Cardiovascular disease research models cardiovascular. Medical search. Frequent questions

Patients identified as high risk with the lifetime risk approach were more likely to be younger, male, from ethnic minority groups, and have a positive family history of premature coronary heart disease than those identified with the 10 year QRISK2 score. (bmj.com)
ICAMS research focuses on improving the prevention, diagnosis and treatment of clinical conditions and diseases such as heart failure, arrhythmias (irregular heartbeat), diabetes, ischaemic (coronary) heart disease, atherosclerosis, kidney disease, hypertension (high blood pressure), stroke and dementia. (gla.ac.uk)
Job characteristics, occupation and coronary heart disease. (cdc.gov)
In the present study we test both a new model of job -related coronary heart disease (CHD) risk, and introduce a new technique for assessing the effects of job characteristics of detailed occupational groups. (cdc.gov)
and may prevent long-term health problems, such as coronary heart disease, cancer, and stroke. (cdc.gov)
The cardiovascular risks of radiotherapy include coronary artery disease, valvular heart disease, pericardial disease, conduction system abnormalities, and myocardial fibrosis. (ajmc.com)
Management of preexisting conditions such as hypertension, coronary artery disease, congestive heart failure, heart valve disease, and arrhythmias in cancer patients requires an approach customized to their overall care. (ajmc.com)
T his kind of treatmen t is not just limited to coronary disease. (northwestern.edu)
In human subjects, studies have shown that endothelial dysfunction, recognized as impairments in flow-mediated dilation or endothelial-dependent vasodilation in response to acetylcholine, is predictive of cardiovascular events in patients with hypertension, coronary artery disease, peripheral artery disease, etc. (bu.edu)
In about 74% (411) of cardiovascular disease events the principal diagnosis was coronary heart disease. (bmj.com)
Our work involves population and family-based genetic studies, high throughput sequencing to identify disease genes, with a focus on coronary artery disease (CAD) and metabolic syndrome (MetS). (yale.edu)
The Finnish Cultural Foundation has awarded significant grants to 6 projects studying, among other things, coronary artery disease and heart insufficiency. (skr.fi)
The most common cardiovascular diseases are coronary artery disease, heart insufficiency, and cerebrovascular disease. (skr.fi)
Professor Juhani Knuuti and the KOVERI research project (Turku PET Centre) received €264,500 for research on imaging changes in other organs related to coronary artery disease. (skr.fi)
The research is producing unique information on the interaction between the heart and other organs and on the changes caused by coronary artery disease in the blood circulation of other organs. (skr.fi)
Professor Seppo Ylä-Herttuala and a research group at the University of Eastern Finland's Faculty of Health Sciences received €200,000 for research on developing gene therapy for improving the treatment of heart failure and the treatment of ischemia-reperfusion injury caused when opening up blocked coronary arteries. (skr.fi)

The Wu Laboratory seeks to identify mechanisms responsible for human heart diseases, the most common cause of death in the U.S. and the biggest contributor to morbidity and mortality worldwide. (stanford.edu)
Cardiovascular diseases cause a high mortality rate worldwide and represent a major burden for health care systems. (springer.com)
The relationship between increased short-term mortality rates after invasive pneumococcal disease (IPD) has been frequently studied. (cdc.gov)
However, studies on long-term mortality rates after IPD have been largely deficient, despite IPD being a reportable disease in Canada since 2000 ( 9 ). (cdc.gov)
In this study, the researchers examined the association between obesity and mortality among people with cardiovascular disease, comparing incident and prevalent disease cases in the same dataset. (nyu.edu)
7 The interplay and balance between the competing morbidity and mortality of cardiovascular disease and cancer is particularly important in an older population, whose risks are inherently higher. (ajmc.com)
The revised agricultural policy may be an opportunity to improve population health by supporting domestic production and consumption of fruits and vegetables (F&V). This study aims to quantify the potential impacts of a post-Brexit agricultural policy that increases land allocated to F&V on cardiovascular disease (CVD) mortality and inequalities in England, between 2021 to 2030. (bmj.com)
The model combined data on F&V agriculture, waste, purchases and intake, CVD mortality projections and appropriate relative risks. (bmj.com)
Conclusion Post-Brexit agricultural policy presents an important opportunity to improve dietary intake and associated cardiovascular mortality by supporting domestic production of F&V as part of a comprehensive strategy that intervenes across the supply chain. (bmj.com)
Antenatal glucocorticoids accelerate fetal lung maturation and reduce mortality in preterm babies but can trigger adverse effects on the cardiovascular system. (researchgate.net)
Chronic progressive cardiovascular (CV) disease, in all its clinical manifestations, is the most significant cause of morbidity and mortality in many developed countries and, increasingly, in countries experiencing economic growth and prosperity. (nih.gov)
Cholesterol has a bad reputation, associated with cardiovascular disease, the leading worldwide cause of morbidity and mortality. (nih.gov)
Despite decreases in mortality rates due estimate of myocardial infarction inci- of the population census from the Sta- to cardiovascular diseases in most de- dence has been reported for the whole tistical Center of Iran in 2011 were used. (who.int)
In view of To adjust the rates, we used the direct become the most important health this, and reports of the varying distri- standardization method and the WHO problem and cause of mortality in bution of cardiovascular disease risk standard population ( 18 ). (who.int)

Our mission is to improve the lives of children with heart disease through patient centered research with demonstrable clinical outcomes. (ucl.ac.uk)
Research is the core of the institute, around which all other activities - including teaching, training, clinical care and public outreach - take place. (gla.ac.uk)
It is an outstanding research environment, with more than with more than 55 principal investigators conducting basic, translational and clinical research. (gla.ac.uk)
The core facilities include clinical trials, vascular phenotyping in humans, and vascular functional studies in humans and experimental models. (gla.ac.uk)
His research overlaps with these clinical areas but also covers broad aspects of medicine and innovation. (biomedcentral.com)
His experience includes 24 years of clinical practice, 19 years of translational research in nanomedicine, and 13 years of bench-to-bedside studies, including imaging, vascular pathology, and medical devices (bioresorbable scaffolds and stents). (biomedcentral.com)
Researchers from France are developing a model to find biomarkers and clinical risk factors that can better identify individuals at risk for cancer who should be screened. (medscape.com)
Using machine learning, the team highlighted more than 30 biomarkers and 2 clinical risk factors among patients with cardiovascular disease who smoked and 13 biomarkers and 8 clinical risk factors among patients with Li-Fraumeni syndrome that could effectively identify those at risk for cancer. (medscape.com)
Using machine learning, the researchers found 33 biomarkers and 2 clinical risk factors among patients with cardiovascular disease that led to a cancer risk estimate with an area under the curve (AUC) of 0.78. (medscape.com)
W e 're hoping that our studies (with iron chelators and cardiovascular disease) in the preclinical phase , will guide us to translate those into clinical practice and treating patients with various chronic diseases. (northwestern.edu)
His work is currently in animal models, but he hopes to bring it into human clinical trials to investigate iron chelator therapies for many chronic diseases, including cancer. (northwestern.edu)
As a physician scientist, Ardehali values the ability to relate his clinical practice to his research and vice versa. (northwestern.edu)
When studying the cardiovascular system before birth, the temporal profile of cardiovascular development between species is a highly important consideration for translation to the human clinical situatio. (researchgate.net)
Most research coming from the Global Public Health team is based on population-based epidemiological studies, analysis of register data, surveillance and modelling based on the epidemiological data, clinical and molecular epidemiology studies, health promotion studies, health system research, and development studies. (gu.se)
Our customers have come to expect full service from us including product technical support and clinical education, research and science resources, and practice development support and solutions, but don't take it from us- read testimonials from some of our loyal customers. (bioticsresearch.com)
Any practice looking to incorporate the finest nutritional supplements should seriously consider Biotics Research…unsurpassed quality and clinical efficacy! (bioticsresearch.com)
Whether adequate levels of vitamin D improve nonskeletal cardiovascular or cognitive benefits remains the subject of debate, and answers await randomized clinical trial data. (sciencedaily.com)
Chris' primary research focus is on using experimental and clinical data to predict how heart cells, the engine of every heartbeat, respond to genetic mutations and to drugs. (swansea.ac.uk)
This programs consists of seven interdisciplinary doctoral programs with over 200 participating research faculty from 32 basic science and clinical departments. (unmc.edu)
This ARC is intended to promote translational research by bringing basic and clinical research laboratories together to study the cardiovascular consequences of obesity and diabetes. (bu.edu)
This ARC will coordinate activities of basic science labs and clinical research labs to assess the interrelationship between metabolic dysfunction and vascular disease. (bu.edu)
The funds from this ARC will be used to 1) initiate collaborative studies in mouse models on mechanisms of obesity-linked cardiovascular diseases and 2) support research where basic science and clinical research labs perform molecular analyses on tissues and cell samples isolated from patient populations. (bu.edu)
Demographic, clinical and imaging characteristics are used to risk-stratify patients, and nomograms exist that combine these characteristics into composite models to classify tumors preoperatively. (ahrq.gov)
Surveys were linked prospectively to clinical hospital records, and Cox proportional hazards models were used to estimate the risk of cardiovascular disease events or death according to oral hygiene. (bmj.com)
Previous smaller epidemiological studies that have examined the association between oral health and cardiovascular disease have generally used clinical assessments to identify periodontal disease. (bmj.com)
She completed a post-doctoral fellowship at the Clinical Research Institute of Montreal (CRIM) in 1996 and then progressed the scientific/academic ladder to become Staff Scientist and Professor in the CRIM. (mcgill.ca)
In addition to her clinical and scientific activities, she is an inspirational leader and passionate mentor and teacher and has trained over 100 PhD and MD students and fellows, in basic, translational and clinical research. (mcgill.ca)
Evidence-based life-course causal models will estimate how clinical and policy interventions may sustainably affect the health and economic burden of NCDs. (europa.eu)
It's been a rewarding progression in my career, going from studying single cells in culture to animal models to translational and clinical studies. (asbmb.org)
How do you apply an insight from a large clinical trial to a mouse model? (asbmb.org)
We have developed expertise in in vivo investigation of lipid and glucose metabolism, insulin secretion and sensitivity, and vascular biology and in human physiological studies, leading to discovery of attractive drug targets that have been either patented or being investigated for their utility in treatment of fatty liver disease and diabetes in 2 clinical trials in the outlier populations of Fars/Iran. (yale.edu)
He leads CAMP MGH (Cardiovascular and Metabolic Patient Cohort), a large clinical cohort that draws subjects from MGH Heart Center patients. (massgeneral.org)
Dr. Huang's clinical interests are in cardiovascular disease prevention with a particular interest in links between diabetes and heart disease. (massgeneral.org)
The Lipoprotein Metabolism Laboratory, led by Dr. Alan T. Remaley, seeks to better understand lipoprotein metabolism and to translate new insights gained from basic biochemistry, cell biology, and transgenic animal models into much-needed clinical advances in the treatment and prevention of cardiovascular disease. (nih.gov)

Li et al, Development 2019) as well as the developing cardiac conduction system at embryonic day 16.5 of mouse development (Goodyer et al, Circulation Research 2019). (stanford.edu)
A new proteomic risk model for cardiovascular disease was found to be more accurate than current methods of measuring cardiac risk, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. (news-medical.net)
Not only did the study indicate this model was more accurate compared to current approaches, the researchers were able to identify several proteins, like cartilage intermediate layer protein 2 (CILP2), that can be used in future research to identify cardiac risk or be the target for novel therapies. (news-medical.net)
In this review, we summarize the current advances of the IMPC in cardiac research and describe in detail the diagnostic requirements of high-throughput electrocardiography and transthoracic echocardiography capable of detecting cardiac arrhythmias and cardiomyopathies in mice. (springer.com)
In 2005, he founded the MGH Cardiac Metabolic Syndrome Program in the Cardiovascular Disease Prevention Center. (massgeneral.org)

11, 2022 Metabolic syndrome increases a person's risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar. (sciencedaily.com)
Jan. 11, 2022 Women who breastfed at some time in their lives were less likely to develop heart disease or stroke, compared to women who did not breastfeed, according to a meta-analysis of previous studies. (sciencedaily.com)
2022 May 1, In: Journal of Lipid Research. (lu.se)

Researchers in Glasgow have significantly advanced the field of cardiovascular biology and medicine in areas like heart failure, stroke, biomarkers and hypertension. (gla.ac.uk)

Chronic kidney disease (CKD) is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. (news-medical.net)
A new study suggests that this same combination could help prevent metabolic syndrome, a constellation of conditions that increases the risk of heart disease, stroke, and diabetes in postmenopausal women. (sciencedaily.com)
1 Cardiovascular Health and Diabetes Section, Montana Department of Public Health and Human Services, Helena, MT 59620-2951, USA. (nih.gov)
Obesity and its comorbidities, including hypertension, hyperlipidemia and type 2 diabetes mellitus, have a devastating impact on vascular function leading to conditions that promote cardiovascular disease. (bu.edu)
Environmental factors, including air and noise pollution, and the built environment, are typically associated with cardiovascular and metabolic non-communicable diseases (NCDs), e.g. obesity, type 2 diabetes, heart diseases and atherosclerosis. (europa.eu)
As it happens, Bornfeldt became interested as a graduate student in how diabetes predisposes patients to heart disease. (asbmb.org)
She continues to probe the links between the two diseases as the deputy director of, and director of the diabetes complications research program at, the University of Washington's Diabetes Institute. (asbmb.org)
Before my graduate studies, I had not heard of women having heart attacks in their 30s, and it made me realize that the connection between diabetes and early heart disease was something that we urgently needed to understand and find treatments for. (asbmb.org)
At that time there weren't any good animal models to study diabetes-accelerated atherosclerosis, the process that leads to cardiovascular disease. (asbmb.org)
As a graduate student, I learned a lot about diabetes, and I decided to pursue studies in atherosclerosis by moving to the University of Washington to train with Russell Ross , who was a leader in atherosclerosis research. (asbmb.org)
After my postdoc period, I set up my own lab here at the University of Washington, and that's when I had the opportunity to really focus on cardiovascular complications of diabetes by generating a mouse model of that disease. (asbmb.org)
we generated a new mouse model that we still use a lot to study mechanisms whereby diabetes promotes atherosclerosis. (asbmb.org)
We're now basing our research on data from human studies to be sure that we're studying the most important drivers of cardiovascular disease risk in diabetes in humans. (asbmb.org)
We are now fully characterizing this protein and evaluating its utility as a drug target for diabetes, dyslipidemia, and fatty liver disease. (yale.edu)
the simvastatin intervention rats had a higher FPG compared to the diabetic rats and were more easily be induced to diabetes at the end of 4 weeks, FPG level of simvastatin treatment rats was increased compared with diabetic model rats after 12 weeks. (hindawi.com)
Type 2 diabetes mellitus is ordinarily associated with dyslipidemia, which presents a synergistic risk factor for cardiovascular disease [ 1 ]. (hindawi.com)
Scientists at the Ottawa Hospital Research Institute and the University of Ottawa have discovered what may be an important clue to the cause of type 1 diabetes. (sciencedaily.com)
Type 1 diabetes is an autoimmune disease that occurs when the immune system mistakenly attacks the pancreas, the organ that regulates blood sugar. (sciencedaily.com)
Dr. Scott's research is the first to clearly show that immune cells called T cells from people with type 1 diabetes are also more likely to over-react to wheat. (sciencedaily.com)
His research also shows that the over-reaction is linked to genes associated with type 1 diabetes. (sciencedaily.com)
Our research suggests that people with certain genes may be more likely to develop an over-reaction to wheat and possibly other foods in the gut and this may tip the balance with the immune system and make the body more likely to develop other immune problems, such as type 1 diabetes. (sciencedaily.com)
In a commentary accompanying the paper, diabetes expert Dr. Mikael Knip of Finland said "These observations add to the accumulating concept that the gut is an active player in the diabetes disease process. (sciencedaily.com)
Dr. Scott's previous research has shown that a wheat-free diet can reduce the risk of developing diabetes in animal models, but he notes that more research will be required to confirm the link and determine possible effects of diet changes in humans. (sciencedaily.com)
This research was funded by the Juvenile Diabetes Research Foundation and the Canadian Institutes of Health Research. (sciencedaily.com)
8, 2019 People under age 40 diagnosed with type 2 diabetes are more likely to have or die from cardiovascular disease than people of a similar age who do not have type 2 diabetes. (sciencedaily.com)
Internationally known as a leader in the area of nitric oxide (NO) biology, Dr. Huang's research investigates the molecular mechanisms linking diabetes, obesity and hyperlipidemia to cardiovascular and cerebrovascular disease. (massgeneral.org)
Diabetes kan ännu idag inte botas och den dramatiska ökningen av diabetes är en tickande bomb, därför är det särskilt angelägen att hitta nya strategier för att begränsa diabetes relaterade skador. (lu.se)

The BHF Centre of Research Excellence, which focuses on vascular biology and biomedicine, opened in April 2014 and was awarded an initial £3M research grant to help the UK's brightest young doctors and scientists find new and innovative ways to fight cardiovascular disease and its complications. (gla.ac.uk)
Working closely with the cancer care team, we provide a comprehensive cardiovascular evaluation and treatment plan prior to cancer therapy to minimize cardiovascular complications. (ajmc.com)
However, glucocorticoid treatment in the infant can increase the risk of long-term cardiovascular complications including. (researchgate.net)

These extensive high-throughput data from IMPC mice provide a promising opportunity to explore genetics causing metabolic heart disease with an important translational approach. (springer.com)
Hossein Ardehali, MD, PhD, is working to understand the role of iron and metabolic processes in cardiovascular disease and develop new therapies that target iron accumulation in people with CVD and many other chronic diseases. (northwestern.edu)
Today's guest, Dr. Hossein Ardehali, is focused on the role of metabolic processes and cardiovascular disease. (northwestern.edu)
The progression of abdominal obesity and heart disease that lead to metabolic syndrome increases significantly as women age and appears to be directly associated with estrogen loss in postmenopausal women. (sciencedaily.com)
We propose projects to define the molecular mechanisms by which metabolic disease impacts vascular function and vice versa . (bu.edu)
The ARC takes a well integrated approach to understand the functional interrelationships between metabolic disease and vascular dysfunction. (bu.edu)
We leverage modern techniques of functional genomics, epigenetics, transcriptomics, proteomics, gene editing and model-driven experimentation to understand the underlying causes of atherosclerosis and metabolic syndrome and discover therapeutic targets. (yale.edu)
By recruiting more than thousand kindreds with early onset CAD and multiple metabolic risk factors for genetics and metabolic studies we have been able to map, identify and characterize a dozen of human disease genes for CAD and MetS, which have been reported in leading journals such as Nat Genet, Science, NEJM, Cell Metab, JCI, PNAS, AJHG, etc. (yale.edu)
One of our groundbreaking discoveries was the identification of founder mutations in the DYRK1B gene, underlying atherosclerosis, metabolic syndrome, and fatty liver disease. (yale.edu)

The BHF Centre of Research Excellence brings together outstanding researchers across multiple disciplines at the University of Glasgow and worldwide, studying the whole spectrum from the biology of heart and vascular cells and how they interact, to how and why the heart and blood vessels become inflamed and injured and how this contributes to the development of cardiovascular diseases. (gla.ac.uk)
Adjunct professor Katariina Öörni and a research group at the Wihuri Research Institute received €180,000 for research on the reasons for the qualitative characteristics of lipoproteins and research on their effects on the development of cardiovascular diseases. (skr.fi)

We believe that by understanding the mechanisms regulating the formation of the heart during fetal development we can then apply these principles to understand the causes of adult heart diseases such as heart attack and heart failure. (stanford.edu)
The University of Glasgow's Institute of Cardiovascular & Medical Sciences (ICAMS) is working to tackle this global problem by exploring the causes and mechanisms of cardiovascular disease. (gla.ac.uk)
This comprehensive platform allows the examination of arteries at many levels that can inform us about mechanisms and causes of vascular disease and new approaches to promote vascular health. (gla.ac.uk)
However, the underlying molecular mechanisms of medicinal herbs in treating these diseases are still unclear. (nih.gov)
Importantly, oral dysbiosis promotes cardiovascular pathophysiology through different mechanisms. (degruyter.com)
Some common mechanisms by which oral dysbiosis increases cardiovascular risks have been illustrated in Figure 1 . (degruyter.com)
Liver diseases are considered the risk factors for CVDs, where liver disease patients are more susceptible to endothelial dysfunction and arterial calcification, although the detailed mechanisms underlying the causality between liver diseases and CVDs require further study [ 5 ]. (degruyter.com)
Common mechanisms of oral dysbiosis-promoted cardiovascular pathophysiology. (degruyter.com)
To achieve this, we conduct research on the biological and social determinants of health to understand the mechanisms of illnesses. (gu.se)
I thought better animal models would be needed in order to understand mechanisms and move the research area forward. (asbmb.org)
Research in these departments is mainly focused on different aspects of mechanisms of inflammation and cardiovascular pharmacology, with many projects overlapping these two areas. (bioethics.ac.uk)

Due in large part to the increased prevalence of cardiovascular disease, it is estimated that life expectancy declines by 3 years for those with a Body Mass Index (BMI) over 30 and 10 years for those with a BMI over 40. (bu.edu)

It has the potential to revolutionise healthcare and treatment of chronic diseases such as cardiovascular disease. (gla.ac.uk)
We are hoping that if we see positive results, we will extend it to other chronic diseases, including neurological diseases and maybe other chronic diseases like cancer. (northwestern.edu)
A major goal of his research is to find ways to reduce iron in chronic diseases and therefore reduce the oxidative stress that iron can cause. (northwestern.edu)
He has long been fascinated with the role of iron in chronic diseases such CVD. (northwestern.edu)
The influence of social and behavioral factors in the workplace, or more accurately the composite elements of working life on cardio-vascular and other chronic diseases, has influenced several major currents in occupational health research. (cdc.gov)
Furthermore, these large LHDs have adjusted to the epidemiological transition from communicable to chronic disease and developed a wide array of primary prevention programs for chronic diseases (6). (cdc.gov)

Mice with pulmonary arterial hypertension had very high levels of Nogo in their lung arteries, but animal models that were genetically lacking Nogo were completely resistant to developing the disease," said Michelakis. (wun.ac.uk)
In addition to work done in laboratory models, the research team found that the level of Nogo was also high in arteries of patients with pulmonary arterial hypertension. (wun.ac.uk)
Michelakis took samples from 41 patients at his pulmonary hypertension clinic and compared it to 26 patients who didn't have the disease. (wun.ac.uk)
We believe that by bringing along these [spinal cord and neurology] colleagues into the field of pulmonary hypertension, we'll contribute to accelerating knowledge and discovery of new therapies in this disease," said Michelakis. (wun.ac.uk)
In 2005 she was recruited to the Kidney Research Centre, Ottawa Hospital Research Institute, Univeristy of Ottawa, where she was the Canada Research Chair in Hypertension Tier 1, until 2011 when she was recruited to the University of Glasgow to direct ICAMS. (mcgill.ca)
She has played major leadership roles in the premier national and international hypertension and cardiovascular organisations. (mcgill.ca)
She was President of the Canadian Hypertension Society (2007-2008), Chair of the High Blood Pressure Research Council (AHA) (2010-2012), President of the International Society of Hypertension (2014-2016) and President of the European Council for Cardiovascular Research (2019-2021). (mcgill.ca)
She was the founder and Chair of the 'Women in Hypertension Research Network' of the International Society of Hypertension, the mission of which is to encourage, support and inspire women in science and medicine in the field of hypertension and related cardiovascular diseases and to facilitate new avenues for communication, collaboration and education. (mcgill.ca)

The study aimed to explore the experiences of people with cardiovascular disease in patient education. (biomedcentral.com)

IMPORTANCE: The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC). (healthpartners.com)

Background: Electronic health (eHealth) is a multidisciplinary and rapidly evolving field, and thus requires research focused on knowledge accumulation, curation, and translation. (utwente.nl)
Cardiovascular diseases constitute a global health care crisis in which eHealth can provide novel solutions to improve the efficiency and reach of self-management support for patients where they most need it: their homes and communities. (utwente.nl)
Access to anonymised patient data from the National Health Service (NHS) in Scotland means ICAMS researchers are advancing disease-specific bio resources, helping to identify and develop targeted treatments for particular groups of patients. (gla.ac.uk)
ICAMS clinicians work directly with patients in NHS hospitals within the Greater Glasgow & Clyde Health Board and in the Golden Jubilee National Hospital, which is home to Scotland's National Services in Adult Congenital Heart Disease, Advanced Heart Failure and Pulmonary Vascular Disease. (gla.ac.uk)
His scientific background includes pharmaco-epidemiology and big data research within nationwide Danish Health databases. (biomedcentral.com)
Cardiovascular disease (CVD) is a world-leading health problem and encompasses a broad spectrum of disorders, including diseases of the blood vessels, the heart muscle, the electrical conduction system, and congenital heart disease. (springer.com)
However, with an aging population at risk for IPD, and pneumococcal serotypes changing to evade current vaccinations, IPD remains a disease of public health concern ( 12 ). (cdc.gov)
However, a new study by NYU College of Global Public Health and the University of Michigan finds that this 'obesity paradox' is not present among people with new cases of cardiovascular disease. (nyu.edu)
Because dietary factors 'contribute substantially to the burden of preventable illness and premature death in the United States,' the national health promotion and disease prevention objectives encourage schools to provide nutrition education from preschool through 12th grade (1). (cdc.gov)
These guidelines are based on a synthesis of research, theory, and current practice and are consistent with the principles of the national health education standards (29), the opportunity-to-learn standards for health education (29), the position papers of leading voluntary organizations involved in child nutrition (30), and the national action plan to improve the American diet (31). (cdc.gov)
Oral dysbiosis refers to the imbalance between symbionts and pathobionts in the oral cavity, posing potential threats to host cardiovascular health. (degruyter.com)
With the prognosis for many cancers improving, we are seeing an appropriate sharpening of focus on the cardiovascular risks of patients who have survived cancer or are being treated for cancer, as well as a growing recognition of the impact this competing morbidity has on both short- and long-term health outcomes. (ajmc.com)
The concept of the early life developmental origins of health and disease (DOHaD) in adults has stimulated a new approach to understanding disease trajectories, with major public health implications. (researchgate.net)
Indeed, the principle of the 'lifecourse of disease' now influences health policies internationally. (researchgate.net)
Global public health is an interdisciplinary subject that transcend national boundaries as area for education, research, and practice that places a priority on improving health and achieving health equity for all people worldwide. (gu.se)
The research in the Global Public Health group is driven by a multidisciplinary team with 33 members (and growing), led by four professors, four associate professors, senior lectures, post-docs, researchers, as well as 14 PhD students. (gu.se)
The research conducted in the Global Public Health group aims to reduce health inequalities and improve the population health at worldwide. (gu.se)
This knowledge will allow us to identify health promotion strategies that could promote health and prevent diseases. (gu.se)
The research group has an interest to develop more research within the field of climate change and health in the near future. (gu.se)
Biotics Research has proven to be an integral partner in my practice, contributing to practice revenues and patient health. (bioticsresearch.com)
Health services research and value-based care that addresses disaster-related injury and illness for chronic disease. (cdc.gov)
NOTE: Health services research examines how people get access to health care, how much care costs, and what happens to patients as a result of this care. (cdc.gov)
The Research-to-Care Logic Model is used by the WTC Health Program to evaluate the effectiveness of the WTC research program. (cdc.gov)
His research is funded by the British Heart Foundation, BBSRC, Wellcome Trust, MRC, Health and Care Research Wales and the European Union. (swansea.ac.uk)
If you are giving a presentation about an environmental health topic or just looking for general information about environmental health research or the institute, this page will help. (nih.gov)
NIEHS is committed to conducting the most rigorous research in environmental health sciences, and to communicating the results of this research to the public. (nih.gov)
NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
NIEHS offers a broad range of job opportunities, career enhancement programs, and research training grants and programs in environmental health sciences and administration. (nih.gov)
The Rotterdam study also used other methodology to assess lifestyle and/or health measures including the European cardiovascular disease risk assessment model. (cdc.gov)
Endothelial cell function has long been viewed as a barometer of overall cardiovascular health. (bu.edu)
4 5 6 7 Systemic inflammation could represent the underlying mechanism that links oral health and cardiovascular disease. (bmj.com)
Executive Director and Chief Scientific Officer of the Research Institute of the McGill University Health Centre, Dr. Phil Gold Chair in Medicine and Professor in Family Medicine, McGill University, Montreal, Canada. (mcgill.ca)
Dr Touyz, is the Executive Director and Chief Scientific Officer of the Research Institute of the McGill University Health Centre. (mcgill.ca)
the Wellcome Trust Physiology in Health and Disease, UK and Imperial College BHF Centre of Research Excellence, London UK. (mcgill.ca)
Despite this, research has not focused enough on the life-course characterisation of the exposome and the application of this to health and disease. (europa.eu)
Most of the health problems of older age are linked to chronic conditions, particularly noncommunicable diseases. (who.int)
Why is cardiovascular disease a problematic issue for many occupational safety and health investigators? (cdc.gov)
This is a central issue for workplace health promotion (WHP) and occupational disease prevention. (cdc.gov)
The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), Public Health Service, U.S. Depart- ment of Health and Human Services, Atlanta, GA 30333. (cdc.gov)

Animal models have many facets that mimic various disease conditions in humans representing the importance for its tremendous use in biomedical research (Mukherjee et al. (springer.com)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
The MGH Cardio-Oncology Program introduced in 2011 is a joint initiative between the Heart and Cancer Centers at Massachusetts General Hospital that provides comprehensive cardiovascular care to cancer patients, with the goal of improving short- and long-term outcomes ( Figure ). (ajmc.com)

Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)
9 10 11 12 Lifetime risks which measure the cumulative risk of developing a disease during the remainder of an individual's life 13 would reflect this relatively high risk and, given that lifetime risk estimates provide assessment over the full life course, they may provide a more appropriate assessment of future risks than estimates limited to 10 years, particularly at younger ages. (bmj.com)
DESIGN, SETTING, AND PARTICIPANTS: Microsimulation modeling was used to estimate long-term benefits and harms for hypothetical US cohorts of men and women aged 40 to 79 years with up to 20% 10-year risk for an atherosclerotic CVD event and without prior history of CVD or elevated bleeding risks. (healthpartners.com)
Oral dysbiosis, which potentially causes periodontitis to subsequently promote systemic inflammation and local vascular inflammation, increases the risks of cardiovascular diseases (CVDs). (degruyter.com)
Altogether, the altered immune and inflammatory responses, and endotoxemia contribute to the dysfunction and stress in cardiovascular cells (e.g . endothelial cells, vascular smooth muscle cells and cardiomyocytes), increasing cardiovascular risks. (degruyter.com)
For many patients, determining if there are cardiovascular risks that need to be addressed before they undergo medical or surgical treatments for cancer is necessary in order to ensure optimal outcomes. (ajmc.com)
This multidisciplinary program helps participants reduce their risks for heart disease by focusing on nutrition, physical activities and mindset toward healthy behavior over the long term. (massgeneral.org)
thus, treatment of ED in these patients must take cardiovascular risks into account. (medscape.com)

Furthermore, we are presenting not yet associated loss-of-function genes affecting both, metabolism and the cardiovascular system, such as the RING finger protein 10 ( Rfn10 ), F-box protein 38 ( Fbxo38 ), and Dipeptidyl peptidase 8 ( Dpp8 ). (springer.com)
Dr. Paul Huang's research focuses on the roles of nitric oxide (NO) in cardiovascular disease and metabolism, using techniques ranging from molecular biology, physiology, and genetically altered mouse models, to human translational studies and induced pluripotent stem (iPS) cell approaches. (massgeneral.org)
The exposure to patients with rare diseases often leads to new insights into common disease processes that can be obtained in no other manner and inspires him and his co-workers to translate their basic science findings in cholesterol metabolism into new therapies for cardiovascular disease. (nih.gov)

This new model was found to be more accurate in identifying those at risk of future cardiovascular disease, as compared to both the 2013 ACC/AHA Pooled Cohort Equation (PCE)-;which provides a set of guidelines for best practices in measuring cardiovascular risk-;and a modified PCE that included estimated glomerular filtrate rate (eGFR). (news-medical.net)

Obesity promotes a chronic inflammatory state, which contributes to the development of insulin resistance and cardiovascular disease. (bu.edu)

Hence, with this call for papers, BMC Cardiovascular Disorders acknowledges that new approaches are fundamental to the advancement of modern cardiology. (biomedcentral.com)
Please ensure your manuscript adheres to the submission guidelines for BMC Cardiovascular Disorders . (biomedcentral.com)
Cardiovascular disease (CVD) refers to a group of cardiovascular disorders and is currently the first leading cause of death worldwide. (biomedcentral.com)

Our understanding of fetal cardiovascular physiology has markedly increased in the last 50 years, with the introduction of suitable animal models. (researchgate.net)
He is also a member of the editorial board of Cardiovascular Research, Frontiers in Physiology and Artery Research. (swansea.ac.uk)
She was drawn to medical research - although she might happily have studied ethology, plant physiology or other fields of biology. (asbmb.org)

Although obesity is a well-known risk factor for getting cardiovascular disease, a controversial body of research suggests that obesity may actually be associated with improved survival among people who have cardiovascular disease. (nyu.edu)
Among those with prevalent disease, the researchers observed a strong and significant obesity paradox, replicating earlier findings. (nyu.edu)
iii) cardiovascular oncology, and iv) cardiometabolic disease, obesity and adipose biology. (mcgill.ca)

BACKGROUND: Epidemiological studies have linked transportation noise and cardiovascular diseases, however, atrial fibrillation (AF) has received limited attention. (lu.se)

The Laboratory for Biomechanics, Biolab, hosts a variety of equipment and experimental setups to facilitate the ongoing research in the field of cardiovascular and orthopaedic biomechanics of the department of Biomedical Engineering. (tue.nl)

The researchers focused on specific cardiovascular disease diagnoses: myocardial infarction (heart attack), chronic heart failure, stroke, and ischemic heart disease. (nyu.edu)
These subjects didn't have any cardiovascular disease when the plasma samples were collected, but they were followed over time so that we knew who developed a myocardial infarction later on. (asbmb.org)
The t -test were previously of greatest concern to of myocardial infarction at the national and analysis of variance were employed high-income countries ( 3 ), the age- and provincial level in the Islamic Re- to compare differences in means of con- adjusted incidence of these diseases public of Iran. (who.int)

Those specific proteins were determined to best help indicate a patient's risk level of heart attack, heart failure, stroke, or even cardiovascular death in those with CKD. (news-medical.net)
This complex binds proteins to determine the fate of neurons, and we are studying the function of its various components in models of stroke, vascular dementia and ageing. (edu.au)
Cardiovascular disease (CVD) is the number one cause of death globally, and nearly half of all U.S. adults are currently at risk for heart attack and stroke. (northwestern.edu)
Because CPH-NEW is sponsoring a cardiovascular disease and stroke education and outreach population and is undertaking an intervention among Corrections Officers, a group with many stress related concerns, the issues around workplace interventions and CVD are cogent. (cdc.gov)

Experimental rodent models play a central role in cardiovascular disease research by effectively simulating human cardiovascular diseases. (springer.com)
we're combining data that we get from large human cardiovascular outcome studies with the mechanistic mouse models that we have in the lab. (asbmb.org)

We also use human stem cells as a test-tube model to study the process of heart formation and to create new human heart tissues and organs from these stem cells. (stanford.edu)
The Penn researchers developed a model using proteomics, the large scale study of proteins. (news-medical.net)
All participants had CKD and no history of cardiovascular disease at study baseline. (news-medical.net)
We welcome the submission of research papers (including methods), study protocols, technical advancements, systematic reviews, and meta-analyses. (biomedcentral.com)
This qualitative study involved 30 adult patients with cardiovascular disease who were hospitalized or had a history of hospitalization. (biomedcentral.com)
This study provides valuable information about the problems of patient education for adults with cardiovascular disease. (biomedcentral.com)
In the study, Fidelle and colleagues first analyzed data in approximately 500 patients from the PREVALUNG trial , which included current or former smokers with cardiovascular disease who were part of a lung cancer screening program. (medscape.com)
The study received funding from the European Union's Horizon Europe research and innovation program. (medscape.com)
When ZEISS Lattice Lightsheet 7 was presented to the research community in 2020, it marked a milestone in the development of microscopy techniques for the study of life. (zeiss.com)
Conclusion Our study showed that an online chat-based AI model has a broad knowledge of CVD racial disparities, however persistent gaps in knowledge about minority groups. (medrxiv.org)
This smaller, but population representative study in Rotterdam examined a similar research question. (cdc.gov)
The UK Biobank study defined development of dementia disease through linkage to healthcare records, while the more recently published Rotterdam study used research-grade diagnoses for this purpose. (cdc.gov)
The study provides baseline data for monitoring and managing cardiovascular diseases in the country. (who.int)

Ideally, these drugs would target only cancer cells, but the potential for cardiovascular effects exists due to the presence of identical molecular pathways in cardiovascular cells. (ajmc.com)
Subsequent molecular and physiological studies in human mutation carriers and animal models have allowed us to unravel novel functions of the identified genes, to delineate their cognate pathways and to discover new targets for pharmaceutical intervention. (yale.edu)

She was recruited to Montreal in September 2021 after serving 10 years as the Director of the Institute of Cardiovascular & Medical Sciences (ICAMS) and British Heart Foundation Chair and Professor of Cardiovascular Medicine, University of Glasgow, United Kingdom. (mcgill.ca)

Iron accumulation can affect older people through atherosclerosis that can lead to vascular disease and neurological disease such as Alzheimer's and Parkinson's. (northwestern.edu)
1 Inflammation plays an important role in the pathogenesis of atherosclerosis, and markers of low grade inflammation have been consistently associated with a higher risk of cardiovascular disease. (bmj.com)
His laboratory has developed small synthetic peptide mimetics of apoA-I, and like the full-length protein, these peptides mobilize excess cholesterol from cells and have been shown to reduce atherosclerosis and inflammation in animal models. (nih.gov)

Dysbiosis of both oral and gut microbiomes result in systemic inflammation and endotoxemia to cause liver dysfunction and even liver diseases (e.g . cirrhosis, nonalcoholic fatty liver disease and nonalcoholic steatohepatitis) [ 4 ]. (degruyter.com)
Objective To examine if self reported toothbrushing behaviour is associated with cardiovascular disease and markers of inflammation (C reactive protein) and coagulation (fibrinogen). (bmj.com)
Conclusions Poor oral hygiene is associated with higher levels of risk of cardiovascular disease and low grade inflammation, though the causal nature of the association is yet to be determined. (bmj.com)
2 Consequently, contributing factors associated with inflammation and chronic infections, including oral infections such as periodontal disease, have been investigated to explain the relation between dental disease and cardiovascular disease. (bmj.com)

The aim of this research is to optimize and individualize cancer screening and improve cancer prediction, detection, and prevention, according to Marine Fidelle, PharmD, PhD, research pharmacist at the Gustave Roussy Institute, Paris, who presented the findings at the Society for Immunotherapy of Cancer's (SITC) annual meeting in San Diego. (medscape.com)

8 C reactive protein and fibrinogen are sensitive markers used to evaluate the inflammatory status of an individual, and the results of prospective longitudinal studies indicate that these markers might be useful predictors for future cardiovascular events in various populations. (bmj.com)

2023). Proteomic cardiovascular risk assessment in chronic kidney disease. (news-medical.net)
Cite this: Model Helps Optimize Who Should Be Screened for Cancer - Medscape - Nov 08, 2023. (medscape.com)

Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
Aims We aim to estimate the cost and cost-effectiveness of population-based tobacco control strategies in the prevention of cardiovascular diseases (CVD) in Tanzania. (who.int)
Multilevel structural equation modeling was used to estimate the hypothesized relationships at the individual and work-unit levels. (bvsalud.org)

Our division seeks to understand how pathological aging and neurodegenerative diseases (Vascular Dementia) differ from normal aging. (edu.au)
Vascular dementia (VaD) is the second leading cause of dementia after Alzheimer's disease. (edu.au)

Since 2019, she also has served as an associate editor of the Journal of Lipid Research. (asbmb.org)

ICAMS is home to a British Heart Foundation (BHF) Centre of Research Excellence, one of only six in the UK alongside the University of Cambridge, the University of Edinburgh, King's College London, Imperial College London and the University of Oxford. (gla.ac.uk)

Moreover, these mock loops enable the development and improvement of techniques for diagnosis and treatment of cardiovascular diseases. (tue.nl)

Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)
Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
Objective: The primary objective of this review is to facilitate a holistic interpretation of eHealth projects aimed at providing self-management support of cardiovascular diseases in the natural setting of patients, thus priming the use of remote monitoring technologies. (utwente.nl)
The reliable identification of such high-risk individuals with no prior history of cardiovascular disease will undoubtedly be of great interest to patients and their providers for preventative care measures. (news-medical.net)
Available therapies may alleviate some symptoms but they cannot reverse the disease and prolong survival of the patients. (wun.ac.uk)
We have shown a change in serotypes and associated potential increases in severity of disease among IPD patients in Alberta, Canada ( 13 ). (cdc.gov)
To validate the model, the team performed the same assessment of blood and feces samples on more than 100 patients in the LIFSCREEN trial who have Li-Fraumeni syndrome, a rare genetic disorder that increases a person's risk for cancer. (medscape.com)
Now, 20 years later, I continue their use because my patients have benefited from the quality products provided by Biotics Research. (bioticsresearch.com)
Using Biotics Research has made a huge difference for both my patients and my practice. (bioticsresearch.com)
Furthermore, statin therapy has a close relationship with different doses of statin in cardiovascular patients. (hindawi.com)

My laboratory is engaged in system biology approaches to investigate cardiovascular diseases. (yale.edu)

Cardiovascular (heart and circulatory) disease is the number one cause of death globally, taking the lives of 17.7 million people every year. (gla.ac.uk)
Glasgow provides an ideal infrastructure for cardiovascular research, with the University at the heart of the Scottish precision medicine ecosystem, which is pioneering global advances in data-driven healthcare. (gla.ac.uk)
Yet, the mouse shares a similar developmental trajectory to the human heart and a comparable four-chamber morphology that greatly enhances its translational value as a model organism, despite the substantial differences in size (Krishnan et al. (springer.com)
However, because good job data is lacking in major U. S. cardiovascular data bases, in order to test for comparable U.S. associations, we are obliged to develop a methodology for linking the data bases concerning job conditions and CHD incidence, respectively (a methodology which also can be applied to occupational diseases other than heart disease). (cdc.gov)
4 A recent analysis by Darby et al suggested a linear increase in the incidence of ischemic heart disease with higher estimated radiation doses to the heart. (ajmc.com)
This has led some researchers to recommend estradiol treatment for women who are fewer than 6 years postmenopausal as a means of preventing heart disease. (sciencedaily.com)
His work will improve therapeutic approaches for tackling genetic and acquired heart disease. (swansea.ac.uk)
In 2020, Chris became the Chair of the National Cardiovascular Network for Wales (NCN), a partnership between Welsh Government and the British Heart Foundation. (swansea.ac.uk)

Our results will show how useful this method can be in bridging the multidisciplinary gap of eHealth research and development, to inform and advance the importance of holistic approaches, while showcasing this approach for the case of self-management in cardiovascular diseases. (utwente.nl)
In this light, effective prevention and management of this disease are among the foremost national healthcare priorities that can be achieved through effective approaches [ 3 ]. (biomedcentral.com)
Detecting cancers early remains an important goal, but current approaches for deciding who should be screened may miss some people with earlier-stage disease. (medscape.com)
5 The development and validation of approaches to minimize this long-term risk is the focus of ongoing research. (ajmc.com)
However, current approaches to environmental hazard assessment do not specifically address CV bioactivity and hazards, despite growing evidence that environmental exposures contribute to the onset, risk, or progression of chronic CV disease. (nih.gov)
Invasive cardiovascular instrumentation can occur through closed- or open-chest approaches. (bvsalud.org)

Analyses were conducted using Cox proportional hazards models with adjustment for individual and area-level sociodemographic covariates and long-term. (lu.se)

Cardio-oncology, or onco-cardiology, is the discipline that focuses on the intersection of cardiovascular disease and cancer. (ajmc.com)

These findings could be important to many other conditions where Nogo is involved, including cancer or diseases of the nervous system. (wun.ac.uk)
Christopher J. Manley, MD, who was not involved in the research, noted that successful cancer screening requires broad implementation, low cost, and ease of use. (medscape.com)
The Center for Experimental Therapeutics works with OHSU's Knight Cancer Institute, Vollum Institute, Knight Cardiovascular Institute, Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Brenden-Colson Center, Center for Regenerative Medicine, Brain Institute, and more. (ohsu.edu)

and Marek Michalak, the faculty's vice-dean of research and a professor in the Department of Biochemistry. (wun.ac.uk)
The immune system has to find the perfect balance to defend the body against foreign invaders without hurting itself or over-reacting to the environment and this can be particularly challenging in the gut, where there is an abundance of food and bacteria," said Dr. Scott, a Senior Scientist at the Ottawa Hospital Research Institute and Professor of Medicine at the University of Ottawa. (sciencedaily.com)
Their donations have now enabled several simultaneous large grants to research, although large grants in this field are otherwise relatively rare in Finland", says Mikko Niemi , member of the Board of Trustees of the Finnish Cultural Foundation and professor of pharmacogenetics at the University of Helsinki. (skr.fi)
Professor Seppo Ylä-Herttuala and a research group received €200,000 for research on developing gene therapy. (skr.fi)

Anatomy3

Organisms1

Diseases36

Chemicals and Drugs20

Analytical, Diagnostic and Therapeutic Techniques and Equipment43

Psychiatry and Psychology8

Phenomena and Processes14

Disciplines and Occupations13

Anthropology, Education, Sociology and Social Phenomena4

Humanities1

Information Science9

Named Groups3

Health Care44

Geographicals3

Coronary16

Mortality14

Clinical34

Cardiac5

20223

Biomarkers1

Diabetes27

Complications3

Metabolic9

Development of cardiovascular diseases2

Mechanisms11

Prevalence of cardiovascular1

Chronic diseases6

Hypertension8

People with cardiovascular disease1

Prevention of cardiovascular disease1

Health39

Biomedical Research1

Centers3

Risks8

Metabolism3

Measuring cardiovascular risk1

Contributes to the development1

Disorders3

Physiology3

Obesity3

Atrial fibrillation1

Field of cardiovascular1

Myocardial3

Stroke4

Human cardiovascular2

Study13

Molecular2

20211

Atherosclerosis3

Inflammation4

Prediction1

Future cardiovascular1

20232

Estimate3

Vascular2

20191

Centre of Research Excellence1

Diagnosis and treatment1

Patients11

Biology1

Heart8

Approaches6

Proportional hazard1

Cardiology1

Cancer3

Professor4