• Processes involved in atherosclerosis include coagulation, inflammation, lipid metabolism, intimal injury, and smooth muscle cell proliferation (see the image below). (medscape.com)
  • Other factors, such as chronic systemic inflammation that has been tightly linked to accelerated atherosclerosis partially explain the increased CV risk. (bmj.com)
  • Atherosclerosis is a disease characterized by chronic inflammation and fibrosis of the intima of large and medium sized arteries. (lu.se)
  • In this work, recently published in the journal ACS Nano ( 'A Comparative Study of Ultrasmall Calcium Carbonate Nanoparticles for Targeting and Imaging Atherosclerotic Plaque' ), the team compared various nanoparticles specifically designed for different features of atherosclerosis (such as calcification or inflammation), which provide useful information about the phase or stage of plaque development. (nanowerk.com)
  • Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis. (bvsalud.org)
  • Pigs on a severely copper-deficient diet showed weakened and ruptured arteries (aneurysms), while moderately deficient pigs "survived with scarred vessels but demonstrated a tendency toward premature atherosclerosis" including foam cell accumulation ( 2 ). (blogspot.com)
  • In the current review, we analysed automatic detection methods for the diagnosis of CAD, MI and carotid atherosclerosis based on thoracic and Intravascular Ultrasound (IVUS). (shu.ac.uk)
  • But for MI and carotid atherosclerosis IVUS is still in the experimental stage. (shu.ac.uk)
  • Aim To investigate the usefulness of carotid atherosclerosis assessment in cardiovascular risk stratification of patients with psoriatic disease compared with the Framingham Risk Score (FRS). (bmj.com)
  • Reduces the development of subclinical atherosclerosis and slows progression as time since cessation lengthens. (cdc.gov)
  • Conclusions Ultrasound assessment of subclinical atherosclerosis may improve risk stratification of patients with psoriatic disease, particularly of those with PsA. (bmj.com)
  • The term atherosclerosis is derived from the Greek "athero," meaning gruel, or wax, corresponding to the necrotic core area at the base of the atherosclerotic plaque, and "sclerosis" for hardening, or induration, referring to the fibrous cap of the plaque's luminal edge. (medscape.com)
  • The etiology of atherosclerosis is unknown, but there are multiple factors that contribute to atherosclerotic plaque progression. (medscape.com)
  • Patients were stratified into three ultrasound-based risk categories (low, intermediate and high) according to the severity of atherosclerosis. (bmj.com)
  • A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. (wikipedia.org)
  • Atherosclerosis is a disease of the arteries in which fatty material is deposited in the vessel wall, resulting in narrowing and eventual impairment of blood flow. (adam.com)
  • Nanowerk News ) Atherosclerosis is characterized by the hardening of blood vessels, especially certain arteries, due to the local buildup of fibers and lipids (mainly cholesterol) in the inner wall of an artery, causing it to narrow. (nanowerk.com)
  • Atherosclerosis is a condition in which patchy deposits of fatty material (atheromas or atherosclerotic plaques) develop in the walls of medium-sized and large arteries, leading to reduced or blocked blood flow. (msdmanuals.com)
  • Atherosclerosis is caused by repeated injury to the walls of arteries. (msdmanuals.com)
  • Atherosclerosis can affect the medium-sized and large arteries of the brain, heart, kidneys, other vital organs, and legs. (msdmanuals.com)
  • Tissue plasminogen activator (tPA) is considered for treatment of a patient who arrives in the emergency department following onset of symptoms of myocardial infarction. (proprofs.com)
  • A patient arrives in the emergency department with symptoms of myocardial infarction, progressing to cardiogenic shock. (proprofs.com)
  • Atherosclerosis shows no symptoms until a complication occurs. (adam.com)
  • An increase of IMT is usually the first sign of atherosclerosis, before we even develop symptoms and is therefore an important instrument for early detection and the study of prevention. (lu.se)
  • SST2 PET /MRI was generally consistent with 18F-fluorodeoxyglucose PET /computed tomography imaging in LVV patients with contemporaneous clinical scans but with very low background signal in the brain and heart , allowing for unimpeded assessment of nearby coronary, myocardial, and intracranial artery involvement. (bvsalud.org)
  • ABSTRACT Hyperhomocysteinaemia is considered as an important independent risk factor for atherosclerosis and thrombotic disease. (who.int)
  • Iron accumulation can affect older people through atherosclerosis that can lead to vascular disease and neurological disease such as Alzheimer's and Parkinson's. (northwestern.edu)
  • This large international study in 20,000 individuals finds the annual rate for myocardial infarction was low 0.6% but that combination therapy increased the risk 26% per year. (natap.org)
  • In addition, the relative increase in the risk of myocardial infarction per year cannot be extrapolated beyond the duration of follow-up in the study…… …….the annual rate of myocardial infarction, even among those exposed to therapy for four to six years, was less than 0.6 percent, and only a portion of the apparent excess risk could be attributed to combination antiretroviral therapy. (natap.org)
  • Other known risk factors for myocardial infarction probably contributed to the occurrence of these events. (natap.org)
  • Hence, the substantial benefits of combination antiretroviral therapy continue clearly to outweigh the increased risk of myocardial infarction associated with this therapy. (natap.org)
  • Conversely, significant contributions from diabetes, hypertension, and lipodystrophy were not identified…… we found no evidence to suggest that the duration of HIV-1 infection, the level of prior immunodeficiency, or the degree of HIV-1 RNA replication affected the association between exposure to therapy and the risk of myocardial infarction. (natap.org)
  • Atherosclerosis and the risk factors 14. (muni.cz)
  • The presence of preclinical atherosclerosis increases global cardiovascular risk - preclinical atherosclerosis can be considered an emerging determinant in assessing global cardiovascular risk. (escardio.org)
  • Independent markers of multifocal atherosclerosis -directly associated with an increased risk of CV events- are intima-media thickness, reduced ankle-brachial pressure index and impaired flow-mediated dilatation. (escardio.org)
  • Risk factors for atherosclerosis alone aren't accurate enough in predicting cardiovascular disease in adults with no history of atherosclerosis disease. (escardio.org)
  • The presence of one or more risk factors for atherosclerosis (ATS) is associated with the development of cardiovascular disease (CVD). (escardio.org)
  • The way we eat, how much we exercise, and whether we smoke tobacco or drink alcohol, among others are some of the main risk factors for both atherosclerosis and cardiovascular disease. (lu.se)
  • This means that these risk factors can be modified and therefore we can have an active role in reducing our risk for developing atherosclerosis and other cardiovascular diseases. (lu.se)
  • Further advancements in the treatment of atherosclerosis requires a better understanding of the molecular disease mechanisms and development of interventions more specifically targeted towards these mechanisms. (lu.se)
  • The development of atherosclerosis is complicated, but the primary event seems to be repeated, subtle injury to the artery's inner lining (endothelium), through various mechanisms. (msdmanuals.com)
  • Atherosclerosis, the most common type, means hardening related to plaques, which are deposits of fatty materials. (msdmanuals.com)
  • Atherosclerosis is a progressive condition that starts during our childhood by accumulating fatty materials in the interior of our blood vessels. (lu.se)
  • Since this time, a number of papers have been published on the relationship between copper intake and cardiovascular disease in animals, including several showing that copper supplementation prevents atherosclerosis in one of the most commonly used animal models of cardiovascular disease ( 6 , 7 , 8 ). (blogspot.com)
  • According to the current paradigm, atherosclerosis is not a bland cholesterol storage disease, as previously thought, but a dynamic, chronic, inflammatory condition due to a response to endothelial injury. (medscape.com)
  • Through the network analysis, reduction of cardiac preload and myocardial contractility was shown to be the major effect of Schisandra components, which was further experimentally validated. (frontiersin.org)
  • HupA significantly diminished the infarct size and inhibited the activities of myocardial enzymes, including creatine kinase (CK), the MB isoenzyme of creatine kinase (CK-MB), lactate dehydrogenase (LDH) and cardiac troponin T (cTnT). (spandidos-publications.com)
  • Priscilla DH and Prince PS: Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. (spandidos-publications.com)
  • Myocardial deformation imaging by 2D speckle tracking echocardiography for assessment of diastolic dysfunction in murine cardiopathology. (otago.ac.nz)
  • In addition, the expression of NCOR2 and NFAT in myocyte were experimentally confirmed to be associated with Schisandra in the treatment of AMI, which may be responsible for the preservation effect of myocardial contractility. (frontiersin.org)
  • Given the excellent security profile of vinpocetine this study suggests vinpocetine may be a restorative candidate for treating atherosclerosis Oil-red O staining as explained previously [15]. (biomasswars.com)
  • Taken collectively our data reveal a novel part of vinpocetine in reduction of pathogenesis of atherosclerosis at least partially through suppressing LOX-1 signaling pathway. (biomasswars.com)
  • Our results demonstrate the potential of this simple yet groundbreaking nanoprobe, which could inspire new designs of contrast agents for atherosclerosis and other types of diseases, and offer the possibility of formulating new theranostic agents (that can be used for therapeutic as well as diagnostic purposes)," they concluded. (nanowerk.com)