• We report the case of a young adult who presented with a painful foot due to chondroblastoma associated with an aneurismal bonecyst.Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur. (aku.edu)
  • Chondroblastoma of the Distal Femur in an Adolescent. (ucsd.edu)
  • This case report describes the unusual occurrence of a flexor digitorum profundus avulsion secondary to an enchondroma of the distal phalanx of the middle finger. (koreamed.org)
  • Instillation in intralesional tumor excision of chondroblastoma, osteoclastoma and enchondroma. (jbstjournal.com)
  • Although the exact etiology of chondroblastoma remains uncertain, the presentation, appropriate evaluation, and treatment of patients with the condition have been well described. (medscape.com)
  • The etiology of chondroblastoma is uncertain, as there is no specific characteristic abnormality or chromosomal breaking point observed, despite cytogenetic abnormalities being highly specific for some tumors. (wikipedia.org)
  • This case describes a teenage girl who returns one year later with recurrent osteochondroma. (faoj.org)
  • Chondroblastoma of the cuboid with an associated aneurysmal bone cyst:" by Yasir J Sepah, masood umer et al. (aku.edu)
  • Association of chondroblastoma with aneurysmal bone cyst is well documented however this association has only once been reported in the cuboid.Imaging techniques should be supplemented with an open biopsy for the final diagnosis. (aku.edu)
  • These include chondroblastoma, giant cell tumor (GCT) and aneurysmal bone cyst. (jept.ir)
  • A study of 49 cases of histopathologically confirmed secondary aneurysmal bone cysts found giant cell tumor and chondroblastoma to be the most frequent primary lesions. (medscape.com)
  • In contrast, treatment of aneurysmal bone cyst by external beam radiotherapy is associated with occasional cases of myelopathy (4) and radiation-induced sarcomas (4, 6, 7). (symptoma.com)
  • These include 9 of 135 cases initially treated by extended curettage and bone cement and 18 of 88 cases initially treated by curettage and bone graft. (jbstjournal.com)
  • Both Indian Hedgehog/parathyroid hormone-related protein (IHh/PtHrP) and fibroblast growth factor (FGF) signaling pathways, important for development of the epiphyseal growth plate, are active in chondroblastoma leading to greater proliferation among the cells in the proliferating/pre-hypertrophic zone (cellular-rich area) versus the hypertrophic/calcifying zone (matrix-rich area). (wikipedia.org)
  • Additionally, rare prevalence of chondroblastoma in intra-membranous ossification suggests a close relationship with growth plate cartilage. (wikipedia.org)
  • In chondroblastoma, growth signaling molecules may be present due to the pre-pubertal signaling network as well as cartilage growth. (wikipedia.org)
  • The work of Aigner et al suggests that chondroblastoma should be reclassified as a bone-forming neoplasm versus a cartilaginous neoplasm due to the presence of osteoid matrix, type I collagen, and absence of true cartilage matrix (collagen II). (wikipedia.org)
  • Chondroblastoma is a benign tumor of immature cartilage cells which primarily occurs in the epiphysis of long bones in the second decade of life with slight male preponderance. (faoj.org)
  • Histopathology of specimen observed chondroblasts proliferation with areas of mature cartilage , and giant cells confirming intrasynovial chondroblastoma . (bvsalud.org)
  • 9,10,12 Although signs of periosteal osteosarcoma may appear subtle on knee radiographs, magnetic resonance imaging (MRI) typically reveals a large, extraosseous soft-tissue mass with intramedullary invasion in some cases. (appliedradiology.com)
  • The differential diagnosis includes simple bone cyst, ABC (primary or secondary), chondroblastoma, giant cell tumor (GCT), osteosarcoma, ossifying hematoma or pseudotumor of hemophilia . (symptoma.com)
  • Chondroblastoma-like osteosarcoma: a clinicopathological and molecular study of a rare osteosarcoma variant. (cdc.gov)
  • Chondroblastoma of proximal tibia diagnosed by arthroscopy-guided biopsy: a case report. (bvsalud.org)
  • [ 4 ] They considered the term chondroblastoma to be a misnomer and believed that the tumor should be reclassified as a bone-forming neoplasm. (medscape.com)
  • However, Edel et al found that collagen II, a marker for mature chondrocytes, was expressed in chondroblastoma, supporting the chondroid nature of the neoplasm. (wikipedia.org)
  • The results of Romeo and colleagues favor the view of Edel et al of chondroblastoma being cartilaginous in nature but recognize that any definitive determinations regarding the origin of this neoplasm are not possible because of the plasticity of mesenchymal cells when set into different microenvironments and static approaches used in literature. (wikipedia.org)
  • Chondroblastoma considered a rare form of osseous neoplasm contributes less than 1% of all bone tumours. (bvsalud.org)
  • Diagnostic arthroscopy is a rare but essential modality in such cases due to better visuals, complete tumour excision, and combination with adjuvant therapies . (bvsalud.org)
  • Most cases are treated surgically, most commonly with excision of the mass and corrective osteotomy. (medscape.com)
  • Romeo et al have observed chondroblastoma neoplasms to be composed of mesenchymal cells that have completed normal chondrogenesis along with the production of osteoid and collagen I that could be the result of transdifferentiation of chondrocytes towards osteoblasts. (wikipedia.org)
  • A chondroblastoma is a rare, usually benign, tumor of bone that accounts for approximately 1% of all bone tumors. (medscape.com)
  • In the United States, chondroblastoma accounts for approximately 1% of all bone tumors. (medscape.com)
  • Chondroblastoma is very uncommon, accounting less than 1% of all bone tumors. (wikipedia.org)
  • [ 1 ] Locally aggressive stage III benign tumors extend beyond natural borders and often require en bloc resection for cure. (medscape.com)
  • [ 5 ] On examination of about 15 examples of GCTTS and PVNS, large areas of chondroid differentiation were noted that could not be distinguished from chondroblastoma of bone by either histologic or electron microscopic features. (medscape.com)
  • The researchers theorized that chondroblastoma of bone stems from an intraosseous proliferation of tendon sheath cells that have a predilection for chondroid formation. (medscape.com)
  • Trevor's disease: up-to-date review of the literature with case series. (medscape.com)
  • 7 ] In chondroblastoma of the foot and ankle, recurrence is common, and outcomes are generally worse than in other locations in the skeleton. (faoj.org)
  • Most cases are treated surgically but recurrence is common. (medscape.com)
  • There are two opposing views on the nature of chondroblastoma, one favoring an osseous origin and the other favoring a cartilaginous origin. (wikipedia.org)
  • Joshi PV, Lele V, Gandhi R. An unusual case of extra-osseous accumulation of a bone scan tracer in a renal calculus - demonstration by SPECT-CT. (bankersvascular.com)
  • There have been reports of abnormalities in chromosomes 5 and 8, as well as of p53 mutations, in patients with chondroblastoma. (medscape.com)
  • Approximately 92% of patients presenting with chondroblastoma are younger than 30 years. (medscape.com)
  • Chondroblastoma shows a predilection towards the male sex, with a ratio of male to female patients of 2:1. (wikipedia.org)
  • it was found that the average duration of symptoms for patients with chondroblastoma was about 20 months, ranging from 5 weeks to 16 years. (wikipedia.org)
  • Furthermore, it is most often observed in young patients that are skeletally immature, with most cases diagnosed in the second decade of life. (wikipedia.org)
  • Giantcell tumor of bone: analysis of two hundred and eight cases in Chinese patients. (jept.ir)
  • Recurrence was found in 27 patients of 225 cases of GCTB treated by extended surgical curettage. (jbstjournal.com)
  • Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or apophyses of long bones. (wikipedia.org)
  • Chondroblastoma is a rare tumor and is common in people of between the ages of 10 to 20 years old. (orthowestfl.com)
  • I had to undergo an surgery for a Chondroblastoma, a rare tumor in my skull base and jugular foramen. (kcprf.org)
  • Case Presentation: The authors present a case report of GCT of patella in a 16-year old child. (jept.ir)
  • Giant cell tumor of patella: A case report and review of literature', Journal of Emergency Practice and Trauma , 6(1), pp. 47-49. (jept.ir)
  • The present case report describes a 10-year-old female patient with a delayed diagnosis of patella osteomyelitis. (hindawi.com)
  • In 1829, Thirion described the first case of acute patella osteomyelitis [ 3 ]. (hindawi.com)
  • We report the case of an otherwise healthy 10-year-old girl with osteomyelitis of the left patella. (hindawi.com)
  • 13-15 Local recurrence is uncommon but can be seen in cases of inadequate surgical management or malignant transformation. (appliedradiology.com)
  • These findings suggest that chondroblastoma is derived from a mesenchymal cell undergoing chondrogenesis via active growth-plate signaling pathways (see Endochondral ossification). (wikipedia.org)
  • Joshi P, Lele V, Gandhi R . Fluorodeoxyglucose positron emission tomography-computed tomography scan and nuclear magnetic resonance findings in a case of Stewart-Treves syndrome. (bankersvascular.com)
  • Identification of worrisome signs and symptoms will also help in defining which cases may require further evaluation. (biomedcentral.com)
  • Skeletal disturbances such as localized warmth, pain, swelling and in some cases even pathologic fractures are the most common symptoms of ABC [9]. (symptoma.com)
  • Journal of Orthopaedic Case Reports is an International, Peer reviewed, online and which will be published every month (12 issues per year). (jocr.co.in)
  • Journal of Orthopaedic case reports is open access journal and all articles are available free immediately after publication. (jocr.co.in)
  • Chondroblastoma affects males more often than females at a ratio of 2:1 in most clinical reports. (wikipedia.org)
  • Journal of Clinical Case reports and Images welcomes distinctive sort of articles like case reports, case studies, lette. (oap-journals.info)
  • 2 ] A decade later, Jaffe and Lichtenstein renamed it as chondroblastoma and clearly separated it from giant cell tumor. (faoj.org)
  • [ 8 ] In 1956, Fairbank reported 14 cases and coined the term dysplasia epiphysealis hemimelica. (medscape.com)
  • DEH is a benign disorder, and no cases of malignant transformation have been reported. (medscape.com)
  • We present three case studies referred for evaluation to exclude retinoblastoma in which MFI assisted in making the diagnosis of PFV. (abstractarchives.com)
  • Less commonly, pathological fractures can be found, especially in cases involving the foot. (wikipedia.org)
  • Chondroblastoma in the foot most commonly occurs in subchondral areas of the talus and calcaneal apophysis. (faoj.org)
  • Sex hormones are thought to be linked to this process because of the spatial relationship of chondroblastoma with the growth plate and its typical occurrence before growth plate fusion. (wikipedia.org)