• Insulin sensitivity was assessed as rate of whole body glucose turnover (R g ) per animal plasma insulin level ( d ). (biomedcentral.com)
  • Insulin sensitivity in subjects with type 2 diabetes. (kaiserpermanente.org)
  • RESEARCH DESIGN AND METHODS: To examine this issue, we determined insulin sensitivity (SI) in 479 type 2 diabetic subjects by minimal model analyses of frequently sampled intravenous glucose tolerance tests in the Insulin Resistance Atherosclerosis Study (IRAS), a large multicenter study of insulin sensitivity and cardiovascular disease in African-Americans, Hispanics, and non-Hispanic whites. (kaiserpermanente.org)
  • failure of the signals or of the B cells to adapt adequately in relation to insulin sensitivity results in inappropriate insulin levels, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and type 2 diabetes. (medscape.com)
  • The gut bacteria known as Lachnospiraceae might have the ability to boost insulin sensitivity, potentially providing a protective barrier against diabetes. (medindia.net)
  • Studies have consistently shown that there is a link between insulin resistance and circadian rhythm, with insulin sensitivity being higher in the morning and lower in the evening. (wikipedia.org)
  • Based on the significant improvement in insulin sensitivity in humans after bariatric surgery and rats with surgical removal of the duodenum, it has been proposed that some substance is produced in the mucosa of that initial portion of the small intestine that signals body cells to become insulin resistant. (wikipedia.org)
  • If the producing tissue is removed, the signal ceases and body cells revert to normal insulin sensitivity. (wikipedia.org)
  • Traditionally, nuts have been considered a staple food, but because of their high energy and fat content are not considered good for body weight control or insulin sensitivity. (cambridge.org)
  • However, whether or not frequent consumption of nuts can cause weight gain and impair insulin sensitivity is not fully understood. (cambridge.org)
  • In the context of calorie-restricted diets, adding nuts produces a more lasting and greater magnitude of weight loss among obese subjects while improving insulin sensitivity. (cambridge.org)
  • Further studies are needed to clarify the effect of long-term (≥ year) consumption of nuts on body weight and their role in altering insulin sensitivity both in normal and type-2 diabetics. (cambridge.org)
  • It may provide the link between inflammation and insulin sensitivity. (lww.com)
  • In general the masters athlete should seek to maximize insulin sensitivity, as studies show that taking in carbohydrates in an insulin-resistant state can impede muscle growth. (ironmanmagazine.com)
  • Below are three dietary interventions for increasing insulin sensitivity and anabolism. (ironmanmagazine.com)
  • Research from Gabriel's lab at the University of Illinois, however, has demonstrated that lowering it to 1.5 grams of carb results in improved insulin sensitivity, fat loss and greater increases in muscle during training.9,10 Thus, we recommend eating no more than one to 1 1/2 grams of carbohydrates per gram of protein at a meal. (ironmanmagazine.com)
  • Poor insulin sensitivity ups your risk of heart disease and reduces how offended insulin will get if you challenge it to a rap battle. (greatist.com)
  • Eating less frequently is one way to help check your insulin sensitivity before it wrecks itself. (greatist.com)
  • Lee S, Bacha F, Hannon T, Kuk JL, Boesch C, Arslanian S " Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial. . (bcm.edu)
  • De Las Heras J, Lee S, Bacha F, Tfayli H, Arslanian S " Cross-Sectional Association between Blood Pressure, in vivo Insulin Sensitivity and Adiponectin in Overweight Adolescents. . (bcm.edu)
  • Burns SF, Bacha F, Lee SJ, Tfayli H, Gungor N, Arslanian SA " Declining {beta}-Cell Function Relative to Insulin Sensitivity With Escalating OGTT 2-h Glucose Concentrations in the Nondiabetic Through the Diabetic Range in Overweight Youth. . (bcm.edu)
  • Lee S, Bacha F, Gungor N, Arslanian SA " Cardiorespiratory fitness in youth: relationship to insulin sensitivity and beta-cell function. . (bcm.edu)
  • Bacha F, Saad R, Gungor N, Arslanian SA " Does adiponectin explain the lower insulin sensitivity and hyperinsulinemia of African-American children? . (bcm.edu)
  • Overweight youth are more susceptible to metabolic disorders, since the accumulation of body fat, especially in the abdominal region, generates an increase in fatty acids circulating in the bloodstream, which consequently impairs insulin signaling and leads to a reduction in sensitivity of receptors and tissue response to cellular actions that are mediated by this hormone 1,3,4 . (bvsalud.org)
  • This study aimed to evaluate the effects of metformin and conjugated linoleic acid (CLA) on insulin sensitivity, measured via euglycemic-hyperinsulinemic clamp technique and insulin pathway expression molecules in muscle biopsies of children with obesity. (medscape.com)
  • For insulin sensitivity Rd value (mg/kg/min), there was a statistically significant difference between the CLA vs placebo (6.53 ± 2.54 vs 5.05 ± 1.46, P = 0.035). (medscape.com)
  • After analysis of covariance was performed and the influence of body mass index, age, Tanner stage, prescribed diet, and fitness achievement was controlled, a clinically relevant effect size on insulin sensitivity remained evident in the CLA group (37%) and exceeded lifestyle program benefits. (medscape.com)
  • Improvement of insulin sensitivity, measured via euglycemic-hyperinsulinemic clamp and IRS2 upregulation, favored patients treated with CLA. (medscape.com)
  • Metformin (MET) is a biguanide used for the treatment of type 2 diabetes in children and adolescents due to its ability to decrease hepatic glucose production and increase peripheral insulin sensitivity. (medscape.com)
  • Recent studies on diseases which involve insulin insensitivity (e.g. obesity, type 2 diabetes and atherosclerosis) also show increased cytokine production and markers of inflammation. (lww.com)
  • The circulating levels of its precursor, pro-NT, predicts the presence and development of metabolic and cardiovascular diseases. (lu.se)
  • Findings from the World Health Organization's Monitor Trends in Cardiovascular Diseases (MONICA) project involving 21 countries showed a 4% fall in CAD death rates. (medscape.com)
  • Objectives The hypothesis of the study was that if the gut microbiota is involved in the development of atherosclerotic cardiovascular and cerebrovascular diseases (CVDs), total colectomy may reduce the long-term risk of CVDs. (bmj.com)
  • The major strength of the study is based on the availability of information in the entire Danish Patient Register from 1996 to 2014, which allows historical prospective assessment of the risk of new occurrences of cardiovascular and cerebrovascular diseases (CVDs) during long-term, essentially complete follow-up in patients after colectomy by comparison with matched patients that had undergone other types of surgery. (bmj.com)
  • Trans fats may increase inflammatory markers and the risk of chronic inflammation, which can lead to diseases such as diabetes and cardiovascular disease. (medicalnewstoday.com)
  • As you'll see from the reasons to avoid fizzy drinks below, sugar-filled fizzy drinks and sugary soft drinks can increase your risk of weight gain, poor dental health, and cardiovascular diseases. (hollandandbarrett.com)
  • In 2008, of the 57 million deaths that occurred globally, 36 million - almost two thirds - were due to NCDs, comprising mainly cardiovascular diseases, cancers, diabetes and chronic lung diseases. (who.int)
  • Abnormal lipid levels in young adults might be an early marker of atherosclerosis and cardiovascular diseases and our findings highlight the importance of conducting longitudinal studies in this population. (cdc.gov)
  • Type 2 diabetes, which is the most common form, can be life threatening due to its complications, particularly, cardiovascular diseases. (who.int)
  • In the African Region, efforts made to create an environment that enhances the fight against diabetes include adoption of resolutions AFR/RC50/R4 on noncommunicable diseases: strategy for the African Region, in 2000, and AFR/RC55/R4: cardiovascular diseases in the African Region, in 2005. (who.int)
  • Conversely, people with cardiovascular diseases more frequently suffer from serious mental disorders. (bvsalud.org)
  • The predisposing factors for the coexistence of mental illnesses and cardiovascular diseases are often entangled. (bvsalud.org)
  • Obesity is an increasing problem and the health care costs for cardiovascular disease, type 2 diabetes and other lifestyle-related diseases are rocketing. (lu.se)
  • In multivariable linear regression models, we found an interaction (P less than 0.05) between the ratio of saturated fat to carbohydrate intake as a continuous variable and PLIN1 11482G>A for HOMA-IR (homeostasis model assessment of insulin resistance) in women. (usda.gov)
  • By dichotomizing the ratio of saturated fat to carbohydrate intake into high and low, we found significant interaction terms for insulin and HOMA-IR (P less than 0.05). (usda.gov)
  • When the ratio of saturated fat to carbohydrate was high, insulin and HOMA-IR were higher in minor allele carriers (P=0.004 and P=0.003, respectively), but did not differ when the ratio was low. (usda.gov)
  • Conclusions: We found consistent acute and chronic benefits of chocolate or cocoa on FMD and previously unreported promising effects on insulin and HOMA-IR. (harvard.edu)
  • This study confirms that insulin resistance affects treatment outcome, and thus HOMA-IR testing before initiation of therapy may be a cost-effective tool. (who.int)
  • Then, we analyzed the effects on waist circumference, glucose, insulin, HOMA-IR index and uric acid compared to a control group of 19 overweight adolescents who did not receive any intervention. (bvsalud.org)
  • Ambient insulin levels, various physiologic and disease states, and drugs regulate insulin receptor concentration or affinity. (medscape.com)
  • Patients with metabolic syndrome (MetS) have an increased risk of cardiovascular disease. (biomedcentral.com)
  • IJD are associated with increased cardiovascular (CV) disease-related morbidity and mortality. (bmj.com)
  • 1 , 2 The majority of these deaths are attributed to atherosclerotic cardiovascular (CV) disease in particular. (bmj.com)
  • Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? (mja.com.au)
  • To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors. (mja.com.au)
  • The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. (mja.com.au)
  • The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study. (mja.com.au)
  • We should continue to use caution as indicated by the FDA label and only use testosterone therapy selectively in people who have true symptoms of hypogonadism," and be cautious about using it particularly in men at higher cardiovascular risk due to family history or known personal heart disease. (medscape.com)
  • Background: There is substantial interest in chocolate and flavan-3-ols for the prevention of cardiovascular disease (CVD). (harvard.edu)
  • Total cholesterol is an independent risk factor for cardiovascular disease. (ecopolitan.com)
  • Cardiovascular disease is one of the top killers in the U.S., especially among men. (lifelinescreening.com)
  • When the blood vessels get damaged enough, it inhibits the heart's ability to get blood throughout the body, resulting in cardiovascular disease. (lifelinescreening.com)
  • Obesity increases a person's risk for cardiovascular disease because it puts extra pressure on the blood vessels, constricting blood flow. (lifelinescreening.com)
  • How does cardiovascular disease increase the risk of a stroke? (lifelinescreening.com)
  • Those with cardiovascular disease have damaged blood vessels throughout the body - including vital ones like the aorta . (lifelinescreening.com)
  • Concerned about your risk for diabetes and cardiovascular disease? (lifelinescreening.com)
  • To assess risk for cardiovascular disease, patients undergo a painless and non-invasive ultrasound . (lifelinescreening.com)
  • Any early warning signs of cardiovascular disease can often be caught here before they progress into a more serious condition. (lifelinescreening.com)
  • 2018). Association between insulin resistance and the development of cardiovascular disease. (greatist.com)
  • Thus, through its effects on these and other variables, insulin resistance could be the underlying cause of much of coronary artery disease (CAD) ( 1 , 2 ). (diabetesjournals.org)
  • Wendy Frost, Advanced Dietitian in Paediatrics, reports on an audit amongst children with type 1 diabetes carried out with the aim of identifying those who are potentially more at risk of cardiovascular disease. (uk.com)
  • Children and young people with type 1 diabetes (T1D) are faced with an increased risk of developing cardiovascular disease (CVD). (uk.com)
  • The National Institute of Clinical Excellence (NICE) guidelines 1 recommend considering statin treatment for the primary prevention of cardiovascular disease in all adults with type 1 diabetes, and offering statin treatment to adults with type 1 diabetes who are older than 40 years of age or who have had diabetes for more than 10 years. (uk.com)
  • Children who have obesity are more likely to have high blood pressure and high cholesterol, which are risk factors for cardiovascular disease. (cdc.gov)
  • Having high values of one or more of these measures significantly increases one's risk for cardiovascular disease. (theconversation.com)
  • Moreover, a majority of the MHO population tends to progress towards "metabolically unhealthy obesity" or MUO over a number of years , leading to enhanced risk of diabetes, cardiovascular disease and other disorders linked with obesity. (theconversation.com)
  • They are better protected against diabetes and cardiovascular disease compared to people whose body fat is located more in the abdomen (apple-shaped). (theconversation.com)
  • The researchers concluded that a reduction in glycemic load may aid in the prevention or treatment of obesity, cardiovascular disease, and diabetes mellitus. (patrickholford.com)
  • Because of the potential adverse health outcomes associated with SSB intake, including obesity, type 2 diabetes, and cardiovascular disease, public health practitioners should continue efforts aimed at decreasing SSB intake among demographic groups with the highest reported consumption. (cdc.gov)
  • Among adults, frequent (i.e., at least once a day) SSB intake is associated with adverse health consequences, including obesity, type 2 diabetes, and cardiovascular disease ( 2 ). (cdc.gov)
  • Other genes that are associated with blood fat (lipid) levels, inflammation, and the cardiovascular and immune systems contribute significantly to longevity because they reduce the risk of heart disease (the main cause of death in older people), stroke, and insulin resistance. (medlineplus.gov)
  • The disease presents with metabolic anomalies characterized by chronic hyperglycaemia, resulting from defective secretion or action of insulin (insulin resistance) or both. (who.int)
  • Insulin resistance precedes metabolic syndrome abnormalities and may promote cardiovascular disease and type 2 diabetes in children with obesity. (medscape.com)
  • [ 1 ] Insulin resistance has been recognized as the main physiopathological event preceding metabolic syndrome abnormalities and may promote cardiovascular disease and type 2 diabetes in individuals with obesity. (medscape.com)
  • Lee S, Bacha F, Gungor N, Arslanian S " Comparison of different definitions of pediatric metabolic syndrome: relation to abdominal adiposity, insulin resistance, adiponectin, and inflammatory biomarkers. . (bcm.edu)
  • Heterogeneity analysis revealed that an increasing index of insulin resistance was independently associated with improving the performance of adiponectin upon metabolic syndrome diagnosis (ratio of diagnostic odds ratio = 3.89, 95% CI: 1.13-13.9). (frontiersin.org)
  • Certainly, great caution is advised regarding the use of testosterone replacement therapy in people with established atherosclerosis due to the findings of plaque progression in the testosterone trials and the excess cardiovascular events observed in the TOM trial, write Michos and fellow editorialist Matthew J. Budoff, MD, of UCLA, in their editorial. (medscape.com)
  • Une recherche documentaire a été effectuée dans PubMed de 1980 à 2021 en utilisant diverses combinaisons de termes MeSH comme tabac, diabète, hypertension, dyslipidémie, trouble dépressif majeur, trouble bipolaire, schizophrénie. (bvsalud.org)
  • Type 2 diabetes-led cardiovascular risk needs mandatory interdisciplinary, patient-centered care to reduce morbidity and mortality. (medindia.net)
  • Cardiovascular morbidity and mortality associated with the metabolic syndrome. (mja.com.au)
  • Bacha F, Saad R, Gungor N, Arslanian SA " Are obesity-related metabolic risk factors modulated by the degree of insulin resistance in adolescents? . (bcm.edu)
  • Insulin resistance (IR) and type 2 diabetes are becoming common among children and adolescents, are related to cardiometabolic risk and have been presented as a public health problem, requiring attention from the early stages of life 1,2 . (bvsalud.org)
  • Since diabetes is associated with cardiovascular and kidney complications, we investigated the influence of SBE on blood glucose, blood pressure and renal function in some experimental animal paradigms. (endocrine-abstracts.org)
  • Complications include cardiovascular disorders. (msdmanuals.com)
  • Vascular complications are greatest in T1D individuals with concomitant insulin resistance (IR), however, whether IR amplifies activiation of the lectin pathway in T1D is unknown. (bvsalud.org)
  • Diabetes is serious due to its complications, namely: cardiovascular ailments, cerebral vascular accidents, renal insufficiency, blindness, sexual impotence and gangrene of the feet leading to amputation. (who.int)
  • That's how insulin works: It stimulates capillaries to produce more NO and thus trigger vasodilation and amino acid-rich blood flow delivery to muscles. (ironmanmagazine.com)
  • Moreover, upregulated expression of the insulin receptor substrate 2 was evident in muscle biopsies of the CLA group. (medscape.com)
  • Less is known about the relationship between insulin resistance and cardiovascular risk factors in subjects with type 2 diabetes. (kaiserpermanente.org)
  • Using this definition, only 37 type 2 diabetic subjects were insulin sensitive, and the remaining 442 were insulin resistant. (kaiserpermanente.org)
  • CONCLUSIONS: We conclude that insulin-resistant type 2 diabetic subjects have more atherogenic cardiovascular risk factor profiles than insulin-sensitive type 2 diabetic subjects and that this is only partially related to increased obesity and an adverse body fat distribution. (kaiserpermanente.org)
  • A breakthrough at the Research Institute of Mount Sinai Hospital may soon get many diabetics rid of the misery of taking insulin injections twice a day, for the researchers there have developed a once-a-week jab for type 2 diabetes patients. (medindia.net)
  • Some medications are associated with insulin resistance including corticosteroids, protease inhibitors (type of HIV medication), and atypical antipsychotics. (wikipedia.org)
  • However, even in the absence of the hyperglycaemic state which characterizes type 2 diabetic patients, non diabetic individuals with a specific form of obesity, named abdominal obesity, often show clustering metabolic abnormalities which include high triglyceride levels, increased apolipoprotein B, small dense low density lipoproteins and decreased high density lipoproteins-cholesterol levels, a hyperinsulinemic-insulin resistant state, alterations in coagulation factors as well as an inflammatory profile. (researchgate.net)
  • By last year, in a small follow-up study, Shalev and colleagues had found that adult Type 1 diabetes patients taking oral verapamil required less daily insulin and showed evidence of beneficial immune modulation for as long as two years after first diagnosis. (uab.edu)
  • For many people who have Type 1 diabetes, life can become a seven-letter word: insulin. (uab.edu)
  • Individuals who develop insulin resistance are at risk of progressing to type 2 diabetes. (usda.gov)
  • Someone with insulin resistance in its early stages can develop type 2 diabetes if it continues long enough. (healthline.com)
  • Doctors may recommend diet and lifestyle modifications for people who have PCOS and a body mass index greater than 25 or a diagnosis of insulin resistance or type 2 diabetes. (medicalnewstoday.com)
  • Insulin resistance is also bad news for the onset of type 2 diabetes. (greatist.com)
  • Out of 29 liver tissue sections examined, 14 had a low level of expression of insulin receptor type 1 by immunohistochemical studies. (who.int)
  • Is cholesterol the forgotten biomarker in managing cardiovascular risk in children with type 1 diabetes? (uk.com)
  • Metabolic syndrome is a combination of conditions that include insulin resistance/Type II diabetes, HTN, hyperlipidemia, and obesity. (nursingcenter.com)
  • The primary risk factors of NASH include obesity (body mass index [BMI] >30), insulin resistance, Type II diabetes, "central adiposity" ( Paskos & Paletas, 2009 , para. (nursingcenter.com)
  • In contrast, obese individuals with a high waist circumference show excessive fat deposition in the abdomen and a pro-inflammatory state that leads to insulin resistance, which can be a precursor to Type 2 diabetes. (theconversation.com)
  • Plasma levels of mannan-binding lectin-associated serine proteases are increased in type 1 diabetes patients with insulin resistance. (bvsalud.org)
  • Carotid intimal-medial thickness was greater in insulin-resistant than in insulin-sensitive subjects, but this difference was not statistically significant. (kaiserpermanente.org)
  • The syndromes of insulin resistance actually make up a broad clinical spectrum, which includes obesity, glucose intolerance, diabetes, and the metabolic syndrome, as well as an extreme insulin-resistant state. (medscape.com)
  • T2DM has become a source total of 122 studies were considered phied, becoming more resistant to the of suffering to both patients and their for the article and were reviewed in antilipolytic effects of insulin, resulting caregivers. (who.int)
  • A mismatch between the circadian rhythm and the meals schedule, such as in circadian rhythm disorders, may increase insulin resistance. (wikipedia.org)
  • Their prevalence is higher in patients presenting cardiovascular risk factors.This review takes stock of the frequency, the mechanisms, and the implications of major cardiovascular risk factors in patients with serious mental disorders. (bvsalud.org)
  • Insulin is a hormone that facilitates the transport of glucose from blood into cells, thereby reducing blood glucose (blood sugar). (wikipedia.org)
  • More than 7 million Americans have diabetes severe enough to require daily insulin injections and frequent finger-pricks to check their blood glucose levels. (uab.edu)
  • Since the extracts did not have any significant effects on plasma insulin concentration, we speculated that they interfered with food intake and/or absorption to reduce blood glucose concentration. (endocrine-abstracts.org)
  • In patients with MetS, we found a reduction of mTOR and other mTOR-related molecules involved in insulin resistance, cell repair, coagulation and vasculogenesis. (biomedcentral.com)
  • In conclusion, the NTS rs2234762 gene variant is a determinant of reduced circulating pro-NT levels in overweight and obese children, which predisposes this group to a more favorable metabolic profile and a reduced insulin resistance later in life, independently from metabolic confounders. (lu.se)
  • Larger, longer-duration, and independently funded trials are required to confirm the potential cardiovascular benefits of cocoa flavan-3-ols. (harvard.edu)
  • 0.0001) were independently associated with lower SEVR after adjusting for age, rank, ethnicity and time from injury.ConclusionCRTI, traumatic amputation and its worsening physical deficit are associated with lower coronary flow reserve and heightened subclinical cardiovascular risk. (imperial.ac.uk)
  • To derive the greatest clinical value from the research outlined above, it is important to understand the relative role of insulin resistance in CAD compared with other well-known cardiovascular risk factors that may exist independently of insulin resistance. (diabetesjournals.org)
  • Data obtained from muscle biopsies have demonstrated altered insulin signaling (IS) in patients with MetS. (biomedcentral.com)
  • Furthermore, the precise pathophysiological characteristics underlying the association of different cardiovascular risk factors in MetS remain elusive [ 5 ]. (biomedcentral.com)
  • Therefore, IS of insulin seems to be impaired at least at the IRS-1 level in MetS. (biomedcentral.com)
  • Indeed, IS is a very complex phenomenon which is influenced not only by the cellular metabolic status but also interacts with circulating molecules such as hormones (including insulin), nutrients and inflammatory molecules. (biomedcentral.com)
  • Many hormones can induce insulin resistance including cortisol, growth hormone, and human placental lactogen. (wikipedia.org)
  • If a regular part of your diet, may affect dental health, weight gain, resistance to certain hormones, and difficulties sleeping. (hollandandbarrett.com)
  • Drinking these high-sugar drinks in excess can lead to weight gain, poor dental health, difficulties sleeping, and resistance to certain hormones. (hollandandbarrett.com)
  • Testosterone helps the body's tissues take up more blood sugar in response to insulin . (webmd.com)
  • But testosterone deficiency is connected to insulin resistance , obesity, and diabetes. (webmd.com)
  • Despite a new meta-analysis claiming to show that testosterone replacement therapy for men with hypogonadism does not increase the risk of cardiovascular outcomes such as myocardial infarction or stroke, experts say the jury is still out. (medscape.com)
  • A more definitive answer for cardiovascular safety of testosterone therapy will come from the TRAVERSE dedicated cardiovascular outcome trial , sponsored by AbbVie, which will have up to 5 years of follow-up, with results expected later this year. (medscape.com)
  • In 2014, the US Food and Drug Administration (FDA) mandated a label on testosterone products warning of possible increased cardiovascular risks and to reserve the therapy for symptomatic hypogonadism only. (medscape.com)
  • In contrast, the European Medicines Agency concluded that when hypogonadism is properly diagnosed and managed, there is currently no clear, consistent evidence that testosterone therapy causes increased cardiovascular risk . (medscape.com)
  • To address this uncertainty, Hudson and colleagues formed a global collaborative to obtain individual patient data on cardiovascular outcomes from randomized controlled trials of testosterone therapy for men with hypogonadism. (medscape.com)
  • But the insulin is less effective at removing the sugar from the bloodstream, so your blood sugar remains high. (healthline.com)
  • In clinical practice, no single laboratory test is used to diagnose insulin resistance syndrome. (medscape.com)
  • In insulin resistance, various clinical entities of this state are evident. (medscape.com)
  • Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. (mja.com.au)
  • With the arrival of human insulin, lipoatrophy, becoming a rare problem in clinical practice.Lipoatrophies are considered an adverse immunological side effect of insulin therapy, and in some cases they are mediated by a local high production of tumour necrosis factor-α, w. (endocrine-abstracts.org)
  • P = .62), nor were there any significantly increased risks of death, stroke, or different types of cardiovascular outcome, although those numbers were small. (medscape.com)
  • Insulinemia and homeostatic model assessment of insulin resistance significantly improved in the CLA group ( P = 0.045). (medscape.com)