• peroxidation
  • To quantitatively assess possible specific roles of peroxidation and hydrolysis of mitochondrial CL, we performed comparative studies of CL modifications using an animal model of Barth syndrome where deficiency of CL reacylation (Tafazzin [Taz] deficiency) was associated exclusively with the accumulation of mCLs (but not CLox). (jci.org)
  • integrity
  • By disrupting M-cadherin-dependent cell-cell adhesion by knocking down M-cadherin expression using RNA interference, we demonstrated that M-cadherin-mediated signaling is important for maintaining mitochondrial integrity. (biologists.org)
  • surface
  • We found that rotenone, staurosporine, 6-hydroxydopamine and other pro-mitophagy stimuli caused externalization of cardiolipin to the mitochondrial surface in primary cortical neurons and SH-SY5Y cells. (cdc.gov)
  • sites
  • Mutation of LC3 residues predicted as cardiolipin-interaction sites by computational modelling inhibited its participation in mitophagy. (cdc.gov)