Causal risk factor. Medical search. Frequent questions

The contribution of polygenic influences from multiple loci have been investigated by genome-wide association and candidate gene studies, which indicate that a number of genes and molecular pathways contribute to the risk of stone formation. (nature.com)
cGAUGE also uses ExSep (Exposure-based Separation), a novel test for the existence of causal pathways that does not require selecting instruments. (nature.com)
The systematic review identified ten risk factors consistently associated with CP and the authors propose the development of a clearinghouse of observational and experimental data that may help researchers pinpoint causal pathways for CP. (cdc.gov)
To have the best chance at prevention, a clear understanding of the causal pathways to CP will indeed be critical. (cdc.gov)
Network analysis of disrupted genes with high brain expression identified significant enrichment in pathways of the cholinergic synapse, guanine-exchange factor activation and the mammalian target of rapamycin. (bmj.com)
Understanding the risk factors and complex causal pathways to CP has been a slow and protracted process. (novapublishers.com)
This prevents a full understanding of causal pathways towards the shared risk of these diseases and the development of coordinated preventive and therapeutic interventions. (plos.org)
More experimental research is also needed to triangulate these findings and understand causal pathways. (who.int)

Mendelian randomisation studies use genetic variants that are independent from environmental and genetic confounders in order to strengthen causal inference. (cam.ac.uk)
Causal inference via Mendelian randomization requires making strong assumptions about horizontal pleiotropy, where genetic instruments are connected to the outcome not only through the exposure. (nature.com)
Causal inference from observational data is a fundamental objective that has been receiving increasing attention in multiple domains including biology, epidemiology, and economics. (nature.com)
Graphical models are a cornerstone of causal inference as they explicitly describe the generating process of the observed data. (nature.com)
Due to their size and depth, these datasets offer new opportunities for discovery and inference of causal relationships between traits. (nature.com)
Using variable importance measures from causal inference to rank risk factors of schistosomiasis infection in a rural setting in China. (sutterhealth.org)
Causal inference and prediction in health studies: environmental exposures and schistosomiasis, HIV-1 genotypic susceptibility scores and virologic suppression, and risk of hospital readmission for heart failure patients. (sutterhealth.org)
Risk factors for cerebral palsy: current knowledge and future causal inference. (cdc.gov)
The causal inference study to determine the association of genetically predicted biological, behavioral, ethnic factors with risk of atrial fibrillation and its associated complications. (ukbiobank.ac.uk)
By utilizing large datasets to identify genetic variants and their phenotype responsible for the occurrence of AF, an exact causal inference between genetically potential risk factors and AF would be possible. (ukbiobank.ac.uk)

The MR analyses also identified potential causal effects of ADAMTS13 and vWF on different sub-phenotypes of endometrioses. (biomedcentral.com)
In this study, we aimed to examine the association between vitamin D and COVID-19 risk and outcomes, and to explore potential causal effects. (medrxiv.org)

More epidemiological research is required before strong causal linkages can be established. (cdc.gov)
A vast body of international scientific literature has established a strong causal association between job stress and cardiovascular diseases (CVD) and other chronic health conditions. (cdc.gov)

Here, we used a genetically-informed design, Mendelian Randomization (MR), to infer the causal impact of 15 risk factors on annual total healthcare costs. (ramaonhealthcare.com)
Two-sample mendelian randomization of serum lipid level and the risk of CKD. (biomedcentral.com)
To investigate the causal relationship between coagulation factors and the risk of endometriosis, a two-sample Mendelian randomization (MR) analytic framework was used. (biomedcentral.com)
Linkage disequilibrium score regression and Mendelian Randomization (MR) analyses were applied to investigate shared genetic mechanisms (horizontal pleiotropy) and causal relationships (mediated pleiotropy) among these traits. (biorxiv.org)
This study obtained instrumental variables of 211 GM taxa from the Genome Wide Association Study (GWAS), and mendelian randomization (MR) study was carried out to assess the effect of gut microbiota on ME/CFS risk from UK Biobank GWAS (2076 ME/CFS cases and 460,857 controls). (frontiersin.org)
Aims: The aim of this study is to identify the causal association of genetically potential biological, behavioral, ethnic factors with risk of atrial fibrillation (AF) and risk of its associated complications using mendelian-randomization. (ukbiobank.ac.uk)

Mendelian randomisation uses genetic variation as a natural experiment to investigate the causal relations between potentially modifiable risk factors and health outcomes in observational data. (bmj.com)
Scientists from the International Agency for Research on Cancer (IARC), with collaborators from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study, have linked blood compounds that have previously been associated with risk of breast cancer to the potentially modifiable lifestyle factors that give rise to them. (who.int)

We conducted a systematic review of studies (N = 19) using Mendelian randomisation to examine the causal role of putative risk factors for psychopathology-related outcomes including depression, anxiety, psychological distress, schizophrenia, substance abuse/antisocial behaviour, and smoking initiation. (cam.ac.uk)

In most cases, risk factors were strongly associated with psychopathology-related outcomes in conventional analyses but Mendelian randomisation indicated that these associations were unlikely to be causal. (cam.ac.uk)
This reductionist approach relies on correlation and regression analyses and, despite the vast effort to predict sports injuries, it has been limited in its ability to successfully identify predictive factors. (bmj.com)
Logistic regression and Bayes analyses were used to evaluate the association of LH with presence and size of leiomyomata, adjusting for age, and other risk factors. (rti.org)
Main outcome measures National trends in incidence of PCCRC (within 6-36 months of colonoscopy), univariable and multivariable analyses to explore factors associated with occurrence, and funnel plots to measure variation among providers. (bmj.com)

Sixteen years after the publication of the first evidence that cannabis may be a causal risk factor for later schizophrenia ( Reference Andréasson, Allebeck and Engström And réasson et al , 1988 ), four recent prospective epidemiological studies have provided further evidence. (cambridge.org)
This systematic review of 58 observational studies identified hypothetical causal mechanisms explaining the effects of short and long intervals between pregnancies on maternal, perinatal, infant, and child health, and critically examined the scientific evidence for each causal mechanism hypothesized. (nih.gov)
Ideally, evidence of causal effects comes from well conducted randomised trials. (bmj.com)
These methods can give useful evidence about causal relations if we measure enough confounders so that, after adjustment or matching, study participants who consume different amounts of alcohol are otherwise comparable. (bmj.com)
However, the cumulative evidence for specific environmental factors is limited and inconsistent. (cdc.gov)
Most likely, this can to some extent be explained by the increased risk of osteoarthritis among former elite athletes, as demonstrated in studies on Swedish soccer players, 12, 13 However, there is no evidence to prove that repair of the ruptured ACL or isolated cartilage lesions prevents further development of osteoarthritis. (bmj.com)
Though less robust, evidence is accumulating that in some cases, dietary factors may also play a role. (chadd.org)
Using data from the Behavioral Risk Factor Surveillance System, we provide evidence that health care reform in Massachusetts led to better overall self-assessed health. (nber.org)
Evidence from previous studies have implicated an important association between gut microbiota (GM) and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), but whether there is a definite causal relationship between GM and ME/CFS has not been elucidated. (frontiersin.org)
Until relatively recently, there was simply no rigorous statistical framework for measuring the strength of evidence for causal relationships in medical research, much less for differentiating types of causal relationships. (cdc.gov)
A better understanding of disaster risk factors and hazards would support evidence-informed decisions relevant to Health EDRM. (who.int)
No evidence of the causal relationship was observed for cancers on SS. (biomedcentral.com)
SS had significant causal relationships with lymphomas, prostate cancer, and endometrial cancer, and suggestive evidence of association was found in liver and bile duct cancer and cancer of urinary tract, indicating that SS may play a vital role in the incidence of these malignancies. (biomedcentral.com)
Evidence for the pathophysiological overlap of these conditions is mounting, although a causal relationship is yet to be established. (springer.com)
Thus, further evidence independent of reverse causation or confounding is needed to identify meaningful causality between AF and risk factors. (ukbiobank.ac.uk)
In conclusion, our study found suggestive evidence of association between vitamin D and the risk or severity of COVID-19 but further studies are needed. (medrxiv.org)
Furthermore, there is evidence that COVID-19 disproportionately affects black and minority ethnic individuals, with one potential explanation - in addition to other risk factors - being the higher prevalence of vitamin D deficiency ( 6 ). (medrxiv.org)
Causal explanations as a risk factor for depression: Theory and evidence. (bvsalud.org)

14 Jørgensen AB, Frikke-Schmidt R, West AS, Grande P, Nordestgaard BG, Tybjærg-Hansen A. Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. (thieme-connect.com)
Higher scores, corresponding to greater consumption of the six food categories, tracked with significantly reduced risks for death, myocardial infarction (MI), and stroke . (medscape.com)

On 96 complex traits from 337,198 subjects from the UK Biobank, our results cover expected causal links and many new ones that were previously suggested by correlation-based observational studies. (nature.com)
Our two-sample MR analysis of 11 coagulation factors in the UK Biobank suggested a reliable causal effect of genetically predicted plasma ADAMTS13 level on decreased endometriosis risk. (biomedcentral.com)
We used logistic regression to identify associations between different vitamin D variables (25-hydroxyvitamin D concentration (25-OHD), ambient UVB and genetically-predicted 25-OHD concentrations) and COVID-19 (risk of infection, hospitalisation and death) in 495,780 participants from UK Biobank. (medrxiv.org)

After correcting the heterogeneity and horizontal pleiotropy, the results indicated that patients with SS were significantly associated with an increased risk of lymphomas (odds ratio [OR] = 1.0010, 95% confidence interval [CI]: 1.0005-1.0015, P = 0.0002) and reduced risks of prostate cancer (OR = 0.9972, 95% CI: 0.9960-0.9985, P = 2.45 × 10 −5 ) and endometrial cancer (OR = 0.9414, 95% CI: 0.9158-0.9676, P = 1.65 × 10 −5 ). (biomedcentral.com)

Overview: Linear panel event studies are increasingly used to estimate and plot causal effects of changes in policies. (nber.org)
We present semi-parametric methods for identifying risk factors through a comparison of three analysis approaches: a prediction-focused machine learning algorithm, a simple main-effects multivariable regression, and a semi-parametric variable importance (VI) estimate inspired by a causal population intervention parameter. (sutterhealth.org)
CONCLUSIONS: The July VI estimate suggests possible within-season variability in schistosomiasis infection risk, an association not detected by the regression analysis. (sutterhealth.org)
The inverse variance weighted (IVW) method was used to estimate the causal effects. (biomedcentral.com)

A lack of causal effects was observed for certain clinically relevant biomarkers, such. (ramaonhealthcare.com)
While some data exist on biomarkers that are related to FEV1, we sought to do a systematic analysis of causal relations of biomarkers with FEV1. (researchgate.net)

Understanding the causal impact that clinical risk factors have on healthcare-related costs is critical to evaluate healthcare interventions. (ramaonhealthcare.com)
Patients and clinicians can discuss the potential risks and benefits of using PFAS blood testing results to guide clinical management. (cdc.gov)
Background Despite established clinical associations among major depression (MD), alcohol dependence (AD), and alcohol consumption (AC), the nature of the causal relationship between them is not completely understood. (biorxiv.org)
The clinical significance and causal relationship are uncertain. (gabio.org)
Basic information about the temporal and causal patterns of viral shedding and their relationships to clinical outcomes is critical to further understand the virus and to shape prevention and control measures needed to limit transmission. (cdc.gov)

6 9 Suppose, for example, we wanted to investigate the effects of alcohol consumption on blood pressure with a view to understanding the overall relationship of alcohol with risk of coronary heart disease. (bmj.com)
This association may be a poor indicator of the causal effects of alcohol if there are other factors-"confounders"-that influence both alcohol intake and blood pressure. (bmj.com)
This chapter outlines areas of disaster risk and discusses how research can be used to determine the causes of the problem, and how these causes and the size of their effects can be measured reliably. (who.int)
Additional MR analysis indicated that causal effects between SS and cancers were not mediated by the well-accepted risk factors of cancers. (biomedcentral.com)
This includes providing health screenings and health risk appraisals, and teaching skills such as relaxation and meditation, conflict resolution, and healthy lifestyle behavior-all classic examples of secondary prevention (early detection of symptoms and minimizing adverse health effects). (cdc.gov)

Causal criteria that deal with the exposure-disease relationship are often used as general guidelines for ascertaining causes. (cambridge.org)
Risk factors that either augment the likelihood of asthma developing upon exposure to them, or may even increase susceptibility to asthma. (cdc.gov)
Alternatively, a risk factor can be due to environmental exposure. (cdc.gov)
Thus, exposure to environmental risk factors affects some children more than others. (chadd.org)
How hazards, exposure, and vulnerability/capacity create disaster risk. (who.int)
Changing organizational behaviour to reduce exposure risk: vaccination to prevent congenital rubella syndrome. (who.int)
Risk assessments using the Strain Index and the TLV for HAL, Part I: Task and multi-task job exposure classifications. (uwm.edu)
In 2007, the World Health Assembly adopted a resolution on oral health.4 The document listed priority actions for tackling the social determinants of oral health and reducing exposure to common risk factors of noncommunicable diseases (NCDs). (who.int)

The following hypothetical causal mechanisms for explaining the association between short intervals and adverse outcomes were identified: maternal nutritional depletion, folate depletion, cervical insufficiency, vertical transmission of infections, suboptimal lactation related to breastfeeding-pregnancy overlap, sibling competition, transmission of infectious diseases among siblings, incomplete healing of uterine scar from previous cesarean delivery, and abnormal remodeling of endometrial blood vessels. (nih.gov)
Women's physiological regression is the only hypothetical causal mechanism that has been proposed to explain the association between long intervals and adverse outcomes. (nih.gov)
However, whether the concurrent existence of sarcopenia, osteoporosis and obesity leads to an increased risk of adverse musculoskeletal outcomes and mortality above and beyond the risks associated with the sum of the component parts remains to be proven and is a question of research interest. (springer.com)

At the population level, elimination of cannabis use would reduce the incidence of schizophrenia by approximately 8%, assuming a causal relationship. (cambridge.org)
Therefore, the purpose of this study is to use publicly available GWAS summary statistics to examine the causal relationship between coagulation factors and the risk of endometriosis. (biomedcentral.com)
This study reveals a causal relationship between genus paraprevotella , genus Ruminococcaceae_UCG_014 and ME/CFS, and our findings provide novel insights for further elucidating the developmental mechanisms mediated by the gut microbiota of ME/CFS. (frontiersin.org)
Or is a given risk factor part of a causal chain, influencing other causal factors but having no direct relationship to CP? (cdc.gov)
Has the claim that there's a causal relationship between poor air quality and death been debunked? (stackexchange.com)
Is it true that this study 'Air quality environmental epidemiology studies are unreliable' by Stan Young debunks the EPA's claim that there a causal relationship between poor air quality and death? (stackexchange.com)
It does not seek to respond to the overarching question of whether or not there is a causal relationship between poor air quality and death. (stackexchange.com)
In existing observational studies investigating the causal relationship between potential risk factors and the development of AF, reverse causality and additional confounding were inevitable. (ukbiobank.ac.uk)
The decline in physical activity level is behaviour change theories to identify questionnaire for assessing physical greatest during the secondary-school the main factors influencing behaviour activity in Iranian female adolescent years (12-18 years), and previously as well as any possible relationship students (SCT-PAIAGS). (who.int)

A previous review paper, published more than a decade ago, reached no firm conclusion regarding causality and stressed the importance of prospective longitudinal population-based cohort studies to elucidate a possible causal association ( Reference Thornicroft Thornicroft, 1990 ). (cambridge.org)
Support for each criterion strengthens the case for a causal association but, as Rothman & Greenland ( Reference Rothman and Greenland 1998 ) point out, only one criterion, temporality, is a sine qua non for causality. (cambridge.org)
These associations may indicate possible mechanisms underlying associations between lifestyle factors and risk of breast cancer, although the direction and causality of these links are yet to be determined. (who.int)

The Agency for Toxic Substances and Disease Registry (ATSDR), a public health agency of the U.S. Department of Health and Human Services, today released its review of motor neuron disease/amyotrophic lateral sclerosis (MND/ALS) risk factors and mortality in Bexar County, Texas. (cdc.gov)
The report is titled "Motor Neuron Disease/Amyotrophic Lateral Sclerosis: Preliminary Review of Environmental Risk Factors and Mortality in Bexar County, Texas. (cdc.gov)
Regular physical activity reduces the risk of premature mortality in general, and of coronary heart disease, hypertension, colon cancer, obesity, and diabetes mellitus in particular. (bmj.com)
Hypertriglyceridaemia as a risk factor of coronary heart disease mortality in subjects with impaired glucose tolerance or diabetes. (thieme-connect.com)
Reductions in mortality and CV-disease risk that were linked to the higher scores were especially pronounced in lower-income countries in the study published online July 6 in the European Heart Journal with lead author Andrew Mente, PhD, Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. (medscape.com)
But it is consistent with earlier findings from PURE of reduced mortality risk with increased consumption of dietary fat, including saturated fat. (medscape.com)
The COVID-19 pandemic death toll now surpasses two million individuals and there is a need for early identification of individuals at increased risk of mortality. (medrxiv.org)
Host genetic variation partially drives the immune and biochemical responses to COVID-19 that lead to risk of mortality. (medrxiv.org)
Public health impact: In the context of the increasing epidemiological burden of AF, considering that AF is highly associated with cardiovascular morbidity and mortality, identification and control of genetically predicted potential risk factors for the development of AF could be the key to reduce the future burden of AF and its cardiovascular complications. (ukbiobank.ac.uk)

Mendelian randomisation is an analytical method that uses genetic variants as instrumental variables for modifiable risk factors that affect population health. (bmj.com)
How can workplace health promotion professionals address job stress as a modifiable risk factor for heart disease and other chronic diseases? (cdc.gov)

Notably, we identify multiple risk factors for cardiovascular disease, including red blood cell distribution width. (nature.com)
Hypertriglyceridemia is associated with an increased risk of both cardiovascular disease ( 1,2 ) and acute pancreatitis ( 3,4 ). (lww.com)
Association Between Cardiovascular Disease Risk Factors and Rotator Cuff Tendinopathy. (uwm.edu)
Shift workers, who frequently undergo circadian misalignment, are at greater risk for hypertension, inflammation, and cardiovascular disease, even after accounting for traditional risk factors. (concordia.ca)

Various robustness checks and placebo tests support a causal interpretation of the results. (nber.org)
An a priori causal model enabled survey development, data analysis, and interpretation. (healthpartners.com)

Life-course models will integrate the role of modifying factors as sex, socioeconomics, and lifestyle with the goal to better identify groups at risk as well as inform promising strategies to reverse the possible mechanisms and/or reduce the impact of ELS on multi-morbidity development in high-risk individuals. (plos.org)

Changes in triglyceride levels and risk for coronary heart disease in young men. (thieme-connect.com)
Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. (thieme-connect.com)

Remnant cholesterol as a causal risk factor for ischemic heart disease. (thieme-connect.com)

Effective interventions need to target risk factors that are causally related to psychopathology. (cam.ac.uk)
Controversy exists on whether OSA and nocturnal reflux are causally linked or merely associated because of shared risk factors. (nih.gov)

present a useful systematic review of studies of risk factors for cerebral palsy (CP) in term births. (cdc.gov)

Factors contributing to variability of quantitative viral PCR results in proficiency testing samples: a multivariate analysis. (sutterhealth.org)

Algorithms for causal discovery identify patterns of conditional independencies (CI) with theoretical justification for refuting candidate models that are unlikely to have generated the observed data. (nature.com)
BACKGROUND: The COVID-19 pandemic and its associated public health mitigation strategies have dramatically changed patterns of daily life activities worldwide, resulting in unintentional consequences on behavioral risk factors, including smoking, alcohol consumption, poor nutrition, and physical inactivity. (bvsalud.org)

Using matched-pair methods, the researchers compared risk factors. (wikipedia.org)
However, the researchers could not conclude a causal effect of fish oil supplements on cognition and brain atrophy. (nutraingredients-usa.com)
By analysing publicly available patient data, researchers have discovered a strong correlation between vitamin D deficiency and COVID-19 risk ( 5 ). (medrxiv.org)

These findings suggest that these coagulation factors are involved in the development of endometriosis and may represent potential therapeutic targets for the management of this complex disease. (biomedcentral.com)
Findings from this large, long-term, randomised controlled trial suggest that a multidomain intervention could improve or maintain cognitive functioning in at-risk elderly people from the general population. (researchgate.net)

The methodology for studies designed to investigate potential risk factors for sports injury is reviewed, using the case of hamstring strains as an example. (bmj.com)

Increased understanding of the genetic factors contributing to kidney stone disease helps to improve our understanding of the pathogenesis of this condition. (nature.com)
Advances in our understanding of the polygenic factors contributing to risk of kidney stone disease might enable a precision medicine approach. (nature.com)
Understanding individual vulnerability as health risk: cold weather impacts and the social determinants of health. (who.int)
Understanding the basics of some of these human factors, as well as appropriate mitigation techniques, can keep flying more efficient, and above all, safe. (faa.gov)

Determining where the causal arrows lie is the key challenge for the current generation of scientific studies. (chadd.org)

CONCLUSIONS: This analysis provided insight into behavioral cancer risk factors as expressed on Twitter during the first year of the COVID-19 pandemic. (bvsalud.org)

This novel view of preventive intervention relies on the identification of regularities or risk profile, moving from risk factors to risk pattern recognition. (bmj.com)
The identification of these factors will enable more effective intervention strategies to be developed and implemented by employers and employees. (cdc.gov)
In the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER), a proof-of-concept randomised controlled trial, we aimed to assess a multidomain approach to prevent cognitive decline in at-risk elderly people from the general population. (researchgate.net)
We randomly assigned participants in a 1:1 ratio to a 2 year multidomain intervention (diet, exercise, cognitive training, vascular risk monitoring), or a control group (general health advice). (researchgate.net)

7, 8 ACL injury causes lengthy absence from work and sports, and dramatically increases the risk of long term sequelae-like abnormal joint dynamics and early onset of degenerative joint disease. (bmj.com)
High Triglyceride Variability Increases the Risk of First At. (lww.com)
Parallel runways with staggered thresholds are a leading causal factor that increases the risk of pilots landing on the wrong surface. (faa.gov)

To address wrong surface events where an aircraft lines up to, lands on, or departs from the incorrect runway, taxiway, or airport, the FAA released Arrival Alert Notices in the May 19, 2022 charting cycle for several airports with a history of misalignment risk. (faa.gov)
Arrival Alert Notices provide a graphic visually depicting the approach to a particular airport with a history of misalignment risk. (faa.gov)
There is also language describing the misalignment risk area. (faa.gov)
yet, intriguing questions have been raised about the plausible causal relations linking sleep, circadian misalignment, and cardiometabolic disorders. (concordia.ca)

Here, we present causal Graphical Analysis Using Genetics (cGAUGE), a pipeline that overcomes these limitations using instrument filters with provable properties. (nature.com)
Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration. (thieme-connect.com)
Sarcopenia and osteoporosis have similar risk factors that include genetics, endocrine function, and mechanical factors. (springer.com)

This handbook discusses the risk factors of cerebral palsy, as well as the therapeutic management options, and long-term prognosis of the condition. (novapublishers.com)

Nevertheless, the causal relationships remain unclear. (biomedcentral.com)
Scientific rationale: To date, many environmental and genetic risk factors have been revealed in the development of AF, but associations between these risk factors and AF are remarkably complex and unclear. (ukbiobank.ac.uk)
It is unclear whether this association is causal or explained by reverse causation or confounding. (lu.se)

The most commonly examined risk factors in the reviewed Mendelian randomisation studies were smoking, alcohol use and body mass index. (cam.ac.uk)

A large literature indicates an important effect of APOE4 on lifestyle interventions aimed at mitigating the increased risk of AD. (researchgate.net)
Associated increased injury risks require further investigation and targeting of relevant interventions. (healthpartners.com)

Sample size mainly depends on the expected effect of the risk factor on injury risk, and to detect moderate to strong associations 20-50 injury cases are needed, whereas small to moderate associations would need about 200 injured subjects. (bmj.com)
A negative causal effect of ADAMTS13 and a positive causal effect of vWF on endometriosis were observed in the FinnGen. (biomedcentral.com)
In the meta-analysis, the causal associations remained significant with a strong effect size. (biomedcentral.com)
No causal effect of SS on other cancer types was detected. (biomedcentral.com)
We subsequently performed a Mendelian Randomisation (MR) study to test if there was any causal effect. (medrxiv.org)

In this regard, our challenge as a field is to isolate "what works for whom" to identify the precise factors that influence each individual person's expression of ADHD. (chadd.org)
Objective To identify rare, causal CNV in patients with RE. (bmj.com)
2. Identify 3 limitations inherent in using risk assessment tools to verify the link between personality disorder and dangerousness (namely, categorical DSM classifications, the influence of social norms, and the redundancy of definitions that include aggression). (psychiatrictimes.com)
Sentiments and emotions for each of the risk factors were evaluated over time and analyzed to identify keywords that emerged. (bvsalud.org)

The ATSDR report discusses several environmental risk factors that have been investigated for an association with the risk of acquiring ALS. (cdc.gov)

Our MR analysis based on GWAS data from large-scale population studies demonstrated the causal associations between ADAMTS13/vWF and the risk of endometriosis. (biomedcentral.com)

recognise correlations and causal relationships. (aqa.org.uk)

RESULTS: The multivariable regression found only tool washing to be associated with the outcome, with a relative risk of 1.03 and a 95% confidence interval (CI) of 1.01-1.05. (sutterhealth.org)

Assess risk factors for L. longbeachae pneumonia. (cdc.gov)
How to conduct a study to assess disaster risk factors. (who.int)
Moreover, additional analysis was used to assess the associations between SS and well-accepted risk factors of cancers. (biomedcentral.com)

OBJECTIVE: We explored the feasibility of conducting a sentiment and emotion analysis using Twitter data to evaluate behavioral cancer risk factors (physical inactivity, poor nutrition, alcohol consumption, and smoking) over time during the first year of the COVID-19 pandemic. (bvsalud.org)
OBJECTIVE: To explore if older adults with osteosarcopenia are at a greater risk of falls, fractures, frailty, and worsening life satisfaction and activities of daily living (ADL) compared to those with normal bone mineral density (BMD) and without sarcopenia. (bvsalud.org)

Though there are many limitations to this study that temper the potential for causal interpretations, if a high-risk time period could be detected in something close to real time, new prevention options would be opened. (sutterhealth.org)
In this multi-institutional cohort study, high triglyceride variability was associated with an increased risk of first attack of acute pancreatitis, independent of baseline and mean triglyceride levels. (lww.com)
This study addressed a knowledge gap regarding large machinery-related injury magnitude, consequences, and risk factors. (healthpartners.com)
This study aims to address the prevalence for and risk factors of comorbid depression among Jordanian and Syrian women with known chronic disease. (who.int)
A previous study examined concentrations of more than 120 blood metabolites and found that the concentrations of eight of these metabolites were associated with an increased risk of breast cancer development. (who.int)

Studies published to date on the risk factors for hamstring strains have methodological limitations, and are too small to detect small to moderate associations. (bmj.com)
This article examines the empirical literature on the link between personality disorders and dangerousness, the limitations inherent in using risk assessment tools to verify the link, and the ethical issues surrounding the assessment. (psychiatrictimes.com)

An accumulation of both environmental disadvantages and genetic risk factors will move individuals along that spectrum-sometimes in a subtle way, other times more markedly. (chadd.org)

METHODS: Tweets during 2020 relating to the COVID-19 pandemic and the 4 cancer risk factors were extracted from the George Washington University Libraries Dataverse. (bvsalud.org)

In order to evaluate factor structure, cross-sectional research was conducted on 400 high-school girls in Tehran. (who.int)

Standard principal component analysis-based factor analysis suffers from a number of well-known problems due to the random nature of pairwise correlations of asset returns. (risk.net)
This analysis identified several modifiable factors correlated to blood concentrations of metabolites associated with risk of breast cancer, such as alcohol consumption and adiposity. (who.int)
An analysis of the most frequent words tweeted revealed further insights into common themes expressed in relation to some of the risk factors and possible sources of bias. (bvsalud.org)
Confirmatory factor analysis approved a six-factor structure comprising self-efficacy, self-regulation, family support, friend support, outcome expectancy and self-efficacy to overcoming impediments. (who.int)

In 1993, Arthur Kellermann and colleagues obtained data from police and medical examination records on risk factors in the home of occurring homicides. (wikipedia.org)
We have to be honest with ourselves - for the most part we have been pretty conservative as an industry in how we have utilized data in assessing pipeline condition, risk levels and operational performance. (dnv.com)
As the asset ages, operators need to mine, review and spot trends in the data so they can preempt problems that will elevate risk levels. (dnv.com)
This update reviews new data on causal links between sleep and gastroesophageal reflux disease. (nih.gov)
Previous data indicates that carriers of the APOE4 allelic variant (about 25% of whites) are at a several-fold increased risk of Alzheimer's disease. (nutraingredients-usa.com)
The infodemic of social media data may provide novel opportunities for evaluating changes related to behavioral risk factors during the pandemic. (bvsalud.org)
It was feasible to extract tweets relating to all 4 risk factors, and most tweets had a positive sentiment with varied emotions across the different data sets. (bvsalud.org)
Factor loadings, t -values and fit indices showed that the SCT model was fitted to the data. (who.int)

These previously investigated environmental risk factors include organic chemicals, heavy metals, and agricultural chemicals. (cdc.gov)
This description is followed by a review of the available literature on suspected environmental risk factors associated with the disease. (cdc.gov)

Objectives To quantify post-colonoscopy colorectal cancer (PCCRC) rates in England by using recent World Endoscopy Organisation guidelines, compare incidence among colonoscopy providers, and explore associated factors that could benefit from quality improvement initiatives. (bmj.com)

They share risk factors with the leading NCDs, including tobacco use, harmful alcohol consumption and unhealthy diets high in sugar, all of which are increasing in the Region. (who.int)

Diseases3

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Psychiatry and Psychology1

Phenomena and Processes4

Information Science3

Health Care17

Geographicals1

Pathways8

Inference10

Potential causal effects2

Strong causal2

Mendelian Randomization6

Potentially modifiable2

Putative1

Analyses4

Evidence18

Myocardial infarction2

Biobank3

Horizontal pleiotropy1

Estimate4

Biomarkers2

Clinical5

Effects5

Exposure8

Outcomes3

Relationship9

Causality3

Mortality9

Modifiable risk2

Cardiovascular disease4

Interpretation2

Mechanisms1

Coronary heart d2

Ischemic1

Causally2

Systematic review1

Viral1

Patterns2

Researchers3

Findings2

Investigate1

Understanding4

Determining1

Conclusions1

Intervention4

Increases3

Misalignment4

Genetics3

Cerebral palsy1

Unclear3

Reviewed Mendelian randomisation1

Interventions2

Effect5

Identify4

Association1

GWAS1

Relationships1

Regression1

Assess3

Objective2

Study5

Limitations2

Genetic risk factors1

Methods1

Evaluate1

Analysis4

Data8

Environmental Risk Factors2

Incidence1

Alcohol1