• Picornaviridae Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • This graph shows the total number of publications written about "Picornaviridae Infections" by people in this website by year, and whether "Picornaviridae Infections" was a major or minor topic of these publications. (childrensmercy.org)
  • Below are the most recent publications written about "Picornaviridae Infections" by people in Profiles. (childrensmercy.org)
  • We found that VCE-003 ameliorated the symptoms associated to TMEV infection, decreased microglia reactivity and modulated the expression of genes involved in MS pathophysiology. (nih.gov)
  • Theiler's murine encephalomyelitis virus (TMEV) is a single-stranded RNA murine cardiovirus from the family Picornaviridae. (wikipedia.org)
  • This is the proposed course of disease in TMEV infection in mice. (wikipedia.org)
  • The majority of mouse strains are not susceptible to the pathology associated with TMEV infection. (wikipedia.org)
  • Two weeks after TMEV infection, 42% of the untreated TMEV-infected mice were affected by marked inflammation with neuronal loss, whereas 58% exhibited minor inflammation without neuronal loss. (bvsalud.org)
  • Irrespective of the presence of neuronal loss, untreated mice lacked TMEV antigen expression within the hippocampus at 14 days post-infection (dpi). (bvsalud.org)
  • Thus, tamoxifen application during a TMEV infection is associated with transiently increased neuronal loss in the hippocampus, increased reactive astrogliosis and decreased neurogenesis in the DG. (bvsalud.org)
  • CONCLUSION: Our results suggest that after TMEV infection, the SVZ may mount an attempt at neuronal repair via emigration, a process dampened by decreases in neuroblast numbers. (ox.ac.uk)
  • TMEV is an enteric pathogen that primarily causes asymptomatic infections of the alimentary tract. (bibf1120.com)
  • However, extra-intestinal infection may appear and produce severe fatal encephalomyelitis or a chronic demyelinating ZM-447439 disease relevant for multiple sclerosis, with regards to the TMEV stress involved [3]. (bibf1120.com)
  • Nevertheless, this disease, that was isolated upon multiple passages in cell and mice ethnicities, displays close romantic relationship with TMEV and TRV, raising the chance that it represents a contaminating pet cardiovirus [5]. (bibf1120.com)
  • DECIDE brings together research teams from JMU, Würzburg University Hospital, and Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, from Helmholtz Centre for Infection Research in Braunschweig, Technical University of Berlin and University of Münster. (helmholtz-hiri.de)
  • The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection. (nupals.ac.jp)
  • Only recently, biochemical and structural studies made it possible to close the gaps in our knowledge on how cardiovirus 2A is able to act in diverse translation-related processes as a novel RNA-binding protein. (portlandpress.com)
  • Other picornaviruses, for example the cardioviruses, are believed to initiate replication at the endoplasmic reticulum and subvert PI4KIIIα to generate PI4P. (microbiologyresearch.org)
  • Saffold cardiovirus (SAFV) and characterize the pathogen, for the 5 untranslated region (UTR) ( 3 ). (cdc.gov)
  • After being cloned into the Saffold cardiovirus (SAFV) is a new piconavirus, origi- pGEM-T Easy vector (Promega, Madison, WI, USA), all nally identifi ed from fecal samples of a female infant PCR products were verifi ed by sequencing. (cdc.gov)
  • In 2007, the genomic series was reported of the cardiovirus, provisionally called Saffold disease (SAFV), amplified in cell tradition from the feces of a child showing with fever of unfamiliar source in 1981 [6]. (bibf1120.com)
  • An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. (lookformedical.com)
  • A genetically diverse and highly prevalent enteric viral infection, characteristics similar to the Enterovirus genus, was therefore identified substantially expanding the genetic diversity of the RNA viral flora commonly found in children. (ox.ac.uk)
  • APOBEC3B drives PKR-mediated translation shutdown and protects stress granules in response to viral infection. (uci.edu)
  • Genotoxic stress and viral infection induce transient expression of APOBEC3A and pro-inflammatory genes through two distinct pathways. (uci.edu)
  • Kilbride H, Jackson MA, Selvarangan R. Childhood Outcomes Following Parechovirus Infections in a US Young Infant Cohort. (childrensmercy.org)
  • Lymphocytic choriomeningitis virus (LCMV) carrier mice usually develop as a result of asymptomatic prenatal or neonatal infection, which induces tolerance to the virus. (freezingblue.com)
  • More frequently human infection resembles influenza or is asymptomatic. (freezingblue.com)
  • Therefore, the presence of low copy number of HBoV, detected by molecular method, may indicate prolonged viral shedding or an asymptomatic infection. (datexis.com)
  • The 5 and co-infections, we could not defi nitively say SAFV caused 3 UTR sequences were determined by using the RACE disease. (cdc.gov)
  • SAFV-3 infection occurs early in life ( 7 ), the pathogenicity tion test kit (SERODIA-MYCO II, Fujirebio, Japan). (cdc.gov)
  • Therefore, we figured SAFV-3 is a wide-spread and real human being disease leading to infection ZM-447439 early in existence. (bibf1120.com)
  • Cardiovirus is a genus of ssRNA+ viruses in the Picornaviridae family that infect vertebrates. (expasy.org)
  • The analysis of viral sequences verified that single infection of human adenovirus was the leading cause of gastroenteritis among infants and children, which was detected in 23.2% of the patients, followed by a mixed infection of human adenovirus and other viruses, which was detected in 20.9% of patients. (biomedcentral.com)
  • The clinical outcome of a virus infection may depend upon the conditions under which the infection is acquired: For example, poliomyelitis was seldom observed under conditions of poor sanitation, congenital rubella syndrome is a consequence of postponed childhood infection and some types of cancer are late events in which certain viruses play a crucial role. (bibf1120.com)
  • Among the 17 HBoV-positive patients who were also positive for infection with other viruses, 10 showed PIV infection. (datexis.com)
  • Previous studies have reported that HBoV infection was more prevalent among individuals who had other respiratory viruses [10, 22]. (datexis.com)
  • A unique feature of this approach: The CRC does not focus on a single pathogen, but combines research on several bacteria, viruses and fungi that frequently cause human infections. (helmholtz-hiri.de)
  • Our results showed that, in contrast to the enteroviruses and the cardioviruses, FMDV replication does not require PI4KIII (PI4KIIIα and PI4KIIIβ), and PI4P levels do not increase in FMDV-infected cells and PI4P is not seen at replication organelles. (microbiologyresearch.org)
  • This is, for example, the question of whether an active infection develops after contact with a pathogen or whether a localised infection turns into a systemic disease. (helmholtz-hiri.de)
  • We identified sequences distantly related to Seneca Valley virus and cardioviruses that were then used as genetic footholds to characterize multiple viral species within a previously unreported genus of the Picornaviridae family. (ox.ac.uk)
  • A Theiler's-like cardiovirus, called Vilyuisk human being encephalomyelitis disease (VHEV), continues to be implicated within an outbreak of the neurodegenerative disease among the Yakuts people in Vilyuisk, Siberia, in the 1950s. (bibf1120.com)
  • As for humans, EMCV infection seems to occur by the contact with animals and can cause febrile illnesses in some infected patients. (bvsalud.org)
  • Mice can transmit LCMV to __________, which can remain viremic and viruric for many months even if they contract infection as adults. (freezingblue.com)
  • Pick the terms that correctly complete this sentence: In adult mice with acute LCMV infection, virus multiplies in B cells/T cells and macrophages, whereas B cells/T cells are resistant. (freezingblue.com)
  • Pick the terms that correctly complete this sentence: Regarding LCMV infection in mice, internal viral epitopes induce humoral/cell-mediated responses, but surface epitopes elicit humoral/cell-mediated immunity and neutralizing antibodies. (freezingblue.com)
  • At the cellular level, what causes the lesions of LCMV infection in mice? (freezingblue.com)
  • Pick the term that correctly complete this sentence: Prenatal or neonatal LCMV infection in mice induces immunological tolerance/frank morbidity/death. (freezingblue.com)
  • What is considered a useful husbandry strategy for detecting LCMV infection in mice by seroconversion? (freezingblue.com)
  • Sendai viral replication during natural infection in mice is restricted to which system and which cell types. (freezingblue.com)
  • The interacademy conference, which features top international speakers and is organized with the support of the Alfried Krupp von Bohlen und Halbach Foundation and the Würzburg Helmholtz Institute for RNA-based Infection Research (HIRI), is scheduled to last until tomorrow, September 22. (helmholtz-hiri.de)
  • Würzburg, 25 November 2022-With the participation of the Helmholtz Institute for RNA-based Infection Research (HIRI), a new collaborative research center is being launched in Würzburg. (helmholtz-hiri.de)
  • In recent years, this profile establishment of HIRI and the Max Planck Research Groups for Systems Immunology on the Würzburg Medical Campus has further strengthened the infection research hub in Würzburg. (helmholtz-hiri.de)
  • Several studies have addressed HBV and HCV prevalence in migrants and ethnic minorities (9,10), but few studied viral hepatitis co-infections in HIV-infected persons according to the patients' geographic origins (11,12). (blogspot.com)
  • The high association of HBoV with PIV seems to be attributed to the high prevalence of PIV infection in 2006 (22.8% in May). (datexis.com)
  • Genes for tRNA recycling are upregulated in response to infections with Theiler's mouse encephalitis virus. (nupals.ac.jp)
  • Hematopoietic cell activation in the subventricular zone after Theiler's virus infection. (ox.ac.uk)
  • Within 12h of infection and before start of DNA replication, there begins early protein synthesis. (biologydiscussion.com)
  • Finally, the serosurvey proved that spread of EMCV is greater than the diffusion of fatal infections would suggest, due to subclinical circulation of EMCV. (bvsalud.org)
  • K. Shen) tients exhibited symptoms of respiratory tract infection, DOI: 10.3201/eid1607.091682 such as coughing, gasping, sneezing, or fever. (cdc.gov)
  • To investigate the epidemiological association of respiratory infection with viral load, HBoV-positive patients were categorized into low- and high-viral-load groups by using 1.0×106 copies/mL as a threshold value. (datexis.com)
  • These results suggest that single HBoV infection in the high-viral-load group may play an active role in respiratory infection. (datexis.com)
  • These findings are consistent with a Norwegian study that reported detection of HBoV alone and a high-viral-load were associated with respiratory tract infection. (datexis.com)
  • These findings also support the idea that a high-viral-load may be associated with a respiratory infection. (datexis.com)
  • Würzburg, September 21, 2023-On the occasion of the opening of the interacademy conference "MICROBIOLOGY 2023: from single cell to microbiome & host" , Jörg Hacker was welcomed as the guest of honor at the Institute for Molecular Infection Biology (IMIB) of the University of Würzburg (JMU) yesterday afternoon. (helmholtz-hiri.de)
  • Lesions of LCMV infection appear to develop from direct T cell-mediated damage to virus-infected cells and may involve humoral factors released from immune effector T cells. (freezingblue.com)
  • All principle investigators are leaders in infection biology and immunology. (helmholtz-hiri.de)
  • PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2. (nupals.ac.jp)
  • Infection initiates in astrocytes and microglia, but persists in macrophages. (wikipedia.org)
  • citation needed] One hypothesis for the initiation is that an infection stimulates the innate immune system, specifically perivascular microglia. (wikipedia.org)
  • The relevant question of whether authentic human cardioviruses exist has remained unclear for a long period. (bibf1120.com)
  • Lately, however, strong proof has been acquired for the lifestyle of human being cardioviruses. (bibf1120.com)
  • Human Brucella canis Infections Diagnosed by Blood. (blogspot.com)
  • It investigates critical decision processes that determine the outcome of human infection. (helmholtz-hiri.de)
  • Hacker, a bacteriologist, is considered a pioneer of molecular infection research and is also a co-founder of the interdisciplinary and cross-faculty Research Center for Infectious Diseases (ZINF) at JMU. (helmholtz-hiri.de)
  • To determine if hepatitis C virus seropositivity and active hepatitis B virus infection in HIV-positive patients vary with patients' geographic origins, we studied co-infections in HIV-seropositive adults. (blogspot.com)
  • Anti-Allergic, Antiviral And Antibacterial Properties-Harshingar Oil Can Be Used To Fight Bacteria Such As E.Coli, staph Infection and fungal Infection. (bajrangitraderandexporter.com)
  • Introduction Recent advancements in molecular recognition strategies (viral oligonucleotide microarrays and viral metagenomics techniques) have resulted in the identification of several new infections which are recognized not merely in symptomatic, but similarly in individuals without any clinical manifestation. (bibf1120.com)
  • So far hardly investigated on a broad scale, but of great importance here are certain key decisions that determine the clinical course of an infection. (helmholtz-hiri.de)
  • Despite the disease occurred endemically in pig farms since 1997, the recent increase of death experimented in Northern Italy prompted to furtherly investigate the evolution of the virus and the actual spread of the infection. (bvsalud.org)
  • Severe Parechovirus 3 Infections in Young Infants-Kansas and Missouri, 2014. (childrensmercy.org)
  • The question we addressed in our study was whether HCV seropositivity and active HBV infection in HIV-positive patients vary with the patients' geographic origins. (blogspot.com)
  • In this issue of Bioscience Reports (volume 42, issue 1), Caliskan and Hill provide a detailed view into the emerging roles of cardiovirus 2A protein, which is the primary factor for virulence during infections. (portlandpress.com)
  • gastrointestinal tract is the primary site of infection. (expasy.org)
  • First, a full-length functional ZIKV cDNA clone was engineered as a bacterial artificial chromosome, with each reporter gene under the cap-independent translational control of a cardiovirus-derived internal ribosome entry site inserted downstream of the single open reading frame of the viral genome. (mdpi.com)
  • ThV is the only cardiovirus to produce two additional proteins from an ORF overlapping the L protein, in another frame. (expasy.org)
  • Pérez Cachafeiro S, Caro-Murillo AM, Berenguer J, Segura F, Gutiérrez F, Vidal F. Association of patients' geographic origins with viral hepatitis co-infection patterns, Spain. (blogspot.com)
  • The lower detection rate and viral load of HBoV in older patients may be attributed to immunity acquired from an infection at a younger age. (datexis.com)
  • suggested that HBoV infection might develop only once because of the subsequent development of life-long immunity conferred by neutralizing antibodies produced in response to the infection. (datexis.com)