratory failure were referred to 9 high facility hospitals for treatment of severe respiratory failure and autonomic nervous system involvement. (nih.gov)
  • In certain cases, excessive autonomic activity from stimulation of nicotinic receptors will predominate in the syndrome and will manifest as fasciculations, hypertension, mydriasis, and tachycardia. (cdc.gov)
  • In the present study, we compared the response to GG electrical stimulation at the anterior area (GGa-ES), which activates the whole GG and the posterior area (GGp-ES), which activates preferentially the longitudinal fibres. (ersjournals.com)
  • Effect of brain stem transections on respiratory responses to electrical stimulation of the medulla oblongata. (tau.ac.il)
  • We used these results to determine the individual's thermal pain threshold with and without electrical stimulation. (medrxiv.org)
  • Surface functional electrical stimulation (FES) of abdominal wall muscles can be used to increase tidal volume (VT) and improve cough peak flow (CPF) in tet raplegic subjects who are able to breathe spontaneously. (iospress.com)
  • [ 148 ] Nonpharmacologic pain-relieving modalities such as moist hot packs and transcutaneous electrical nerve stimulation should also be considered. (medscape.com)
  • Cite this: Upper Respiratory Infections: Viral Testing in Primary Care - Medscape - Oct 23, 2023. (medscape.com)
  • Adherence reaction mediated through the CR receptors on phagocytes lead to stimulation of phagocytosis, activation of metabolism and secretory function and movement of phagocytes into the inflammatory site. (dadamo.com)
  • The second group of receptors reacts with small complement fragments (C4a, C3a, C5a) as well as with C1q, Ba, Bb and factor H. Stimulation of these receptors results in various biological effects (chemotaxis, secretion of vasoactive amines, mediators of the inflammatory and anaphylactic reaction etc. (dadamo.com)
  • Stimulation of these receptors generally results in euphoria, decreased perception of pain and drowsiness. (ems1.com)
  • Select when the contaminant and concentration of the contaminant are known and the respiratory protection criteria factors for using Air Purifying Respirators (APR) or Powered Air Purifying Respirators (PAPR) are met. (cdc.gov)
  • Stimulation of these muscles during sleep is an evolving treatment approach for obstructive sleep apnea. (hopkinsmedicine.org)
  • Chronic stimulation of the hypoglossus nerve may provide a new treatment modality for obstructive sleep apnoea (OSA). (ersjournals.com)
  • Hypoglossal nerve stimulation with an implanted device can help some people manage obstructive sleep apnea without a continuous positive airwave pressure (CPAP) machine. (hopkinsmedicine.org)
  • What is hypoglossal nerve stimulation? (hopkinsmedicine.org)
  • A hypoglossal nerve stimulation device sends a gentle electric pulse to a branch of the hypoglossal nerve. (hopkinsmedicine.org)
  • If you and your doctor think you may be a candidate for hypoglossal nerve stimulation, the next step is a drug-induced sleep endoscopy. (hopkinsmedicine.org)
  • Movement activity, heart rate, respiratory rate, axillary temperature and blood-oxygen saturation were calculated separately for ON and OFF. (nih.gov)
  • Infants maintained body temperature and arterial-blood oxygen level independent of stimulation condition. (nih.gov)
  • Com- paring the epidemiology of this strain in Australia to the epidemiology of its well-documented spread in Europe Characteristics of Traveler will provide valuable insights into RHDV epidemiology with Middle East Respiratory relevant to both continents. (cdc.gov)
  • To examine the therapeutic potential of stochastic vibrotactile stimulation (SVS) as a complementary non-pharmacological intervention for withdrawal in opioid-exposed newborns. (nih.gov)
  • Respiratory Inhaled hydrogen sulfide initially affects the nose and throat. (issuu.com)
  • Mapping, description, and evaluation of physiotherapy treatment methods including frequent changes in body position and stimulation of physical activity. (lu.se)
  • This study aims to evaluate the feasibility and effectiveness of a novel abdominal FES system which generates stimulation automatically, synchronised with the subjects' voluntary breathing activity. (iospress.com)
  • The increase in the heart respiratory chain proteome suggests an increase in mitochondrial oxidative capacity, which could compensate for the energy deficit caused by the inhibition of glycolysis. (nature.com)
  • We hypothesised that both individual patient-characteristics and the mechanical function of the area of the GG where stimulation was applied may be responsible for these differences. (ersjournals.com)
  • The data presented at ATS demonstrate the breadth of activities being undertaken by GSK to improve patient outcomes and generate evidence that will help answer some of the key questions in respiratory medicine. (gsk.com)
  • The patient was noted to be somnolent upon arrival to the ED, but responded to stimulation and was maintaining normal oxygenation on room air. (medscape.com)
  • Low concentrations (50 ppb) can rapidly produce irritation of the nose, throat, and lower respiratory tract. (issuu.com)
  • citation needed] While it is a relatively new anti-anxiety drug,[clarification needed] its popularity is increasing as a result of it being able to have comparable anxiolytic and sedative effects to other medications without their potentially fatal respiratory depressive side effects. (wikipedia.org)
  • Negative physiological and psychological effects on athletes have been reported, such as respiratory issues and increased stress. (frontiersin.org)
  • The above-described effects can lead to asphyxia from upper respiratory tract obstruction. (dentalcare.com)
  • Improved Zn status may also reduce the risk of bacterial co‑infection by improving mucociliary clearance and barrier function of the respiratory epithelium, as well as direct antibacterial effects against S. pneumoniae. (spandidos-publications.com)
  • We conclude that directing stimulation to longitudinal fibres of the GG improves the flow-mechanical effect. (ersjournals.com)
  • Accordingly, directing stimulation to the protrusive part of the GG is likely to improve the flow-mechanical response. (ersjournals.com)
  • Conclusion Stimulation of cingulate regions with increased pain-related neural activity was more effective at modulating pain perception than stimulating non-responsive areas. (medrxiv.org)
  • Personalized evaluation of neural activity biomarkers could help identify the best target for stimulation and predict its effectiveness in future studies evaluating DBS. (medrxiv.org)
  • Friedrich Jolly coined the term myasthenia gravis pseudoparalytica in 1895 and also pioneered one of the assessment methods, repetitive stimulation, which is discussed later. (medscape.com)
  • Some studies have even shown that it stimulates the respiratory system. (wikipedia.org)
  • The automatic stimulation system ensured that consistent stimulation was achieved. (iospress.com)
  • Respiratory rate during quiet breathing decreased in all subjects when stimulated, whereas minute ventilation increased by 1.05-2.07 L/min. (iospress.com)
  • In previous studies we observed large differences in response to stimulation of the genioglossus (GG). (ersjournals.com)
  • We compared spirometry during unassisted and FES-assisted quiet breathing and coughing, and measured the effect of stimulation on end-tidal CO2 (EtCO2) during quiet breathing. (iospress.com)
  • Blood pressure and respiratory changes by stimulation of brain septal area in rats. (bvsalud.org)