• This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. (antibodies-online.com)
  • This enzyme is useful as an indicator enzyme when coupled to antibodies used in enzyme-based immunoassay systems. (scrippslabs.com)
  • This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. (biossusa.com)
  • An essential step in demonstrating the success of a designer enzyme, therefore, is the determination of a high-resolution crystal structure for the protein, to verify that the designed catalytic features are present. (nature.com)
  • GTP-bound GαT subunits then interact with their effector protein, the cyclic GMP (cGMP) phosphodiesterase-6 (PDE6), a tetrameric enzyme with two catalytic subunits (PDEα, PDEβ) and two subunits (PDEγ) that bind GαT. (cornell.edu)
  • One of those ions is crucial for the operation of the enzyme: it is located at the catalytic site and holds the hydroxyl group of the alcohol in place. (biobool.com)
  • Only those wells that contain ADH, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. (biobool.com)
  • They have also shown that encapsulation increases the stability of the catalysts in the presence of biological catalysts and therefore provides a strategy for carrying out tandem gold-enzyme catalyzed processes. (berkeley.edu)
  • Phosphatidylinositol 3-kinase (PI 3-kinase) is the enzyme that catalyzes the phosphorylation of the D-3 position of phosphatidylinositol (PI) and its derivatives. (edrc2013.org)
  • Its activation into the serine-protease-like enzyme, activated protein C (aPC), is catalyzed by thrombin when it is bound to the endothelial proteoglycan thrombomodulin. (medscape.com)
  • Lerner's research into catalytic antibodies provided a method of catalyzing chemical reactions thought impossible using classical techniques. (wikipedia.org)
  • He and his colleagues were redesigning antibodies so that they could drive chemical reactions, but List started wondering if a single amino acid could also work as a catalyst. (nordiclifescience.org)
  • Antibodies that can catalyze a wide variety of chemical reactions. (edu.au)
  • To date, all L-proline assisted aldol-type reactions are considered to proceed via the same biomimetic catalytic cycle involving the formation of an enamine intermediate. (aiche.org)
  • Therefore, to understanding the origin of the unusual kinetic behavior in certain L-proline-catalyzed reactions, we used density functional theory (DFT) to map the reaction coordinates of an aldol addition and an α-aminoxylation reaction. (aiche.org)
  • Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (ximbio.com)
  • Minimalist enzymes designed to catalyze model reactions provide useful starting points for creating catalysts for practically important chemical transformations. (bvsalud.org)
  • They describe a method for designing enzymes that catalyse unnatural reactions, and demonstrate its use for two different chemical transformations. (nature.com)
  • Catalytically inactive proteins have been converted into modestly catalytic ones for two different reactions, but the observed enhancements of rate 6 , 7 were only about a millionth of those produced by naturally occurring enzymes. (nature.com)
  • The identification of setting pleasant catalytic packages along with huge substrate scope made these cross-couplings key reactions to entry useful molecules ranging from provides, agrochemicals to vigorous pharmaceutical parts. (naclaitesque.com)
  • In general, chemical reactions occur faster in the presence of a catalyst because the catalyst provides an alternative reaction mechanism (reaction pathway) having a lower activation energy than the non-catalyzed mechanism. (wikipedia.org)
  • In convergent evolution, nonhomologous proteins evolve in separate biological contexts to catalyze the same or similar reactions. (hindawi.com)
  • There exist two types of convergent evolution: (1) mechanistic analogs that uses the same mechanisms to perform related reactions and (2) transformational analogs catalyzing exactly the same reaction. (hindawi.com)
  • Proteins perform a vast array of functions within organisms, including catalyzing metabolic reactions, DNA replication, responding to stimuli providing structure to cells and organisms, and molecules from one location to another. (transectscience.org)
  • Many proteins are enzymes that catalyze biochemical reactions and are vital to metabolism. (transectscience.org)
  • Research efforts in the Toste Group have profoundly impacted the development of gold(I)-catalyzed reactions. (berkeley.edu)
  • They enumerated the concept of addition/back-donation that is now heavily employed as a method to generate gold-carbenoid reactivity from alkynes and they described the dual activation paradigm that forms the basis many gold-catalyzed reactions currently being explored by many groups. (berkeley.edu)
  • More recently, they have demonstrated that catalysis in the supramolecular host confers unique selectivity on traditional homogeneous catalyzed reactions, such as hydrogenation. (berkeley.edu)
  • Catalysis Research is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. This periodical is devoted to publishing high-quality papers that describe the most significant and cutting-edge research in all areas of catalysts and catalyzed reactions. (lidsen.com)
  • Each subunit contains two molecules of zinc, necessary for stability and catalytic activity. (scrippslabs.com)
  • STT3A is a catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. (themarketreports.com)
  • This pathway starts with the absorption of a photon by the GPCR rhodopsin, resulting in its activation of the heterotrimeric G protein transducin by catalyzing GDP-GTP exchange on the transducin-alpha subunit (GαT). (cornell.edu)
  • PI 3-kinase, which is mainly activated by tyrosine kinases, consists of two subunits: a catalytic 110-kDa subunit (p110) and a regulatory 85-kDa subunit (p85) (4). (edrc2013.org)
  • Activation of AMPK can be assessed using a phosphospecific antibody (anti-pAMPK) that recognizes either catalytic subunit isoform (α1 or α2), but only when phosphorylated at Thr-172. (biomedcentral.com)
  • Explore our solutions for multiple applications - vaccines, monoclonal antibodies, recombinant proteins, cell or gene therapy. (vwr.com)
  • The N-terminal domain of APOBEC-1 like proteins is the catalytic domain, while the C-terminal domain is a pseudocatalyitc domain. (embl.de)
  • It should be pointed out that although the two proteins (PPDK and PEPS) share some homology, especially around a central catalytic site, they can be identified using the signature sequences identified by Tjaden and colleagues [10]. (scirp.org)
  • With these precedents, you might think that designing catalytic proteins should be straightforward, but success has been limited. (nature.com)
  • In living organisms, this reaction is catalyzed by enzymes (proteins that serve as catalysts) such as catalase . (wikipedia.org)
  • Several methods have been proposed to design novel stable proteins, such as multi-objective optimization, in which protein stability and catalytic activity are simultaneously optimized. (hindawi.com)
  • Purification of individual SARS-CoV-2 proteins from human cells have identified a potential interaction between a catalytic-inactive version of Nsp5 with human tRNA methyltransferase 1 (TRMT1) ( Gordon et al , 2020b ). (elifesciences.org)
  • COX11 Polyclonal Antibody detects endogenous levels of COX11 protein. (abbkine.com)
  • COX42 Antibody detects endogenous levels of total COX42. (affbiotech.cn)
  • One of the methods that have been proposed is a multiobjective optimization, in which protein stability and catalytic activity are simultaneously optimized [ 4 , 5 ]. (hindawi.com)
  • Thus fast analyses can be performed even with small sample volumes and significantly lower amounts of antibodies and reagents are required [ 1 ]. (hindawi.com)
  • While conventional methods can be plagued by harsh reaction conditions, corrosive reagents and costly protecting groups, enzymes and catalytic antibodies have high substrate specificity. (aiche.org)
  • Cobalt-Catalyzed Cross-Couplings between Alkyl Halides and Grignard Reagents ConspectusMetal-catalyzed cross-couplings have emerged as necessary devices for the event of C-C bonds. (naclaitesque.com)
  • Here we exploit the catalytic activity of silver nanoparticles (Ag NPs) in a surface based silver-linked immunosorbent assay (SLISA) to detect human C-reactive protein (CRP), an inflammatory marker. (strath.ac.uk)
  • Pauling believed that protein shapes-independently of amino acid sequences-determined antibody specificity and biological specificity in general. (ucpress.edu)
  • Protein tyrosine kinases are enzymes that catalyze the transfer of phosphate from ATP to tyrosine residues in polypeptides. (aacrjournals.org)
  • This examine focuses on sirtuins, which catalyze the response of NAD+-dependent protein deacetylase, for riboflavin manufacturing in A. gossypii. (aabioetica.org)
  • Catalytic domain of Epidermal Growth Factor Receptor-like Protein Tyrosine Kinases. (umbc.edu)
  • The PTKc family is part of a larger superfamily that includes the catalytic domains of other kinases such as protein serine/threonine kinases, RIO kinases, and phosphoinositide 3-kinase (PI3K). (umbc.edu)
  • PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates. (umbc.edu)
  • Human cells infected with SARS-CoV-2 exhibit a decrease in TRMT1 protein levels and TRMT1-catalyzed tRNA modifications, consistent with TRMT1 cleavage and inactivation by Nsp5. (elifesciences.org)
  • The catalytic activity of aPC is greatly enhanced by the vitamin K-dependent cofactor protein S. (medscape.com)
  • At CST, we adhere to the Hallmarks of Antibody Validation™ , six complementary strategies for determining the specificity, sensitivity, and functionality of an antibody in any given assay. (cellsignal.com)
  • However, his experiments could not be reproduced by prominent immunochemists at the time, and, later, it became generally accepted that antibody specificity was not generated according to Pauling's and others' "instruction" template theories. (ucpress.edu)
  • While polyclonal antibodies are secreted by many different B cell clones and recognize multiple antigenic epitopes, monoclonals originate from a single B cell clone and are specific for just one epitope. (cellsignal.com)
  • Where polyclonal antibodies are purified directly from the serum of the immunized host, and monoclonals are purified from either hybridoma-derived tissue culture supernatant or ascites, recombinant antibodies are instead purified from the tissue culture supernatants of transfected host cell lines. (cellsignal.com)
  • Polyclonal antibodies were raised to CYP2C9 purified from human liver, and were then back-adsorbed against recombinant CYP2C19 coupled to a solid-phase support. (aspetjournals.org)
  • Chiral Anion Catalysis In 2007, they reported the first highly enantioselective transition metal-catalyzed reaction in which a chiral anion was solely responsible for the enantioinduction. (berkeley.edu)
  • For one of his first experiments, MacMillan needed an organic molecule that could catalyze a reaction that formed an iminium ion. (nordiclifescience.org)
  • He tested if proline could catalyze an aldol reaction, in which carbon atoms from two different molecules are bonded together. (nordiclifescience.org)
  • The apparent catalytic rate constant for hydrolysis of the substrate 1-hexyl sulfate by Bds1 is over 100 times lower than that of the reaction catalyzed by its bacterial homolog SdsA1. (bvsalud.org)
  • Studies on the effect of the molar ratio of the antibody to metalloporphyrin on the catalytic activity showed that a 1:1 complex was the most effective for the reaction. (ward-lab.ch)
  • The effect of salt (NaCl) on the reaction showed that electrostatic interaction between the antibody and the metalloporphyrin was important for the reaction. (ward-lab.ch)
  • The rate increase occurs because the catalyst allows the reaction to occur by an alternative mechanism which may be much faster than the non-catalyzed mechanism. (wikipedia.org)
  • Accordingly, manganese dioxide is said to catalyze this reaction. (wikipedia.org)
  • As a simple example occurring in the gas phase, the reaction 2 SO 2 + O 2 → 2 SO 3 can be catalyzed by adding nitric oxide . (wikipedia.org)
  • in yeast and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation. (biobool.com)
  • Alcohol dehydrogenase is responsible for catalyzing oxidation of primary and secondary alcohols to aldehydes and ketones, respectively, and also can effect the reverse reaction. (biobool.com)
  • They demonstrated that reductive elimination from diarylgold(III) complexes can be remarkably fast and subsequently applied their findings to a non-oxidative gold-catalyzed cross-coupling reaction. (berkeley.edu)
  • The reaction can be reversed - referred to as aerobic succinate-supported NAD+ reduction by ubiquinol - in the presence of a high membrane potential, but the exact catalytic mechanism remains unknown. (gowebamerica.com)
  • CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, including benzphetamine, ethylmorphine, chlorpromazine, imipramine and erythromycin. (ximbio.com)
  • Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for ADH and Avidin conjugated to 4 Horseradish Peroxidase (HRP) is added to each microplate well and incubated. (biobool.com)
  • The immunocytochemical staining was performed on paraffin sections with anti-CA15C3 (DAKO) as a primary antibody, with biotin-conjugated anti-mouse IgG (DAKO), and with peroxidase-conjugated streptavidin. (edrc2013.org)
  • What is a Recombinant Antibody and Why is it Important? (cellsignal.com)
  • Recombinant antibodies offer several key advantages compared to traditional antibodies. (cellsignal.com)
  • As such, recombinant antibodies are seeing increased use for scientific research, especially as a means of addressing the ongoing reproducibility crisis. (cellsignal.com)
  • What is a Recombinant Antibody? (cellsignal.com)
  • Recombinant antibodies are monoclonal, but their production involves in vitro genetic manipulation. (cellsignal.com)
  • Mammalian cell lines are most commonly used for recombinant antibody production, although cell lines of bacterial, yeast, or insect origin are also suitable. (cellsignal.com)
  • Because recombinant antibody production involves sequencing the antibody light and heavy chains, it is a highly controlled and reliable process. (cellsignal.com)
  • Recombinant antibodies are highly consistent from lot to lot, thereby ensuring reproducible experimental results. (cellsignal.com)
  • Unlike traditional methods for antibody production, recombinant approaches avoid the need to use animals. (cellsignal.com)
  • Regardless of whether an antibody is polyclonal, monoclonal or recombinant, it must always be properly validated in the intended application prior to experimental use. (cellsignal.com)
  • This remarkable activity is achieved by properly positioning the substrate in close proximity to the catalytic glutamate with very high pKa. (bvsalud.org)
  • The virtual lane view (left) shows the target bands (as indicated) at 1:10 and 1:50 dilutions of primary antibody. (cellsignal.com)
  • The corresponding electropherogram view (right) plots chemiluminescence by molecular weight along the capillary at 1:10 (blue line) and 1:50 (green line) dilutions of primary antibody. (cellsignal.com)
  • Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to ADH. (biobool.com)
  • This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global STT3A Antibody market with multiple angles, which provides sufficient supports to readers' strategy and decision making. (themarketreports.com)
  • Alkaline Phosphatase catalyzes the hydrolysis of phosphate esters yielding alcohols and phosphate. (scrippslabs.com)
  • L-proline, an amino acid, represents a class of biomimetic catalytic materials called organocatalysts. (aiche.org)
  • The amino acid located between the regulatory threonine and the catalytic histidine is highly conserved being serine in PPDK and cysteine in PEPS. (scirp.org)
  • A comparison of known PPDK and PEPS sequences revealed a high level of conservation of the amino acid sequence surrounding the catalytic histidine located within a central domain of the enzymes that was composed of GGXTS/CHAAI/VI/VA/SR with the regulatory threonine and catalytic histidine (shown in bold) conserved in all species. (scirp.org)
  • Anti-rabbit IgG (H+L), F(ab')₂ Fragment (Alexa Fluor ® 488 Conjugate) #4412 was used as a secondary antibody. (cellsignal.com)
  • Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. (abcam.com)
  • ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. (abcam.com)
  • In 1940, Linus Pauling proposed his template theory of antibody formation, one of many such theories that rejected Paul Ehrlich's selective theory of preformed "receptors" (antibodies), assuming instead a direct molding of antibody shapes onto that of the antigen. (ucpress.edu)
  • Antibodies that are able to catalyze the antigen for which they are specific are produced spontaneously by the immune system. (iisc.ac.in)
  • Through the description of the pro-coagulation factor VIII as a model target antigen for catalytic antibodies, we propose that catalytic antibodies have either a beneficial or a deleterious role depending on the physiopathological context. (iisc.ac.in)
  • The production of antibody-based immunoassays is necessary for the assessment of occupational exposure and the development of threshold limit values. (cdc.gov)
  • Catalytic immunoglobulins (Igs) both of the IgM and IgG isotypes have been detected in the serum of healthy donors, where they have been proposed to participate in the removal of metabolic waste and in the defense of the organism against invading pathogens. (iisc.ac.in)
  • 1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. (abbkine.com)
  • This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. (thermofisher.com)
  • After cloning the antibody genes into an expression vector, this is then transfected into an appropriate host cell line for antibody expression. (cellsignal.com)
  • In contrast, hybridoma-based systems for producing monoclonal antibodies are subject to genetic drift and instability, increasing the potential for lot-to-lot variability or loss of antibody expression. (cellsignal.com)
  • The extent to which these paths to EGFR activation will confer sensitivity to the tyrosine kinase inhibitors or to EGFR monoclonal antibodies is being explored. (aacrjournals.org)
  • We show that Bds1 shares a catalytic mechanism with SdsA1 in which the carbon atom of the sulfate ester is the subject of nucleophilic attack, rather than the sulfur atom, resulting in C-O bond lysis. (bvsalud.org)
  • However the non-catalyzed mechanism does remain possible, so that the total rate (catalyzed plus non-catalyzed) can only increase in the presence of the catalyst and never decrease. (wikipedia.org)
  • A phosphospecific antibody (anti-pACC) recognizes both ACC1 and ACC2 phosphorylated at these sites, and is a widely used marker for AMPK activation. (biomedcentral.com)
  • The following product was used in this experiment: COX7C Polyclonal Antibody from Thermo Fisher Scientific, catalog # 11411-2-AP. (thermofisher.com)
  • Moreover, the resultant two-electron oxidation form of GA-Fe is an excellent Fenton-like agent that can catalyze hydrogen peroxide decomposition into hydroxyl radical, finally triggering severe oxidative damage to tumors. (nature.com)
  • It is also sometimes difficult to prove that designer enzymes are truly catalytic on the basis of biochemical observations, and some exciting claims have been found to be flawed. (nature.com)
  • This antibody is specific to COX7C. (thermofisher.com)
  • Ag NPs were conjugated to antibodies with specific recognition for the corresponding target antigenic molecule, CRP, and used to catalyse the oxidation of TMB by H2O2. (strath.ac.uk)
  • In 1942, Pauling published his alleged success in producing specific artificial antibodies through experiments based on his 1940 theory. (ucpress.edu)
  • This antibody is specific for p85 cleaved form of PARP1. (abcam.com)
  • Immunocytochemical analyses was performed with specific antibodies to dJmj and tri-methylation at lysine 27 on histone H3 (H3K27me3). (sdbonline.org)
  • The specific activity of the PI 3-kinase immunoprecipitated with anti-phosphotyrosine antibody was 3-fold higher than that with anti-PI 3-kinase antibody. (edrc2013.org)
  • Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. (abcam.com)
  • A subset of the irradiated animals was handled with AEOL 10150, a potent catalytic scavenger of reactive oxygen and nitrogen species. (aabioetica.org)
  • Antibody 03-1, which was prepared by immunization with meso-tetrakis(4-carboxyphenyl)porphyrin (TCPP) conjugate, has been found to bind strongly to Mn(III)−TCPP and Fe(III)−TCPP complexes with dissociation constants of 4.1 × 10-7 and 1.5 × 10-7 M, respectively, although other monoclonal antibodies raised against TCPP did not bind to these TCPP−metal complexes. (ward-lab.ch)
  • The complexes of antibody 03-1 with Mn(III)−TCPP and Fe(III)−TCPP were found to catalyze oxidation of pyrogallol selectively. (ward-lab.ch)
  • The antibody−metalloporphyrin complexes are stable enough to show catalytic activity in the presence of an excess amount of H2O2. (ward-lab.ch)
  • Using antibodies, we demonstrated that the regulation of both Listeria monocytogenes PPDK and Escherichia coli PEP synthetase involves the phosphorylation of a threonine residue located close to the catalytic histidine residue. (scirp.org)
  • For continuous use, store undiluted antibody at 2-8°C for up to a week. (arigobio.com)
  • Growing patient base, launch of STT3A antibody drugs, increasing penetration of antibody drugs, and continuous regulation across the biopharmaceutical industry are the key factors driving the increase in STT3A antibody market revenue. (themarketreports.com)
  • An important area of this research involves using metal nanoparticles as artificial enzymes, known as nanozymes, which exhibit peroxidase-like activity enabling them to catalyse the oxidation of substrates such as 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2), giving a colorimetric response. (strath.ac.uk)
  • The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. (antibodies-online.com)
  • Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. (arigobio.com)
  • The SI derived unit for measuring the catalytic activity of a catalyst is the katal , which is quantified in moles per second. (wikipedia.org)
  • The productivity of a catalyst can be described by the turnover number (or TON) and the catalytic activity by the turn over frequency (TOF), which is the TON per time unit. (wikipedia.org)
  • More specifically, the catalytic domain is a zinc dependent deaminases domain and is essential for cytidine deamination. (embl.de)
  • Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. (thermofisher.com)
  • Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. (affbiotech.cn)
  • Tolbutamide is a sulfonylurea-type oral hypoglycemic agent whose action is terminated by hydroxylation of the tolylsulfonyl methyl moiety catalyzed by cytochrome P-450 (CYP) enzymes of the human CYP2C subfamily. (aspetjournals.org)
  • Experimental kinetics techniques are unable to pinpoint definitively the nature of the rate-enhancing interactions in the catalytic cycle. (aiche.org)
  • The pathophysiological relevance of catalytic antibodies thus remains an elusive issue. (iisc.ac.in)
  • In vitro methods for producing antibodies are amenable to large-scale production, meaning antibody availability is unlikely to become a limiting factor. (cellsignal.com)
  • Gamma-glutamyl carboxylase catalyzes carboxylation of Gla residues in the amino-terminal portion of the molecule. (medscape.com)
  • If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase. (thermofisher.com)
  • Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using EPRS antibody (67712-1-Ig, Clone: 1B7G2 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). (ptglab.com)
  • Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67712-1-Ig (EPRS antibody) at dilution of 1:1000 (under 10x lens). (ptglab.com)
  • Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67712-1-Ig (EPRS antibody) at dilution of 1:1000 (under 40x lens). (ptglab.com)
  • Richard Lerner shared the 2012 Prince of Asturias Award (now called the Princess of Asturias Award, which is often called the Spanish Nobel Prize, with Sir Gregory Winter for Professor Pieczenik's conception and their development of combinatorial antibody libraries. (wikipedia.org)
  • Traditional polyclonal and monoclonal antibodies are the product of normal B cell development and genetic recombination. (cellsignal.com)
  • Immunohistochemistry was performed using antibodies to phospho-AMPK (pAMPK), phospho-Acetyl Co-A Carboxylase (pACC) an established target for AMPK, HER2, ERα, and Ki67 on Tissue Micro-Array (TMA) slides of two cohorts of 117 and 237 primary breast cancers. (biomedcentral.com)
  • that is, maize leaf PDRP only catalyzes the regulation of PPDK and E. coli PSRP only catalyzes the regulation of PEPS. (scirp.org)