Cases of urticaria pigmentosa. Medical search. Frequent questions

Urticaria pigmentosa (also known as generalized eruption of cutaneous mastocytosis (childhood type): 616 ) is the most common form of cutaneous mastocytosis. (wikipedia.org)
Most treatments for mastocytosis can be used to treat urticaria pigmentosa. (wikipedia.org)
Types of cutaneous mastocytosis include solitary mastocytoma, diffuse erythrodermic mastocytosis, paucicellular mastocytosis (also termed telangiectasia macularis eruptiva perstans [TMEP]), and urticaria pigmentosa (UP). (medscape.com)
Urticaria pigmentosa is a type of mastocytosis, a term applied to a group of disorders in which mast cells accumulate within tissue. (consultant360.com)
The 3 major types of mastocytosis in childhood are urticaria pigmentosa, solitary mastocytoma of the skin, and diffuse cutaneous mastocytosis. (consultant360.com)
Systemic mastocytosis can occur in up to 2% of patients with hereditary urticaria pigmentosa and must be considered in the presence of evidence of systemic involvement such as flushing, tachycardia, hypotension, diarrhea, vomiting, symptoms of peptic ulcer, and even splenomegaly and hepatomegaly. (consultant360.com)
In most cases, there is no family history of mastocytosis. (dermnetnz.org)
Recent studies in single cases or small case-series have shown promising results for omalizumab in mastocytosis (6-8). (nih.gov)
With the exception of pure cutaneous mastocytosis (usually urticaria pigmentosa), indolent SM affecting bone marrow and skin is the most common subvariant of mastocytosis. (bmj.com)
See Systemic Mastocytosis, Mastocytosis & Urticaria Pigmentosa, and Anaphylaxis. (medscape.com)
The main application of urinary NMH measurement is in the diagnosis and monitoring of mast-cell disorders, such as mastocytosis (systemic and localized urticaria pigmentosa), anaphylaxis, and other severe systemic allergic reactions. (medscape.com)
Serum tryptase is a highly specific marker for mastocytosis, being increased in more than 83% of cases. (medscape.com)
Urticaria pigmentosa (maculopapular mastocytosis): many red-brown, maculopapular lesions, with variable flushes and pruritus (most common form). (cyberderm.net)
Cutaneous mastocytosis (urticaria pigmentosa and diffuse cutaneous mastocytosis) shows a disseminated appearance on the entire body. (cyberderm.net)
The 2016 updated current WHO classification of mastocytosis identifies 3 forms of cutaneous mastocytosis: urticaria pigmentosa, diffuse cutaneous mastocytosis, and mastocytoma. (cyberderm.net)
Some affected individuals have a skin condition called urticaria pigmentosa (also known as maculopapular cutaneous mastocytosis), which is characterized by raised patches of brownish skin that sting or itch when touched. (medlineplus.gov)
When following patients with mastocytosis - whether classical urticaria pigmentosa in children or adult mastocytosis - I usually ask a directed review of systems, focusing on flushing, palpitations, and gastrointestinal symptoms. (aad.org)
Dan DeAngelo, MD, PhD, presents the case of a 75-year-old man with systemic mastocytosis and reviews WHO diagnostic criteria. (onclive.com)
This is a case report of a 52-year-old lady, with systemic mastocytosis, who presented with severe chronic back ache and no other clinical features. (manipal.edu)
We report the case of a 69-year-old female with systemic mastocytosis, diagnosed based on widespread pigmented papules and macules, elevated serum tryptase levels and confirmatory skin and bone marrow biopsy, on a background of osteoporosis. (bioscientifica.com)
This case highlights the complexities of systemic mastocytosis-related bone disease and the interplay of numerous mediators contributing to a phenotype of both increased bone resorption and formation. (bioscientifica.com)
Systemic mastocytosis should be suspected in patients presenting with not only cutaneous symptoms suggestive of mast cell degranulation such as anaphylaxis, flushing or urticaria but also unexplained osteoporosis and gastrointestinal and constitutional symptoms. (bioscientifica.com)
Doctors can diagnose urticaria pigmentosa (cutaneous mastocytosis, see below) by seeing the characteristic lesions which are dark-brown and fixed. (the-medical-dictionary.com)
Mastocytosis represents a spectrum of disease ranging from urticaria pigmentosa, an increase of dermal mast cells, to systemic mastocytosis involving bone marrow, skeleton, gastrointestinal canal, liver and spleen. (the-medical-dictionary.com)
The aim of this study was to compare patients with systemic mastocytosis and with urticaria pigmentosa in regard to bone density and biochemistry. (the-medical-dictionary.com)
Six patients had systemic mastocytosis and ten had urticaria pigmentosa. (the-medical-dictionary.com)
In rare cases, the disease may remain active through adolescence as a systemic adult mastocytosis. (nih.gov)
Skin diseases such as urticaria pigmentosa and cutaneous mastocytosis are also very common in the specimens of this breed. (catbreedshouse.com)
Urticaria pigmentosa is found in most patients with mastocytosis. (clinicaladvisor.com)
I'd love to know if this is the case just for those of us with histamine intolerance, mast cell activation and mastocytosis, or if it applies to the public in general. (healinghistamine.com)
Cutaneous mastocytosis is the most successive type of pole cell infection, representing 90% of cases. (md-fm.com)
Numerous people with foundational mastocytosis foster urticaria pigmentosa, portrayed by raised areas of earthy skin that sting or tingle when contacted or when the temperature changes. (md-fm.com)

It can be seen as a solitary finding, as in the solitary mastocytoma, or it can result in widespread cutaneous disease, as in urticaria pigmentosa. (pediagenosis.com)
While the majority of cases present as a solitary cutaneous nodular lesion, the eye is the most frequent extracutaneous site of JXG. (eyewiki.org)

Systemic mast cell disease: analysis of 58 cases and literature review. (medigraphic.com)
1 Hereditary urticaria pigmentosa generally presents after 1 year of age, the lesions do not spontaneously resolve, and systemic involvement may be seen over time. (consultant360.com)
Cold urticaria can be associated with anaphylaxis if there is systemic cold exposure (eg, aquatic activities). (empendium.com)
In most pediatric cases, the disease is limited to the skin, but it can be associated with systemic symptoms due to the release of mediators from mast cells, even when there is no systemic infiltration. (nih.gov)

Several factors can worsen the symptoms of urticaria pigmentosa:[citation needed] Emotional stress Physical stimuli such as heat, friction, and excessive exercise Bacterial toxins Venom Eye drops containing dextran NSAIDs Alcohol Morphine The classification of NSAIDs can be disputed. (wikipedia.org)
Treatment of this urticaria pigmentosa generally is supportive to control the symptoms. (consultant360.com)
In a majority of cases, the pathophysiology of these symptoms is not known but could be linked to mast cell infiltration, mast cell mediator release, or both. (aad.org)
It presents with non-specific symptoms like urticaria pigmentosa, unexplained flushing, hypotension and abdominal cramps, which may lead to a misdiagnosis, if there is no high index of clinical suspicion. (manipal.edu)
In many cases-particularly if the tumors are small-a person with a GIST may experience no symptoms at all. (carygastro.com)

Urticaria pigmentosa may manifest as reddish plaque-like lesions on the skin. (msdmanuals.com)

The mast cell-activating signals in urticaria are ill defined and likely to be heterogeneous and diverse (IgE-mediated Type I-reaction, non specific histamine liberators, activation of complement, autoimmune mediated urticaria - IgG against IgE or against high affinity IgE-receptor and IgE against autoantigens, as well as other poorly understood mechanisms). (cyberderm.net)
Urticaria results from the release of histamine, bradykinin, kallikrein, and other vasoactive substances from mast cells and basophils in the superficial dermis, resulting in intradermal edema caused by capillary and venous vasodilation and occasionally caused by leukocyte infiltration. (msdmanuals.com)
In my own case it has been hard to distinguish whether it's the stress causing the illness or the histamine causing the stress. (healinghistamine.com)

Written information about the risk of anaphylaxis +/- adrenaline syringe in high risk cases. (cyberderm.net)
In extreme cases they could cause anaphylaxis, that is the maximum severity of the hypersensitive reactions. (usa-good.com)
Acute urticaria must be differentiated from anaphylaxis . (empendium.com)
Urticaria needs to be differentiated from other medical conditions where wheals, angioedema, or both can occur, e.g. anaphylaxis, autoinflammatory syndromes, urticarial vasculitis, orbradykinin-mediated angioedema including hereditary angioedema (HAE). (cyberderm.net)

Based on findings from the history and physical examination, the boy received a diagnosis of urticaria pigmentosa. (consultant360.com)
The diagnosis of the skin disease was based on the clinical criteria for urticaria pigmentosa, e.g. multiple reddish brown maculae urticating after rubbing. (the-medical-dictionary.com)
The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. (empendium.com)
Methods report on the development of the 2013 revision and update of the EAACI/GA2 LEN/EDF/WAO guideline for the definition, classification, diagnosis, and management of urticaria. (empendium.com)
The diagnosis and management of acute and chronic urticaria: 2014 update. (empendium.com)
Standardized provocation testing to diagnose chronic inducible urticaria are required for an accurate diagnosis. (cyberderm.net)

It's true Idiopathic Urticaria (the medical term for Hives) isn't usually fatal. (str8onebehealthy.com)
This photo shows a positive ice cube test in a patient with idiopathic cold-induced urticaria. (msdmanuals.com)

This photo shows solar urticaria in a woman who had been wearing a tank top. (msdmanuals.com)

Yes, I want to finally get rid of my urticaria/angioedema skin condition. (str8onebehealthy.com)
So, What REALLY Causes Urticaria and Angioedema? (str8onebehealthy.com)
Urticaria is a condition characterized by transient wheals (hives), angioedema, or both. (empendium.com)
Urticaria is a group of diseases characterized by the development of wheals (hives), angioedema (see chapter 1.1.2), or both. (cyberderm.net)
Urticaria may be associated with angioedema: Pronounced erythematous or skin colored swelling of the lower dermis and subcutis or mucous membranes. (cyberderm.net)
Acute spontaneous urticaria: Occurrence of spontaneous wheals, angioedema or bothfor less than 6 weeks. (cyberderm.net)

Acute urticaria is much more common than chronic urticaria. (diseasesdic.com)
Acute urticaria is most common in children and is more common in women than in men, particularly in the 30-60 age range. (diseasesdic.com)
f) Causes of acute urticaria (see above). (empendium.com)
For non-acute urticaria, around 0.1-0,6% in the general population. (cyberderm.net)
Acute urticaria: Does not require a diagnostic workup, as it is usually self-limiting. (cyberderm.net)

c) Delayed pressure urticaria , caused by pressure on the skin. (empendium.com)

At least one clinical study suggested that nifedipine, a calcium channel blocker used to treat high blood pressure, may reduce mast cell degranulation in patients with urticaria pigmentosa. (wikipedia.org)
250 Clinical Cases covers a wide variety of conditions, providing in-depth insights into the most relevant topics, classified by system. (elsevierhealth.com)
The clinical manifestations associated with duplication at the end of 7p are mostly delineated and in most cases result from in inheritance of parental chromosome harbouring a balanced translocation. (jpai.in)
The spectrum of clinical manifestations of different urticaria subtypes is very wide. (cyberderm.net)

included a patient with symptomatic urticaria pigmentosa who responded to nifedipine taken three times daily. (wikipedia.org)

The definition, diagnostic testing, and management of chronic inducible urticarias - The EAACI/GA(2) LEN/EDF/UNEV consensus recommendations 2016 update and revision. (empendium.com)

The condition typically runs a benign course in children, and most cases spontaneously remit over a few years and then disappear at about the time of puberty. (pediagenosis.com)

In some forms of urticaria the lesions may be papular (e.g. cholinergic urticaria). (cyberderm.net)

Urticaria pigmentosa occurs in 2 distinct types, hereditary and nonhereditary. (consultant360.com)
The hereditary type is rare and accounts for less than 2% of cases of childhood urticaria pigmentosa. (consultant360.com)

An acute urticarial lesion that is healing with pigmentation raises the suspicion for urticaria pigmentosa. (consultant360.com)

Bone marrow findings in adult patients with urticaria pigmentosa. (medigraphic.com)
Thirteen cases of SM and three of lymphoplasmacytic immunocytoma with predominant focal bone marrow infiltration were investigated. (bmj.com)

citation needed] Urticaria pigmentosa is a rare disease, affecting fewer than 200,000 people in the United States. (wikipedia.org)
Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history. (myupchar.com)
Adult-onset urticaria pigmentosa is a more chronic disease that rarely remits. (pediagenosis.com)
8 cases (27%) developed fulminant hepatic failure out of which 2 cases had co-infection with dengue, 1 case had a history of consumption of nimesulide and 1 case had chronic liver disease & 7 cases (25.9%) succumbed to death. (jpai.in)
Urticaria is a mast cell-driven disease. (cyberderm.net)
In some cases, it is associated with a clonal hematologic non-mast-cell lineage disease, such as a myelodysplastic or myeloproliferative disorder. (nih.gov)
JXG has been associated with neurofibromatosis 1, Niemann- pick disease and urticaria pigmentosa. (eyewiki.org)

Most MCs in SM cases constantly coexpressed tryptase, CD25, and CD117. (bmj.com)

A total 59 cases were enrolled in the study in which infection was suspected at the time of admission based on the category in IMNCI/FIMNCI for suspicion of infection. (jpai.in)

citation needed] There are no permanent cures for urticaria pigmentosa. (wikipedia.org)
In many cases of urticaria it cures by its own. (diseasesdic.com)

Chronic Spontaneous Urticaria: Limited investigations are recommended: FBC, automated chemistry, CRP and/or ESR. (cyberderm.net)

The localized form usually occurs in the skin as urticaria pigmentosa. (medscape.com)

The prevalence rate for chronic urticaria has been estimated as 1-5 per 1,000. (diseasesdic.com)

If hives appear, it most likely signifies the presence of urticaria pigmentosa. (wikipedia.org)

In assessing the diagnostic value of the test, one must carefully differentiate between the treated and untreated cases of syphilis. (stdpioneer.org)
It can never be considered diagnostic in the same way as one would be justified in assuming a strong positive reaction in the untreated case, as a definite evidence of syphilis. (stdpioneer.org)
Because there are no definitive diagnostic tests for urticaria, evaluation largely relies on history and physical examination. (msdmanuals.com)

Well, this may sound revolutionary, but after my research, I came to the following conclusion: "Urticaria sufferers are not allergic to ANYTHING! (str8onebehealthy.com)

However, nifedipine has never been approved by the FDA for treatment of urticaria pigmentosa. (wikipedia.org)
In our case, despite the standard application of an increased dose of different H1-receptor antagonists combined with topical steroid preparations, the patient showed no response to treatment and suffered a significant adverse influence on her quality of life and daily activities. (nih.gov)
No great extent and to intensive treatment, the wassermann reaction as " since this case vi. (dwellbycheryl.com)
But that a similar case is under treatment, vesicular nuclei. (dwellbycheryl.com)
In cases of razor bumps, the primary goal of treatment is to reduce the surrounding inflammation and decrease your risk of infection. (healthline.com)
This is the usual dosage recommended in most common treatment cases. (myupchar.com)
In treated cases it is important to remember the interval which has elapsed since the last treatment was given. (stdpioneer.org)
The Plantar warts are harmless mostly and also go away without treatment but in case if it persists and starts spreading the medical attention is needed. (drvikram.com)

Urticaria pigmentosa is the most common form and is characterized by oval or round red-brown macules, papules, or plaques ranging in number from a few to thousands (see images below). (medscape.com)
This unique book presents a wealth of information on common presentations and illnesses, presented as medical case studies. (elsevierhealth.com)
Cases are accompanied by common viva voce examination questions as well as more advanced level questions that will help the reader develop a deeper understanding. (elsevierhealth.com)

The infant shown here has profuse papulonodular and plaque lesions of urticaria pigmentosa. (msdmanuals.com)

Mastocytosis32

Cutaneous2

Systemic4

Symptoms5

Lesions on the skin1

Histamine3

Anaphylaxis4

Diagnosis6

Idiopathic2

Solar urticaria1

Angioedema6

Acute urticaria5

Pressure urticaria1

Clinical4

Symptomatic1

Definition1

Puberty1

Cholinergic1

Hereditary2

Lesion1

Bone marrow2

Disease7

Tryptase1

Suspicion1

Cures2

Spontaneous1

Occurs1

Prevalence1

Hives appear1

Diagnostic3

Allergic1

Treatment8

Common3

Infant1