Cardiovascular adiponectin. Medical search. Frequent questions

Circulating adiponectin concentrations increase during caloric restriction in animals and humans, such as in patients with anorexia nervosa. (wikipedia.org)
Furthermore, a recent study suggests that adipose tissue within bone marrow, which increases during caloric restriction, contributes to elevated circulating adiponectin in this context. (wikipedia.org)
Increased circulating adiponectin and insulin sensitivity are usually observed after body fat loss induced by a weight‑loss diet. (hmamedicalclinic.com)
Therefore, the purpose of this study was to ascertain the effects of combined 16‑week PRT and weight‑loss diet on circulating adiponectin and insulin sensitivity index. (hmamedicalclinic.com)
WL resulted in an expected increase in circulating levels of adiponectin ( P = 0.07) and insulin sensitivity. (hmamedicalclinic.com)
In conclusion, in obese women a 16‑week combined PRT and weight‑loss diet is accompanied by significant improvements in different cardiovascular risk factors in spite of a significant decrease of circulating adiponectin. (hmamedicalclinic.com)
of PRT on circulating adiponectin and the physiological role Moreover, it is known that an excess of abdominal adipose tis- of adiponectin on the improvement of metabolic and cardio- sue is a better predictor of the development of insulin resistance, vascular risk factors with either body or fat mass loss are as yet type 2 diabetes and cardiovascular disease than the total amount incompletely understood (1,13). (hmamedicalclinic.com)
Circulating levels of adiponectin may be In the present study, we hypothesized that a twice-weekly the link between visceral obesity and certain related metabolic PRT would be particularly useful in the context of a weight- abnormalities which contribute to the development of insulin loss diet in adult obese women, increasing the visceral fat resistance, type 2 diabetes and atherosclerosis (3,8,9). (hmamedicalclinic.com)
This could yield highly favorable changes in circulating anthropometric variables adiponectin and, as a result, to the metabolic and cardio- Height of the barefoot subjects was measured to the nearest 0.1 cm. vascular risk. (hmamedicalclinic.com)
indeed circulating adiponectin is low in obese insulin-resistant individuals and in other adverse metabolic states (Ye and Scherer 2013 Conversely serum adiponectin increases in lean insulin-sensitive states such as with calorie restriction (CR) in animals and anorexia nervosa (AN) in humans (Combs et al. (mdm2-inhibitors.com)
2003 Reduced circulating adiponectin in obesity likely derives from decreased adiponectin expression and secretion which may result from mitochondrial dysfunction or aberrantly increased inflammation hypoxia or endoplasmic reticulum stress (Ye and Scherer 2013 Far less is known about why serum adiponectin increases in lean states. (mdm2-inhibitors.com)
2013 In striking contrast to WAT MAT markedly increases during CR in animals including humans (Devlin 2011 Thus in this manuscript we investigate the hypothesis that MAT is a source of circulating adiponectin in states of leanness. (mdm2-inhibitors.com)
Bone marrow adipose tissue (MAT) contributes to increased circulating adiponectin, an insulin-sensitizing hormone, during caloric restriction (CR), but whether this occurs in other contexts remains unknown. (frontiersin.org)
Circulating adiponectin was determined by ELISA. (frontiersin.org)
Notably, this was also the only group in which tibial adiponectin expression was lower than in WT mice, suggesting a close association between MAT adiponectin production and circulating adiponectin. (frontiersin.org)

TT Vs TG+GG in the given population, although the proportion of CVDDM attributable to TT genotype was 6.8% in overall study population, a similar risk factor was also observed in GG genotype against TG+TT genotype to confer the risk of developing cardiovascular disease with diabetes (P=0.0017) and GG genotype attributes nearly 50.9% in overall cases. (journalcra.com)
Dyslipidaemia is a known risk factor for developing cardiovascular disease. (edu.au)

The study included 56 individuals with obesity, of whom 30 individuals underwent Roux-en-Y gastric bypass surgery (RYGB) and twenty-six underwent sleeve gastrectomy (SG). (biomedcentral.com)
Obesity (2009) Lifestyle changes such as weight loss and regular physical At present, adiponectin may be the most important and promis- activity are recognized as effective nonpharmacological inter- ing adipocytokine for obtaining a better understanding of the link ventions with beneficial effects on metabolic and cardio vascular between obesity and metabolic and cardiovascular disease (1,2). (hmamedicalclinic.com)
Cardiovascular (CV) risk factors such as hypercholesterolemia, hyperglycaemia, obesity, hypertension, smoking, and aging promote vascular inflammation and endothelial activation [ 7 - 9 ]. (hindawi.com)
Adiponectin may serve as a biomarker of cardiometabolic risk and response to interventions to prevent and manage obesity and its comorbidities in SCBT. (bepress.com)
Low plasma levels of the anti-inflammatory factor adiponectin characterize obesity and insulin resistance. (diabetesjournals.org)
Adiponectin plasma levels and adipose-tissue gene expression were significantly lower in obese subjects and inversely correlated with obesity-associated variables, including high-sensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6). (diabetesjournals.org)
0.05), whereas the inverse correlation between adiponectin plasma levels or adiponectin gene expression in adipose tissue with plasma IL-6 were largely dependent on the clustering of obesity-associated variables. (diabetesjournals.org)
It has been shown that traditional cardiovascular risk factors such as hypertension, obesity, diabetes, dyslipidemia and metabolic syndrome modify the structural and functional characteristics of arteries reducing their compliance and increasing arterial stiffness. (dovepress.com)
11 , 12 Visceral obesity is associated with hyperleptinemia, leptin-resistance and hypoadiponectinemia configuring a high cardiovascular risk phenotype. (dovepress.com)
Metabolic syndrome, driven mainly by obesity, has become a global epidemic, increasing the risk of type 2 diabetes and cardiovascular disease. (nccu.edu)
Obesity promotes a chronic inflammatory state, which contributes to the development of insulin resistance and cardiovascular disease. (bu.edu)
This ARC is intended to promote translational research by bringing basic and clinical research laboratories together to study the cardiovascular consequences of obesity and diabetes. (bu.edu)
The funds from this ARC will be used to 1) initiate collaborative studies in mouse models on mechanisms of obesity-linked cardiovascular diseases and 2) support research where basic science and clinical research labs perform molecular analyses on tissues and cell samples isolated from patient populations. (bu.edu)
Obesity and its comorbidities, including hypertension, hyperlipidemia and type 2 diabetes mellitus, have a devastating impact on vascular function leading to conditions that promote cardiovascular disease. (bu.edu)
Obesity is defined as an expansion of white adipose (WAT) tissue that is associated with low grade inflammation which possibly contributes to the development of health complications such as diabetes, liver pathologies, dyslipidemia, cardiovascular diseases as well as some cancers [ 2 - 4 ]. (springer.com)
Human Preadipocytes (HPAd) provide ideal cell models and facilitate life science research and drug discovery for obesity, diabetes and cardiovascular diseases. (cellapplications.com)
The metabolic syndrome (MetS) is a constellation of metabolic risk factors (including hypertension, dyslipidaemia, abdominal obesity and impaired glucose metabolism), which is associated with a twofold increased risk of cardiovascular disease (CVD) (Ford, 2005), and an even higher risk of T2DM (Grundy, 2008). (bhma.org)
The importance of central obesity with its metabolic, inflammatory and prothrombotic consequences playing a key role in cardiovascular risk, is discussed. (bvsalud.org)
Metabolic Syndrome (MS) is the denomination proposed by the World Health Organization (WHO) 42 , which designates a set of risk factors for cardiovascular diseases (CVDs), such as visceral obesity, dyslipidemia, high hypertension, glucose intolerance and insulin resistance 32 , which frequently are presented together. (bvsalud.org)

However, coronary artery disease has been found to be positively associated with high molecular weight adiponectin, but not with low molecular weight adiponectin. (wikipedia.org)
AIMS: To examine the relevance of genetic and cardiovascular magnetic resonance (CMR) features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD). (imperial.ac.uk)
In human subjects, studies have shown that endothelial dysfunction, recognized as impairments in flow-mediated dilation or endothelial-dependent vasodilation in response to acetylcholine, is predictive of cardiovascular events in patients with hypertension, coronary artery disease, peripheral artery disease, etc. (bu.edu)
Low adiponectin is predictive of the future development of type II diabetes and coronary artery disease. (thepmc.org)
Aim: To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. (bvsalud.org)

Bariatric surgery can alleviate cardiovascular risk via effects on cardiovascular disease (CVD) risk factors such as diabetes mellitus, hypertension, and dyslipidemia. (biomedcentral.com)
Emerging data show that high density lipoprotein cholesterol levels, an established negative risk factor for cardiovascular disease improves after bariatric surgery [ 9 ]. (biomedcentral.com)
The association of this gene with cardiovascular disease (CVD) is studied in various studies , hence the present study was designed to investigate the association of SNP +45T/G and +276G/T in the AdipoQ gene in CVD patients with and without diabetes mellitus and normal controls in North Coastal Andhra Population. (journalcra.com)
Methods: The present study has a total 274 subjects, in which group 1 has normal controls without any complications (n=99), group 2 has cardiovascular disease subjects with diabetes (CVDDM) (n=102), and group 3 has cardiovascular disease subjects without diabetes (CVDNDM) (n=73). (journalcra.com)
The TT genotype against TG+GG genotype of the 276 G/T polymorphism was observed to confer increased risk to develop cardiovascular disease with diabetes (P=0.000001). (journalcra.com)
Conclusion: The SNP 276 G/T of adiponectin gene was observed to confer increased risk to develop cardiovascular disease among diabetes subjects. (journalcra.com)
An autoimmune disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the cardiovascular system. (mcw.edu)
P = .031), smaller chamber volumes, and lower stroke volume, but higher contractility.ConclusionsThe results of this study support a causal role of low birth weight in cardiovascular disease, even after accounting for the influence of the intrauterine environment. (imperial.ac.uk)
This suggests that individuals with a low birth weight may benefit from early targeted cardiovascular disease prevention strategies, independent of whether this was linked to an adverse intrauterine environment during gestation. (imperial.ac.uk)
Introduction and objectives: Telomeres are noncoding regions located at the end of chromosomes and their shortening has been associated with risk factors and cardiovascular disease. (unav.edu)
Due in large part to the increased prevalence of cardiovascular disease, it is estimated that life expectancy declines by 3 years for those with a Body Mass Index (BMI) over 30 and 10 years for those with a BMI over 40. (bu.edu)
In spite of all the evidence that cigarette smoke stimulates atherogenesis and lipoprotein oxidation may play an important role [ 9 ], very little is known about the biological processes induced by smoke that contribute to increased cardiovascular disease. (biomedcentral.com)
NaturalNews) Researchers at the Medical College of Georgia at Georgia Health Sciences University have published evidence that cardiovascular disease and diabetes risk is present in the blood fractions of adolescents who consume a lot of fructose, a scenario that worsens in the face of excess belly fat. (ironmagazine.com)
Nutrition experts recommend limiting natural fructose consumption to no more than 25 grams per day at an early age to minimize the risk of cardiovascular disease and diabetes in later life. (ironmagazine.com)
Insulin resistance results in increasing A1C & each 1% increase of AIC precedes the 8% increased CHF & a 17% increase in cardiovascular disease. (thepmc.org)
Cardiovascular disease rose progressively as fasting plasma glucose and post-load glucose levels rose above 75 mg/dL = 4.2 mmol/liter (Coutinho M, Gerstein HC, Wang Y, Usuf S. The relationship between glucose and incident cardiovascular events. (thepmc.org)
25 kg/m 2 on hospital admission to manage COVID-19 disease in patients belonging to a cardiovascular risk program in the city of Cali, Colombia, during the year 2020. (unilibre.edu.co)
The cluster of factors focused on cardiovascular disease and eventually diabetes is named MS. Several definitions of MS are analyzed and compared. (bvsalud.org)
Introduction: Metabolic syndrome (MS) is a complex pathology that combines several risk factors for cardiovascular disease. (bvsalud.org)
Obese Hispanic adolescents (OHAs) with dysglycemia have increased cardiovascular disease risk burden. (medscape.com)
In population studies, NAFLD was found to be independently associated with increased risk of cardiovascular disease (CVD). (medscape.com)
cardiovascular disease. (bvsalud.org)
Recently, it has been recognized dren and Adolescents9, recommending that changes in the serum lipid levels in changes in the desirable values of lipi- childhood may be predictive of the oc- ds, with reductions in the total choleste- currence of cardiovascular disease in rol and LDL-C values and increase in the adults. (bvsalud.org)

Background and Objective: Adiponectin gene single nucleotide polymorphism (SNP) in the exon 3 and intron 4 is a well characterized SNP which has previously been linked to various diseases including cardiovascular diseases. (journalcra.com)
However, lowering LDL levels is a common clinical practice to reduce oxidation and the risk of major events in patients with cardiovascular diseases (CVD). (hindawi.com)
Cardiovascular diseases (CVD) are the leading cause of mortality in the Western population [ 1 ]. (hindawi.com)
Long-term NHS research has shown that weight gain and being overweight or obese are important risk factors for type 2 diabetes, cardiovascular diseases, certain types of cancers, and premature death. (aphapublications.org)
There is no evidence about the benefits of MS treatment on the prevention of cardiovascular diseases or diabetes. (bvsalud.org)
Subjects with with insulin dependent diabetes mellitus or subjects with insulin independent diabetes mellitus taking oral hypoglycemic therapy Subjects with uncontrolled chronic cardiovascular, endocrine, autoimmune, psychiatric, and autoimmune diseases or other condition based on the investigator judgement. (who.int)

We also compared the various biomarkers of metabolism, inflammation, coagulation, and of myocardial necrosis divided by quartiles of adiponectin. (usp.br)

Total serum adiponectin levels were measured by immunoassay. (who.int)
The rare G allele of +45T>G occurred more frequently than the common T allele in T2DM patients compared with controls, and was associated with lower serum adiponectin levels. (who.int)

T2DM patients had reduced adiponectin levels compared with controls. (who.int)

High-molecular-weight adiponectin was further found to be associated with a lower risk of diabetes with similar magnitude of association as total adiponectin. (wikipedia.org)
High molecular weight adiponectin levels are inversely associated with adiposity in pediatric brain tumor survivors. (bepress.com)

2011 most studies in mice and humans find that prolonged CR or extensive weight loss increases serum adiponectin without affecting adiponectin expression or secretion from WAT (Behre et al. (mdm2-inhibitors.com)

Adiponectin is secreted from adipose tissue (and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones. (wikipedia.org)
Adiponectin has been shown to be secreted principal y visceral fat in older men (11) and women (12), improving by visceral adipose tissue (VAT), the size of this visceral fat depot insulin sensitivity (11). (hmamedicalclinic.com)
The antidiabetic thiazolidinediones (TZDs) also promote MAT expansion and hyperadiponectinemia, even without increasing adiponectin expression in white adipose tissue (WAT). (frontiersin.org)
To elucidate the relationship between plasma levels of adiponectin, adiponectin gene expression in adipose tissue, and markers of inflammation, we obtained blood samples, anthropometric measures, and subcutaneous adipose tissue samples from 65 postmenopausal healthy women. (diabetesjournals.org)

Both conditions are strongly linked to leptin and adiponectin, the most prominent adipocyte-derived protein hormones. (ox.ac.uk)

In conclusion, our data suggest a transcriptional mechanism leading to decreased adiponectin plasma levels in obese women and demonstrate that low levels of adiponectin are associated with higher levels of hs-CRP and IL-6, two inflammatory mediators and markers of increased cardiovascular risk. (diabetesjournals.org)

These observations identify MAT as an endocrine organ that contributes significantly to increased serum adiponectin during CR and perhaps in other adverse states. (mdm2-inhibitors.com)
AN subjects had significantly higher MAT of the L4 vertebrae femoral metaphysis and femoral diaphysis and increased total and P7C3-A20 HMW serum adiponectin despite decreased total fat mass (Table 1). (mdm2-inhibitors.com)
However, rosiglitazone significantly increased adiponectin protein expression in WAT, suggesting that WAT contributes to hyperadiponectinemia in this context. (frontiersin.org)
SBP, PP, cfPWV were significantly higher in subjects with high leptin and low adiponectin (group 2). (dovepress.com)

In conclusion, individuals with Iranian or Indian ancestries may have lower adiponectin levels compared to Europeans. (edu.au)

However, at present both the effect being an important correlate of plasma adiponectin levels (5). (hmamedicalclinic.com)

Adiponectin is an adipocyte-derived protein with anti-diabetic, anti-atherogenic and anti-inflammatory action, but there are few studies on its association with cardiovascular and metabolic risk factors in different ethnic groups in Australia. (edu.au)
Adiponectin is an anti-atherogenic factor. (bvsalud.org)

Fasting glucose was the only metabolic biomarker with a significant and independent predictive value for cardiovascular outcomes. (usp.br)
Can Adiponectin be a biomarker for Ethnic heterogeneity in Diabetes Mellitus? (intechopen.com)

Adiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels and fatty acid breakdown. (wikipedia.org)
Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. (wikipedia.org)
These potential signaling mediators include glucose, free fatty acids, autonomic nerves, fat-derived hormones (eg, adiponectin), and the gut hormone glucagonlike peptide-1 (GLP-1). (medscape.com)
We hypothesize that pregnane X receptor deficiency results in impaired adiponectin signaling leading to insulin resistance and glucose intolerance with more prominent race and sex differences. (nccu.edu)
Cardiovascular health score was defined by the American Heart Association as a composite score of 7 key risk factors (smoking status, physical activity, diet, body mass index, blood pressure, total cholesterol, and fasting blood glucose) with 0 to 2 points for each factor. (unav.edu)
In comparison to glimepiride, pioglitazone treatment led to a significant increase in HDL cholesterol and adiponectin, decrease in fasting glucose and insulin, significant higher reduction of triglycerides, and a significant higher reduction in the LDL/HDL ratio. (natap.org)
The study detailed an analysis of 559 adolescents, aged 14 to 18 and detailed cardiovascular risk factors including high blood pressure, fasting glucose, insulin resistance and blood inflammatory factors. (ironmagazine.com)
Since diabetes is associated with cardiovascular and kidney complications, we investigated the influence of SBE on blood glucose, blood pressure and renal function in some experimental animal paradigms. (endocrine-abstracts.org)

Many studies have found adiponectin to be inversely correlated with body mass index in patient populations. (wikipedia.org)
In conclusion, HMW adiponectin is inversely correlated with adiposity in SCBT. (bepress.com)

0.05) in WL+RT group, whereas an improvement in different cardiovascular risk factors (insulin sensitivity, low‑density lipoprotein cholesterol (LDL‑C), etc.) was observed. (hmamedicalclinic.com)

We tested the hypothesis that high molecular weight (HMW) adiponectin levels, the more biologically active form of adiponectin, were associated with adiposity in SCBT similarly to non-cancer controls. (bepress.com)

Adiponectin is a 244-amino-acid-long polypeptide (protein). (wikipedia.org)
Adiponectin is secreted into the bloodstream, where it accounts for about 0.01% of all plasma protein at around 5-10 μg/mL. (wikipedia.org)
So far, two receptors have been identified with homology to G protein-coupled receptors, and one receptor similar to the cadherin family: Adiponectin receptor 1 (AdipoR1) Adiponectin receptor 2 (AdipoR2) T-cadherin - CDH13 These have distinct tissue specificities within the body and have different affinities to the various forms of adiponectin. (wikipedia.org)
In addition, mice exposed to smoke have increased levels of Monocyte Chemoattractant Protein-1 in circulation and in the heart/aorta tissue, have increased macrophages in the arterial walls, and have decreased levels of adiponectin, an EC-protective protein. (biomedcentral.com)
Adiponectin also amplifies fat metabolism while sparing carbohydrate and/or protein metabolism, allowing the body to stay the course during extended periods, especially over great distances. (popular-archaeology.com)
In this study, we aimed at examining how added sugar and sugar-sweetened beverage intake associate with 136 measured plasma proteins and C-reactive protein in the Malmö Diet and Cancer-Cardiovascular Cohort ( n = 4382), and examine if the identified added sugar- and SSB-associated proteins associate with T2D incidence. (lu.se)

Nous avons génotypé les deux polymorphismes mononucléotidiques du gène ADIPOQ chez 140 patients atteints de DNID sans lien de parenté et 66 témoins non diabétiques en recourant à l'analyse du polymorphisme de longueur des fragments de restriction par réaction en chaîne de polymérase. (who.int)

RESULTS Anorexia nervosa is associated with increased serum adiponectin and MAT Previous studies P7C3-A20 have not assessed both serum adiponectin and BM adiposity in a single cohort of AN subjects. (mdm2-inhibitors.com)
Partial correlations and multivariable regression analyses assessed the relationship between HMW adiponectin and adiposity. (bepress.com)
Our results also highlighted age, truncal adiposity and dietary glycemic index as other determinants of serum adiponectin, however the extent to which these factors influence adiponectin concentrations may vary across ethnicities. (edu.au)

High adiponectin levels correlate with a lower risk of diabetes mellitus type 2. (wikipedia.org)
Results: Adiponectin did not correlate independently with CV risk, either on univariate analysis or on the multiple regression models of Cox. (usp.br)

Two huge contributors to that enhanced metabolism are hormones - in this case, estrogen and adiponectin, which are typically present in higher quantities in female bodies than in male. (popular-archaeology.com)

Higher fasting insulin levels increase cardiovascular events 550% and are more predictive than high LDL or Apo B, or low HDL. (thepmc.org)

Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. (ox.ac.uk)

Initially, three adiponectin molecules bind together to form a homotrimer. (wikipedia.org)
Adipocytes are a rich source of molecules that modulate cardiovascular and metabolic risk ( 1 , 2 ). (diabetesjournals.org)

The change in CEC correlated with the change in apo A-I (r = 0.39, p = 0.02) and adiponectin levels (r = 0.35, p = 0.03). (biomedcentral.com)
Plasma levels of adiponectin are lower in obese subjects than in lean subjects. (wikipedia.org)
Humans with lower levels of adiponectin have reduced cognitive function. (wikipedia.org)
As high leptin levels and low levels of adiponectin have been implicated in inflammation, one expects adiponectin to be positively associated with RTL while leptin should be negatively associated. (ox.ac.uk)
In this study, we determined the serum levels of adiponectin in a sample of patients hospitalized with acute coronary syndromes (ACS), and subsequently we evaluated the association with the cardiovascular events during the follow-up phase. (usp.br)
In conclusion, in the elderly, the presence at the same time of high leptin levels and low adiponectin levels seems to have synergic effects on arterial stiffness. (dovepress.com)
Published in the Journal of Nutrition, scientists determined that high dietary fructose consumption results in lower levels of cardiovascular protectors such as HDL cholesterol and adiponectin, due in part to how the body metabolizes the fruit-based mega-sweetener at the cellular level. (ironmagazine.com)
This cross-sectional study evaluated ethnic differences in adiponectin levels and its association with age, gender, body composition and diet in 89 adult Australians of European (n = 28), Indian (n = 28) and Iranian (n = 33) ancestries. (edu.au)
0.001), ethnicity (p = 0.001), age (p = 0.001) and dietary glycemic index (p = 0.04) could predict 50% of the variance in adiponectin levels (R2 = 0.504). (edu.au)
Ethnicity was found as an independent factor affecting adiponectin levels. (edu.au)

A five-year follow- up study of Swedish men indicated that elevated plasma cortisol and low testosterone were prospectively associated with increased incidence of cardiovascular-related events and Type 2 Diabetes Mellitus (T2DM) (Rosmond et al, 2003). (bhma.org)

2011 Thus in lean states such as CR or AN the paradoxical increase in serum adiponectin can occur without greater expression or secretion from WAT or decreased adiponectin clearance. (mdm2-inhibitors.com)
This striking increase P7C3-A20 strongly suggests that during CR MAT exists in an amount that has clear potential to exert systemic effects through secretion of endocrine factors such as adiponectin. (mdm2-inhibitors.com)
Table 1 MAT WAT BMD and serum adiponectin in subjects with Anorexia Nervosa and healthy controls The relative expression and secretion of adiponectin is greater from MAT than from WAT The ability of MAT to express or secrete adiponectin has not been addressed. (mdm2-inhibitors.com)

It is so important for cardiovascular and metabolic health, brain development and injury recovery. (popular-archaeology.com)

In a logistic binary regression on the entire population, considering subclinical vascular damage as a dependent variable and age, gender, MAP, fat mass%, triglycerides, HDL cholesterol and category of subjects with high leptin and low adiponectin as independent variables, MAP and category of subjects with high leptin and low adiponectin were significant predictors (OR, respectively, 1.09 and 3.61). (dovepress.com)

Adiponectin in an adipokine that is inversely associated with the fat mass, and has been linked to cardiometabolic risk stratification in the general population. (bepress.com)
The study population was subdivided in 2 subgroups according to adipokine patterns: group 1 included patients with high adiponectin and low leptin, and group 2 patients had high leptin and low adiponectin. (dovepress.com)

2006 Indeed adiponectin expression in WAT decreases in human subjects with AN (Dolezalova et al. (mdm2-inhibitors.com)

The cumulative loss of fat leads to a decrease in adipose-derived adiponectin and leptin. (medscape.com)

Conclusions: Adiponectin was not an independent risk factor for cardiovascular risk in this sample of ACS patients. (usp.br)
We conducted a meta-analysis of randomized controlled trials (RCTs) to explore the effects of MSD on glycemic control, weight loss and cardiovascular risk factors in T2D patients. (nature.com)
The present meta-analysis provides evidence that MSD improves outcomes of glycemic control, body weight and cardiovascular risk factors in T2D patients. (nature.com)
La présente analyse récapitule les facteurs pathologiques majeurs liant l'obésité au diabète, en se concentrant sur les données épidémiologiques actuelles relatives aux patients diabétiques obèses dans le monde arabe, l'étiologie de la maladie et les déterminants génétiques du diabète et de l'obésité. (who.int)

The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health. (mdm2-inhibitors.com)

Conclusions: An inverse association between cardiovascular health score and short telomeres was found especially for men older than 55 years in the SUN population. (unav.edu)

In conclusion, the presented study gives evidence of an anti-inflammatory and potential antiatherogenic effect of pioglitazone that is indicated by improvements in several traditional and nontraditional cardiovascular risk markers and carotid IMT, independent of an improvement in long-term glycemic control. (natap.org)

Anatomy7

Organisms2

Diseases7

Chemicals and Drugs20

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Phenomena and Processes9

Health Care3

Circulating15

Developing cardiovascular disease2

Obesity19

Coronary artery5

Disease23

Diseases6

Biomarkers1

Serum adiponectin levels2

Reduced adiponectin levels1

Molecular weight adiponectin2

Affecting adiponectin expression1

Adipose tissue4

Leptin and adiponectin1

Increased cardiovascular risk1

Significantly4

Lower adiponectin1

Plasma adiponectin1

Anti-atherogenic2

Biomarker2

Glucose8

Inversely correlated2

Insulin sensitivity1

Biologically active form1

Protein6

AdipoQ1

Adiposity3

Correlate2

Metabolism1

Predictive1

Telomere length1

Molecules2

Levels10

Diabetes mellitus1

Secretion3

Metabolic health1

Cholesterol1

Adipokine2

Decreases1

Decrease1

Patients4

Hormone1

Conclusions1

Conclusion1