• Also used to document insulin resistance, especially in horses suspected of pituitary adenoma. (tamu.edu)
  • Despite in vitro and in vivo studies have demonstrated a direct action of pegvisomant on different organs and tissues [35] and a possibile direct role in MCC950 cost chemoresistance [36, 37], data concerning Selleck EPZ5676 direct effects of PEGV on GH secretion by pituitary adenoma are conflicting. (src-signal.com)
  • Different patterns of malignant change occur in pleomorphic adenoma , of which true malignant mixed tumor (carcinosarcoma) is one form. (medscape.com)
  • The other 2 forms are carcinoma ex pleomorphic adenoma and metastasizing benign pleomorphic adenoma . (medscape.com)
  • Many of the patients had a history of pleomorphic adenoma, recurrent pleomorphic adenoma, or recurrent carcinoma ex pleomorphic adenoma. (medscape.com)
  • A history of exposure to irradiation of pleomorphic adenoma has been reported. (medscape.com)
  • Despite its low incidence, basal cell adenoma is the third most common benign tumor of the salivary gland after pleomorphic adenoma and Warthin's tumor. (e-acfs.org)
  • BCA is histologically similar to other tumors, such as pleomorphic adenoma, Warthin's tumor, and basal cell adenocarcinoma (BCAC). (e-acfs.org)
  • She was diagnosed with pleomorphic adenoma based on fine needle biopsy, and superficial parotidectomy was recommended, but the patient was lost to follow-up. (e-acfs.org)
  • Patients Twenty patients with primary hyperparathyroidism were referred to our clinic, underwent surgical neck exploration or mediastinotomy and were diagnosed as having parathyroid adenoma. (go.jp)
  • Results 99m Tc-tetrofosmin imaging demonstrated focal uptake in 19 out of 20 patients with parathyroid adenoma. (go.jp)
  • The pathway from embryogenesis to the full differentiation of specific functional cell types within the pituitary is controlled by numerous genes that encode transcription factors. (medscape.com)
  • Hereditary factors such as mutations in BRCA and KRAS genes, hormone levels such as androgens and gonadotrophins, and cytokines have been shown to increase ovarian cancer risk. (biomedres.us)
  • Monogenic diabetes is commonly caused by single-gene mutations with more than 50 causative genes identified. (pfmjournal.org)
  • The genetic factors underlying vitamin D deficiency in Korea included polymorphisms in the GC, PDE3B , NADSYN1 , and ACTE1P genes. (e-enm.org)
  • Thyrotropin receptor and thyroid transcription factor-1 genes variant in Chinese children with congenital hypothyroidism. (tsh-receptor-mutation-database.org)
  • Basal cell adenoma of the salivary glands is a rare, benign disease accounting for 1% to 3% of salivary gland tumors. (e-acfs.org)
  • However, accumulation of genetic mutations could be a factor. (medscape.com)
  • There is a kind of zeitgeist that findings in genetics, namely somatic mutations, are reflexively viewed as being causative for carcinogenesis, although some 80% of all cancers are presently termed "sporadic" (i.e., with no proven cause). (4open-sciences.org)
  • The observation that one inch of cancerous liver tissue can have more than 100 000 000 mutations and an identical mutation can result in different phenotypes, depending on the environment surrounding that mutation, makes it very unlikely that mutations by themselves are causative of most cancers. (4open-sciences.org)
  • Some of the causes of single nodule include: cancerous tumor, solid benign tumor (adenoma), and benign tumor filled with fluid (cyst). (newhealthguide.org)
  • Nonpuerperal hyperprolactinemia is a state in which pituitary lactotroph adenomas produce prolactin. (medscape.com)
  • Prolactin production can be stimulated by the hypothalamic peptides, thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP), epidermal growth factor, and dopamine receptor agonists. (medscape.com)
  • These lactotroph adenomas are called prolactinomas and account for approximately 40% of all pituitary tumors. (medscape.com)
  • Consider discontinuing RISPERDAL ® if a clinically significant decline in WBC occurs in the absence of other causative factors. (nih.gov)
  • Takashima K, Ito Y, Gonzalez FJ, Nakajima T. Different mechanisms of DEHP-induced hepatocellular adenoma tumorigenesis in wild-type and Ppar alpha-null mice. (who.int)
  • The convergence hypothesis maintains that multiclonal stem cells of the epithelial and mesenchymal components play a causative role. (medscape.com)
  • Measurement of insulin like growth factor 1 hormone (IGF-1). (tamu.edu)
  • Detection of antibodies to Histoplasma capsulatum, the causative agent of histoplasmosis, by complement fixation. (tamu.edu)
  • Detection of Heterobilharzia americana, the causative agent of canine schistosomiasis, by PCR. (tamu.edu)
  • Inflammation leads to excessive uptake of calcium by cells, and is a factor in obesity, depression, and the degenerative diseases. (raypeat.com)
  • Here we summarize several noteworthy biological factors and environmental exposures that are postulated to be responsible culprits. (wjgnet.com)
  • The purpose of this review is to summarize epidemiological factors that contribute to the ovarian cancer risk. (biomedres.us)
  • This review discusses relevant primary research articles, reviews, cohort studies, population- based studies, pooled data and meta-analysis on ovarian cancer epidemiology and summarizing the positive and negative risk factors for ovarian cancer development. (biomedres.us)
  • Epidemiologic factors were discussed under five subheadings including hereditary factors, cancer stem cells, hormonal influences, environmental factors, and lifestyle choices. (biomedres.us)
  • Although the association between general obesity or body mass index and the ovarian cancer risk is inconclusive, central obesity could be a risk factor for ovarian cancer. (biomedres.us)
  • Some of the risk factors for ovarian cancer are sub-type specific and further studies are required to completely understand its complex etiology. (biomedres.us)
  • Although some reviews are available on this topic, this review is comprehensive and provides novelty as it includes the role of cancer stem cells in ovarian cancer development in addition to other risk factors. (biomedres.us)
  • We cannot rule out the possibility that the breast cancer developed due to the effect of the slight elevation of estrogen over a long period of time, but the actual causative factors in this patient were unable to be definitively identified. (biomedcentral.com)
  • Risk factors are said to be genetic factors and hormonal abnormalities due to obesity or testicular diseases. (biomedcentral.com)
  • Although still poorly defined, it has been linked to diverse factors, including distracted physicians, noncompliant patients, and intrinsic features of the adenoma itself [44]. (src-signal.com)
  • In both cases, the mass was completely excised, postoperative pathology reports confirmed the diagnosis of basal cell adenoma. (e-acfs.org)
  • The principal pathology, indication for MRI as well as the factor of this exploration in order to examination of fistula within ano had been analysed. (camkkinases.com)
  • A negative feedback loop occurs such that the hormones produced in the target glands feed back to inhibit the release of their respective regulatory pituitary and hypothalamic factors. (medscape.com)
  • Genetic factors influencing vitamin D deficiency in humans have been studied in Europe but are less known in East Asian countries, including Korea. (e-enm.org)
  • We aimed to investigate the genetic factors related to vitamin D levels in Korean people using a genome-wide association study (GWAS). (e-enm.org)
  • Prolonged antibiotic therapy is suggested due to the frequent finding of UTI as an associated or causative factor. (wikipedia.org)
  • Overweight/obesity and change in weight or BMI do not correlate with fracture risk in postmenopausal women, but an increase in weight is the protective factor against incident fractures in normal-weight participants. (bvsalud.org)
  • The researchers mentioned that, unlike genetic predisposition, diet, vices, and overweight are risk factors that can be controlled to prevent the degeneration of renal function. (blimpt.com)
  • Identifying risk factors for EOCRC is the first step in mitigating the rising burden of this disease. (wjgnet.com)
  • For pituitary adenomas, transsphenoidal surgery is usually considered the first line of treatment, followed by medical therapy for residual disease. (medscape.com)
  • Challenges faced when implementing precision medicine in diabetes are disease heterogeneity, various genetic influences, difficulties of accurate diagnosis, limitations of current treatment, and social, environmental, and psychological factors [ 6 ]. (pfmjournal.org)
  • Symptoms and signs of the causative disorder may also be present. (msdmanuals.com)
  • This chapter examines these diseases and, in those of major importance, attempts to relate them to the potentially pathogenic factors present in the human diet. (clinicalgate.com)
  • PURPOSE: This study assessed the treatment outcomes of myxoid liposarcoma in the extremities and investigate the prognostic factors. (koreamed.org)
  • This report reviews the physiological roles of chemokines and their receptors in the context of hematopoietic cell regulation, with particular focus on the involvement of stromal cell derived factor (SDF)-l/pre-B cell growth stimulating factor (PBSF) and its receptor CXCR4. (go.jp)
  • Characterization of an N-terminal Na v 1.5 channel variant - a potential risk factor for arrhythmias and sudden death? (biomedcentral.com)
  • Following, inductive signals between the developing diencephalon and the oral ectoderm, early transcription factors guide the formation of rudimentary Rathke's Pouch (rRP) and then subsequent gene regulatory pathways control the determination, proliferation, and differentiation events that establish the specialized hormone-secreting cells. (medscape.com)
  • Peeker R Aldenborg F Fall M: Nephrogenic adenoma: A study with special reference to clinical presentation. (wikipedia.org)
  • Gigantism refers to abnormally high linear growth (see the image below) due to excessive action of insulinlike growth factor I (IGF-I) while the epiphyseal growth plates are open during childhood. (medscape.com)
  • Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development. (medscape.com)
  • However, due to the contribution of many factors to the development of SSIs, it may be difficult to effectively prevent these infections, and there is a need to take various preventive measures before, during and after surgery. (jurolsurgery.org)
  • The degree of wound contamination is one of the most important factors in the development of SSIs (12). (jurolsurgery.org)
  • Deterioration of the immune system as a result of hypothermia, lifestyle disorders and other factors. (prostaline-capsules.com)
  • frequently a number of factors act in concert and their action may be facilitated by individual predisposition. (cloudaccess.net)