• The acyl carrier protein (ACP) is an important component in both fatty acid and polyketide biosynthesis with the growing chain bound during synthesis as a thiol ester at the distal thiol of a 4'-phophopantethiene moiety. (wikidoc.org)
  • ATA has the lowest specific activity in comparison with the other enzymes in the system and has been reported as catalyzing the rate-limiting step in the plant fatty acid synthetase (FAS) system: the thioester transfer reaction between acetyl-CoA and acyl carrier protein to form acetyl-ACP. (springer.com)
  • This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism. (uniprot.org)
  • In regards to future plans for the HGP-30 AIDS vaccine, Sarin said: "We plan to optimize conditions for linking HGP-30 to carrier proteins and to evaluate various adjuvants, so as to be able to obtain T-cell proliferative and CTL responses in all the immunized volunteers. (thefreedictionary.com)
  • This study examined the proportion of LMM biomarkers, which are bound to circulating carrier proteins. (hindawi.com)
  • Mass spectroscopic analysis of human serum following molecular mass fractionation, demonstrated that the majority of LMM biomarkers exist bound to carrier proteins. (hindawi.com)
  • Moreover, the pattern of LMM biomarkers bound specifically to albumin is distinct from those bound to non-albumin carriers. (hindawi.com)
  • Several insights emerged: a) Accumulation of LMM biomarkers on circulating carrier proteins greatly amplifies the total serum/plasma concentration of the measurable biomarker, b) The total serum/plasma biomarker concentration is largely determined by the carrier protein clearance rate, not the unbound biomarker clearance rate itself, and c) Examination of the LMM species bound to a specific carrier protein may contain important diagnostic information. (hindawi.com)
  • However, its signficantly better solubility provides greater flexibility in immunogen preparation protocols by allowing a broader range of buffer and pH conditions for coupling peptides, proteins and other haptens using classical crosslinkers such as glutaraldehyde, Sulfo-SMCC and EDC. (thermofisher.com)
  • Because of their large size and molecular complexity, KLH and CCH hemocyanins are carrier proteins of choice for use as immunogens to produce antibodies against haptens and peptides. (thermofisher.com)
  • Proteins 9, 10, 12, 22 and 54 are subunits of the TIM system that mediates import of multispanning carrier proteins into the inner membrane (IM). (gsf.de)
  • The CCH protein is composed of two very large polypeptide subunits (404/351 kDa) that form an extremely stable heterodidecameric structure even in the absence of divalent cations. (thermofisher.com)
  • Carrier Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • Interactions are determined by geometric criteria as described in K. Stierand, M. Rarey (2010), Drawing the PDB: Protein-ligand complexes in two dimensions, ACS Med. (rcsb.org)
  • Kahn's group of researchers found 'RBP4, a protein that transports vitamin A in the blood may be a cause for insulin resistance' from animal studies. (medindia.net)
  • A carrier precursor exiting the TOM channel is captured by the 70 kDa Tim9/10-complex in the intermembrane space and transferred to the 300 kDa inner membrane complex that contains Tim9p, Tim10p, Tim12p, Tim22p and Tim54p. (gsf.de)
  • Binding to the Tim22-complex triggers the membrane potential dependent insertion of mulitspanning carrier into the inner membrane. (gsf.de)
  • Inner membrane proteins 11, 17, 23 and 44 are members of, or closely adjacent to, the second TIM system ( Tim17-complex )that mediates transport of precursors carrying a targeting presequence. (gsf.de)
  • Because other vitamin carrier proteins (VCP) have been shown to be overexpressed in patients with malignant disease, we evaluated serum RCP levels in patients with adenocarcinoma of the breast. (aacrjournals.org)