Her main research interests range over Coordination and Sustainable Chemistry, Homogeneous and Supported Catalysis, Green synthesis of metallic nanoparticles, Mechanochemistry (synthesis and catalysis) and Molecular Electrochemistry. (cienciavitae.pt)
Scaffolds1
Equipping the porous scaffolds with norbornene derivatives enables click-like ligation to introduce functional tetrazines, including a peptide-based organocatalyst. (boernerlab.de)
Oxidation2
Substrate specificity of catechol oxidase from Lycopus europaeus and characterization of the bioproducts of enzymic caffeic acid oxidation. (lookformedical.com)
I have successfully focused my research on the investigation of enzyme-catalysed reactions, their optimisation for applications in biotechnology and the synthesis of small molecules that mimic their structure and catalytic function ( i.e. biomimetics). (edu.au)
I advanced understanding of the contribution of metals to enzyme-catalysed reactions and employed state-of-the-art technologies ( e.g. cryo-EM, ancestral gene reconstruction) to develop enzyme inhibitors as leads for novel biocides (herbicides, fungicides, antibacterial compounds) and engineer enzymes with enhanced catalytic properties for industrial applications in the advanced manufacturing sector ( i.e. cell-free enzyme cascades, next-gen fertilisers). (edu.au)
Polymerization reactions of phenylacetylene derivatives are promoted by rhodium complexes within the discrete space of apo-ferritin in aqueous media. (ward-lab.ch)
Characterization1
Characterization of prepared derivatives showed that both methods lead to formation of crosslinked humic structures. (researchgate.net)
Nitrogen1
The aim of these studies has been to develop a much-needed general synthetic route to amino acids (and other amine derivatives) possessing a quaternary chiral centre alpha -to the nitrogen atom and in particular, alpha , alpha -disubstituted alpha -amino acids. (exeter.ac.uk)
Reaction2
An enzyme of the oxidoreductase class that catalyzes the reaction between catechol and oxygen to yield benzoquinone and water. (lookformedical.com)
Functionalized silica monoliths as well as silica particles in packed bed reactors have been applied in the enantioselective flow catalysis of the addition reaction between ß-nitrostyrene and n-butanal. (boernerlab.de)
Acid4
Mandelic acid is usually prepared by the acid-catalysed hydrolysis of mandelonitrile, which is the cyanohydrin of benzaldehyde. (wikipedia.org)
Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by monoamine oxidase and catechol-O-methyl transferase. (wikipedia.org)
The central theme of this methodology is the formation of alpha -aminoalkyl radicals from existing amino acid and alpha -amino alcohol derivatives by 1,5-hydrogen atom transfer and the subsequent trapping of these radicals with appropriate radicalphiles, thus generating quaternary centres with high efficiency and excellent stereocontrol. (exeter.ac.uk)
The results of cDNA cloning, peptide mapping, and amino acid sequencing of PPAE revealed that PPAE is synthesized as prepro-PPAE with 441 amino acid residues and is activated from pro-PPAE by cleavage of a peptide bond between Lys152 and Ile153. (lookformedical.com)
Group2
Substrates containing a -COOH group are inhibitors for catechol oxidase. (lookformedical.com)
She is Researcher (Core Member) at Centro de Química Estrutural (Coordination Chemistry and Catalysis Group) at Instituto Superior Técnico since 2009. (cienciavitae.pt)
Advanced oxidation processes (APOs) of aromatic compounds, particularly of phenol, yield several benzene derivatives, such as hydroquinone, catechol, and resorcinol, as intermediate metabolites of its transformation. (hindawi.com)
Ligands1
This work underscores that protein scaffolds are efficient chiral ligands for asymmetric catalysis. (ward-lab.ch)
Transfer1
These constructs were shown to catalyse the asymmetric transfer hydrogenation of aryl ketones in water with sodium formate as hydrogen donor at a much faster rate than the complexes alone. (ward-lab.ch)
Water1
PEROXYNITRITE iments involving trace metal catalysis, water was passed through layers consisting of a Dowex l-X8 anion-exchange resin, a 5OW-X8 cationexchange resin, Chelex 100 resin (Sigma), charcoal and then hydroxyquinolate glass beads (Pierce Chem. (docksci.com)
Metal1
Rather, metal ions appear to catalyze the heterolytic cleavage of peroxynitrite to form a nitroniumlike species (NOz+). (docksci.com)