• Here, 15 German research institutions want to jointly advance personalized risk assessment for cardiovascular diseases and improve the prevention, diagnosis and therapy of these diseases. (innovations-report.com)
  • Risk parameters for cardiovascular diseases include blood pressure, blood sugar, tobacco consumption, cholesterol and body weight. (innovations-report.com)
  • With the data, a better individual risk assessment for diseases is possible. (innovations-report.com)
  • With the help of artificial intelligence, patterns are to be recognized and information obtained that doctors can use to improve the prevention, diagnosis and treatment of diseases of the cardiovascular system. (innovations-report.com)
  • Although the project is about cardiovascular diseases, the approach and experience can certainly be transferred to other clinical subjects," Professor Bavendiek is certain. (innovations-report.com)
  • These new risk charts, specifically calibrated for each country, remove major obstacles in applying risk-based strategies to prevent cardiovascular diseases," said Goodarz Danaei , assistant professor of global health at Harvard Chan School and senior author of the paper. (harvard.edu)
  • Cardiovascular diseases are the leading cause of death and disability worldwide, and more than three-quarters of CVD-related deaths occur in low- and middle-income countries. (harvard.edu)
  • Simulations and models are used to provide insights into infectious disease trends, quantify likely benefits of public health interventions, and support risk assessment for emerging infectious diseases. (edu.au)
  • Oral contraceptives (OC) modulate the risk for developing cardiovascular (CV) diseases. (maastrichtuniversity.nl)
  • This may open up new opportunities for improving outcomes in people at high risk for cardiovascular diseases (who have normal low-density lipoprotein cholesterol) by reducing IPFD. (bvsalud.org)
  • The development of the Chronic Care Model (CCM) for the care of patients with chronic diseases has focused on the integration of taking charge of the patient and his family within primary care. (intechopen.com)
  • A full pipeline of diagnosis and prognosis the risk of chronic diseases using deep learning and Shapley values: The Ravansar county anthropometric cohort study. (cdc.gov)
  • Physical activity is essential for preventing and controlling risk factors and chronic diseases, such as diabetes, high blood pressure (HBP), cardiovascular disease (CVD), obesity, cancer, and depression (1). (cdc.gov)
  • No studies to date have evaluated the association between feeling comfortable visiting a park and the risk of chronic diseases such as HBP. (cdc.gov)
  • The aim of this study was to determine the mortality burden of cardiovascular and respiratory diseases, specifically, the relative risk due to air pollution and the economic valuation derived from life-years lost within the population of São Paulo, Brazil. (aaqr.org)
  • Impaired fibrinolysis may be responsible for the increased risk of cardiovascular diseases in women with PCOS. (unboundmedicine.com)
  • In the Region, 94% of deaths related to exposure to air pollutants are due to noncommunicable diseases - notably cardiovascular diseases, stroke, chronic obstructive pulmonary disease and lung cancer. (who.int)
  • Many cardiovascular diseases evolve from a phenomenon called atherosclerosis. (lu.se)
  • This marker measures the thickness of the wall of the carotid arteries and can predict the possibility of developing cardiovascular diseases later on in life. (lu.se)
  • Stroke, like many other cardiovascular diseases, can be influenced by modifiable lifestyle factors, such as diet. (lu.se)
  • Strengths of associations and discrimination statistics suggested that WHR was the best predictor of cardiovascular events and mortality in patients with type-2 diabetes and BMI the worst. (nih.gov)
  • 1 In Spain, although cardiovascular mortality has been decreasing in the last 15 years, it continues to be the main cause of death among the national population. (revespcardiol.org)
  • Established and Emerging Lipid-Lowering Drugs for CVD Prevention This review summarizes the mechanisms of action, side effects, effect on blood lipids, and reduction in cardiovascular morbidity and mortality of both established and emerging lipid-lowering drugs. (medscape.com)
  • We hypothesised that long term intake of low or high calcium increases the risk of cardiovascular mortality. (bmj.com)
  • We investigated associations between long term dietary and supplemental intake of calcium with all cause mortality as well as with cardiovascular mortality in a large population based prospective study of Swedish women. (bmj.com)
  • Cox models were used to examine the association of lipids and inflammation with the risk of CVD and mortality, adjusting for age, sex and year of RA incidence. (bmj.com)
  • However, the association of a previous psychiatric diagnosis of anxiety or depression, or only such self-reported symptoms, with cardiovascular outcomes and mortality post-MI has not been previously examined in the same nationwide cohort. (lu.se)
  • Both acute and long-term exposure to elevated levels of ozone in air are associated with negative health effects ranging from increased morbidity and mortality due to respiratory and cardiovascular disease (Crouse et al. (cdc.gov)
  • Several studies suggest that the cardiovascular disease (CVD) mortality rates of persons with type 2 diabetes are about two to four times higher than those of the general population. (intechopen.com)
  • The results showed an association between PM 10 and cardiovascular and respiratory mortality, lagging 3 days. (aaqr.org)
  • This analysis also applies to patients with metabolic syndrome, a cluster of risk factors shown to be associated with an increased risk for T2D, cardiovascular disease and mortality. (nutfruit.org)
  • Cardiovascular disease remains one of the greatest causes of disease and mortality worldwide. (lu.se)
  • Although the receiver operating characteristic curve could not differentiate between anthropometric variables (P values 0.24), the relative integrated discrimination improvement statistic showed an enhancement in the discrimination capabilities of models using WHR for cardiovascular outcomes, except for cerebrovascular events. (nih.gov)
  • UKPDS-modelling of cardiovascular risk assessment and lifetime simulation of outcomes. (ox.ac.uk)
  • Equations were developed, combined and incorporated into the UKPDS Risk Engine and the UKPDS Outcomes models. (ox.ac.uk)
  • These models contribute to the estimation of risk and/or health outcomes adjusted for quality of life for use by, amongst others, clinicians, trialists, health planners, guideline developers and health economists. (ox.ac.uk)
  • Cardiac rehabilitation is a comprehensive secondary prevention program designed to reduce CVD complications risk and improve patient outcomes. (biomedcentral.com)
  • Contrarily, a lack of effective PE can result in a series of adverse outcomes, such as frequent requests for healthcare services due to the complications of the underlying condition, increased healthcare-related costs, and a higher risk of affliction by chronic conditions [ 7 ]. (biomedcentral.com)
  • Some studies indicate that proximity to green spaces is linked to a lower risk of HBP, improved diabetes outcomes, and reduced obesity (4-8). (cdc.gov)
  • Therefore, understanding the dietary risk factors for cardiovascular outcomes is important in order to establish nutritional recommendations. (lu.se)
  • Large studies with long-term follow-up confirmed the utility of CACS as a predictor of cardiovascular risk in populations. (bmj.com)
  • 26 remained an independent predictor of cardiovascular event risk at 180 days when adjusted for the Seattle Heart Failure Model Score and the Charlson comorbidity index (hazard ratio 1.7, 95% confidence interval 1.1 to 2.6, p = 0.03). (edu.au)
  • In epidemiology, generalized linear models are the main statistical methods used to explore associations. (aaem.pl)
  • The researchers studied nearly 5,000 proteins in 2,667 participants with CKD from the Chronic Renal Insufficiency Cohort (CRIC) and the Atherosclerosis Risk in Communities (ARIC) cohort. (news-medical.net)
  • This review highlights the link between eGFR reduction and that of atherosclerosis progression, which increases the risk of adverse cardiovascular events. (minervamedica.it)
  • Furthermore, identifying new biomarkers of cardiovascular risk has the potential to refine early-life prevention strategies, before atherosclerosis becomes established. (bmj.com)
  • Obesity also increases risks of cardiovascular disease, diabetes, atherosclerosis & hypertension according to Lazarou and Kouter (2010). (nmmra.org)
  • Using clinical, epidemiological, statistical and economics methods, UKPDS investigators developed mathematical models that helped define predictors (risk factors) for cardiovascular disease including angina, myocardial infarction, stroke, peripheral vascular disease and death in Type 2 diabetes. (ox.ac.uk)
  • The ZAHARA I (Zwangerschap bij Aangeboren HARtAfwijkingen I) and CARPREG (CARdiac disease in PREGnancy) risk scores were calculated for each pregnancy, as was the total number of cardiovascular (TPc) or offspring risk predictors (TPo) from these and other studies combined. (eur.nl)
  • An integrated risk factor approach is one that combines the effect of conventional risk predictors and non-invasive carotid ultrasound image-based phenotypes. (minervamedica.it)
  • CONCLUSIONS: Being waterpipe and/or cigarette smoker and DDT were the independent predictors of the number of traffic crashes in Poisson regression model. (who.int)
  • Individuals with sensitivity to blood lipids, and blood pressure associated predictors were at higher risk to develop cardiometabolic disease. (lu.se)
  • Although known principally as a clinical trial, the UK Prospective Diabetes Study (UKPDS) provided longitudinal data which helped define the natural history of cardiovascular complications in Type 2 diabetes. (ox.ac.uk)
  • Participants were excluded if they met any of the following criteria: endocrinal causes of obesity like Cushing's syndrome, very high risk of anesthetic complications like ASA grade IV, or severe psychiatric disorders like schizophrenia. (biomedcentral.com)
  • Management of chronic kidney disease includes reducing the patient's risk of CKD progression and risk of associated complications such as cardiovascular disease, acute kidney injury (AKI), CKD anemia, CKD metabolic acidosis, as well as CKD mineral and bone disorder. (kidney.org)
  • In Paper IV, we conducted a systematic review and metanalysis of observational studies, complemented by Mendelian randomization analysis using GWAS summary statistics, investigating causal associations of individuals with high, yet normal, glycaemia associated with cardiovascular complications. (lu.se)
  • Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. (bmj.com)
  • Cardiovascular disorders (CVD) account for about one-third of the global deaths. (biomedcentral.com)
  • Cardiovascular disease (CVD) refers to a group of cardiovascular disorders and is currently the first leading cause of death worldwide. (biomedcentral.com)
  • Such techniques could make it easier to visualize (patho)physiologic processes and mechanisms, increasing the range of CMR indications in a variety of cardiovascular disorders. (diagnosticimaging.com)
  • Chronic kidney disease (CKD) is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. (news-medical.net)
  • Bariatric surgery can alleviate cardiovascular risk via effects on cardiovascular disease (CVD) risk factors such as diabetes mellitus, hypertension, and dyslipidemia. (biomedcentral.com)
  • Conventional risk factors, such as smoking, hypertension, and hypercholesterolemia also predict CHD events in diabetic subjects ( 2 , 3 ). (diabetesjournals.org)
  • male ≥50 years of age or female ≥60 years of age with one additional risk factor (low HDL, impaired glucose tolerance, high waist circumference, smoker, hypertension), or presence of a risk modifier (e.g. (therapeuticresearch.com)
  • The CVD risk was estimated using two risk prediction tools: the American Heart Association and the American College of Cardiology (AHA/ACC) risk calculator and the World Health Organization/International Society of Hypertension (WHO/ISH) CVD risk prediction charts for the Eastern Mediterranean region. (qscience.com)
  • Based on the AHA/ACC risk scores, among those with a high CVD risk, almost two-thirds had CVD modifiable risk factors (i.e., smoking, diabetes, dyslipidemia, and hypertension). (qscience.com)
  • Assessment of estimated glomerular filtration rate and albuminuria should be performed for persons with diabetes and/or hypertension but is not recommended for the general population. (kidney.org)
  • It is estimated that by 2035 there will be almost 600 million people living with T2D and almost 900 million people with pre-diabetes, a silent state associated with a high risk of several deadly conditions including T2D, heart disease, hypertension, strokes and early death. (nutfruit.org)
  • A 10-year non-laboratory-based risk prediction chart was developed for fatal and non-fatal CVD using Cox Proportional Hazard regression. (irancohorts.ir)
  • Both non-laboratory and laboratory risk prediction models showed good discrimination in the external validation, with Harrell's C of 0.77 (95% CI 0.75-0.78) and 0.78 (95% CI 0.76-0.79), respectively. (irancohorts.ir)
  • Objectives Adequate prepregnancy prediction of maternal cardiovascular and offspring risk is important for counselling and management of pregnancy in women with congenital heart disease (CHD). (eur.nl)
  • None of the offspring prediction models perform adequately in our cohort. (eur.nl)
  • In general, CVD risk assessments are performed using conventional risk prediction models. (minervamedica.it)
  • National and international guidelines recommend that physicians use risk prediction equations, usually in the form of risk charts, to predict which of their patients are at high risk for heart disease and stroke, and to suggest lifestyle modification or prescribe medication to lower their risk. (harvard.edu)
  • The researchers set out to provide CVD risk prediction models geared toward each country. (harvard.edu)
  • The study found that, between 85% and 99% of the time, the office-based risk prediction model worked as well as the laboratory-based model in characterizing CVD risk. (harvard.edu)
  • D'Agostino was instrumental in developing several risk prediction models including, a global cardiovascular disease risk function, a coronary heart disease risk assessment function, an instrument for predicting acute ischemic heart disease, and a stroke health risk appraisal function. (wikipedia.org)
  • Approximately one-third of the cohort (33%) were classified as high risk using the AHA/ACC risk calculator, and 13.3% were classified as intermediate to high risk using the WHO/ISH CVD risk prediction charts. (qscience.com)
  • The WHO/ISH CVD risk prediction charts appeared to underestimate CVD risk, particularly for those identified as high risk using the AHA/ACC risk calculator. (qscience.com)
  • We and others have previously developed and validated HIV risk prediction models to identify PrEP candidates using electronic health records data. (cdc.gov)
  • In the current study, we convened focus groups with PCPs to elicit their perspectives on using prediction models to identify PrEP candidates in clinical practice. (cdc.gov)
  • PCPs were receptive to using prediction models to identify PrEP candidates. (cdc.gov)
  • In preparation for implementation in clinical settings, we conducted a qualitative study with PCPs to learn their perspectives on using HIV risk prediction models to identify PrEP candidates in primary care. (cdc.gov)
  • thoughts on implementation of a machine learning algorithm driven by EHR data, how they would prefer to receive clinical alerts generated by HIV risk prediction models, and the supports providers would need to act upon alerts. (cdc.gov)
  • 5 Two large studies have shown that people with both low eGFR and high ACR have increased risk of cardiovascular events and death. (kidney.org)
  • 26 is associated with increased risk of cardiovascular events at 180 days. (edu.au)
  • Those specific proteins were determined to best help indicate a patient's risk level of heart attack, heart failure, stroke, or even cardiovascular death in those with CKD. (news-medical.net)
  • The researchers produced the first set of risk charts for 182 countries to predict future risk of fatal and non-fatal CVD events, including heart attack and stroke. (harvard.edu)
  • Co-existing intracranial and extracranial carotid artery plaques are prevalent in symptomatic patients and the number of co-existing plaques is independently associated with the risk of recurrent stroke. (nih.gov)
  • Main outcome measures Primary outcome measures, identified from registry data, were time to death from all causes (n=11 944) and cause specific cardiovascular disease (n=3862), ischaemic heart disease (n=1932), and stroke (n=1100). (bmj.com)
  • Compared with intakes between 600 and 1000 mg/day, intakes above 1400 mg/day were associated with higher death rates from all causes (hazard ratio 1.40, 95% confidence interval 1.17 to 1.67), cardiovascular disease (1 49, 1.09 to 2.02), and ischaemic heart disease (2.14, 1.48 to 3.09) but not from stroke (0.73, 0.33 to 1.65). (bmj.com)
  • Conclusion High intakes of calcium in women are associated with higher death rates from all causes and cardiovascular disease but not from stroke. (bmj.com)
  • 6 7 Worryingly, three recent reanalyses of randomised trials in women have indicated a higher risk of both ischemic heart disease and stroke with calcium supplements, 8 9 10 a pattern not observed in a reanalysis of another randomised trial. (bmj.com)
  • One of the most dangerous presentations of cardiovascular disease is stroke. (lu.se)
  • My third study, analysed the risk of developing stroke within the context of dietary patterns considered healthy. (lu.se)
  • Despite the disease's prevalence-;10 percent of individuals across the globe suffer from CKD-;there are limited tools for measuring cardiac risk for CKD patients, until now. (news-medical.net)
  • A new proteomic risk model for cardiovascular disease was found to be more accurate than current methods of measuring cardiac risk, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. (news-medical.net)
  • The team, from Penn, Johns Hopkins, and the University of California San Francisco, used a drop of blood from participants to predict a patient's risk for a cardiac event. (news-medical.net)
  • Not only did the study indicate this model was more accurate compared to current approaches, the researchers were able to identify several proteins, like cartilage intermediate layer protein 2 (CILP2), that can be used in future research to identify cardiac risk or be the target for novel therapies. (news-medical.net)
  • Cardiac imaging is central to the diagnosis and risk stratification of coronary artery disease, beyond symptoms and clinical risk factors, by providing objective evidence of myocardial ischaemia and characterisation of coronary artery plaque. (bmj.com)
  • New cardiac CT techniques can assess coronary artery inflammation by imaging perivascular fat, and this may represent an important step forward in identifying the 'residual risk' that is not detected by plaque or ischaemia imaging. (bmj.com)
  • Cardiac CT (CCT) imaging has transformed the detection, characterisation and stratification of coronary artery disease (CAD) risk in individuals. (bmj.com)
  • Background: Over 90,000 rescue and recovery responders to the September 2001 World Trade Center (WTC) attacks were exposed to toxic materials that can impair cardiac function and increase cardiovascular disease (CVD) risk. (cdc.gov)
  • Only cardiac troponin, and to some degree also B-type natriuretic peptides, is widely used in clinical practice for risk assessment. (degruyter.com)
  • These efforts hold great potential for basic cardiac research and clinical applications, with the ultimate goal being the advancement of cardiovascular imaging. (diagnosticimaging.com)
  • Data from the Isfahan Cohort Study (ICS), a population-based study among 6504 adults aged ≥ 35 years, followed-up for at least ten years was used for the non-laboratory-based model derivation. (irancohorts.ir)
  • A new, long term cohort study suggests that healthy lifestyle is associated with a lower risk for dementia among people considered at lower and intermediate genetic risk but not for those considered at high genetic risk. (cdc.gov)
  • In our August 14, 2019 blog , we discussed the findings from a July 2019 JAMA article describing a large retrospective, cohort study of 196,383 in the UK Biobank which found that a healthy lifestyle is associated with a lower risk for dementia regardless of genetic risk. (cdc.gov)
  • Insulin resistance and beta-cell function were calculated by homeostasis model assessment (HOMA). (maastrichtuniversity.nl)
  • The insulin resistance syndrome (IRS), which is characterized by hyperinsulinemia, glucose intolerance, hypertriglyceridemia, low HDL cholesterol level, elevated blood pressure, and central obesity, accompanies the majority of cases of type 2 diabetes and has been suggested to be one of the links between diabetes and an excess risk of CHD. (diabetesjournals.org)
  • Emerging data show that high density lipoprotein cholesterol levels, an established negative risk factor for cardiovascular disease improves after bariatric surgery [ 9 ]. (biomedcentral.com)
  • An adverse lipid profile or dyslipidaemia is an important risk factor for cardiovascular disease (CVD) in the general population. (bmj.com)
  • This should facilitate clinical work in the future and create a new data set that is comparable across all sites, enabling more accurate risk assessments and detailed analyses for improving patient care and scientific projects. (innovations-report.com)
  • Coronary artery disease risk assessment that incorporates clinical factors, plaque characteristics and perivascular inflammation offers a more comprehensive individualised approach to quantify and stratify coronary artery disease risk, with potential healthcare benefits for prevention, diagnosis and treatment recommendations. (bmj.com)
  • In this review, we introduce the concept of computational fluid dynamics (CFD) modeling with a clinical perspective and we review the CFD models used to study RE from the fluid mechanics point of view. (unav.edu)
  • Cardiovascular MR (CMR) has evolved rapidly over the past decade, with the results feeding into a broad spectrum of clinical and research applications. (diagnosticimaging.com)
  • The development of faster CMR techniques and advanced MR hardware is largely driven by the need to overcome physiological constraints inherent in clinical cardiovascular imaging, such as motion and blood flow. (diagnosticimaging.com)
  • In conjunction with a non-high clinical pretest probability (PTP) assessment model. (siemens-healthineers.com)
  • The models have high predictive performance and can be used to alert clinicians about patients who merit clinical evaluations for PrEP. (cdc.gov)
  • However, coronary artery disease risk is also driven by biological processes, such as inflammation, that are not fully reflected by severity of stenosis, myocardial ischaemia or by coronary plaque features. (bmj.com)
  • The ability to personalize risk assessment for individual patients with CKD is the first step toward scaling this for larger health systems. (news-medical.net)
  • The reliable identification of such high-risk individuals with no prior history of cardiovascular disease will undoubtedly be of great interest to patients and their providers for preventative care measures. (news-medical.net)
  • Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)
  • Results Across all the 1 267 159 patients in the validation dataset, the 50th, 75th, 90th, and 95th centile values for lifetime risk were 31%, 39%, 50%, and 57% respectively. (bmj.com)
  • Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
  • Patients identified as high risk with the lifetime risk approach were more likely to be younger, male, from ethnic minority groups, and have a positive family history of premature coronary heart disease than those identified with the 10 year QRISK2 score. (bmj.com)
  • Conclusions Compared with using a 10 year QRISK2 score, a lifetime risk score will tend to identify patients for intervention at a younger age. (bmj.com)
  • 1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
  • Applying this 20% risk threshold for intervention may not identify younger patients who, because of their age, have a low absolute 10 year risk but who have a high relative risk compared with their peers. (bmj.com)
  • Some argue that younger patients with an adverse risk profile may have more to gain during their lifetime if interventions are started at a younger age rather than waiting until they cross the 20% threshold. (bmj.com)
  • We here at the MHH Clinic for Cardiology and Angiology want to record the risk parameters directly when patients take their medical history," explains Professor Bavendiek. (innovations-report.com)
  • BACKGROUND: Clinicians who are using the Framingham Risk Score (FRS) or the American College of Cardiology/American Heart Association Pooled Cohort Equations (PCE) to estimate risk for their patients based on electronic health data (EHD) face 4 questions. (healthpartners.com)
  • The non-laboratory model was in agreement and classified high risk and low risk patients as accurately as the laboratory one. (irancohorts.ir)
  • This review examined the approaches used for CVD risk assessments in CKD patients using the concept of integrated risk factors. (minervamedica.it)
  • Furthermore, this review provided insights into novel artificial intelligence methods, such as machine learning and deep learning algorithms, to carry out accurate and automated CVD risk assessments and survival analyses in patients with CKD. (minervamedica.it)
  • Boston, MA - A new study led by Harvard T.H. Chan School of Public Health researchers provides powerful new tools to help clinicians around the globe predict their patients' 10-year risk of cardiovascular disease (CVD) . (harvard.edu)
  • However, among diabetes patients, the office-based model underestimated the risk noticeably. (harvard.edu)
  • Very low or zero CACS is reassuring and clinically valuable, but age and other prevalent risk factors are major drivers of CACS, 1 such that most middle-aged or older patients in higher cardiovascular risk groups have elevated CACS. (bmj.com)
  • All patients underwent cardiovascular magnetic resonance (CMR) for brain and intracranial and extracranial arteries. (nih.gov)
  • Dynamic Risk Assessment for HCC in Patients With Chronic HCV The authors developed a model for identifying hepatocellular carcinoma risk factors in individuals with chronic HCV, across antiviral treatment status and interactions with cirrhosis. (medscape.com)
  • 3 4 The evidence for an excess cardiovascular risk in patients with rheumatoid arthritis (RA) is convincing. (bmj.com)
  • Background: Depression and anxiety are risk factors for patients with myocardial infarction (MI). (lu.se)
  • After multiple imputation, we applied Cox regression to estimate the post-MI outcome risk for patients with a previous psychiatric diagnosis of anxiety/depression (Diagnosis), patients with no formal. (lu.se)
  • After multiple imputation, we applied Cox regression to estimate the post-MI outcome risk for patients with a previous psychiatric diagnosis of anxiety/depression (Diagnosis), patients with no formal diagnosis but self-reported symptoms of anxiety/depression (Symptoms), versus patients with neither Diagnosis nor Symptoms (Reference). (lu.se)
  • Assessment of both psychiatric history and self-reported symptoms seems warranted for these patients. (lu.se)
  • Recheck every five years in patients 40 to 75 years of age or when patient health status changes such that a change in risk level is expected. (therapeuticresearch.com)
  • All high-risk patients (FRS 10-year risk ≥20%), and patients with a statin-indicated condition (above) with the following caveat regarding CKD: treat those age ≥50 years and not on dialysis. (therapeuticresearch.com)
  • These patients are essentially intermediate-risk patients. (therapeuticresearch.com)
  • Results: Of the 346 eligible patients, 28% (n = 97) had obtainable data for the estimation of their CVD risk using both tools. (qscience.com)
  • A closer alliance between psychiatrists and primary healthcare professionals to control modifiable cardiovascular risk factors among patients with SMI is necessary. (qscience.com)
  • This qualitative study involved 30 adult patients with cardiovascular disease who were hospitalized or had a history of hospitalization. (biomedcentral.com)
  • Identifying patients at increased risk for HIV acquisition can be challenging. (cdc.gov)
  • PCPs believed that models could facilitate patient-provider communication about HIV risk, destigmatize and standardize HIV risk assessments, help patients accurately perceive their risk, and identify PrEP candidates who might otherwise be missed. (cdc.gov)
  • Likewise, people who smoke, black males, and patients who consume a diet high in animal fat or in chromium are at increased risk for this disease. (medscape.com)
  • As in Hannover, IT structures are being created at all participating sites in which data can be stored in such a way that the same automated risk assessments and complex analyses will ultimately be possible across all sites. (innovations-report.com)
  • In covariate-adjusted analyses, men's CVD 9/11/2001 arrival risks were 1.40 (95% confidence interval [CI] = 1.26, 1.56) and 1.43 (95% CI = 1.29, 1.58) and women's were 2.16 (95% CI = 1.49, 3.11) and 1.59 (95% CI = 1.11, 2.27) with and without dust cloud exposure, respectively. (cdc.gov)
  • Using structural equation modelling, the mediation analyses enhanced with Mendelian randomization analysis, showed a likely causal putative association between carbohydrate intake and T2D. (lu.se)
  • In the United States, race and socioeconomic status (SES) are risk factors for cardiovascular disease, and Black residents and those of lower SES have higher rates of HBP (14-16). (cdc.gov)
  • Of those thousands of proteins evaluated, researchers used machine learning methods to choose 32 proteins that comprised their proteomic risk model. (news-medical.net)
  • However, the use of other methods such as Structural Equation Modelling (SEM) is gradually increasing. (aaem.pl)
  • Methods In a population-based RA incident cohort (1987 American College of Rheumatology criteria first met between 1988 and 2007), details were collected of serum lipid measures, erythrocyte sedimentation rates (ESRs), C-reactive protein (CRP) measures and cardiovascular events, including ischaemic heart disease and heart failure. (bmj.com)
  • RESEARCH DESIGN AND METHODS -Clustering of cardiovascular risk factors was analyzed by factor analysis. (diabetesjournals.org)
  • Furthermore, intercorrelated risk factors typical of IRS are not readily studied by conventional statistical methods. (diabetesjournals.org)
  • Recently, factor analysis and principal components analysis, statistical methods for studies of intercorrelating variables, have been applied to investigate the clustering of cardiovascular risk factors in both nondiabetic and diabetic subjects ( 4 , 5 , 6 , 7 ). (diabetesjournals.org)
  • Air pollution also increases the risk for acute respiratory infections. (who.int)
  • Identifying risk factors for erectile dysfunction, including as smoking, obesity, sedentary lifestyle, and persistent alcohol intake, is crucial for preventing erectile dysfunction ( 6 - 8 ). (frontiersin.org)
  • Our study aimed to assess the cholesterol efflux capacity (CEC) of HDL as a negative risk factor for CVD in individuals with obesity and identify the factors associated with improvement in CEC 3 months following bariatric surgery. (biomedcentral.com)
  • The results suggest that improvements in CEC, through improvement in adipose tissue health in terms of adipokine secretion and insulin sensitivity could be an important pathway in modulating obesity-related CVD risk. (biomedcentral.com)
  • The study included 56 individuals with obesity, of whom 30 individuals underwent Roux-en-Y gastric bypass surgery (RYGB) and twenty-six underwent sleeve gastrectomy (SG). (biomedcentral.com)
  • Introduction: Individuals with serious mental illness (SMI) experience premature death, likely due to increased rates of obesity and cardiovascular disease (CVD). (qscience.com)
  • All participants had CKD and no history of cardiovascular disease at study baseline. (news-medical.net)
  • The UKPDS made clearer the contributions to risk of age, hyperglycaemia, elevated blood pressure, adverse blood lipids and smoking. (ox.ac.uk)
  • Typically, blood tests are necessary to measure CVD risk factors such as blood sugar and lipids . (harvard.edu)
  • But identifying those at high risk of having a future cardiovascular event can be difficult in many countries because there are no reliable risk charts, and because calculating risk typically relies on measurements of blood sugar and lipids-which, in resource-poor settings, can make the assessment too costly or impractical. (harvard.edu)
  • Objective To examine the impact of systemic inflammation and serum lipids on cardiovascular disease (CVD) in rheumatoid arthritis (RA). (bmj.com)
  • Lipids may have paradoxical associations with the risk of CVD in RA, whereby lower TCh and LDL levels are associated with increased cardiovascular risk. (bmj.com)
  • 5 , - , 7 However, the association between lipids and cardiovascular risk in RA appears to be more complex than in the general population, with systemic inflammation being a notable contributor to the lipid profile changes. (bmj.com)
  • This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. (lu.se)
  • Acute exposure to elevated levels of PM2.5 can lead to irritation of eyes, nose, throat and lungs , and increases relative risk of acute cardiovascular events including admission to a hospital for stoke (Rajagopalan et al. (cdc.gov)
  • Conclusions: Both a previous diagnosis, and present self-reported symptoms of anxiety or depression are associated with an increased risk of death and recurrent cardiovascular events in adults with first-time MI. (lu.se)
  • This study provides valuable information about the problems of patient education for adults with cardiovascular disease. (biomedcentral.com)
  • Of the estimated thirty million American adults with CKD, over 80% are unaware of the condition that increases risk for cardiovascular events and progression to kidney failure and death. (kidney.org)
  • 2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults. (siemens-healthineers.com)
  • The aim of this systematic review and meta-analysis was to analyze the effect of mobile-based health interventions for reducing cardiometabolic risk through the promotion of physical activity and healthy lifestyle behaviors. (jmir.org)
  • PubMed, Scopus, Web of Science, Cochrane Central Register of Controlled Trials, and SPORTdiscus databases were searched for experimental studies evaluating cardiometabolic risk indicators among individuals with metabolic syndrome who were included in technology-assisted physical activity and lifestyle interventions. (jmir.org)
  • Overall, mobile-based health interventions aimed at promoting physical activity and healthy lifestyle changes had a strong positive effect on cardiometabolic risk indicators among individuals with metabolic syndrome. (jmir.org)
  • This new model was found to be more accurate in identifying those at risk of future cardiovascular disease, as compared to both the 2013 ACC/AHA Pooled Cohort Equation (PCE)-;which provides a set of guidelines for best practices in measuring cardiovascular risk-;and a modified PCE that included estimated glomerular filtrate rate (eGFR). (news-medical.net)
  • Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
  • Four linear regression models (LRMs) and two SEMs were run to estimate the effect of prenatal exposure to inorganic arsenic on cortisol concentration in infants. (aaem.pl)
  • This study was conducted to estimate the CVD risk in a cohort of individuals with SMI receiving outpatient psychiatric services in Qatar and to assess contributory CVD risk factors. (qscience.com)
  • In autumn 2009 I took up my current position as Reader in Cardiovascular Imaging and Centre Lead in the new Advanced Cardiovascular Imaging Centre funded through the NIHR Cardiovascular Biomedical Research Unit. (researchgate.net)
  • After adjustment, hazard ratio (95% CI) for WC were 1.10 (1.03-1.18) for cardiovascular events, 1.13 (1.03-1.24) for coronary events, and 1.08 (0.98-1.19) for cardiovascular deaths. (nih.gov)
  • Objectives To assess the feasibility of extracting radiomics signal intensity based features from the myocardium using cardiovascular magnetic resonance (CMR) imaging stress perfusion sequences. (researchgate.net)
  • Cox regression models were used to investigate whether these clusters (factors) predict CHD events (CHD death or nonfatal myocardial infarction) during a 7-year follow-up in 229 type 2 diabetic subjects aged 65-74 years. (diabetesjournals.org)
  • Objective To investigate the association between long term intake of dietary and supplemental calcium and death from all causes and cardiovascular disease. (bmj.com)
  • OBJECTIVE -To investigate whether cardiovascular risk factors cluster with hyperinsulinemia in elderly type 2 diabetic subjects and, if so, whether this clustering predicts coronary heart disease (CHD) events during a 7-year follow-up. (diabetesjournals.org)
  • Association of low-level arsenic exposure in drinking water with cardiovascular disease: a systematic review and risk assessment. (aaem.pl)
  • Low-level arsenic exposure and developmental neurotoxicity in children: A systematic review and risk assessment. (aaem.pl)
  • However, since these conventional models were developed for a specific cohort with a unique risk profile and further these models do not consider atherosclerotic plaque-based phenotypes, therefore, such models can either underestimate or overestimate the risk of CVD events. (minervamedica.it)
  • Cardiovascular disease (CVD) events are responsible for more than 4 million deaths in Europe each year. (revespcardiol.org)
  • We sought to determine the influence of cognitive dysfunction, identified using the Montreal Cognitive Assessment (MoCA), on 180-day cardiovascular events. (edu.au)
  • It's good practice to check blood pressure, urinalysis and blood to rule out conditions such as cardiovascular and renal disease, diabetes, anaemia and check nutritional status (SIGN, 2010). (nmmra.org)
  • This study was conducted using a retrospective Health Impact Assessment (HIA) approach via daily time series of cardiovascular and respiratory deaths for the population of São Paulo from 2000 to 2011. (aaqr.org)
  • 3 Although these recommendations work for the general population, more intensive lifestyle efforts and the use of evidence-based preventive pharmacotherapy (ie, statins) should be prescribed for persons at high risk of atherosclerotic CVD, since, in this case, the benefits of medical therapy outweigh the risk of any adverse effects. (revespcardiol.org)
  • Tehran Lipid and Glucose Study (TLGS) data was used to evaluate the external validity of both non-laboratory and laboratory risk assessment models in other populations rather than one used in the model derivation. (irancohorts.ir)
  • The collected data were analyzed using a logistic regression model. (bvsalud.org)
  • 2022). The approach taken here to quantify cumulative environmental burden includes assessments of both features of the environment that contribute to good health (salutogenic features) and features of the environment that may be detrimental to human health (pathogenic features). (cdc.gov)
  • Air pollution is an important health risk concern and an economic burden, notably on low- and middle-income countries. (aaqr.org)
  • This new model is a step forward towards more accurate estimates of the regional burden from exposure to indoor and outdoor air pollution. (who.int)
  • Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)
  • The aim of this study was to compare the strength of associations and discrimination capability of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) with cardiovascular disease risk in individuals with type-2 diabetes. (nih.gov)
  • For example, the UKPDS risk engine-version 2-estimates that a white 62-year-old man with 11 years of Type 2 diabetes, a glycated haemoglobin of 8.3%, a systolic blood pressure of 145 mmHg and total and high-density lipoprotein cholesterol values of 5.8 and 1.1 mmol/l who did not smoke has a 33% chance of having overt coronary heart disease within 10 years. (ox.ac.uk)
  • This indicates that conventional CHD risk factors cannot explain the excess risk of CHD in type 2 diabetes. (diabetesjournals.org)
  • We found that those adhering to the EAT-Lancet diet had decreased risk of type 2 diabetes. (lu.se)
  • The Penn researchers developed a model using proteomics, the large scale study of proteins. (news-medical.net)
  • To generate the models, researchers used data from eight long-term studies in the U.S. and recalibrated the models by using data on CVD risk factor levels and CVD rates for each target country. (harvard.edu)
  • A population health model for CKD including regular assessment, diagnosis, and early intervention has been shown to favorably impact CKD progression and downstream incidence of ESRD. (kidney.org)
  • Principles and Practice of Structural Equaiton Modelling. (aaem.pl)
  • The aim of the study was to illustrate the use of SEM in the assessment of salivary cortisol concentration in infants as a biomarker of perinatal exposure to inorganic arsenic. (aaem.pl)
  • Risk assessments using the Strain Index and the TLV for HAL, Part I: Task and multi-task job exposure classifications. (uwm.edu)
  • The Revised Strain Index: an improved upper extremity exposure assessment model. (uwm.edu)
  • We built a linear mixed-effect model including each of urinary PAH metabolites as the time-varying exposure variable of interest. (bvsalud.org)
  • HIV pre-exposure prophylaxis (PrEP) can decrease the risk of HIV acquisition by over 90% and is effective when prescribed in routine care settings. (cdc.gov)
  • Michael A. Stephens, Ralph B. D'Agostino) Mathematical Modeling: Applications in Emergency Health Services. (wikipedia.org)
  • I'm Commander Ibad Khan, and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
  • Cardiovascular disease is the leading cause of premature death and a major cause of disability in the UK. (bmj.com)
  • My research interest over the past few years focused on increasing the amount of evidence exploring the link between sugar consumption and disease development (particularly cardiovascular disease) in the context of nutritional recommendations. (lu.se)
  • For years, many nutritional recommendations for sugar intake used the risk of causing micronutrient dilution as a basis for their advice. (lu.se)