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  • aromatic
  • Urushiols are naturally existing organic compounds that have the catechol skeleton structure and diphenol functionality but with alkyl groups substituted onto the aromatic ring. (wikipedia.org)
  • strain
  • In the following section we will investigate in silico predictions of metabolic flux distribution in our catechol degrading E. coli strain through Flux Balance Analysis (FBA). (igem.org)
  • It is hypothesized that the combination of glucose and catechol that is taken up by the engineered strain may have a great affect on the flux distribution throughout the remaining metabolic network. (igem.org)
  • strain Q1, a strain naturally found in soil and paper mill sludge, contains the ability to degrade quinoline, various pyridine derivatives, catechol, benzoate, and protocatechuic acid. (wikipedia.org)
  • moiety
  • Arthropod cuticle consists of chitin linked by a catechol moiety to protein. (wikipedia.org)
  • The A ring is similar to a resorcinol moiety while the B ring is similar to a catechol moiety. (wikipedia.org)
  • The ability to quench singlet oxygen seems to be in relation with the chemical structure of catechin, with the presence of the catechol moiety on ring B and the presence of a hydroxyl group activating the double bond on ring C. Electrochemical experiments show that (+)-catechin oxidation mechanism proceeds in sequential steps, related with the catechol and resorcinol groups and the oxidation is pH-dependent. (wikipedia.org)
  • extradiol
  • Extradiol members utilize ferrous iron as the active redox state, and this center is commonly coordinated octahedrally through a 2-His-1-Glu motif with labile water ligands occupying empty positions. (wikipedia.org)
  • chloride
  • Cyclic esters are formed upon treatment with phosphorus trichloride and phosphorus oxychloride, carbonyl chloride, and sulphuryl chloride: C6H4(OH)2 + XCl2 → C6H4(O2X) + 2 HCl where X = CO, SO2, PCl, P(O)Cl Catechols produce quinones with the addition of ceric ammonium nitrate (CAN). (wikipedia.org)
  • NADH
  • The enzyme 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase uses 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate and NAD+ to produce 3-methylcatechol, NADH and CO2. (wikipedia.org)
  • cleave
  • 1,2-CTD uses Fe3+ as a cofactor to cleave the carbon-carbon bond between the phenolic hydroxyl groups of catechol, thus yielding muconic acid as its product. (wikipedia.org)
  • In contrast, 2,3-CTD utilizes Fe2+ as a cofactor to cleave the carbon-carbon bond adjacent to the phenolic hydroxyl groups of catechol, thus yielding 2-hydroxymuconaldehye as its product. (wikipedia.org)
  • Biochemistry
  • This list contains a list of EC numbers for the first group, EC 1, oxidoreductases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. (wikipedia.org)
  • hydrocarbons
  • 1,2-CTD degrades phenolic hydrocarbons key to the synthesis lipid membranes. (wikipedia.org)
  • Therefore, 1,2-CTD may bind to the cell lipid membrane via its terminal phospholipids and thus have greater access to the phenolic hydrocarbons vital in lipid membrane structure. (wikipedia.org)
  • catechin
  • Catechol was first isolated in 1839 by Edgar Hugo Emil Reinsch (1809 - 1884) by distilling it from the solid tannic preparation catechin, which is the residuum of catechu, the boiled or concentrated juice of Mimosa catechu (Acacia catechu L.f). (wikipedia.org)
  • specifically
  • Specifically, we will investigate network variability at the four points indicated on Figure 1, each of which represent significantly different combinations of glucose and catechol uptake. (igem.org)
  • More specifically, one of Que's focuses is on homoprotocatechuate (HPCA) 2,3-dioxygenase, which mediates the electron transfer between catechol substrates and O2 to form a [M(II)(semiquinone)superoxo] intermediate. (wikipedia.org)
  • Alcaligenes
  • Dioxygenation and spontaneous deamination of 2-aminobenzene sulphonic acid in Alcaligenes sp. (wikipedia.org)
  • in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. (wikipedia.org)
  • iron
  • The active site of catechol dioxygenases most frequently contains iron, but manganese-containing forms are also known. (wikipedia.org)
  • Iron-containing dioxygenases can be subdivided into three classes on the basis of how iron is incorporated into the active site: those employing a mononuclear iron center, those containing a Rieske [2Fe-2S] cluster, and those utilizing a heme prosthetic group. (wikipedia.org)
  • Despite this common oxygenation event, the mononuclear iron dioxygenases are diverse in how dioxygen activation is used to promote certain chemical reactions. (wikipedia.org)
  • Most mononculear iron dioxygenases are members of the cupin superfamily in which the overall domain structure is described as a six-stranded β-barrel fold (or jelly roll motif). (wikipedia.org)
  • Two important groups of mononuclear, non-heme iron dioxygenases are catechol dioxygenases and 2-oxoglutarate (2OG)-dependent dioxygenases. (wikipedia.org)
  • In the 2OG-dependent dioxygenases, ferrous iron (Fe(II)) is also coordinated by a (His)2(Glu/Asp)1 "facial triad" motif. (wikipedia.org)
  • protein
  • The enzyme was purified about 18-fold with a specific activity of 7.42 U mg of protein−1. (semanticscholar.org)
  • In recent years, 2-D electrophoresis has been widely accepted as a standard procedure to separate complex protein mixtures in proteome studies (Proteomics). (wikipedia.org)
  • thus
  • Thus, the rates of catechol and glucose uptake are good candidates to be experimentally measured, and then set as constraints in model simulations. (igem.org)
  • acid
  • Its methyl ether derivative, guaiacol, converts to catechol via hydrolysis of the CH3-O bond as promoted by hydriodic acid. (wikipedia.org)
  • Catechol is the conjugate acid of a chelating agent used widely in coordination chemistry. (wikipedia.org)
  • structure
  • Catecholamines are biochemically significant hormones/neurotransmitters that are phenethylamines in which the phenyl group has a catechol skeleton structure. (wikipedia.org)
  • shown
  • Though prediction of metabolic flux and microbial growth rate has been shown to be generally accurate through this method, experimental usage of catechol may be significantly higher or lower than the purely stoichiometric prediction. (igem.org)
  • Catechol has since been shown to occur in free-form naturally in kino and in beechwood tar. (wikipedia.org)