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  • residues
  • Mutation of LC3 residues predicted as cardiolipin-interaction sites by computational modelling inhibited its participation in mitophagy. (cdc.gov)
  • 2009), cardiolipin stabilizes the supercomplex formation by neutralizing the charges of lysine residues in the interaction domain of Complex III with Complex IV. (wikipedia.org)
  • found
  • The name 'cardiolipin' is derived from the fact that it was first found in animal hearts. (wikipedia.org)
  • We found that rotenone, staurosporine, 6-hydroxydopamine and other pro-mitophagy stimuli caused externalization of cardiolipin to the mitochondrial surface in primary cortical neurons and SH-SY5Y cells. (cdc.gov)
  • phosphate
  • Simultaneous quantification of cardiolipin, bis(monoacylglycero)phosphate and their precursors by hydrophilic interaction LC-MS/MS including correc. (nih.gov)
  • Damage
  • Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension. (lsbio.com)
  • We utilized two biologically relevant model systems, namely rotenone treatment of lymphocytes to induce mitochondrial damage and cell death as well as traumatic brain injury, to separate and identify cardiolipin oxidation products, critical to the cell death pathways in these tissues following cellular stress/injury. (cdc.gov)
  • contains
  • The envolope contains a variety of lipids including cardiolipins, phosphatidylglycerols, phosphatidylglycerophosphate methyl esters and phosphatidylglycerosulfates. (wikipedia.org)