Cardiovascular safety. Medical search. Frequent questions

Despite a new meta-analysis claiming to show that testosterone replacement therapy for men with hypogonadism does not increase the risk of cardiovascular outcomes such as myocardial infarction or stroke, experts say the jury is still out. (medscape.com)
To address this uncertainty, Hudson and colleagues formed a global collaborative to obtain individual patient data on cardiovascular outcomes from randomized controlled trials of testosterone therapy for men with hypogonadism. (medscape.com)
The study was featured today at "The CAROLINA Trial-First Results of the Cardiovascular Outcomes Trial Comparing Linagliptin vs. Glimepiride" symposium. (biospace.com)
Conclusions Metformin is associated with beneficial cardiovascular outcomes in patients with diabetes only when (sub)clinical cardiovascular risk defined by NT-proBNP levels is present. (bmj.com)
Over the course of NIOSH's 50-year history, occupational chronic diseases, including cancer, cardiovascular disease, and adverse reproductive outcomes have always been a significant public health burden and source of economic costs. (cdc.gov)
The outcomes were upper limb sensorimotor function, health-related quality of life, level of independence, cardiovascular effects, and adverse events. (karger.com)
Objective Longitudinal clinical registry-infrastructures such as Anti-Rheumatic Therapies in Sweden (ARTIS) allow simultaneous comparison of the safety of individual immunomodulatory drugs used in clinical practice, with consistent definitions of treatment cohorts, follow-up and outcomes. (lu.se)
Our objective was to assess and compare incidence rates of key safety outcomes for individual targeted synthetic or biological disease-modifying antirheumatic drugs (b/ts DMARDs) in rheumatoid arthritis (RA), updating previous reports and including newer treatments including Janus Kinase inhibitors (JAKi). (lu.se)
The agreement includes an endowment from Sleep Number to Mayo Clinic to further sleep science research with an emphasis on cardiovascular medicine, and a dedicated research and development fund that will improve health care quality and clinical outcomes with potential life-changing benefits. (ksl.com)
A large study, enrolling over 20,000 patients, is looking at the occurrence of cardiovascular adverse outcomes. (medscape.com)
This study certainly should provide us with interesting information about cardiovascular outcomes of selective COX-2 inhibitor therapy. (medscape.com)

In contrast, the European Medicines Agency concluded that when hypogonadism is properly diagnosed and managed, there is currently no clear, consistent evidence that testosterone therapy causes increased cardiovascular risk . (medscape.com)
Objectives/Background Based on previous experiences, the Food and Drug Administration and the European Medicines Agency recommend that clinical trials for novel antidiabetic drugs are powered to detect increased cardiovascular risk. (bmj.com)
Using real-world data (RWD) from three U.S. claims data sets, we aim to predict the findings of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type 2 Diabetes (CAROLINA) comparing linagliptin versus glimepiride in patients with type 2 diabetes (T2D) at increased cardiovascular risk by using a novel framework that requires passing prespecified validity checks before analyzing the primary outcome. (diabetesjournals.org)
Within Medicare and two commercial claims data sets (May 2011-September 2015), we identified a 1:1 propensity score-matched (PSM) cohort of T2D patients 40-85 years old at increased cardiovascular risk who initiated linagliptin or glimepiride by adapting eligibility criteria from CAROLINA. (diabetesjournals.org)

His experience in cardiovascular imaging stretches over the last 25 years and has included directing a prominent atherosclerosis imaging core laboratory which supported research in dyslipidemia, coronary intervention, intravascular ultrasound, cardiac transplantation, valve disease, hypertension and AAA, devices to name a few. (xtalks.com)
Cardiac monitoring during tooth extraction was performed in 7077 elderly patients with hypertension and other chronic diseases, and the influence of various factors on safety of tooth extraction was evaluated. (medscimonit.com)
Additionally, 89 patients with primary hypertension were recruited, and electrocardiogram was monitored with a general monitor or a Holter monitor, and the detection rate of cardiovascular events was compared between the 2 groups. (medscimonit.com)
In the cardiovascular system, mercury induces hypertension in humans and animals that has wide-ranging consequences, including alterations in endothelial function. (hindawi.com)
Additionally, work-related risk factors for cardiovascular disease may also increase the risk of other cardiovascular disease risk factors such as hypertension, diabetes, obesity, unhealthy diet, leisure-time physical inactivity, and excessive alcohol use. (wikipedia.org)
In fact, death rates from all causes have been increasing since about 2012 in working-age people (25-64 years), primarily due to increases in drug (mainly opioid) overdoses, alcohol abuse, suicides, and chronic diseases, such as cardiovascular diseases, hypertension and diabetes. (wikipedia.org)
data to study the association between cardiovascular fitness and other health conditions and risk factors, such as obesity, cardiovascular disease, diabetes, hypertension, and activity and dietary patterns. (cdc.gov)
Obese firefighters are at risk for hypertension and cardiovascular disease associated with frequent fatal cardiac events. (cdc.gov)
Platelets have a "key role" in atherogenesis and its thrombotic complications in subjects with DM [ 3 ], and the concomitant presence of multiple "classical" cardiovascular risk factors (arterial hypertension, cigarette smoking, and hyperlipidemia) in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)

CVD is a major risk for and the leading cause of death for people living with T2D, and since 2008, the FDA requires diabetes medications to demonstrate cardiovascular (CV) safety. (biospace.com)
The commentary on the trial by Marso et al 1 assessing the cardiovascular (CV) safety of a new agent for treating type 2 diabetes highlights a recognised dilemma in clinical research on CV risk in assessment of new therapeutic agents. (bmj.com)
Related explanations for cardiovascular disease trends are increases in the prevalence of other stress-related (including work-related stress) conditions, obesity, diabetes, metabolic syndrome, and short sleeping hours. (wikipedia.org)
TITUSVILLE, NJ, October 30, 2018 - The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved INVOKANA ® (canagliflozin) to reduce the risk of major adverse cardiovascular (CV) events, including heart attack, stroke or death due to a cardiovascular cause in adults with type 2 diabetes (T2D) who have established CV disease. (jnj.com)
Not only does INVOKANA ® enable patients to control their diabetes symptoms by lowering their A1C levels, but it now also helps protect them from potentially devastating cardiovascular events. (jnj.com)
Janssen's oral diabetes treatment is now the first and only oral diabetes treatment to have an indication to reduce the risk of heart attack, stroke or cardiovascular death. (jnj.com)
Janssen's oral #diabetes treatment now approved to reduce the risk of major cardiovascular (CV) events in adults with #T2D who have established CV disease. (jnj.com)
Large clinical trials have shown that antiplatelet agents are effective in the prevention of recurrent cardiovascular events in diabetes. (hindawi.com)
The scientific statement focused on the CKM construct, specifically highlighting CKM syndrome, which is a newly described multisystem syndrome that involves the interactions of risk factors-such as obesity, type 2 diabetes and other metabolic abnormalities, CKD, and cardiovascular disease risk-associated with poor health, organ damage, cardiovascular events, and early death. (pharmacytimes.com)
For patients at stage 4, Ndumele explained that these individuals have progressed all the way to clinical cardiovascular disease, overlapping with the preceding metabolic risk factors, such as obesity, diabetes, high blood pressure, or CKD. (pharmacytimes.com)

We therefore evaluated association of metformin and sulfonylureas with cardiovascular events in patients with different cardiovascular risk profiles indicated by N-terminal of the prohormone brain natriuretic peptide (NT-proBNP) levels. (bmj.com)
This study aimed to evaluate the safety of tooth extraction in elderly patients with cardiovascular diseases. (medscimonit.com)
The Holter monitor is superior to the general monitor in identifying cardiovascular events in high-risk elderly patients undergoing tooth extraction, and can be used in this population. (medscimonit.com)
in fact, ∼64% of people suffering from COPD are treated for a concomitant cardiovascular disease and approximately one in three COPD patients die as a consequence of cardiovascular diseases. (ersjournals.com)
The TAVR UNLOAD trial is an international, multi-center, randomized, open-label, clinical trial comparing the safety and efficacy of Transcatheter Aortic Valve Replacement (TAVR) with the SAPIEN 3 Valve and optimized heart failure therapy ( OHFT ) versus OHFT in heart failure (HF) patients, with moderate aortic stenosis ( AS). (tuftsmedicalcenter.org)
Collecting and storing heart tissue and blood samples from consented Tufts Medical Center patients for the purpose of cardiovascular research. (tuftsmedicalcenter.org)
In addition to alterations in atherosclerotic markers, abnormalities in cardiac function and structure have been reported among patients with GHD possibly contributing to the increased cardiovascular mortality. (knowcancer.com)
This session explores the links between nutritional-metabolic parameters and cardiovascular pathology in dialysis patients, describing fundamental mechanisms and the implications for treatment. (asn-online.org)
Comparative cardiovascular safety of LABA/LAMA FDC versus LABA/ICS FDC in patients with chronic obstructive pulmonary disease: a population-based cohort study with a target trial emulation framework. (bvsalud.org)
Our findings provide important reassurance about comparative cardiovascular safety of LABA/LAMA FDC treatment among patients with COPD . (bvsalud.org)
Lung cancer patients with higher amounts of coronary artery calcium have an increased risk of an adverse cardiovascular event as a result of thoracic radiation therapy compared to patients with no coronary artery calcium. (medicalxpress.com)
Recognizing patients with a high burden of coronary artery calcium allows for the implementation of risk modification therapies to reduce cardiovascular risk, such as aspirin and statin therapy. (medicalxpress.com)
It is an important step forward for patients and the physicians who treat them," said James List, M.D., Ph.D., Global Therapeutic Area Head, Cardiovascular & Metabolism, Janssen Research & Development, LLC. (jnj.com)
For patients with T2D and clinical CV disease, the ADA recommends medication management with SGLT2 (sodium-glucose cotransporter-2) inhibitors that specifically have a proven cardiovascular benefit. (jnj.com)
Although, currently, treatment has proven useful in reducing vascular events, diabetic patients continue to have a higher risk of adverse cardiovascular events compared with those in nondiabetic patients. (hindawi.com)
Cardiovascular (CV) diseases are the leading cause of morbidity and mortality in diabetic patients. (hindawi.com)
Methods Patients were selected from the Japan Cardiovascular Surgery Database, which includes almost all cardiovascular surgeries in Japan, if they underwent isolated coronary artery bypass graft (CABG), valve or thoracic aortic surgery from 2013 to 2016. (bmj.com)
The study consisted of 4,362 patients who had at least one cardiovascular risk factor. (hollislawfirm.com)
Notably, the greatest burden of CKM syndrome on patients is its cardiovascular effects, which are associated with the greatest clinical impact. (pharmacytimes.com)
[ 1 ] This study was an efficacy and safety study looking at tocilizumab in patients with documented giant cell arteritis to see whether tocilizumab improved the remission of patients after tapering from glucocorticoid therapy. (medscape.com)
There is another comparative cardiovascular safety study that was conducted looking at etanercept compared with tocilizumab in patients with rheumatoid arthritis (RA). (medscape.com)
Lipid-lowering therapy is important for secondary prevention for patients with known cardiovascular disease, as well as for primary prevention for those at increased risk. (medscape.com)
As suboptimal control keeps them at continued cardiovascular risk, such patients should be thoroughly evaluated for true statin intolerance , and adjunctive or alternative therapies should be considered. (medscape.com)

Cardiovascular mortality in growth hormone (GH) deficient adults has been shown to be increased in a number of retrospective studies. (knowcancer.com)
In addition, GHD is associated with cardiac autonomic dysfunction that may also contribute to cardiovascular mortality and improves with GH replacement therapy. (knowcancer.com)
Cardiovascular disease is the leading cause of mortality in women. (knowcancer.com)
Between 2000-2015, the cardiovascular disease mortality gap between the U.S. and other wealthy countries has widened. (wikipedia.org)
The reason we care about [CKM syndrome] is because it's associated with significantly premature mortality, and most of that mortality is due to cardiovascular disease," Ndumele said during the session. (pharmacytimes.com)
Mortality, major adverse cardiovascular events (MACEs), target vessel failure, and stent thrombosis (ST) occur more frequently as the result of calcium-mediated poor lesion preparation, stent under expansion, and stent malapposition ( 2 ). (frontiersin.org)

The researchers then assessed the incidence of major adverse cardiovascular events, such as heart attack or stroke, after initiation of radiation therapy across the coronary artery calcium groups. (medicalxpress.com)
There were three major adverse cardiovascular events in the no coronary artery calcium group, seven events in the mild group, five in the moderate group and five in the severe group. (medicalxpress.com)
After adjusting for age and sex, coronary artery calcium group was associated with increased risk of major adverse cardiovascular events. (medicalxpress.com)
Effectiveness (angiographic success) and safety [major adverse cardiovascular events (MACEs) and IVL-related procedural complications] endpoints were assessed. (frontiersin.org)

0828-282X/Ó 2021 Canadian Cardiovascular Society. (bvsalud.org)
The new Decade of Action for Road Safety 2021-2030 has the ambitious target of preventing at least 50% of road traffic deaths and injuries by 2030. (who.int)
In a statement released on February 4, 2021 , the U.S. Food and Drug Administration (FDA) informed the public that initial results from a safety clinical trial of the medication Xeljanz, Xeljanz XR (tofacitinib) may be cause for concern. (hollislawfirm.com)

Nissen, a cardiologist at Cleveland Clinic, Ohio, added that the individual trials were heterogeneous, with "very few real cardiovascular events," so the meta-analysis "is not definitive," he said in an interview. (medscape.com)
Certainly, great caution is advised regarding the use of testosterone replacement therapy in people with established atherosclerosis due to the findings of plaque progression in the testosterone trials and the excess cardiovascular events observed in the TOM trial, write Michos and fellow editorialist Matthew J. Budoff, MD, of UCLA, in their editorial. (medscape.com)
A cardiovascular seminar about strengthening the community response to cardiac arrest events is taking place Nov. 18 from 2 to 3:15 p.m. (ohsonline.com)
The primary endpoint was defined as a combination of cardiovascular events and death. (bmj.com)
Detection rate of cardiovascular events by use of a Holter monitor was significantly higher than with a general monitor. (medscimonit.com)
Inhaled bronchodilators might have adverse cardiovascular effects, including ischaemic events and arrhythmias, and beta-blockers might adversely influence the respiratory symptoms and the response to bronchodilators. (ersjournals.com)
Because inhaled bronchodilators cause adverse cardiovascular effects, including ischaemic events and arrhythmias, and beta-blockers could adversely influence respiratory symptoms and the response to bronchodilators, it is important to know the safety profiles and the possible interactions between these two classes of drug, in order to use them with greater awareness. (ersjournals.com)
The outcome of interest was a hospitalized composite cardiovascular events of acute myocardial infarction , unstable angina , heart failure , cardiac dysrhythmia , and ischemic stroke . (bvsalud.org)
Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for composite and individual cardiovascular events after matching up to five LABA/LAMA FDC initiators to one LABA/ICS FDC initiator using propensity scores (PS). (bvsalud.org)
serious adverse events ( Likely Cardiovascular Serious Adverse Events: Placebo-Controlled Group ). (lillymedical.co.uk)
Antiplatelet agents are effective in primary and secondary prevention of arterial thrombosis (cardiovascular events, ischaemic stroke, and peripheral arterial occlusive disease). (hindawi.com)
In the post-marketing study, the safety of tofacitinib was tested in comparison to a tumor necrosis factor (TNF) inhibitor with respect to adverse effects and malignancies, including serious cardiovascular events and cancers. (hollislawfirm.com)
Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. (nih.gov)

Though sulfonylureas are one of the widely prescribed drugs both in developed and developing countries and have proven their efficacy for glycemic control and prevention of microvascular complications, there is considerable uncertainty about its cardiovascular safety which has been going on for nearly five decades. (eurekaselect.com)
In this review, we will critically analyze the efficacy and cardiovascular safety of sulphonylureas, based on the latest available literature to clarify their role in our day-to-day clinical practice. (eurekaselect.com)
Eagles Eye View: What is the Safety and Efficacy of Redo-TAVR? (acc.org)
This review aimed to evaluate the efficacy and safety of VNS as a novel treatment option for post-stroke recovery. (karger.com)
RCTs investigating the efficacy or safety of VNS on post-stroke recovery were included. (karger.com)

P = .62), nor were there any significantly increased risks of death, stroke, or different types of cardiovascular outcome, although those numbers were small. (medscape.com)
The health-enhancing effects of cycling may help improve cholesterol levels , which can boost your cardiovascular health and lower your chances of stroke and heart attack. (healthline.com)

This Funding Opportunity Announcement (FOA) invites applications for clinical or community sites to be part of a multi-center group- or cluster-randomized trial under the Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) program. (nih.gov)
ENRICH will aim to test the effectiveness of an implementation-ready intervention designed to promote cardiovascular health (CVH) and address CVH disparities in both mothers and children (0-5 years old) who are of low socio-economic status (SES), live in low-resource rural or urban communities, or who are in diverse geographic regions of the U.S. with high burden of cardiovascular disease (CVD) risk factors. (nih.gov)

Headquartered at McLaren Macomb, the new cardiovascular program includes eight employed cardiologists who practice at McLaren Macomb in Mount Clemens and McLaren Oakland in Pontiac. (crainsdetroit.com)
The Cardiovascular Imaging Center has a large staff of seven radiologists, fifteen cardiologists, and 5 pediatric cardiologists who are dedicated to cardiovascular imaging, and encompassing a broad range of expertise. (clevelandclinic.org)

This fellowship is designed to train cardiovascular radiology specialists in advanced Cardiovascular Magnetic Resonance, and Cardiovascular Computed Tomography. (clevelandclinic.org)
The one year program is designed to offer training and expertise in cardiovascular magnetic resonance and computed tomography and to begin research in cardiovascular imaging. (clevelandclinic.org)

In this article, we review the literature about the epidemiology of COPD, its association with cardiovascular diseases, and the safety of concurrent use of inhaled bronchodilators and beta-blockers, as a tool for improving the approach to complex therapies in clinical practice. (ersjournals.com)
Research on its health benefits took off in the 1970s and 80s, with particular interest in its association with cardiovascular disease sharpening in the 1990s. (foodinsight.org)

The present cohort study aimed to examine comparative cardiovascular safety of LABA/LAMA and LABA/ICS with a target trial emulation framework, focusing on dual fixed- dose combination (FDC) therapies . (bvsalud.org)

Primordial prevention focuses on population-based healthy lifestyle choices to minimize coronary risk factors, whereas primary prevention seeks to delay or prevent the onset of cardiovascular disease. (medscape.com)
A recent webinar from the National Occupational Research Agenda's Cancer, Reproductive, Cardiovascular, and Other Chronic Disease Prevention (CRC) cross-sector council describes research related to the potential effects of occupational physical activity on workers' cardiovascular health. (cdc.gov)
Primary prevention of cardiovascular diseases, including workplace health promotion, is key to reducing death rates. (wikipedia.org)
7 Cicarrone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, USA. (nih.gov)
14 Cardiovascular Prevention Unit, Adult Cardiology Department. (nih.gov)

Cardiovascular diseases are the leading cause of death worldwide except Africa. (wikipedia.org)

The present study sought to determine the incidence of COVID-19 vaccine cardiovascular complications in Team USA athletes. (nih.gov)
It was predicted that there would be a low incidence of cardiovascular complications from COVID-19 vaccination in Team USA athletes. (nih.gov)
Supposedly, this is the first study to investigate the incidence of COVID-19 vaccine cardiovascular complications in elite athletes. (nih.gov)

Objective: Firefighter obesity can adversely affect personal health and public safety, as well as contribute to increased costs directly, by treatment of comorbid conditions, or indirectly by loss of productivity. (cdc.gov)

Cardiovascular disease (CVD) risk factors associated with lifestyle include smoking, alcohol intake, diet, and exercise. (medscape.com)
The growth hormone deficiency (GHD) syndrome is associated with a cluster of cardiovascular-risk factors such as central adiposity, increased visceral fat, insulin resistance, dyslipoproteinemia and decreased plasma fibrinolytic activity. (knowcancer.com)
The vast majority of studies have focused primarily on men and the gender-specific effects of GH replacement on cardiovascular risk factors remain unknown. (knowcancer.com)
Effects of GH replacement on bone density may be less pronounced in women and because specific GH effects on cardiovascular risk factors in women are unknown, many adult women with GHD are untreated. (knowcancer.com)
The CANVAS (CANagliflozin cardioVascular Assessment Study) Program evaluated the effect of INVOKANA ® on CV risk in a broad population of more than 10,000 adults with T2D who had established CV disease (65 percent) or were at risk for cardiovascular disease with two or more risk factors (35 percent). (jnj.com)
Moreover, the concomitant presence of multiple "classical" cardiovascular risk factors in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)
There is no pinpointing the exact cause of cardiovascular disease, but there are risk factors that can increase the chances of having cardiovascular disease. (saintfrancishosp.com)

Many new classes of drugs that are currently available including DPP-4 inhibitors, GLP-1 agonists and SGLT-2 inhibitors have undergone cardiovascular outcome trials which had been made mandatory by the regulatory authority and thereby established their cardiovascular safety or at least neutrality. (eurekaselect.com)
This is clearly a very important study because the potential for selective cyclo-oxygenase 2 (COX-2) inhibitors to increase cardiovascular risk is significant. (medscape.com)

We registered the protocol ( NCT03648424 , ClinicalTrials.gov) before evaluating the composite cardiovascular outcome based on CAROLINA's primary end point. (diabetesjournals.org)
Linagliptin was associated with a 9% decreased risk in the composite cardiovascular outcome with a CI including the null (HR 0.91 [0.79-1.05]), in line with noninferiority. (diabetesjournals.org)
In a nonrandomized RWD study, we found that linagliptin has noninferior risk of a composite cardiovascular outcome compared with glimepiride. (diabetesjournals.org)

Further, additional cardiovascular MRI and CT scans are acquired from multiple MRI and CT scanners across the regional Cleveland Clinic network of hospitals and imaging centers. (clevelandclinic.org)

Before starting a cardiovascular exercise program you should consult with your physician, especially if you suffer from a chronic health condition. (personalhealthzone.com)
Detailed descriptions of the protocol are provided in the NHANES Cardiovascular Fitness Procedure Manual (National Center for Health Statistics, 2004). (cdc.gov)
Heart rate variability (HRV), the beat-to-beat change in heart rate, can tell you a lot about your cardiovascular health. (holisticprimarycare.net)
Health Impacts Safety: Safety Meeting Guide. (cdc.gov)
Afghanistan has addressed road safety by integrating its approach with other issues on the national health agenda. (who.int)
As one of the most researched foods in nutrition science, studies on soy are regularly published on topics ranging from its effects on cardiovascular health to how it impacts our gut microbiome. (foodinsight.org)
Studies on soy and cardiovascular disease continued, and many showed more moderate effects than those used as evidence to support the FDA health claim. (foodinsight.org)
In 2006 the American Heart Association (AHA) published a paper concluding that, "many soy products should be beneficial to cardiovascular and overall health because of their high content of polyunsaturated fats, fiber, vitamins, and minerals and low content of saturated fat", while at the same time questioning the strength of the evidence supporting a strong link between soy and decreased low-density lipoprotein (LDL) cholesterol. (foodinsight.org)
Ludwig Boltzmann Institute for Digital Health and Patient Safety, Medical University of Vienna, Vienna, Austria. (nih.gov)
This novel and important investigative opportunity will provide a robust foundation upon which to further our understanding of sleep and sleep disorders, and their interactions with health and disease," said Dr. Somers, the Alice Sheets Marriott Professor of Medicine, and Physician in Cardiovascular Medicine at Mayo Clinic. (ksl.com)
That's what we want to preserve-individuals with ideal cardiovascular health. (pharmacytimes.com)
In this chapter, you will discover diseases that affect the cardiovascular system, the treatment of these diseases, and the effects on the client's general health status. (informit.com)

However, there is a paucity of literature regarding the safety of using titanium wires compared to that on the safety of steel wires for sternum closure after cardiac surgery. (thieme-connect.de)
While not establishing causal relationships, the findings raise concerns regarding vaccine-induced undetected severe cardiovascular side-effects and underscore the already established causal relationship between vaccines and myocarditis, a frequent cause of unexpected cardiac arrest in young individuals. (nature.com)

We believe further study evaluating the utility of coronary artery calcium burden in determining cardiovascular risk in other cancer populations is warranted and can help validate coronary artery calcium burden across different populations. (medicalxpress.com)
The preliminary results from the safety study indicate an increased risk of cancer and cardiovascular risk in relation to the arthritis medication. (hollislawfirm.com)

The most common cause of cardiovascular disease is narrowing or blockage of the coronary arteries, the blood vessels that supply blood to the heart itself. (tuftsmedicalcenter.org)
Cardiovascular disease ( CVD ) is any disease involving the heart or blood vessels . (wikipedia.org)
There are many cardiovascular diseases involving the blood vessels. (wikipedia.org)
Occupational cardiovascular diseases (CVD) are diseases of the heart or blood vessels caused by working conditions, making them a form of occupational illness. (wikipedia.org)
Cardiovascular diseases are a group of conditions that affect the heart and blood vessels. (saintfrancishosp.com)
The cardiovascular system is comprised of the heart and blood vessels and is responsible for the transport of oxygen and nutrients to organ systems of the body. (informit.com)

A recent study showed that dietary changes can have as profound an effect on cardiovascular risk as statin drug therapy. (holisticprimarycare.net)

In 2014, the US Food and Drug Administration (FDA) mandated a label on testosterone products warning of possible increased cardiovascular risks and to reserve the therapy for symptomatic hypogonadism only. (medscape.com)
Little is known about the cardiovascular risks for miners in the US as most research to date has focused on respiratory illness. (cdc.gov)
Conclusion Data from ARTIS supports that the b/tsDMARDs currently used to treat RA have acceptable and largely similar safety profiles, but differences exist in particular concerning tolerability and specific infection risks. (lu.se)

Hormone (GH) replacement in women with GH deficiency on the basis of pituitary/hypothalamic region tumors, radiation, or surgery on cardiovascular risk markers and arterial distensibility. (knowcancer.com)
Each atherosclerotic lesion represents a different stage of a chronic inflammatory process in the arterial wall and different markers along the inflammatory cascade have been reported to predict cardiovascular risk [34]. (knowcancer.com)

There were no significant differences in the cardiovascular (CV) safety profiles of galcanezumab and placebo in the study populations. (lillymedical.co.uk)

There are many therapies that have been shown to have adverse cardiovascular implications and fortunately, innovative tests and tools are available that are effective in monitoring the safety of new biologics, drugs and devices in development. (xtalks.com)
The goal of this webinar is to discuss the application of cardiovascular imaging when monitoring safety in the development of new medical therapies. (xtalks.com)
What do you know about the safety and tolerability of lipid-lowering therapies? (medscape.com)

Despite reassuring scientific data, the lay press and social media continue to propagate largely unsubstantiated claims that a significant number of athletes have died from cardiovascular complications related to COVID-19 vaccines. (nih.gov)

When compared to no coronary artery calcium, the mild group was associated with 11.7 times increased risk for a major adverse cardiovascular event and severe coronary artery calcium had a 21.4 times increased risk. (medicalxpress.com)

The Section of Cardiovascular Imaging is physically located within the Miller Pavilion, home to the Heart, Vascular & Thoracic Institute, giving the fellow the opportunity to also serve as an integral member of a multi-disciplinary clinical team. (clevelandclinic.org)

In CAROLINA, we wanted to test this question using a current-generation sulfonylurea, and we found that glimepiride does not increase cardiovascular risk relative to linagliptin. (biospace.com)

Hear from L. Leonardo Rodriguez, MD, a staff cardiologist in the Section of Cardiovascular Imaging. (clevelandclinic.org)

Together with Steven Nissen, MD, an investigator for the TRAVERSE trial, she agrees that this new evidence is not yet decisive, largely because the individual trials in the meta-analysis were short and not designed as cardiovascular outcome trials. (medscape.com)

He completed his training in both Internal Medicine and Cardiovascular Diseases at the National Naval Medical Center in Bethesda, Maryland. (xtalks.com)
In addition, recognizing cardiovascular risk allows the care team to make a better assessment of the patient's overall prognosis, which can guide therapy choice and goals of care discussions," said Matthew Lui, MD, an internal medicine resident at Washington University in St. Louis and the study's lead author. (medicalxpress.com)

We should continue to use caution as indicated by the FDA label and only use testosterone therapy selectively in people who have true symptoms of hypogonadism," and be cautious about using it particularly in men at higher cardiovascular risk due to family history or known personal heart disease. (medscape.com)
The American Heart Association's most important U.S. cardiovascular annual meeting, the Scientific Sessions , are under way at the Dallas Convention Center through Nov. 20. (ohsonline.com)
There are many different forms of cardiovascular (heart) disease. (tuftsmedicalcenter.org)
Two hospitals affiliated with Flint-based McLaren Healthcare Corp. have launched the McLaren Cardiovascular Institute to expand heart services in Southeast Michigan at McLaren Macomb and McLaren Oakland hospitals. (crainsdetroit.com)
In addition to these services, expanded cardiovascular capabilities will include innovative techniques and procedures to treat chronic total occlusion, pulmonary embolisms and deep vein thrombosis, chronic heart failure and other forms of heart disease. (crainsdetroit.com)
There are also many cardiovascular diseases that involve the heart. (wikipedia.org)
There is active research in all areas of cardiovascular imaging, including ventricular mechanics, ischemic heart disease, hypertrophic cardiomyopathy, congenital heart disease, and valvular disease. (clevelandclinic.org)
Average and max radiation dose to the heart were not associated with a major adverse cardiovascular event in the researchers' time to event analysis. (medicalxpress.com)
Usually associated with a build-up of fat in the arteries and increased risk of blood clots, cardiovascular diseases are associated with damage to arteries in the brain, heart, kidneys and eyes. (saintfrancishosp.com)
The American Heart Association published a statement describing the cardiovascular-kidney-metabolic (CKM) construct, specifically highlighting treatment challenges for CKM syndrome. (pharmacytimes.com)

Cardiovascular disease (CVD) is responsible for 1 out of every 3 deaths in the United States, making it the leading cause of death. (cdc.gov)
In the United States, cardiovascular diseases account for one out of four deaths. (wikipedia.org)
The 6th International Conference on Work Environment and Cardiovascular Diseases found that within the working age population about 10-20% of cardiovascular disease deaths can be attributed to work. (wikipedia.org)

[3] Most cardiovascular disease affects older adults. (wikipedia.org)

This is "the most comprehensive study to date investigating the safety of testosterone treatment of hypogonadism," according to the researchers. (medscape.com)
The study is being presented at the American College of Cardiology's Advancing the Cardiovascular Care of the Oncology Patient virtual course on Feb. 11-12, 2022. (medicalxpress.com)
The next study that I would like to allude to is the PRECISION trial, which is a cardiovascular study that is comparing celecoxib vs naproxen therapy. (medscape.com)

Prior to joining Bioclinica, Tim supported a renowned academic research group at the Cleveland Clinic, leading their new business activities with a focus on the cardiovascular imaging sector of clinical trials. (xtalks.com)
Mr. Horvath has been with Bioclinica for over 18 years, making significant contributions to imaging protocol design and review methodology for clinical trials across several therapeutic areas including cardiovascular, oncology and neuroscience. (xtalks.com)

In 1984 he became the Chief of Cardiology at the National Naval Medical Center and was appointed as the Senior Cardiovascular Advisor to the Surgeon General. (xtalks.com)

Integrating strategies for road safety and noncommunicable diseases (NCDs) has proved beneficial in a number of countries. (who.int)

The results described in this paper indicate that mercury exposure, even at low doses, affects endothelial and cardiovascular function. (hindawi.com)

Anatomy1

Diseases3

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Phenomena and Processes3

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture2

Information Science2

Health Care28

Geographicals1

Outcomes11

Increased cardiovascular risk4

Hypertension9

Diabetes10

Patients23

Mortality6

Major adverse cardiovascular events4

20213

Events13

Efficacy5

Stroke2

Intervention2

Cardiologists2

Magnetic Resonance2

Association with cardiovascular2

Comparative cardiovascular1

Prevention5

Diseases are the lead1

Incidence3

Obesity1

Risk factors7

Inhibitors2

Composite cardiovascular3

Additional cardiovascular1

Health12

Cardiac2

Cancer2

Blood vessels6

Statin1

Risks3

Arterial2

Populations1

Therapies3

Complications1

Coronary artery1

Thoracic1

Glimepiride1

Cardiologist1

Outcome trials1

Internal Medicine2

Heart10

Deaths3

Adults1

Study3

Trials2

Surgeon General1

Beneficial1

Doses1