Carotid body tumor. Medical search. Frequent questions

A carotid body tumor is also called a carotid body paraganglioma or a carotid body chemodectoma. (clevelandclinic.org)
We report on the preoperative embolization of a carotid-body paraganglioma by temporary balloon occlusion and ethanol injection. (nih.gov)
I was just diagnosed with paraganglioma and carotid body tumor. (mayoclinic.org)
The diagnosis of carotid body tumor, also known as a chemodectoma or paraganglioma, is typically made with radiological studies. (mayoclinic.org)
Objective: To report a case of a multiple paraganglioma with 5 concurrent locations and also describe a complication not found in the literature, spontaneous tumor bleeding. (scirp.org)
Köhler, H.F., Carvalho, A.L., Nishinari, K. and Kowalski, L.P. (2010) Internal Carotid Artery Reconstruction after Paraganglioma Resection: Report of Six Cases and Analysis of Available Techniques. (scirp.org)
On the basis of characteristic cytological features, a diagnosis of metastatic neuroendocrine tumor/paraganglioma was suggested. (cytojournal.com)
She underwent surgery, and resection of the tumor with neck dissection was performed, which was reported as malignant carotid body paraganglioma on histopathology. (cytojournal.com)
Ultimately, this caused a carotid body tumour, known as a paraganglioma. (amend.org.uk)
Parasympathetic PGLs are most often nonsecreting, although about 30% are associated with elevated levels of the dopamine metabolite 3-methoxytyramine (3-MT). [ 5 ] Pheochromocytoma (PHEO) and sympathetic paraganglioma (SPGL) are catecholamine-secreting tumors. (medscape.com)

Carotid body tumors (CBTs) are rare neoplasms, although they represent about 50-60% of head and neck paragangliomas. (medscape.com)
When choosing treatment, consider the following factors: the presence of other paragangliomas, the presence of bilateral carotid body tumors (CBTs), the age and the health of the patient, and the patient's preference. (medscape.com)
[ 9 ] Carotid body tumors (CBTs) constitute about 50-60% of head and neck paragangliomas. (medscape.com)
Compared with unembolized and polyvinyl-alcohol-embolized carotid-body paragangliomas, our technique resulted in no greater adverse effects on the tumor-vessel interface. (nih.gov)
Ask your doctor if he or she regularly treats people with this condition, as most doctors rarely (if ever) encounter paragangliomas and are unfamiliar with the best approaches to diagnosing and treating this rare tumor. (mayoclinic.org)
Under such conditions, it's important to seek a second opinion from a team that specializes in the care of people with rare neuroendocrine tumors such as paragangliomas. (mayoclinic.org)
Case report: A female patient of 32 years old complaining of tinnitus and diagnosed with five paragangliomas (jugulo-timpanic, bilateral carotid body and bilateral brachiocephalic trunk) through imaging studies. (scirp.org)
When such tumors arise outside of the adrenal gland, they are termed extra-adrenal pheochromocytomas, or paragangliomas. (medscape.com)
Of extra-adrenal tumors, known as paragangliomas, 30% are malignant. (msdmanuals.com)
Paragangliomas (PGLs) are rare neuroendocrine tumors that carry the highest degree of heritability among human neoplasms. (medscape.com)
Head and neck paragangliomas (HNPGLs) emerge from the parasympathetic nervous systemand are usually benign, slow-growing tumors. (medscape.com)

In the United States, the earliest successful carotid body tumor resection was performed by Scudder in 1903. (medscape.com)
Hayes Martin, in his textbook of head and neck tumors, recommended against resection of any tumor that is now considered a Shamblin type III (see Staging). (medscape.com)
A large retrospective, multicenter, international study analyzed the long-term outcome in 132 patients with primary radiation treatment or radiation after partial resection of a glomus tumor. (medscape.com)
Surgical resection of the tumor is the treatment of choice and usually cures the hypertension. (medscape.com)

Other significant medical history included palpitations, angina, and carotid endarterectomy. (medscape.com)

1 Common tumour sites include the carotid body in the head and neck and adrenal and extra-adrenal paraganglia in the abdomen. (bmj.com)

Computed tomography (CT) scanning of the head and neck is also helpful and typically reveals a hypervascular tumor located between the external and internal carotid arteries. (medscape.com)
Carotid body tumors are growths in the blood vessels near your carotid arteries. (clevelandclinic.org)
A carotid body tumor is a mass that grows in the blood vessels near the large arteries in either side of your neck (carotid arteries). (clevelandclinic.org)
The carotid body is a group of cells located at the bifurcation of the internal and external carotid arteries. (floridasurgicalclinic.com)
This requires a neck incision and possible excision of part of the carotid arteries. (floridasurgicalclinic.com)
On color Doppler evaluation, the lesion was observed to lie between the internal and external carotid arteries. (cytojournal.com)
Shamblin's classification is based on the relationship between tumor and carotid arteries, which has limitations. (pumch.cn)
Including both the horizontal relationship to carotid arteries and vertical extension of the tumors, PUMCH (Peking union medical college hospital) classification can better predict surgical complications and guide the surgery and thus might help to improve the surgical outcomes of the lesions. (pumch.cn)
The carotid arteries provide the main blood supply to your brain. (medlineplus.gov)

We propose the surgical technique detailed by the author as the method of choice for treatment of carotid body tumors in Iranian patients. (ac.ir)
Progress in imaging examination and surgical treatment of carotid body tumor[J]. Xueguan Yu Qiangnei Xueguan Waike Zazhi, 2020, 6: 439-441. (pumch.cn)

Some studies estimate that less than 10% of carotid body tumors are malignant (cancerous). (clevelandclinic.org)
Infrequently, these tumors run in families and can be malignant. (floridasurgicalclinic.com)
The average tumor size was 5.3 cm in diameter and was found to be malignant in four cases. (ac.ir)
Among the features that suggest a malignant course are large tumor size and an abnormal DNA ploidy pattern (aneuploidy, tetraploidy). (medscape.com)
In general, larger tumors are more likely to be malignant. (msdmanuals.com)
Overview of Multiple Endocrine Neoplasias (MEN) The multiple endocrine neoplasia (MEN) syndromes comprise 4 genetically distinct familial diseases involving adenomatous hyperplasia and malignant tumors in several endocrine glands. (msdmanuals.com)
Von Hippel-Lindau Disease (VHL) Von Hippel-Lindau disease is a rare hereditary neurocutaneous disorder characterized by benign and malignant tumors in multiple organs. (msdmanuals.com)
The tumor is malignant in 10% of cases but may be cured completely by surgical removal. (medscape.com)

[ 1 ] These tumors develop within the adventitia of the medial aspect of the carotid bifurcation. (medscape.com)
CECT revealed, in addition, a lobulated, ill-marginated enhancing space-occupying mass in the right carotid bifurcation. (cytojournal.com)
It was in close proximity to right common carotid artery beginning at the level of carotid bifurcation. (cytojournal.com)
A 3-D reconstruction optimized for vasculature (red) shows the location of the highly vascular mass (arrows) lying medial to the right mandibular salivary gland (MSG) at the level of the common carotid artery bifurcation (asterisk). (avma.org)
Carotid body tumor is a rare neoplasm located at the bifurcation of the carotid artery. (pumch.cn)

If the tumor is large, your vascular surgeon can embolize the tumor to shrink it prior to surgery. (floridasurgicalclinic.com)
Gulfcoast Ultrasound Institute is recognized as a worldwide leader in Vascular Ultrasound continuing medical education covering Carotid Ultrasound, Peripheral Vascular Sonography, and Transcranial Doppler Imaging. (gcus.com)
We used summary statistics from a genome-wide association study on each protein biomarker (meta-analysis of EpiHealth, PIVUS, ULSAM, and IMPROVE [Carotid Intima-Media Thickness and IMT-Progression as Predictors of Vascular Events in a High-Risk European Population]) and publicly available data from Global Lipids Genetics Consortium to perform Mendelian randomization analyses to address possible causality of protein levels. (lu.se)

Go to the Neuroendocrine Tumors (NETs) Support Group. (mayoclinic.org)
[ 10 ] SDH- associated syndromes are characterized by the development of PGLs, with an additional risk for developing other tumor types [ e.g. , clear cell renal cancer (RCC), gastrointestinal stromal tumors (GISTs), and, more rarely, neuroendocrine tumors and pituitary adenomas]. (medscape.com)

Various imaging studies can be used to confirm the diagnosis of carotid body tumor (CBT), starting with simple ultrasonography with color Doppler. (medscape.com)
Various imaging studies can be used to confirm the diagnosis of carotid body tumor (CBT), starting with simple ultrasonography with color Doppler, which can assess the vascularity of the neck mass and can sometimes reveal a possibility of a carotid body tumor (CBT), although it is not the best imaging modality to detect these tumors. (medscape.com)
Material and methods: All patients operated with a diagnosis of Carotid Body Tumor between 2005 and 2014 at the Obrero Hospital No. 1 of the National Health Fund in La Paz - Bolivia Results: 115 patients with an average age of 52 years (SD±11.725 and a mode of 57 years) were analyzed and operated on, of which 109 (94.80%) corresponded to the female gender with a ratio of 18: 1. (scienceopen.com)

The tumor was as equally frequent on the right as it was on the left, and was bilateral in four cases. (ac.ir)

Carotid body tumors are often painless, but your healthcare provider may want to remove the tumor because it can become large and affect the blood vessels in your neck or cause other symptoms. (clevelandclinic.org)
A carotid body tumor is suspected if a pulsatile mass in the neck is observed. (earsite.com)
Lateral projection image of whole-body FDG-PET shows the focal increased FDG activity in the lower mediastinum (blue arrow) and in the neck (red arrow). (medscape.com)

Are carotid body tumors benign? (clevelandclinic.org)
Most carotid body tumors are benign (not cancer ). (clevelandclinic.org)
However, most of the time these are benign, sporadic tumors. (floridasurgicalclinic.com)
Regardless of the histologic appearance, the tumor is considered benign if it has not invaded the capsule and no metastases are found, although exceptions occur. (msdmanuals.com)

Abstract Objective: To propose a preoperative classification of patients with Carotid Body Tumor and relate them to postoperative complications. (scienceopen.com)

Are there complications of carotid body tumor treatment? (clevelandclinic.org)
Many people who have treatment for a carotid body tumor don't have complications. (clevelandclinic.org)
Fine needle aspiration biopsy (FNAB) is seldom requested for this purpose due to rare but dreadful reported complications such as hemorrhage and damage to the carotid artery. (mayoclinic.org)

Being diagnosed with a pituitary tumor or pituitary disorder probably set many questions racing through your mind. (barrowneuro.org)
This experience means that our doctors and nurses have seen nearly every kind of pituitary tumor and disorder imaginable. (barrowneuro.org)
Not only is Barrow a place to receive the most advanced treatment and care for your pituitary tumor or disorder, we are also a place where you can help contribute to the scientific understanding and therapeutic research surrounding acromegaly, adenomas, gigantism, and other disorders that implicate the pituitary gland. (barrowneuro.org)

Healthcare providers often use surgery and embolization to treat carotid body tumors. (clevelandclinic.org)
Transcatheter embolization to stop blood flow to the tumor, which you may have before surgery to help shrink the tumor. (clevelandclinic.org)
This procedure is an effective and promising method of preoperative embolization of carotid-body tumors and warrants further experience and study. (nih.gov)
In this article, we also review the literature on carotid-body tumor embolization and ethanol embolization. (nih.gov)

A pheochromocytoma (see the image below) is a rare, catecholamine-secreting tumor derived from chromaffin cells. (medscape.com)
The term pheochromocytoma (in Greek, phios means dusky, chroma means color, and cytoma means tumor) refers to the color the tumor cells acquire when stained with chromium salts. (medscape.com)
Pritchett, J.W.: Familial Concurrence of Carotid Body Tumor and Pheochromocytoma. (tophipsurgeons.com)
A pheochromocytoma is a catecholamine-secreting tumor of chromaffin cells typically located in the adrenals. (msdmanuals.com)
A pheochromocytoma (see the image below) is a rare, catecholamine-secreting tumor that may precipitate life-threatening hypertension. (medscape.com)

The Enigma of Carotid and Aortic Body Tumors. (bvsalud.org)

Germline loss of function mutations followed by somatic loss of non-mutant alleles in the tumours 2- 4 suggests a tumour suppressor role for mitochondrial complex II in the paraganglia. (bmj.com)

In this report of 20 patients with 24 carotid body tumors which is the largest series reported so far from Iran, we have evaluated the various characteristics of this relatively rare tumor in our population and compared our results with that of the literature. (ac.ir)

The average tumor volume was 7.26 cm 3 . (medscape.com)

When providers surgically remove large carotid body tumors, a hole may remain in your carotid artery . (clevelandclinic.org)
The tumor can then be removed surgically. (floridasurgicalclinic.com)

The study found long-term successful control of the tumor growthi and mprovement of tinnitus and overall neurological status, as well as cranial nerve function. (medscape.com)

Several conditions can cause a facial paralysis e.g. stroke, brain tumor and Lyme disease. (krishnaherbals.com)
Brain tumor or other growth (mass). (medlineplus.gov)

Dall′Igna, C., Antunes, M.B. and Dall′Igna, D.P. (2005) Radiation Therapy for Glomus Tumors of the Temporal Bone. (scirp.org)

Carotid body tumors (CBTs) are treated with either surgery or radiotherapy. (medscape.com)
Descriptions of surgery for carotid body tumors have existed for over 100 years. (medscape.com)
Surgery to remove the tumor. (clevelandclinic.org)
Recovery time after surgery for a carotid body tumor is typically three to four weeks. (clevelandclinic.org)
If you have surgery to remove a carotid body tumor, you typically don't need further treatment. (clevelandclinic.org)
Surgery is the treatment of choice for glomus jugulare tumors. (medscape.com)
However, radiation therapy, particularly stereotactic radiosurgery (eg, Gamma Knife surgery), has been shown to provide good tumor growth control with a low risk of treatment-related cranial nerve injury. (medscape.com)
Of 22 patients with glomus jugulare tumors who underwent Gamma Knife surgery, neurologic status improved in 12 patients, 7 showed stable clinical condition, and 3 patients developed new moderate deficits. (medscape.com)

Familial pheochromocytomas and carotid body tumors may be due to mutations in genes encoding the enzyme succinate dehydrogenase or other signaling molecules. (msdmanuals.com)

Common locations for extra-adrenal pheochromocytomas include the organ of Zuckerkandl (close to the origin of the inferior mesenteric artery), bladder wall, heart, mediastinum, and carotid and glomus jugulare bodies. (medscape.com)

Often, glomus jugulare tumors are diagnosed within the sixth or seventh decade of life and can be followed by imaging only and may not need surgical intervention. (medscape.com)
Current surgical management of carotid body tumors[J]. J Vasc Surg, 2016, 64: 1703-1710. (pumch.cn)
A Systematic Review and Meta-Analysis of the Presentation and Surgical Management of Patients With Carotid Body Tumours[J]. Eur J Vasc Endovasc Surg, 2019, 57: 477-486. (pumch.cn)

The PUMCH Classification of Carotid Body Tumor[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(6): 825-828. (pumch.cn)

Vagal and Carotid Body Tumors. (scirp.org)

Paroxysmal attacks may be provoked by palpation of the tumor, postural changes, abdominal compression or massage, induction of anesthesia, emotional trauma, unopposed beta-blockade (which paradoxically increases blood pressure by blocking beta-mediated vasodilation), or micturition (if the tumor is in the bladder). (msdmanuals.com)

With regard to laboratory studies, check urinary catecholamines in patients who have any symptoms of a functional carotid body tumor (CBT). (medscape.com)
What are the symptoms of a carotid body tumor? (clevelandclinic.org)
A carotid body tumor may not cause any symptoms, but as the mass grows, it may press on nearby nerves and blood vessels. (clevelandclinic.org)
If your provider recommends observing the tumor (watchful waiting), let them know right away if you develop new symptoms. (clevelandclinic.org)
Therefore routine examination is not justifiable when symptoms relative to tumor presence are not present. (scirp.org)

Note that examining tumor tissue under a microscope cannot with certainty determine whether a tumor is cancerous. (mayoclinic.org)

Although pheochromocytomas have classically been associated with 3 syndromes-von Hippel-Lindau (VHL) syndrome, multiple endocrine neoplasia type 2 (MEN 2), and neurofibromatosis type 1 (NF1)-there are now 10 genes that have been identified as sites of mutations leading to these tumors. (medscape.com)

The sporadic form is the most common type, representing approximately 85% of carotid body tumors (CBTs). (medscape.com)

The carotid body, which originates in the neural crest, is important in the body's acute adaptation to fluctuating concentrations of oxygen, carbon dioxide, and pH. (medscape.com)

But carotid body tumor treatment can involve many blood vessels. (clevelandclinic.org)

Histologic evaluation revealed that the tumor contained diffuse ethanol-induced microemboli. (nih.gov)

Alpha-blockers and beta-blockers are useful for tumors secreting catecholamines. (medscape.com)

Anatomy4

Diseases8

Chemicals and Drugs1

Paraganglioma10

Paragangliomas11

Resection4

Endarterectomy1

Sites include the carotid body1

Arteries9

Treatment of carotid body2

Malignant8

Bifurcation5

Vascular3

Neuroendocrine2

Diagnosis3

Bilateral1

Neck3

Benign4

Postoperative complications1

Complications3

Pituitary Tumor3

Embolization4

Pheochromocytoma5

Aortic1

Paraganglia1

Rare tumor1

Average tumor1

Surgically2

Tinnitus1

Brain2

Temporal Bone1

Surgery8

Familial1

Adrenal1

Surgical3

Classification1

Vagal1

Abdominal1

Symptoms5

Cancerous1

Pheochromocytomas1

Sporadic1

Originates1

Blood vessels1

Histologic1

Catecholamines1