Cardiometabolic syndrome role in acquiring the metabolic syndrome metabolic syndrome is central obesity. Medical search. Frequent questions

Insulin resistance, metabolic syndrome, and prediabetes are closely related to one another and have overlapping aspects. (wikipedia.org)
Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes. (wikipedia.org)
There is debate regarding whether obesity or insulin resistance is the cause of the metabolic syndrome or if they are consequences of a more far-reaching metabolic derangement. (wikipedia.org)
Rather than total adiposity, the core clinical component of the syndrome is visceral and/or ectopic fat (i.e., fat in organs not designed for fat storage) whereas the principal metabolic abnormality is insulin resistance. (wikipedia.org)
Central obesity is a key feature of the syndrome, as both a sign and a cause, in that the increasing adiposity often reflected in high waist circumference may both result from and contribute to insulin resistance. (wikipedia.org)
PCOS is a heterogeneous disease characterized by hyperandrogenism, dysfunctional ovulation, and polycystic ovary morphology, accompanied by metabolic abnormalities, such as insulin resistance (IR) and obesity. (biomedcentral.com)

Heterogeneity occurs in most glucose intolerance disorders, including diabetes mellitus syndromes. (medscape.com)
We then reviewed whether the reported changes in gut bacterial members found to be established by complex carbohydrates would benefit or harm the cardiometabolic and immunological health of the host taking into account the alterations in the microbiome composition and abundance known to be associated with obesity and its associated disorders. (frontiersin.org)
I sincerely hope all of us will continue to work hard on finding practical solutions for all of these metabolic disorders. (endocrineconferences.com)
Epidemiological studies indicate a bidirectional association between metabolic disturbances, including obesity and related pathological states, and mood disorders, most prominently major depression. (researchsquare.com)
The global prevalence of two medical conditions constituting a major burden on public health systems is on unrelenting rise over the last decades: obesity-related cardiometabolic diseases and mood disorders. (researchsquare.com)
Obesity-related conditions include high blood pressure, high cholesterol, type 2 diabetes, breathing disorders such as asthma and sleep apnea, polycystic ovary syndrome (in females), and joint pathology. (tonixpharma.com)
These professionals have achieved breakthroughs in scientific discoveries and clinical care benefitting people with hundreds of conditions, including diabetes, thyroid disorders, obesity, hormone-related cancers, growth problems, osteoporosis, and infertility. (eurekalert.org)
Cardiometabolic disorders may worsen Covid-19 outcomes. (biomedcentral.com)
This makes it difficult to disentangle independent associations Covid-19 may have with single components of cardiometabolic multimorbidity, defined here as a group of main metabolic disorders that increase the risk of cardiovascular events, such as diabetes, hypertension and dyslipidaemia. (biomedcentral.com)
Gestational diabetes mellitus (GDM), characterized by hyperglycemia that develops during pregnancy, increases the risk of fetal macrosomia, childhood obesity and cardiometabolic disorders later in life. (biomedcentral.com)

filled out a questionnaire referring to major cardiovascular risk factors: smoking, obesity, hypertension, and dyslipidemia. (pharmaceuticalintelligence.com)
the most frequent correlation was found for obesity and hypertension. (pharmaceuticalintelligence.com)
We collected and compared data retrospectively from patients hospitalized for Covid-19 with and without diabetes, and with and without cardiometabolic multimorbidity (defined as ≥ two of three risk factors of diabetes, hypertension or dyslipidaemia). (biomedcentral.com)
We, instead, hypothesized that people with diabetes may differ from those without diabetes in their clinical presentation, course and prognosis of Covid-19 due to the propensity of diabetes to cluster with other cardiometabolic risk factors, such as hypertension and/or dyslipidaemia, which contribute to the increased pro-inflammatory and hypercoagulable states of people with diabetes. (biomedcentral.com)
The results include overlapping associations between family history of different types of cardiometabolic conditions (such as type 2 diabetes and coronary artery disease), and their risk factors (obesity, hypertension), where adults with a family history of 1 ODHB exhibited 1.1 to 5.6 times (1.5, on average) the odds of having a different ODHB. (cdc.gov)
A component of this syndrome-hypertension-is decidedly associated with type 2 diabetes ( 2 ). (silverchair.com)

Type 2 diabetes mellitus is a common chronic disease which develops insidiously over time, and is associated with obesity, nutritional imbalance (high fructose beverages, high starch and processed foods, carbohydrate excess intake, and an imbalance of proinflammatory to anti-inflammatory polyunsaturated fatty acids), which makes it an acquired and manageable disease. (pharmaceuticalintelligence.com)

The prevalence of metabolic syndrome and central obesity increased with age, with the highest rates seen among middle-aged and older adults [ 5 ]. (biomedcentral.com)

Treatment for dyslipidemia, a metabolic complication independently associated with HIV and antiretroviral therapy (12-14), includes dietary management (6, 15-21). (ohtn.on.ca)

Dietary supplementation with complex carbohydrates is known to alter the composition of gut microbiota, and optimal implementation of the use of these so called "prebiotics" could be of great potential in prevention and possibly treatment of obesity and associated cardiometabolic and inflammatory diseases via changes in the gut microbiota. (frontiersin.org)
Metabolic syndrome can lead to several serious and chronic complications, including type-2 diabetes, cardiovascular diseases, stroke, kidney disease and nonalcoholic fatty liver disease. (wikipedia.org)
As adults, our health can be influenced by a range of lifestyle and environmental factors, increasing the risk for developing a series of non-communicable diseases such as type 2 diabetes, heart disease and obesity. (mdpi.com)
Caloric restriction and intermittent fasting have been shown to be tratamiento coadyuvante novel and beneficial strategies in neurodegenerative diseases, through immune, metabolic, and physiological mechanisms. (bvsalud.org)
Sirius Pixels UHDe HEVC Encoder also, when the epub nuclear receptors as molecular targets for cardiometabolic and central nervous system diseases solvay pharmaceuticals conferences is not marketed, the code's abnormalities trigger sequentially shown. (siriuspixels.com)
These epub nuclear receptors as molecular targets for cardiometabolic and central nervous system diseases solvay pharmaceuticals bloodletting polypeptides have increased generally generally of cardiac eye and blood response. (siriuspixels.com)
This annual award honors an internationally recognized clinical investigator who has contributed significantly to understanding the pathogenesis and therapy of endocrine and metabolic diseases. (eurekalert.org)
Adolescents and young adults with prediabetes also present an unfavorable cardiometabolic risk profile, putting them both at increased risk of type 2 diabetes and cardiovascular diseases. (cdc.gov)
Obesity has reached epidemic proportions globally and is a major contributor to the global burden of chronic diseases. (researchpaper.sbs)
Antiretroviral therapy (ART) in HIV carriers increased the life expectancy of this population, favoring the emergence of cardiovascular and metabolic diseases and cancer as the main causes of death. (clinmedjournals.org)
On the other hand, the lengthening of life for a longer time facilitated the appearance of diseases related to increasing age, among which we can include cardiovascular and metabolic diseases and cancer, which now emerge as the main causes of death in this population [ 2 ]. (clinmedjournals.org)
Childhood obesity is reported to be associated with the risk of many diseases in adulthood. (biomedcentral.com)
Therefore, ensuring that childhood obesity does not persist into later life might be useful for reducing the detrimental effects of childhood obesity on adult diseases. (biomedcentral.com)

Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. (wikipedia.org)
HPA-axis dysfunction may explain the reported risk indication of abdominal obesity to cardiovascular disease (CVD), type 2 diabetes and stroke. (wikipedia.org)
Metabolic syndrome is defined by a collection of risk factors that strongly predict the onset of type 2 diabetes later in life ( 1 ). (silverchair.com)

The western dietary pattern, obese-related anthropometric parameters, and most components of metabolic syndrome are positively associated with CRP levels and NLR in men and women with metabolic syndrome. (biomedcentral.com)

Research shows that Western diet habits are a factor in development of metabolic syndrome, with high consumption of food that is not biochemically suited to humans. (wikipedia.org)
The aim of this study was to investigate the impact of baseline skeletal muscle mass and changes in skeletal muscle mass over time on the development of metabolic syndrome in a large population-based 7-year cohort study. (biomedcentral.com)

Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). (wikipedia.org)
Metabolic syndrome is defined by central obesity, increased systolic and diastolic blood pressure (BP), decreased high-density lipoprotein cholesterol (HDL-C), increased serum triglycerides (TG), and elevated fasting blood glucose (FBG). (biomedcentral.com)

The goal of the double-blind POWER study is to assess whether intranasal administration of oxytocin will decrease weight as a consequence of decreased caloric intake and increased energy expenditure, and improve metabolic risk markers in adolescents with obesity. (tonixpharma.com)
The objective of the study was to determine the association of dietary patterns, anthropometric measurements, and metabolic parameters with inflammatory markers in middle-aged and older adults with metabolic syndrome in Taiwan. (biomedcentral.com)
The increased levels of inflammatory markers have also been strongly correlated with both central obesity and metabolic syndrome. (biomedcentral.com)
Weight, body composition, and cardiometabolic risk markers were assessed. (hif-signaling.com)

We conclude that supplemental complex carbohydrates that increase Bifidobacteria and Lactobacilli, without increasing the deleterious Bacteroides , are most likely promoting cardiometabolic and immunological health in obese subjects. (frontiersin.org)
However, few studies have investigated the correlation of reduction in epicardial adipose tissue (EAT) with improvement of IR index after weight loss in obese non-diabetic men with metabolic syndrome (MetS). (biomedcentral.com)
that are obese and at GTPL8918 increased cardiovascular risk, inflammation appears to be a key feature of both of these syndromes. (sirnalibrary.com)

The pathogenic role played in the syndrome by the excessive expansion of adipose tissue occurring under sustained overeating, and its resulting lipotoxicity was reviewed by Vidal-Puig. (wikipedia.org)

evidence suggests that taking a proactive approach to nutrition can improve health outcomes related to the adverse metabolic, cardiovascular, and psychological complications that result from HIV and antiretroviral therapy (ART) (31). (ohtn.on.ca)
Energy expenditure and sitting time, measured via Actiheart and activPAL monitors, respectively, as well as cardio-metabolic and anthropometric outcomes and other outcomes relating to health and work performance, will be assessed in 10 randomly selected participants. (biomedcentral.com)
We investigated features and Covid-19 outcomes for patients with or without diabetes, and with or without cardiometabolic multimorbidity. (biomedcentral.com)
They are at increased risk of adverse outcomes, likely because diabetes clusters with other cardiometabolic conditions. (biomedcentral.com)

The mechanisms of the complex pathways of metabolic syndrome are under investigation. (wikipedia.org)
Metabolomics may identify biological pathways predisposing children to the risk of overweight and obesity. (nature.com)
Additionally, the inhibition of the hypothalamic DA release observed in this study further supports the role of dopaminergic pathways as key targets for novel pharmacological approaches in the management of migraine attacks. (researchgate.net)
The alteration of metabolic pathways is a critical strategy for cancer cells to attain the traits necessary for metastasis in disease progression. (biomed.news)

The findings from such a trial are expected to inform discussions regarding the potential of sit-stand desks at work to alleviate the harm to cardio-metabolic health arising from prolonged sitting. (biomedcentral.com)
Little is known about dietary patterns in Guatemalan adults and how dietary patterns are associated with cardio-metabolic disease (CMD) risk. (biomedcentral.com)

Obesity has become a worldwide epidemic. (sirnalibrary.com)

In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy and overweight in early childhood in four European birth cohorts. (nature.com)
More than two-thirds of the U.S. population suffers from obesity or is overweight 1 ," said Seth Lederman, M.D., Chief Executive Officer of Tonix Pharmaceuticals. (tonixpharma.com)
The objectives were to find the prevalence of overweight and obesity in the urban population of Jamnagar and to explore the effect of dietary factors on the weight status of the people. (researchpaper.sbs)
The prevalence of overweight and obesity was found to be 22.04% and 5.20%, respectively. (researchpaper.sbs)
Childhood overweight and obesity often persist in adulthood, which increases the risks of premature mortality and physical morbidity across the lifespan [ 2 ]. (biomedcentral.com)

Obesity was defined as having age- and sex-specific body mass index (calculated as weight in kilograms divided by height in meters squared) in the 95th percentile or higher in adolescents or 30 or higher in young adults. (cdc.gov)

The key sign of metabolic syndrome is central obesity, also known as visceral, male-pattern or apple-shaped adiposity. (wikipedia.org)

Childhood obesity is a serious health problem in the United States, with approximately one in five children and adolescents affected. (tonixpharma.com)

We identified potential causal effects of childhood obesity on 60 adult traits (27 disease-related traits, 27 lifestyle factors, and 6 other traits). (biomedcentral.com)
With a large amount of GWAS summary data deposited in public databases, two-sample MR analysis provides a cost-efficient way to investigate the potential causal effects of childhood obesity on adult traits. (biomedcentral.com)

Fasting insulin levels and cardiometabolic risk factors across glycemic abnormality phenotypes were also compared. (cdc.gov)

The adjusted prevalence of prediabetes is higher in male individuals and in people with obesity. (cdc.gov)

Endocrine Meeting 2018 welcomes all the Endocrinologists , Diabetologists, and other medical & clinical experts working the arena of Endocrinology , Metabolic Syndrome and related field to this upcoming Euro Endocrinology Meeting at Paris, France. (endocrineconferences.com)

Future research should take into account the different causes of obesity and its adverse health conditions, which in turn have drastic effects on the microbiome balance. (frontiersin.org)
Hence, a metabolic signature at birth may help elucidate the mechanisms involved in metabolic health later in life. (nature.com)
Obesity continues to be a major worldwide health problem, despite the efforts of the medical community. (cambridge.org)
Good nutrition plays an important role in the maintenance of overall health, regardless of HIV status (29, 30). (ohtn.on.ca)
Whether improvements in cardiometabolic health following weight loss (WL) are associated with changes in regional body fat distribution (gluteal vs. -android) is not well documented. (karger.com)
Does pharmacists' changing role offer value for money for the health system? (fip.org)
Her work created a paradigm shift by demonstrating how rare and low frequency genetic variants contribute to cardiometabolic health and disease. (eurekalert.org)
However, evidence from developed nations has reported a protective effect of healthy dietary patterns such as plant-based diets (PBDs) on cardiometabolic health. (sun.ac.za)
Obesity is a worldwide health problem. (biomedcentral.com)
Mitochondria are central hubs for cellular metabolism, coordinating a variety of metabolic reactions crucial for human health. (biomed.news)

The last few years have brought a rising body of evidence that adiponectin is a multipotential protein with anti-inflammatory, metabolic, anti-atherogenic, and reactive oxygen species (ROS) protective actions. (encyclopedia.pub)
Further analyses have shown its anti-inflammatory and anti-apoptotic roles in human cells. (encyclopedia.pub)
Thus, assessing the inflammatory burden could be an easy method to identify those subjects who have increased cardiometabolic risk. (sirnalibrary.com)

of inflammation and cardiovascular risk, have a higher cardiometabolic risk than those without. (sirnalibrary.com)

Here we tested the hypothesis that the enhanced activation of brown fat tissue (BAT), known to beneficially regulate obesity and accompanying dysfunctional metabolic states, is also paralleled by an alteration of affective behaviour. (researchsquare.com)

A further longitudinal study is needed to elucidate the casual relationship between low muscle mass and metabolic syndrome incidence across the full age range of the population, beyond the sarcopenia context. (biomedcentral.com)

In the U.S., about 25% of the adult population has metabolic syndrome, a proportion increasing with age, particularly among racial and ethnic minorities. (wikipedia.org)

The current role of CMR imaging in clinical cardiology is reviewed, including coronary artery disease, congenital heart disease, nonischemic cardiomyopathies and valvular disease. (hif-signaling.com)

The main cause of obesity is energetic imbalance due to increased caloric intake and little expenditure. (hrb.ie)

Exome-Based Case-Control Analysis Highlights the Pathogenic Role of Ciliary Genes in Transposition of the Great Arteries. (stanford.edu)

citation needed] Recent research indicates prolonged chronic stress can contribute to metabolic syndrome by disrupting the hormonal balance of the hypothalamic-pituitary-adrenal axis (HPA-axis). (wikipedia.org)
A hormonal disorder that causes enlarged ovaries with cysts ( polycystic ovary syndrome or PCOS). (webmd.com)
This induces metabolic and hormonal changes that. (hrb.ie)

Glucose intolerance is an umbrella term for a group of metabolic conditions that result in higher than normal blood glucose levels. (medscape.com)

Multivariate logistic regression was performed to evaluate the association of dietary patterns, anthropometric measurements, and metabolic parameters with C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) in men and women with metabolic syndrome. (biomedcentral.com)
WL achieved via a hypocaloric, nutritionally complete, higher protein meal plan is effective in reducing body fat in the android, gynoid, and visceral depots, which relate to cardiometabolic improvements. (karger.com)

We used upstream stimulatory factor 1 (USF1) knock-out mice as a genetic model of constitutively activated BAT and positive cardiometabolic traits, and we found a reduction of depression-like and anxiety-like behaviours associated with USF1 deficiency. (researchsquare.com)

The metabolites identified here may assist in the identification of children at risk of developing obesity and improve understanding of mechanisms involved in postnatal growth. (nature.com)
However, the biological mechanisms mediating the comorbid relationship between the deranged metabolic and mood states remain incompletely understood. (researchsquare.com)

During 7 years of follow-up, 20.1% of subjects developed metabolic syndrome. (biomedcentral.com)
Multi-faceted Evaluations Following Weight Reduction in Subjects with Metabolic Syndrome NCT01065753 on Feb 8, 2010). (biomedcentral.com)
A total of 26,016 subjects aged ≥35 y with metabolic syndrome were recruited from Mei Jau institution between 2004 and 2013 for a cross sectional study. (biomedcentral.com)
Data from this manuscript indicate that both of these definitions identify subjects with increased cardiometabolic risk. (sirnalibrary.com)

Adiponectin connects energy balance regulation in the central nervous system and peripheral tissues [ 10 ] . (encyclopedia.pub)

Osmotic adjustment and alteration of polyamines (PAs) have been suggested to play roles in plant adaptation to water deficit/drought stress. (sirnalibrary.com)

Background Neurocognitive impairment is a common complication of congenital heart disease (CHD) as well as acquired cardiovascular disease. (stanford.edu)

Background Family history reflects the complex interplay of genetic susceptibility and shared environmental exposures and is an important risk factor for obesity, diabetes, and heart and blood conditions (ODHB). (cdc.gov)

Metabolic syndrome is commonly associated with inflammation. (biomedcentral.com)
The underlying factors of inflammation in metabolic syndrome are not fully understood. (biomedcentral.com)
However, the underlying factors of inflammation in metabolic syndrome are not fully understood. (biomedcentral.com)
Obesity defined by body mass index (BMI) and waist circumference was associated with inflammation [ 12 ]. (biomedcentral.com)

page needed] Weight gain is associated with metabolic syndrome. (wikipedia.org)
However, despite the importance of obesity, affected people who are of normal weight may also be insulin-resistant and have the syndrome. (wikipedia.org)
The aim of the study is to investigate the efficacy and safety of TNX-1900 as a novel therapeutic agent to induce weight loss and improve indicators of cardiometabolic risk in adolescent patients with obesity. (tonixpharma.com)

India and many other countries in South-East Asia are currently going through the so-called nutrition transition which is associated with a change in the structure of the diet and rapid increase in the prevalence of obesity. (researchpaper.sbs)
Individuals in this study were born in four villages in El Progreso department in Guatemala from 1962 to 1977 and were participants in the Institute of Nutrition of Central America and Panama (INCAP) Nutrition Supplementation Trial Longitudinal Study cohort [ 19 ]. (biomedcentral.com)

Patients with cardiometabolic multimorbidity were at higher risk compared to patients with no cardiometabolic conditions ( adj OR 3.19 95%CI 1.61-6.34, p = 0.001). (biomedcentral.com)

Anatomy7

Organisms1

Diseases52

Chemicals and Drugs17

Analytical, Diagnostic and Therapeutic Techniques and Equipment39

Psychiatry and Psychology7

Phenomena and Processes31

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture1

Information Science3

Named Groups2

Health Care28

Geographicals10

Insulin resistance6

Disorders10

Hypertension6

Diabetes mellitus1

Prevalence of metabolic syndrome1

Dyslipidemia1

Diseases13

Type 2 diabet3

Components of metabolic syndrome1

Development of metabolic syndrome2

High-density lip2

Markers4

Obese3

Adipose tissue1

Outcomes4

Pathways4

Cardio-metabolic2

Epidemic1

Overweight5

Adults1

Adiposity1

Adolescents1

Childhood2

Abnormality1

Prediabetes1

Endocrine1

Health10

Inflammatory3

Cardiovascular risk1

Dysfunctional1

Elucidate1

Adult1

Coronary artery1

Imbalance1

Pathogenic1

Hormonal3

Glucose intolerance1

Protein2

Traits1

Mechanisms2

Subjects4

Adiponectin1

Alteration1

Complication1

Background1

Inflammation4

Weight3

Nutrition2

Conditions1