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Catabolite RepressionEnzyme RepressionGalactosidasesCyclic AMP Receptor ProteinPhosphoenolpyruvate Sugar Phosphotransferase SystemGene Expression Regulation, BacterialOperonGlucoseCarbonGluconatesBacterial ProteinsRepressor ProteinsXyloseBacillus subtilisEscherichia coliReceptors, Cyclic AMPLactoseTryptophanaseMutationAllantoinSuccinatesArabinoseEnzyme InductionHistidine Ammonia-LyaseMolecular Sequence DataBase Sequencebeta-GalactosidaseGlycerolGenes, BacterialGenes, RegulatorCarbohydrate MetabolismGalactoseLac OperonCulture MediaNitrogenCyclic AMPMaltosepara-AminobenzoatesGene Expression Regulation, FungalTranscription, GeneticSaccharomyces cerevisiaePromoter Regions, GeneticKynurenineUrocanate HydratasePseudomonas putidaGATA Transcription FactorsLyasesGlycoside HydrolasesChlorophyllDNA-Binding ProteinsCarbohydrate EpimerasesDNA, BacterialAmmonia-LyasesSuccinic AcidFructose-Bisphosphatasealpha-AmylasesCellobioseGenes, Fungal4-Aminobenzoic AcidGenetics, MicrobialFructoseAmino Acid SequenceCloning, MolecularPlasmidsAldose-Ketose IsomerasesAspergillus nidulansAdipatesProtocatechuate-3,4-DioxygenaseFungal ProteinsEscherichia coli ProteinsRNA, BacterialTetralonesAcetate-CoA LigaseHexokinaseRegulonbeta-FructofuranosidaseMolecular BiologyGlucokinaseGalactokinasealpha-GlucosidasesMusaGenesAcetoin DehydrogenaseArbutinLactobacillus caseiAnaerobiosisBacillus megateriumAcetoinGlutamatesTiliaTranscription FactorsTryptophanPhosphoenolpyruvateArtificial Gene FusionCarbon IsotopesMutagenesis, InsertionalThiogalactosidesUrobilinogenAerobiosisKinetics

Activator proteinTranscriptionalProteinChlorophyllNitrogenMicrobialFavorMutantsGlucoseInhibitionBacteriaSystemicPhysiologicalColiUtilizationDependentLevelsPromoterRegulatoryModulating catabolite repressionRepression in bacteriaTryptophan catabolitesCatabolismEscherichiaTranscriptionTyrosinePathwayYeastToxicDescriptorUrinarySourceConditionsHighCaseCell

Activator protein1

• cAMP binds to catabolite activator protein (CAP) and together they will bind to a promoter sequence on the lac operon. (wikipedia.org)

Transcriptional2

• Transcriptomic and genomic analyses of 'mutualistic' E. coli lines revealed independent mutations that disrupted the carbon catabolite repression global transcriptional regulator system. (nature.com)
• At one end of this spectrum are " specialist " strategies that display high rates of growth in stable environments , with more stringent catabolite repression and slower transcriptional reprogramming. (bvsalud.org)

Protein3

• Gram positive bacteria such as Bacillus subtilis have a cAMP-independent catabolite repression mechanism controlled by catabolite control protein A (CcpA). (wikipedia.org)
• Note that E. coli has a similar cAMP-independent catabolite repression mechanism that utilizes a protein called catabolite repressor activator (Cra). (wikipedia.org)
• At the molecular level, it was found that replacement of glucose by starch has enhanced the relative expression level of ccpA encoding catabolite control protein A. Therefore, the repression of starch utilization by glucose could be probably relieved. (hindawi.com)

Chlorophyll1

• The chlorophyll catabolite, pheophorbide a, confers predation resistance in a larval tortoise beetle shield defense. (mpg.de)

Nitrogen1

• Specifically, because the chitin degradation product represents a carbon and a nitrogen source for fungi, complex regulatory mechanisms involving both nitrogen metabolism repression (NMR) and carbon catabolite repression (CCR) might be engaged. (lu.se)

Microbial2

• Here, we review emerging data suggesting that microbial tryptophan catabolites resulting from proteolysis are influencing host health. (ku.dk)
• Rewiring carbon catabolite repression for microbial cell factory. (illumina.com)

Favor1

• We exploit this natural heterogeneity to evolve a set of mutants that demonstrate how the frequency and duration of changes in carbon source can favor different carbon catabolite repression strategies . (bvsalud.org)

Mutants1

• The other mutants display less stringent catabolite repression , resulting in leaky expression of genes that are not required for growth in glucose . (bvsalud.org)

Glucose6

• The catabolite repression was first shown to be initiated by glucose and therefore sometimes referred to as the glucose effect. (wikipedia.org)
• However, the term "glucose effect" is actually a misnomer since other carbon sources are known to induce catabolite repression. (wikipedia.org)
• When glucose is available in the environment, the synthesis of β-galactosidase is under repression due to the effect of catabolite repression caused by glucose. (wikipedia.org)
• Absence of glucose will "turn off" catabolite repression. (wikipedia.org)
• A researcher that you collaborate with hypothesised that catabolite repression is dependent on the concentration of glucose in the environment. (nursingschoolessays.com)
• https://nursingschoolessays.com/wp-content/uploads/2019/12/logo1.png 0 0 admin https://nursingschoolessays.com/wp-content/uploads/2019/12/logo1.png admin 2021-02-27 12:33:40 2023-09-13 11:22:17 A researcher that you collaborate with hypothesised that catabolite repression is dependent on the concentration of glucose in the environment. (nursingschoolessays.com)

Inhibition1

• Catabolite inhibition: a general phenomenon in the control of carbohydrate utilization. (jax.org)

Bacteria1

• Carbon catabolite repression, or simply catabolite repression, is an important part of global control system of various bacteria and other microorganisms. (wikipedia.org)

Systemic2

• Tryptophan catabolites thus affect various physiological processes and may contribute to intestinal and systemic homeostasis in health and disease. (ku.dk)
• We engineered a calicheamicin conjugate that lacks the acid-labile hydrazine linker that leads to systemic release of a toxic catabolite. (aacrjournals.org)

Physiological1

• Our study provides the first global insight into the molecular physiological response of a multicellular fungus to carbon catabolite regulation and identifies several not yet known targets in a growth-controlled environment. (biomedcentral.com)

Coli2

• citation needed] Catabolite repression was extensively studied in Escherichia coli. (wikipedia.org)
• Each mutation reproduced the mutualistic phenotypes when introduced into wild-type E. coli , confirming that single carbon catabolite repression mutations can make E. coli an insect mutualist. (nature.com)

Utilization1

• The catabolite repression in this case is achieved through the utilization of phosphotransferase system. (wikipedia.org)

Dependent1

• GFAT1 expression is dependent on sufficient amounts of glutaminolysis catabolites particularly α-ketoglutarate, which are generated in an mTORC2-dependent manner. (princeton.edu)

Levels2

• Different levels of catabolite repression optimize growth in stable and variable environments. (bvsalud.org)
• Plasma levels of TRP catabolites were assessed using Ultra High Performance Liquid Chromatography-ElectroSpray-Ionization-Tandem Mass Spectrometry. (frontiersin.org)

Promoter1

• T7 RNA polymerase is expressed from the lacUV5 promoter, which is less sensitive to catabolite repression than the wt lac promoter. (neb.com)

Regulatory2

• One such wide-domain regulatory circuit, essential to all cells, is carbon catabolite repression (CCR): it allows the cell to prefer some carbon sources, whose assimilation is of high nutritional value, over less profitable ones. (biomedcentral.com)
• One such wide-domain regulatory circuit is carbon catabolite repression (CCR): it allows the preferred assimilation of carbon sources of high nutritional value over others [ 1 - 4 ]. (biomedcentral.com)

Modulating catabolite repression1

• Moreno R, Fonseca P, Rojo F (2011) Two small RNAs, CrcY and CrcZ, act in concert to sequester the Crc global regulator in Pseudomonas putida , modulating catabolite repression. (springer.com)

Repression in bacteria1

• Görke B, Stülke J (2008) Carbon catabolite repression in bacteria: many ways to make the most out of nutrients. (springer.com)

Tryptophan catabolites2

• The abnormal activation of the tryptophan catabolites pathway (TRYCATs) is observed in patients suffering from cerebrovascular disease, including stroke. (nih.gov)
• 26. Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites. (nih.gov)

Catabolism1

• catabolite: A product of catabolism. (openwetware.org)

Escherichia3

• citation needed] Catabolite repression was extensively studied in Escherichia coli. (wikipedia.org)
• Catabolite repression in Escherichia Coli - a comparison of modelling approaches. (mpg.de)
• A quantitative approach to catabolite repression in Escherichia coli. (mpg.de)

Transcription1

• Catabolite repression is considered to be a part of global control system and therefore it affects more genes rather than just lactose gene transcription. (wikipedia.org)

Tyrosine1

• SIGNIFICANCE STATEMENT Hepatic glutathione transferase zeta 1 (GSTZ1) is responsible for metabolism of the tyrosine catabolite maleylacetoacetate as well as the investigational drug dichloroacetate. (aspetjournals.org)

Pathway1

• KstR binds not to cholesterol itself, but to catabolites found early in the degradation pathway. (nih.gov)

Yeast1

• Yeast carbon catabolite repression. (microbiologyresearch.org)

Toxic1

• deoxythymidine (AMT), a toxic catabolite. (nih.gov)

Descriptor1

• Catabolite Repression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)

Urinary2

• Decreased urinary excretion of biotin and its catabolites is an early indicator of biotin deficiency. (medscape.com)
• 2017. Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial. . (oregonstate.edu)

Source1

• Catabolite repression allows microorganisms to adapt quickly to a preferred (rapidly metabolizable) carbon and energy source first. (wikipedia.org)

Conditions1

• However, the electroneutral antiport of fumarate for succinate during anaerobic fumarate respiration has been demonstrated, and both permeases are induced under anaerobic conditions and are subject to catabolite repression. (tcdb.org)

High1

• The increased residuals lead to high catabolite repression. (openwetware.org)

Case1

• The catabolite repression in this case is achieved through the utilization of phosphotransferase system. (wikipedia.org)

Cell1

• There are different catabolite-specific EIIA in a single cell, even though different bacterial groups have specificities to different sets of catabolites. (wikipedia.org)