Cardiac skeletal muscle stem cells clone cells. Medical search. Frequent questions

Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.com)
Immunoglobulin-related amyloidosis is a monoclonal plasma cell disorder in which the secreted monoclonal immunoglobulin protein forms insoluble fibrillar deposits in one or more organs. (medscape.com)
Before the discovery that the major fibril component in these patients was an immunoglobulin fragment, patients with light chain-type amyloidosis were described as having primary (in the sense of idiopathic) amyloidosis or, when the burden of monoclonal plasma cells was large, myeloma-associated amyloidosis. (medscape.com)
These monoclonal plasma cell disorders can be categorized according to the total body burden of monoclonal plasma cells. (medscape.com)
In most patients with a monoclonal plasma cell disorder, whether multiple myeloma or MGUS, the monoclonal L chain secreted by the clone remains soluble in the bloodstream. (medscape.com)
The relationship among light chain-type amyloidosis (AL), the other monoclonal plasma cell disorders, and the other amyloidoses. (medscape.com)

Moreover, miRNAs play a modulatory role in the development and growth of skeletal muscles [ 22 ]. (biomedcentral.com)

This instigated the search for cells that could differentiate into cells of the mesodermal tissue. (wikipedia.org)
This theory describes that mesoangioblasts act as the precursors to certain cells in this region, as there is a possibility of a hematopoiesis-supporting element that contains mesodermal tissue progenitors. (wikipedia.org)
Another prediction of mesoangioblast origin is that they may originate from post-natal bone marrow, which contains skeletal tissue progenitors that may be able to undergo myogenic differentiation. (wikipedia.org)
Both miRNAs and siRNAs need to be delivered into the target tissue or cell in order to activate the desired therapeutic effect," Muthiah Manoharan, Ph.D., senior vp, drug discovery, Alnylam Pharmaceuticals, explained. (genengnews.com)
Embryonic stem (ES) cells are derived from the embryo and are pluripotent, thus possessing the capability of developing into any organ, cell type or tissue type. (justia.com)
Methods of inducing differentiation in stem cells and muscle cells produced therefrom may be used for the study of cellular and molecular biology of tissue development, for the discovery of genes and proteins such as differentiation factors that play a role in tissue development and regeneration. (justia.com)
Ingestion of alcohol could act as a trigger by increasing the stress in heart tissue, leading to arrhythmia and cardiac arrest. (nature.com)
The heart is the first organ to form and has a complex structure consisting of many specialized cell types populating the heart muscle, blood vessels, and connective tissue. (tum.de)
As cells cultured in 2D fail to recapitulate certain features of their in vivo counterparts, part of our work is dedicated to developing 3D cardiac models that better mimic the physiology of heart tissue. (tum.de)
We routinely produce engineered heart tissue based on hiPSC-derived cardiac cells seeded on decellularized ventricular matrix from pigs or non-human primates, which we cultivate in a biomimetic chamber system promoting tissue maturation by continuous mechanical and electrical stimulation. (tum.de)
Adipose tissue is a loose connective tissue composed of cells supported by an intracellular matrix as well as by vascular, lymphatic, and neural networks. (jcadonline.com)
Thus, it has been shown that early EPCs release cytokines that promote tissue regeneration and neovasculogenesis, whereas late EPC and endothelial colony forming cells (ECFCs) contribute to the formation of blood vessels and stimulate tube formation. (intechopen.com)

From these findings, researchers concluded that the donor cells are involved with the developing mesoderm and vasculature of host tissues. (wikipedia.org)
They are also characterized by their ability to migrate and integrate into damaged tissues and their capabilities of self-renewal, which allows them to maintain their stem cell properties over multiple passages. (wikipedia.org)
CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. (thermofisher.com)
It has been found that some of the SVF cell types possess regenerative and anti-inflammatory potentials in damaged tissues due to their ability to secrete growth factors and anti-inflammatory molecules. (jcadonline.com)
Her work on the T cell tyrosine kinase ITK has revealed a critical role for this TCR signaling protein in autoreactive T cell trafficking into tissues such as the pancreas and the intestine. (cuanschutz.edu)
The expression level of the SFRP1 was highly varied across numerous pig tissues and it was down-regulated during porcine skeletal muscle development. (biomedcentral.com)
Increased curiosity about CAPN3 was highly stimulated when it had been reported that mutations in its gene bring about limb-girdle muscular dystrophy (LGMD) type 2A, seen as a the continuous atrophy of hip and make muscle tissues (LGMD2A, or calpainopathy) (21). (exposed-skin-care.net)
hEPCs have been used for cell-based therapies due to their capacity to contribute in the re-endothelialization of injured blood vessels and neovascularization in ischemic tissues. (intechopen.com)

human pluripotent stem cell (hPSC)-derived myoblasts may be cultured on cultureware coated with Corning® Matrigel® hESC-Qualified Matrix. (stemcell.com)
Due to their limited fates, they would not be considered pluripotent stem cells, but they still provide a significant number of differentiation paths that can be used for a wide variety of applications. (wikipedia.org)
Whilst differentiation of some lineage specific stem cells can be induced with a degree of certainty, a differentiation outcome of a population of pluripotent stem cells is less predictable. (justia.com)
The study was a proof of concept, and used induced pluripotent stem cells (iPSCs). (singularityhub.com)
In the research projects outlined below, we combine 2D and 3D in vitro models based on human pluripotent stem cells with animal models such as the mouse and pig. (tum.de)
Human induced pluripotent stem cells (hiPSCs) are stem cells that are derived from the somatic cells (e.g. blood or skin cells) of healthy individuals or patients. (tum.de)

Ensure high yields when passaging and culturing your primary human skeletal muscle progenitor cells (myoblasts) by using MyoCult™-SF Attachment Substrate, which is optimized to support myoblast attachment. (stemcell.com)
The EasySep™ Human CD56 Positive Selection Kit II is designed to isolate CD56+ cells from fresh or previously frozen peripheral blood mononuclear cells and human skeletal muscle (myoblasts and fibroblasts) cultures by positive selection. (stemcell.com)

In iron-depleted cells, the proteins bind to RNA stem-loops in transcripts known as iron-responsive elements (IRE). (nih.gov)
Confocal immunofluorescence image of hiPSC-derived cardiomyocytes stained for the sarcomere proteins cardiac troponin T (red) and a -actinin (green). (tum.de)
The focus of Dr. Berg's work is on the signaling proteins and pathways regulating T lymphocyte development, differentiation, activation, and migration, with a strong emphasis on T-cell receptor (TCR) signaling. (cuanschutz.edu)

At this stage, the dorsal aorta consists mainly of an endothelial layer with a few mesenchymal cells on the abluminal side. (wikipedia.org)

Recent advances in developmental and stem cell biology have paved the way for a wide spectrum of novel cardiovascular therapies, from the transplantation of stem cell-derived cells to the stimulation of endogenous regeneration processes. (tum.de)
These cells can be differentiated into mature endothelial cells, which are involved in processes of angiogenesis and vessel regeneration. (intechopen.com)

Notch 1 is expressed on thymocytes, bone marrow hematopoietic stem cells, T and NK cells. (thermofisher.com)

Lack of FKBP12 is known to result in lethal cardiac dysfunction in mouse. (biomedcentral.com)
Many studies implicate mitochondrial dysfunction as a key contributor to cell loss in Parkinson disease (PD). (nature.com)

The first stem cells were removed from spare embryos at fertility clinics in 1998 and a human embryonic stem cell line was set up on a permanent basis. (uofe.org)

The present invention relates to methods of inducing differentiation of stem cells. (justia.com)
In particular, the invention relates to methods of inducing differentiation of embryonic stem cells into muscle cells or vascular endothelial cells. (justia.com)
The process of differentiation in stem cells involves selective development of immature cells to committed and fully mature cells of various lineages. (justia.com)
Differentiation of stem cells is known be triggered by various growth factors and regulatory molecules. (justia.com)
During differentiation the expression of stem cell specific genes and markers are often lost and cells acquire gene expression profiles of somatic cells or their precursors. (justia.com)
Placing the cells under conditions which induce specific cell types has been one form of an attempt to regulate the differentiation outcome. (justia.com)
These conditions include growing the cells to high or low density, changing media, introducing or removing cytokines, hormones and growth factors, creating an environment which suits differentiation toward a specific cell type, such as providing a suitable substrate. (justia.com)
The induction of cardiomyocyte differentiation in stem cells is especially useful in developing therapeutic methods and products for heart disease and abnormal heart conditions. (justia.com)
However, the molecular pathways that lead to specification and terminal differentiation of specific cell types, such as myocytes, from embryonic stem cells during development are not entirely clear. (justia.com)
Therefore there remains a need for providing effective methods of inducing differentiation of stem cells into specific cell types, such as myocytes or endothelial cells. (justia.com)
culturing a stem cell in the presence of an embryonic cell and/or extracellular medium of an embryonic cell, under conditions that induce differentiation of the stem cell. (justia.com)
This cell surface receptor is involved in T cell lineage commitment, thymocyte development, and Th2 differentiation. (thermofisher.com)
The Wnt signaling pathway is involved in the control of cell proliferation and differentiation during skeletal muscle development. (biomedcentral.com)
The power of the thiol proteinases to cleave a multitude of substrates in response to calcium mineral activation allows their involvement in a variety of cell processes offering cell motility, sign transduction, apoptosis, cell differentiation and legislation of the cytoskeleton (3). (exposed-skin-care.net)

Does not cross-react with adult cardiac, smooth, or skeletal muscle actin. (abcam.com)

who found that a skeletal muscle precursor could be found in postnatal mice bone marrow. (wikipedia.org)
Aorta-derived cells also differentiated into chondrocytes, smooth muscle cells, and bone cells. (wikipedia.org)
Adult stem cells are immature cells found in bone marrow and other organs in adult human beings, as well as umbilical cords normally discarded at birth. (uofe.org)
Lupus patients treated with stem cells from their own bone marrow have exceeded expectation. (uofe.org)
Cardiac function is believed to be improved in heart arteries that have been injected with adult bone marrow stem cells. (uofe.org)
In some studies leukemia patients treated with stem cells from bone marrow and umbilical cord blood became free of disease (as noted above). (uofe.org)
Prophylaxis against bone loss should be given to all transplant recipients, regardless of baseline skeletal reserve. (medscape.com)
Regular weight-bearing and muscle-strengthening exercises are recommended to improve bone strength and reduce the risk of fracture. (medscape.com)
Skeletal phenotyping, such as measuring bone mineral density (BMD) and histomorphometry analysis with bone biopsy, has provided an explanation, in part, of the elevated fracture risk. (medscape.com)
6,7 Mesenchymal stem cells (MSCs) have also been isolated from other sources, such as bone marrow, 8 the placenta, 9 muscle, 10 or blood. (jcadonline.com)
Human endothelial progenitor cells (hEPCs) are adult stem cells, located in the bone marrow and peripheral blood. (intechopen.com)

Quail donor cells colonized the vascular walls of chick wings, being especially prominent in skeletal muscle. (wikipedia.org)
however, a variety of other cell types are found as well, collectively labeled as stromal vascular fraction (SVF). (jcadonline.com)

Applications Tested: This APB5 antibody has been tested by flow cytometric analysis of NIH/3T3 cells. (thermofisher.com)
A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. (thermofisher.com)
This antibody clone [mAbcam 8226] is manufactured by Abcam. (abcam.com)
FACS analysis of positive PEER cells (left and middle panel) or negative control Jurkat cells (right panel) using GTX79232 TCR V delta 1 antibody [TS8.2]. (genetex.com)
ICC/IF analysis of HepG2 cells using GTX15746 Ferritin antibody [101]. (genetex.com)
Cells were probed without (left) or with(right) an antibody. (genetex.com)
Applications Tested: This MHN1-519 antibody has been pre-titrated and tested by flow cytometric analysis of normal peripheral blood cells. (thermofisher.com)

Nine boys aged 6 to 12 who have been living with DMD since birth received a gene therapy treatment from pharmaceutical giant Pfizer, and a year later, 7 of the boys show significant improvement in muscle strength and function. (singularityhub.com)
It's caused by mutations in the gene that makes dystrophin, a protein that serves to rebuild and strengthen muscle fibers in skeletal and cardiac muscles. (singularityhub.com)
As a grad student in 1984, Samulski was part of the first team to clone an adeno-associated virus, which ended up becoming a leading method of gene delivery and thus crucial to gene therapy. (singularityhub.com)
the virus was injected into boys with DMD, broke into their muscle cells, and replaced their non-working gene. (singularityhub.com)
Gene therapy trials are underway for several different genetic diseases, including sickle cell anemia , at least two different forms of inherited blindness , and Alzheimer's , among others. (singularityhub.com)
The role of pyrophosphatase 2 (PPA2) in mitochondrial disease has recently emerged with the discovery of biallelic PPA2 variants that cause a partial loss of gene function (hypomorphs) within families affected by recurrent sudden cardiac death in siblings. (nature.com)
Another important facet of our work is the use of CRISPR/Cas9 gene editing for many applications including the generation of reporter cell lines and the design of novel gene therapy approaches. (tum.de)
We demonstrate that deletion of ERRγ from DAergic neurons in adult mice was sufficient to cause a levodopa-responsive PD-like phenotype with reductions in mitochondrial gene expression and number, that partial deficiency of ERRγ hastens synuclein-mediated toxicity, and that ERRγ overexpression reduces inclusion load and delays synuclein-mediated cell loss. (nature.com)
Silver nanoparticles administered to chicken affect VEGFA and FGF2 gene expression in breast muscle and heart. (cloud-clone.com)
Studies show that some subsets of T-cell acute lymphoblastic leukemia (T-ALL) arise due to Notch1 chromosomal translocation with the TCRbeta gene, which results in the expression of constitutively active Notch1. (thermofisher.com)
The miRNA-mRNA profiles and bioinformatics study suggested that the SFRP1 gene was potentially regulated by miRNA-1/206 during porcine skeletal muscle development. (biomedcentral.com)
Our results indicate that the SFRP1 gene is regulated by miR-1/206 and potentially affects skeletal muscle development. (biomedcentral.com)
As opposed to other styles of muscles dystrophy, where mutations take place in genes encoding structural protein, calpainopathy was the initial reported kind of dystrophy predetermined by mutations within a gene encoding a proteolytic enzyme. (exposed-skin-care.net)
Clonal plasma cell proliferative diseases in which the Vl 6 gene is expressed are always associated with amyloid deposition. (medscape.com)

cloned murine embryonic organs and, after analysis, found cells in the dorsal aorta clones that were able to differentiate into skeletal myogenic progenitors that expressed myogenic markers like MyoD, Myf-5, and desmin. (wikipedia.org)
However, the roof and lateral walls of the dorsal aorta known to have cells that can differentiate into muscle cells or even more cell types, otherwise known as bona fide mesoangioblasts. (wikipedia.org)
Mesoangioblasts have the ability to differentiate into multiple cell types, such as skeletal muscle, smooth muscle, and endothelial cells. (wikipedia.org)
This allows them to maintain a population of stem cells that can differentiate into the aforementioned cell types. (wikipedia.org)
Generally, when a stem cell culture is induced to differentiate, the differentiated population is analysed for particular cell types by expression of genes, markers or phenotypic analysis. (justia.com)
In particular, the induction of stem cells to differentiate into muscle cells (myocytes) is useful for muscle transplantation and therapeutic purposes, as well as providing potential human disease models in culture (e.g. for testing pharmaceuticals). (justia.com)
During early cardiac development, cells must multiply rapidly but also specify, i.e. limit their developmental potential and determine into which cell type they will later differentiate. (tum.de)
Our group investigates how different cardiovascular progenitor populations arise, specify, and differentiate, notably by dissecting lineage trajectories via single-cell transcriptomics and chromatin accessibility profiling. (tum.de)
Intradermal adipocyte progenitor cells are activated toward the end of the telogen phase to proliferate and differentiate into mature adipocytes. (jcadonline.com)

Live immunofluorescence imaging of a 3D cardiac spheroid derived from a double reporter stem cell line expressing eGFP and mCherry in the endogenous loci of the cardiac transcription factors NKX2.5 and TBX5 , respectively. (tum.de)

To take human organ generation via BC and transplantation to the next step, we reviewed current emerging organ generation technologies and the associated efficiency of chimera formation in human cells from the standpoint of developmental biology. (frontiersin.org)

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). (genetex.com)
The discovery and characterization of new antigens implicated in the pathogenesis of T1D is a high priority as it can lead to new diagnostic tools and anticipate that studies proposed by Dr. Baker will provide critical information to target autoreactive T cells though antigen-specific therapies. (cuanschutz.edu)

In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. (genetex.com)
If not, the cell proceeds to rearrange the beta and alpha loci. (genetex.com)
This region represents the germline organization of the T cell receptor alpha and delta loci. (genetex.com)
Ectopic expression in mouse cells and CRISPR/Cas9 base editing of endogenous AGS loci revealed causal roles of one AGS-specific amino acid substitution in mediating cytoprotection by AGS ATP5G1. (elifesciences.org)

In insect, Drosophila melanogaster ryanodine receptor ( DmRyR ) cDNA was cloned from lava and the physical features of DmRyR single channel were characterized with in vitro overexpression system [ 16 ]. (biomedcentral.com)
Through cell survival-based cDNA expression screens in neural progenitor cells, we identify a genetic variant of AGS Atp5g1 that confers cell resilience to metabolic stress. (elifesciences.org)

Normal human peripheral blood cells were either unstimulated (blue histogram) or stimulated with immobilized Anti-Human CD3 Functional Grade Purified (Product # 16-0039-81) for 24 hours (purple histogram) and then stained with Anti-Human Notch1 APC. (thermofisher.com)

When these cells were combined with satellite cells from wt P10 mice and cultured, the two cell types were able to coalesce and regenerate skeletal muscle in vivo. (wikipedia.org)
We have also established an ex vivo embryo culture system that allows us to study the function of human cardiac cells in human-mouse or human-pig chimeras. (tum.de)

For more information on protocols for the derivation and expansion of human skeletal muscle progenitor cells with MyoCult™, please explore the Product Information Sheet . (stemcell.com)
Like other viruses, AAVs can break through cells' outer membranes-especially eye and muscle cells-get inside, and "infect" them (and their human hosts). (singularityhub.com)
You can see how many people began to react and to wonder if this would result in human cloning factories and embryo farms to cultivate human spare parts. (uofe.org)
Injecting stem cells into a human patient entails the same problem as other types of transplants: rejection of the foreign cells by the person's immune system. (uofe.org)
They have the capacity to self-renew indefinitely and to give rise to any cell type of the body in vitro , making them an exceptionally powerful tool for studying human disease in patient-specific backgrounds. (tum.de)
Initial, CAPN3 is AZ-33 normally mostly muscle-specific (9), but is normally detectable in zoom lens, liver, human brain and cardiac muscles during advancement (10C13). (exposed-skin-care.net)

The present invention also provides methods of using the differentiated cells of the present invention for therapeutic purposes. (justia.com)
Therapeutic cloning, which we discussed in Section 1, and which is one of the two sources of embryonic stem cells (ES), has brought to the center of the debate the issues of "humanness" and the legal status of an embryo: these are areas involving great controversy and discussion involving ethics, morality, and philosophy. (uofe.org)
Once a therapeutic target has been identified, we also use hiPSC-derived cells as a platform for testing novel therapies, as we have previously done for Duchenne muscular dystrophy (DMD). (tum.de)

A mesoangioblast is a type of progenitor cell that is associated with vasculature walls. (wikipedia.org)

Research has suggested their application for stem cell therapies for muscular dystrophy and cardiovascular disease. (wikipedia.org)

Many anti-abortionists and evangelical Christians argued that adult stem cells (AS) could be used to provide the same results. (uofe.org)
Proponents of using embryonic stem cells counter that adult stem cells, while useful fo some diseases, don't produce the expanded range of cell types possible from embryonic stem cells. (uofe.org)
This is why adult stem cells are so valuable: great potential without the problem of ethics. (uofe.org)
Adult stem cells may be helpful in repairing eroded cartilage. (uofe.org)

Role of glycosphingolipid SSEA-3 and FGF2 in the stemness and lineage commitment of multilineage differentiating stress enduring (MUSE) cells. (nih.gov)

Mesoangioblasts were identified based on their unique cell surface marker profile, which includes the expression of endothelial cell markers like KDR and angiopoietic cell markers like FLK1. (wikipedia.org)

These cells also expressed endothelial markers like VE-cadherin, VEGF-R2, and β3 integrin. (wikipedia.org)

Discovery of iron-sulfur cofactors will lead to breakthroughs in several research areas involving DNA repair, ribosomal biogenesis, mRNA translation, intermediary metabolism, and regulation of the growth and energy-sensing pathways that are critical for determining the fates of many cell types. (nih.gov)

Mesoangioblasts are multipotent stem cells with the potential to progress down the endothelial or mesodermal lineages. (wikipedia.org)

PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. (thermofisher.com)

Immunoreceptor signaling during development, homeostasis, and effector function of T cells and NK cells. (upstate.edu)
His work has ranged from exploring the mechanisms contributing to T cell effector function to investigating the role of new beta-cell autoantigens. (cuanschutz.edu)

While the extracellular domain contains numerous epidermal growth factor-like repeats for ligand binding, the intracellular domain is involved in cell signaling. (thermofisher.com)

IREs are RNA stem-loops found in the 5′ end of ferritin mRNA and the 3′ end of transferrin receptor mRNA. (nih.gov)
Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. (genetex.com)

Dual luciferase assay and Western-blot results demonstrated that SFRP1 was a target of miR-1/206 in porcine iliac endothelial cells. (biomedcentral.com)

These cells, surrounding the hair follicles, secrete signaling molecules that control the progression of the hair cycle. (jcadonline.com)

The induction of a specific differentiated cell type can be useful for transplantation or drug screening and drug discovery in vitro. (justia.com)

Within these 28 cases, 15 died of sudden cardiac arrest and 13 of acute heart failure. (nature.com)
The spectrum of clinical presentations included sudden unexpected death in children before the age of 2 years, mitochondrial disease leading to death in infants aged between 1 month and 2 years, sudden cardiac arrest following the ingestion of small amounts of alcohol in teenagers, and adults reporting acute sensitivity to alcohol. (nature.com)

The expression level of the SFRP1 was significantly higher in the embryonic skeletal compared with postnatal skeletal muscle, whereas miR-206 showed the inverse pattern of expression. (biomedcentral.com)

In addition to basic science investigations in such areas as tumor cell invasion, oncogenes, immunotherapy and genetic inheritance, our scientists and physicians participate in national cancer trials. (upstate.edu)
While immune checkpoint inhibitors are very effective in cancer treatment, their effect is not only limited to tumor cell and they have many autoimmune side effects. (cuanschutz.edu)

However, though BC is emerging as a potential organ transplant option, challenges regarding organ size scalability, immune system incompatibilities, long-term maintenance, potential evolutionary distance, or unveiled mechanisms between donor and host cells remain. (frontiersin.org)

The invention also includes cells, cell lines, testing models and culture systems used in the methods of the present invention and differentiated cells produced therefrom. (justia.com)

Stem cells are undifferentiated cells which can give rise to a succession of mature functional cells. (justia.com)
If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. (genetex.com)
A major focus has been understanding the role of intra-islet communication and functional sub-populations of cells in islet function, and how disruption to intra-islet communication mechanisms and changes in sub-populations occur in diabetes and may contribute to islet decline. (cuanschutz.edu)

The muscle cells already lost to DMD won't "grow back," but the treatment appears to have restored normal function of the protein that fixes muscle fibers and helps them grow, meaning no further degeneration should take place. (singularityhub.com)
IRP1 is an iron-sulfur protein that functions as an aconitase in iron-replete cells. (nih.gov)
Biallelic hypomorphic variants in PPA2 , encoding the mitochondrial inorganic pyrophosphatase 2 protein, have been recently identified in individuals presenting with sudden cardiac death, occasionally triggered by alcohol intake or a viral infection. (nature.com)
Examining the genetic code of these resilient cells revealed that Arctic ground squirrels may have a variant form of a protein called ATP5G1. (elifesciences.org)
This protein is found in a cellular compartment called the mitochondria, which is responsible for supplying energy to the rest of the cell and therefore plays an important role in metabolic processes. (elifesciences.org)
These findings provide the first evidence of a protein variant that is responsible for protecting cells during the metabolic stress conditions caused by hibernation. (elifesciences.org)

Outlining the physiological responses at the cellular level,Flück goes on to describe the characterisation of these responses to repeated short bouts of training over several weeks, as well as discussing stimuli, such as hypoxia, that may trigger metabolic adjustments in muscles in response to exercise. (silverchair.com)
Although hypoxic or ischemia tolerance in AGS involves physiological adaptations, little is known about the critical cellular mechanisms underlying intrinsic AGS cell resilience to metabolic stress. (elifesciences.org)
But, it is unclear how their cells are able to endure this metabolic stress. (elifesciences.org)
In addition, the number and the migratory activity of these cells are inversely correlated with risk factors such as hypertension, hypercholesterolemia, diabetes, and metabolic syndrome. (intechopen.com)
Cell-free metabolic engineering: production of electrobiofuels. (kameshwarmahadev.com)

CAPN3 is normally a component from the skeletal muscles triad, in charge of calcium release. (exposed-skin-care.net)

At birth, some affected newborns may have a minor skeletal phenotype, such as humpback, chest protrusion, and prominent forehead, as confirmed with radiography. (medscape.com)

Following on from Flück's overview of plasticity in mammalian muscle,Ian Johnston considers fish muscle and environmental effects during development. (silverchair.com)
Johnston ( p. 2249 ) describes how plasticity in the early stages of muscle development tends to be irreversible as larval development is so rapid. (silverchair.com)
For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. (rndsystems.com)

Anatomy47

Organisms8

Diseases8

Chemicals and Drugs24

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Phenomena and Processes31

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena1

Information Science3

Monoclonal6

Growth of skeletal1

Tissue12

Tissues8

Pluripotent6

Myoblasts2

Proteins3

Mesenchymal cells1

Regeneration2

Hematopoietic stem1

Dysfunction2

Embryonic stem1

Differentiation14

Actin1

Bone11

Vascular2

Antibody7

Gene14

Differentiate9

NKX2.51

Biology1

Antigen2

Loci4

CDNA2

Peripheral1

Vivo2

Human6

Therapeutic3

Progenitor cell1

Therapies1

Adult stem4

Lineage1

Endothelial cell1

Integrin1

Metabolism1

Multipotent1

Tyrosine kinase1

Effector function2

Intracellular1

Receptor2

Porcine1

Molecules1

Transplantation1

Acute2

Postnatal1

Tumor cell2

Organ1

Methods1

Functional3

Protein6

Metabolic5

Calcium1

Prominent1

Development3