• Antithyroid Drug-Induced Agranulocytosis: Is Routine White Blood Cell Count Effective for the Detection? (jamanetwork.com)
  • We appreciate and agree with the comment by Asawa et al that "the leukocyte differentiated count, not only routine white blood cell count is critically important for the correct diagnosis of antithyroid drug-induced agranulocytosis in some cases. (jamanetwork.com)
  • From 1975 to 1990, 72 patients presented with antithyroid drug-induced agranulocytosis. (jamanetwork.com)
  • Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. (wikipedia.org)
  • citation needed] The terms agranulocytosis, granulocytopenia and neutropenia are sometimes used interchangeably. (wikipedia.org)
  • To be precise, neutropenia is the term normally used to describe absolute neutrophil counts (ANCs) of less than 500 cells per microlitre, whereas agranulocytosis is reserved for cases with ANCs of less than 100 cells per microlitre. (wikipedia.org)
  • And yes, this will appear very similar to a neutropenia because agranulocytosis is a blood disorder in which the body is unable to make neutrophils. (coastdental.com)
  • for these reasons, granulocytopenia is a more etymologically consistent term, and as such, is sometimes preferred to "agranulocytosis" (which can be misinterpreted as "agranulocyt-osis", meaning proliferation of agranulocytes (i.e. lymphocytes and monocytes). (wikipedia.org)
  • Agranulocytosis implies a more severe deficiency than granulocytopenia. (wikipedia.org)
  • Severe albumin, inborn achieves agranulocytosis backslab crease. (rusf.ru)
  • Acquired agranulocytosis is a rare, drug-induced blood disorder that is characterized by a severe reduction in the number of white blood cells (granulocytes) in the circulating blood. (checkorphan.org)
  • Although the reaction is generally idiosyncratic rather than proportional, experts recommend that patients using these drugs be told about the symptoms of agranulocytosis-related infection, such as a sore throat and a fever. (wikipedia.org)
  • We report a case of ritodrine hydrochloride-induced agranulocytosis accompanied by bacteremia due to catheter infection. (hindawi.com)
  • Vulnerability to infection is extremely high in patients with agranulocytosis, which is the virtual absence of neutrophils in peripheral blood, with ANC typically lower than 100/μL. (medscape.com)
  • So if an individual has Infantile Genetic Agranulocytosis, these are individuals who absolutely are going to be prone to infection and periodontitis, of course, is no exception. (coastdental.com)
  • Individuals with agranulocytosis must be very careful to avoid infection. (coastdental.com)
  • It absolutely means that individuals who may be experiencing oral infection associated with their Infantile Genetic Agranulocytosis are individuals who must be treated right away and then maintained consistently in order to continue to reduce the threat or vulnerability that they have to infection. (coastdental.com)
  • In agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils, and eosinophils) drops below 200 cells/mm3 of blood. (wikipedia.org)
  • Agranulocytosis refers to a situation where the absolute neutrophil count (ANC) falls to less than 100 neutrophils per microliter of blood. (radiopaedia.org)
  • In using VASOTEC consideration should be given to the fact that another angiotensin converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that VASOTEC does not have a similar risk (see WARNINGS ). (rxlist.com)
  • No patients discontinued treatment due to agranulocytosis. (psychiatrist.com)
  • citation needed] The Centers for Disease Control and Prevention traced outbreaks of agranulocytosis among cocaine users, in the US and Canada between March 2008 and November 2009, to the presence of levamisole in the drug supply. (wikipedia.org)
  • To formally diagnose agranulocytosis, other pathologies with a similar presentation must be excluded, such as aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia and leukemias. (wikipedia.org)
  • The findings indicate that there was no agranulocytosis or hepatic toxicity suggesting that AQ may pose no public health risk in its wide therapeutic dosage uses. (bvsalud.org)
  • Agranulocytosis may be asymptomatic, or may clinically present with sudden fever, rigors and sore throat. (wikipedia.org)
  • If you are having treatment or taking medicine that could cause agranulocytosis, your health care provider will use blood tests to monitor you. (medlineplus.gov)
  • Despite this, "agranulocytosis" remains the most widely used term for the condition. (wikipedia.org)
  • So we're talking about Infantile Genetic Agranulocytosis and this, for our listeners, is going to sound relatively similar to the previous episode where we talked about neutropenias. (coastdental.com)
  • You see, an individual who has Infantile Genetic Agranulocytosis is an individual who is born, present at birth with this congenital or genetic disorder. (coastdental.com)
  • You can also have Acquired Agranulocytosis in which an individual could be exposed to chemicals, some prescription medications, cancer medications, antipsychotic medications, for example, that will develop a form of Drug-Induced Agranulocytosis. (coastdental.com)
  • Ritodrine hydrochloride is used for preterm labor, although serious side effects, including agranulocytosis, are reported. (hindawi.com)