The importance of sleep and suggestions about its physiological role have been better documented as a negative, by what happens without sleep, since prolonged sleep deprivation (SD) or sleep restriction adversely influences metabolic processes ( Knutson, 2007 ), general emotional and physical health ( Haack and Mullington, 2005 ), and neurocognitive behavior ( Lim and Dinges, 2008 ). (jneurosci.org)
Predicted to be involved in carbohydrate metabolic process and glycerol-3-phosphate catabolic process. (mcw.edu)
The module aims to deepen your knowledge of the important roles enzymes, hormones and chemical reactions play in the regulation of metabolism and considers multiple metabolic and biochemical pathways involved in the process of energy turnover and storage, metabolic signals/pathways involved in adaptation, and the interaction of macro/micro nutrients with these systems. (ncl.ac.uk)
Ontology2
Gene ontology functional enrichment analysis revealed twenty eight biological processes and 10 molecular functions associated with cognitive impairment. (ijpsonline.com)
GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code. (yeastgenome.org)
Catabolism1
Anabolic processes, which include the synthesis of such cell components as carbohydrates , proteins , and lipids , require energy in the form of energy-rich compounds (e.g., adenosine triphosphate ) that are produced during breakdown processes ( see catabolism ). (britannica.com)
Biosynthetic1
Together, these results suggest that sleep-induced surge in ATP and the decrease in P-AMPK levels set the stage for increased anabolic processes during sleep and provide insight into the molecular events leading to the restorative biosynthetic processes occurring during sleep. (jneurosci.org)
Breakdown2
The α -amino group is a catabolic key that protects amino acids from oxidative breakdown. (medscape.com)
It is used also with drugs and chemicals for catabolic changes (breakdown of complex molecules into simpler ones). (bvsalud.org)
Intracellular2
Autophagy is an intracellular catabolic pathway in which cellular constituents are engulfed by autophagosomes and degraded upon autophagosome fusion with lysosomes. (nature.com)
Spermiogenesis is the intracellular clearance process for male gametes. (frontiersin.org)
Anabolic processes3
In growing cells, anabolic processes dominate over catabolic ones. (britannica.com)
Furthermore, the changes in ATP exhibit reciprocity with the phosphorylated state of the cellular energy sensor, phosphorylated AMP-activated protein kinase (P-AMPK), thus supporting the induction of anabolic processes during sleep. (jneurosci.org)
For anabolic processes (conversion of small molecules into large), BIOSYNTHESIS is used. (bvsalud.org)
Protein2
Protein posttranslational modifications (PTMs) play key roles in a variety of protein activities and cellular processes. (hindawi.com)
PTMs are involved in many protein activities and cellular processes, such as protein folding, stability, conformation, and some significant regulatory mechanisms [ 1 ]. (hindawi.com)
Annotations2
Link to all direct and indirect annotations to demethylkotanin catabolic process. (planteome.org)
Manually curated GO annotations reflect our best understanding of the basic molecular function , biological process , and cellular component for this gene product. (yeastgenome.org)
Degradation5
In this catabolic process, matrix metalloproteases and cytokines also cause degradation of cartilage. (medscape.com)
Genes required for degradation of and growth on the carbon source pectin were down-regulated, whereas transcripts involved in redox processes were up-regulated. (frontiersin.org)
Autophagy/macroautophagy is a lysosome-dependent catabolic process characterized by increased formation of double-membrane autophagosomes for the sequestration of cytoplasmic components and subsequent degradation after autophagosome fusion with lysosomes 1 , 2 . (nature.com)
Abiotic hydrolysis, photodegradation, and biodegradation are all important processes for the transformation and degradation of chlorpyrifos. (cdc.gov)
Although a large amount of chlorpyrifos is used in various environments (see Chapter 4), levels of general exposure are mediated by its limited mobility and persistence, and by environmental degradation processes. (cdc.gov)
Oxidative1
Answer: Processes that occur under aerobic conditions such as- Citric Acid Cycle, Oxidative Phosphorylation, and Glycolysis. (flashcardmachine.com)
Activates1
This elevated myoplasmic calcium activates acute cellular catabolic processes that cascade to the malignant hyperthermia crisis. (nih.gov)
Gluconeogenesis3
We can go weeks without food through a process known as gluconeogenesis. (robbwolf.com)
Gluconeogenesis is a catabolic process initiated by cortisol. (robbwolf.com)
Your liver converts amino acids to glucose that your brain and body can use by a process called gluconeogenesis. (cathe.com)
Urea1
We suggest that a feedback relationship exists between the major end catabolic products (creatinine and blood urea nitrogen) and thyroid hormone serum levels. (who.int)
Proteins3
Autophagy is the main cellular process responsible for degrading defective organelles and long-lived proteins. (frontiersin.org)
These include proteins that are constituents of musculoskeletal tissue and are produced through catabolic or repair processes, proteins associated with inflammatory changes, and indicators of immune or autoimmune processes. (cdc.gov)
Biological process GO terms and their p-values for co-expressed proteins. (lu.se)
Enzyme4
Enzyme function and hormonal coordination of anabolic and catabolic processes for the control of energy turnover. (ncl.ac.uk)
This is accomplished in the process of producing adenosine diphosphate (ADP) from ATP by the enzyme glutamine synthetase, which is responsible for mediating the formation of glutamine from an amino group. (medscape.com)
In lysosomal storage disorders, the deficiency of a specific lysosomal enzyme interrupts the normal catabolic pathway, resulting in the cellular accumulation of substrates ordinarily degraded by that enzyme. (medscape.com)
This enzyme begins the process of breaking down proline by starting the reaction that converts proline to pyrroline-5-carboxylate. (medlineplus.gov)
Functions2
The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. (yeastgenome.org)
The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved. (yeastgenome.org)
Lipid1
In C. elegans, paf-1 is involved in lipid catabolic process. (wormbase.org)
Cytoplasm1
There was not an obvious shedding process of unnecessary cytoplasm during spermiogenesis although, the cell size of the maturing spermatozoon was reduced. (frontiersin.org)
Biological processes1
Evidence for the opportunity to influence these biological processes even before surgery was provided in a randomized clinical trial by Christian Lattermann, MD, at the University of Kentucky, Lexington, and colleagues. (medscape.com)
Upstream1
Predicted to act upstream of or within arginine catabolic process. (nih.gov)
Depends1
According to most evidence, whether cardio is catabolic, depends on how much cardio you do and how you feed your body. (cathe.com)
Stimuli2
Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process. (adventuresofaglutenfreemom.com)
The autonomic nervous system receives input from parts of the central nervous system (CNS) that process and integrate stimuli from the body and external environment. (msdmanuals.com)
Mechanisms1
With the development of high-throughput sequencing technology, gene mutation detection has become another important resource to investigate regulatory mechanisms and cellular processes. (hindawi.com)
Signal1
This is a signal that you've entered a catabolic state. (cathe.com)
Description1
Therefore, in this review, we avoid a lengthy repetition of the description of autophagy and cell death processes and focus on the death-promoting roles of autophagy and the intertwined connection between autophagy and apoptosis. (nature.com)
Response1
phenylalanine catabolic process and response to ABA. (bvsalud.org)
Major1
Autophagy serves as a major cytoprotective process by maintaining cellular homeostasis and recycling cytoplasmic contents. (nature.com)
Control1
The healing requires biological and biomechanical processes that we can influence but not control. (medscape.com)
Normal2
The normal process of removing the amino group present on all amino acids produces ammonia. (medscape.com)
Under normal circumstances, both the liver and the brain generate ammonia in this removal process, substantially contributing to total body ammonia production. (medscape.com)