• This study provides novel evidence for widespread alterations in DNA methylation during postnatal heart maturation and suggests that cardiomyocyte cell cycle arrest during the neonatal period is subject to regulation by DNA methylation. (nih.gov)
  • Interest in ALMS1 is heightened by the recent discovery of its involvement in neonatal cardiomyocyte cell cycle arrest, a process with potential relevance to regenerative medicine. (springer.com)
  • Mechanisms regulating cardiomyocyte cell cycle arrest are of great interest partly because reversing this process could provide a way to stimulate cardiac regeneration after injury [ 17 ]. (springer.com)
  • OBJECTIVE: This study is designed to evaluate the efficacy and safety of CDDP in improving ventricular remodeling and cardiac function after AAMI on a larger scale. (bvsalud.org)
  • By employing microRNA expression profiling and functional knockdown studies on human embryonic stem cell-derived cardiomyocytes, the authors identified miR-363 as an upstream negative regulator of left ventricular specification transcription factor HAND1 . (biomedcentral.com)
  • The recent publication by Wagh and colleagues sought to identify the novel miRNAs regulating cardiac-specific transcription factors that determine left versus right ventricular determination [ 1 ]. (biomedcentral.com)
  • After 48 hours of exposure, these mice showed persistent cardiac inflammation and oxidative tissue damage that caused sarcomeric disruption, cardiomyocyte death, left ventricular dysfunction, and cardiomyopathy, while control hearts showed minimal damage. (jci.org)
  • Indeed, even sublethal mitochondrial damage can impair cardiac ATP provision and ventricular contraction. (jci.org)
  • The main inherited cardiac arrhythmias are long QT syndrome, short QT syndrome, catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome. (cdc.gov)
  • Both pharmacological inhibition or genetic deletion of CHK1 and administration of gemcitabine induced mtROS overproduction and pyroptosis in cardiomyocytes by disrupting mitochondrial respiration, ultimately causing heart atrophy and cardiac dysfunction in mice. (bvsalud.org)
  • Further hiPSC-CMs and mice experiments demonstrated that SIRT3 overexpression maintained mitochondrial function while alleviating CM pyroptosis, and thereby improving mice cardiac function. (bvsalud.org)
  • Mouse endometrial epithelial cells (MEECs) were isolated from C57BL female mice, and long-term cultures of MEECs were established and maintained with conditional reprogramming (CR) method. (biomedcentral.com)
  • For example, multiple cycles of fasting combined with chemotherapy cured 20 percent of mice with a highly aggressive type of children's cancer that had spread throughout the organism and 40 percent of mice with a more limited spread of the same cancer. (sciencedaily.com)
  • In mice, the study found that fasting cycles without chemotherapy could slow the growth of breast cancer, melanoma, glioma and human neuroblastoma. (sciencedaily.com)
  • The tubule cell damage and cell death that characterize ATN usually result from an acute ischemic or toxic event. (medscape.com)
  • Reliable markers for impending acute kidney injury in ADHF constitute an unmet need, with candidates, such as kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin, failing to perform sufficiently well, and new possibilities, including the cell cycle markers insulin growth factor binding protein 7 and tissue inhibitor of metalloproteinases type 2, remain the subject of research. (cfrjournal.com)
  • Acute kidney injury (hereinafter "AKI") is an unfortunately common complication of cardiac surgery that occurs in up to 40% of patients and results in increased mortality, prolonged intensive care unit stays, and prolonged hospital stays. (justia.com)
  • Accordingly, the inherent time lags in measuring serum creatinine and the uncertainties in measuring urinary output render the measurements insensitive to acute changes in renal function and relatively useless in the prevention of AKI during and after cardiac surgery. (justia.com)
  • Venetoclax is active in other lymphoid malignancies including several B cell non-Hodgkin lymphomas, acute lymphoblastic leukemia and multiple myeloma, with the highest intrinsic sensitivity observed in mantle cell lymphoma and Waldenstrom macroglobulinemia. (biomedcentral.com)
  • His workup showed a low blood cell count and signs of acute kidney injury. (cdc.gov)
  • One 2013 study on 107 cases of sudden cardiac arrest found only 20.5 percent of footballers survived and with a little more than half having an on-site defibrillator-a device that shocks the heart to restore a normal heartbeat. (popsci.com)
  • Heart attacks, a common cause of sudden cardiac arrest , obstruct blood flow to the heart. (popsci.com)
  • These rare diseases are often the underlying cause of sudden cardiac death in young individuals and result from mutations in several genes encoding ion channels or proteins involved in their regulation. (cdc.gov)
  • There is the incidence of sudden cardiac death syndrome, which can affect athletes.¹ A study done in 1994, the subjects of which were fit, healthy and well conditioned young men, showed that strenuous and continuous effort affected Mg levels. (magnesiumandhealth.com)
  • Protective hypothermia is mainly used for the treatment of neonatal encephalopathy, cardiac arrest, neurogenic fever, and more recently brain and spinal cord trauma. (ajnr.org)
  • Several of these biomarkers have been used for the early prediction of AKI in cardiac surgery patients. (justia.com)
  • Venetoclax combination with standard regimens in follicular lymphoma, multiple myeloma and aggressive B cell neoplasms has shown some promise, but further studies are required to optimize dose and scheduling to mitigate increased myelosuppression and infection risk, and to find validated biomarkers of venetoclax sensitivity. (biomedcentral.com)
  • During myocardium infarction or heart failure, the extensive loss of CMs leads to progressive cardiac dysfunction and chronic heart failure, a leading cause of morbidity and mortality in the developed world. (biomedcentral.com)
  • Mitochondrial function or the ability to generate energy through OXPHOS (oxidative phosphorylation) is vital for cell homeostasis and its dysfunction has been linked to the pathogenesis of nearly all chronic diseases ( Pieczenik and Neustadt, 2007 ). (frontiersin.org)
  • The administration of bone marrow-derived mesenchymal stem cells (BMSCs) is emerging as a promising approach for I/R injury-induced myocardial infarction due to its multiple differentiation potential(7, 8). (researchsquare.com)
  • MicroRNAs regulate target gene expression post-transcriptionally in a myriad of cell types and play critical roles in diverse physiological and pathological processes, including cardiomyocyte development, differentiation, and regeneration. (biomedcentral.com)
  • Such a prospect is currently hampered, however, in part by an incompletely defined complex of molecular regulators of cardiac cell development and differentiation. (biomedcentral.com)
  • This commentary discusses the findings from Wagh and colleagues published in this issue of Stem Cell Research and Therapy demonstrating a critical role for miR-363 in post-transcriptional regulation of CM differentiation via the hand and neural crest derivative expressed HAND1 transcription factor [ 1 ]. (biomedcentral.com)
  • Identifying molecular regulators and critical mediators of cardiac cell type development, proliferation, and differentiation is of great clinical importance, and unraveling such molecular horizons could lead to the development of therapeutic strategies for successful regeneration of the human adult heart. (biomedcentral.com)
  • miRNAs could thus be the best targets for understanding cardiac specialization during differentiation of human embryonic stem cells (hESCs). (biomedcentral.com)
  • The cycle is then completed with a T wave that corresponds to electrical repolarization of the ventricles before the next heartbeat. (athletesheart.org)
  • CARDIAC CYCLE (ONE HEARTBEAT, PULSE 75) The outer circle represents the ventricles, the middle circle the atria, and the inner circle the movement of blood and its effect on the heart valves. (unboundmedicine.com)
  • This is a rare situation where a strike to the chest occurs during a certain point in the heartbeat cycle. (popsci.com)
  • The heartbeat cycle consists of different electrical waves that mechanically stimulate the heart. (popsci.com)
  • Hmox1 ) enzyme system is among the most important inducible mechanisms for cell protection against oxidative damage in the cardiovascular system. (jci.org)
  • Conditionally reprogrammed physiological endometrial epithelial cells provide a novel strategy in IUA clinics in a personalized or generalized manner and also serve as a physiological model to explore biology of endometrial epithelial cells and mechanisms of IUA. (biomedcentral.com)
  • This seminal observation instigated the ensuing decades of research that characterized the complex mechanisms of intrinsic cell death and lay the foundations for the development of therapeutics capable of restoring apoptosis in malignant cells. (biomedcentral.com)
  • MSCs can promote host tissue repair through several different mechanisms including donor cell engraftment, release of cell signaling factors, and the transfer of healthy organelles to the host. (frontiersin.org)
  • In the cerebellum, the Purkinje cells are especially sensitive to heat, and patients with hyperthermia may later develop chronic cerebellar atrophy. (ajnr.org)
  • Infants suffering of cell death occurring as a series of changes from chronic illnesses, chromosomal abnor- in dying cells under several physiological malities and those on medication prior to conditions [ 6,7 ] and has been implicated enrolment were excluded from the study. (who.int)
  • CONTEXT: Waterpipe tobacco smoking (WTS) has gained popularity, but its physiologic effects have not been extensively studied: rather, studies have focused on WTS's chronic effects or have evaluated limited respiratory/cardiac parameters. (who.int)
  • 1,2 This brief review will summarise the main evidence underpinning this status and also outline the shortcomings of B-type cardiac peptides as diagnostic aids in ADHF. (cfrjournal.com)
  • These protective effects may be associated with the inhibition of apoptosis and inflammation, as reflected by less TUNEL-positive cells and lower levels of serum proinflammatory cytokines (Interleukin-1β, Interleukin-6, tumor necrosis factor-α) and cardiac troponin I in the N-CM group compared with the vehicle group. (researchsquare.com)
  • The tumor is ablated using small high-voltage pulses that induce slow cell death over time. (hfma.org)
  • The advantages of this type of ablation are it is very tissue selective, only destroying the cancer cells and preserving the vital structures that surround the tumor, and it is also very quick. (hfma.org)
  • The growth of large tumor masses was reduced by multiple fasting and chemotherapy cycles, but cancer-free survival could not be achieved. (sciencedaily.com)
  • Longo speculated that cells inside a large tumor may be protected in some way or that the variety of mutations in a large mass may make it more adaptable. (sciencedaily.com)
  • In addition, cardiac markers of aging-induced damage, including radical oxidative species levels, mitochondrial metabolic activity, mitochondrial calcium buffer capacity, and estrogenic signaling functions, were also modulated by the compound. (hindawi.com)
  • In addition, some pathways that are typically altered during cardiac aging-induced damage, including the generation of radical oxidative species, the mitochondrial metabolic activity, the modulation of the mitochondrial calcium buffering capacity, and the regulation of estradiol and estrogen-regulated gene expression, were investigated [ 20 - 22 ]. (hindawi.com)
  • Lower temperatures inhibit the influx of ions (noticeably calcium) into cells, avoid oxidative stress, decrease free radical production, and, finally, prevent apoptosis. (ajnr.org)
  • The efficient derivation of specialized and functional cardiomyocytes (CMs) from pluripotent stem cells is a primary goal for stem cell-based cardiac regenerative therapies. (biomedcentral.com)
  • It is also responsible for inhibition of vascular endothelial growth factors receptors, plateletderived growth factor receptors, and stem cell factor receptor [ 8 , 9 ]. (hindawi.com)
  • Only some cells have testosterone receptors, and therefore only those cells. (parklandsbeachvolleyball.com)
  • They both share many features such as cell wall receptors. (parklandsbeachvolleyball.com)
  • As a medication, it is used to treat several conditions, including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. (wikipedia.org)
  • The arrest of bleeding in a superficial wound, such as the bleeding time wound, almost exclusively results from the primary hemostatic plug. (medscape.com)
  • The aim of this paper is to analyse sunitinib malate in vitro ability to enhance cisplatin cytotoxicity in T24, 5637, and HT1376 human urinary bladder-cancer cell lines. (hindawi.com)
  • This investigation aims to analyse the in vitro effects of cisplatin and sunitinib malate in isolation and in combination, on one human nonmuscle invasive urinary bladder-cancer cell line (5637) and on two human muscle-invasive urinary bladder-cancer cell lines (T24 and HT1376). (hindawi.com)
  • Employing in vitro cell culture of inherited mitochondrial disease and an in vivo animal experimental model of low-grade inflammation (high fat feeding), we show human-derived MSCs to alter mitochondrial function. (frontiersin.org)
  • Most of the metabolic energy of neurons is expended on maintaining ion gradients across the cell membrane. (benbest.com)
  • In times of high metabolic demand and adequate availability of oxygen, elevated calcium in mitochondria can increase ATP production by stimulation of three enzymes in the Krebs citric acid cycle: pyruvate dehydrogenase, alpha-ketoglutarate and isocitrate dehydrogenase. (benbest.com)
  • Potassium ions rush out of the cell while sodium & chloride ions rush inward as the cell membranes depolarize. (benbest.com)
  • Potassium ATP (Krebs Cycle… Aaaah! (fdocuments.net)
  • Drives the potassium into the cell. (fdocuments.net)
  • Global cerebral ischemia/reperfusion injury (GCIRI) occurs in patients who are successfully resuscitated from various clinical conditions such as cardiac arrest, asphyxia and shock, which are frequently accompanied by inflammation and can lead to serious neuronal injury, and further to neurodegeneration and learning and memory impairment [ 12 ]. (biomedcentral.com)
  • Patients should have an ophthalmic examination (including visual acuity and slit lamp examination) performed by an eye care professional at baseline, before the subsequent 3 treatment cycles, and as clinically indicated whilst on treatment (see section 4.4). (medicines.org.uk)
  • Various cellular senescence hallmarks (the percentage of X-gal staining cells, the mRNA levels of the p16 and p21 cell cycle regulators, and the percentage of cell cycle-arrested cells) were investigated. (hindawi.com)
  • BCL2 and other components of the intrinsic cell death pathway are critical regulators of cell survival, frequently perturbed by cancer cells resulting in evasion of programmed cell death [ 1 ]. (biomedcentral.com)
  • Recently, miRNAs have been recognized as important players in cardiac development, pathology, and regeneration. (biomedcentral.com)
  • Bone marrow mesenchymal stem cells (BMSCs) have been reported to attenuate myocardial I/R injury via their paracrine effects, which can be enhanced by hypoxic preconditioning. (researchsquare.com)
  • For this purpose, a cellular model of senescent myocardial cells was set up and evaluated using colorimetric, fluorimetric, and immunometric techniques. (hindawi.com)
  • These results suggested that naringenin has antiaging effects on myocardial cells. (hindawi.com)
  • Because aging has been demonstrated to be directly related to the occurrence of cardiac disorders, together, the data have prompted us to investigate the effects of Nar in a cellular model of aged myocardial cells. (hindawi.com)
  • The results demonstrated that Nar exerts effective antiaging properties in myocardial cells. (hindawi.com)
  • Gene expression profiling (RNA-seq) and genome-wide sequencing of methylated DNA (MBD-seq) identified dynamic changes in the cardiac methylome during postnatal development [2545 differentially methylated regions (DMRs) from P1 to P14 in the mouse]. (nih.gov)
  • Drinking grape juice 30 minutes before meals for a week following each cycle of chemotherapy doesn't seem to reduce nausea or vomiting caused by chemotherapy. (medlineplus.gov)
  • New study finds that short fasting cycles can work as well as chemotherapy, and the two combined greatly improve survival. (sciencedaily.com)
  • Man may not live by bread alone, but cancer in animals appears less resilient, according to a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting. (sciencedaily.com)
  • And without exception, "the combination of fasting cycles plus chemotherapy was either more or much more effective than chemo alone," said senior author Valter Longo, professor of gerontology and biological sciences at the University of Southern California. (sciencedaily.com)
  • In a case report study with self-reported data published in the journal Aging in 2010, 10 cancer patients who tried fasting cycles perceived fewer side effects from chemotherapy. (sciencedaily.com)
  • In several cases, the fasting cycles were as effective as chemotherapy. (sciencedaily.com)
  • In the case of melanoma, the cancer cells became resistant to fasting alone after a single round, but the single cycle of fasting was as effective as chemotherapy in reducing the spread of cancer to other organs. (sciencedaily.com)
  • note that the denuded tubular epithelial cells clump together because of rearrangement of intercellular adhesion molecules. (medscape.com)
  • The tubular epithelial cells of the S3 segment of the proximal tubule in the outer stripe of the medulla, at the corticomedullary junction, are most susceptible to ischemic injury as these cells live in a relatively hypoxic environment. (medscape.com)
  • Primary endometrial epithelial cells for cell therapy are largely hampered with the extremely limited proliferation capacity of uterine epithelial cells. (biomedcentral.com)
  • This study was to evaluate whether IUA is curable with conditionally reprogrammed (CR) endometrial epithelial cells. (biomedcentral.com)
  • During menses, the epithelial cells re-epithelialize the exposed surface and regenerate the new functionalis under the control of estrogen, while the glands remain in the basalis layer [ 2 ]. (biomedcentral.com)
  • This new field of study is called mitochondrial dynamics and it reveals how abnormalities in the life cycle of mitochondria (including the ways mitochondria divide (fission), join together (fusion) and are eliminated) result in disease causing changes in cell growth and survival. (queensu.ca)
  • These results indicate that cardiac Hmox1 induction not only prevents heme toxicity, but also regulates the timing and registration of genetic programs for mitochondrial quality control that limit cell death, pathological remodeling, and cardiac fibrosis. (jci.org)
  • In brief, apoptosis is triggered when "pro-death/damage sensing" BH3-only proteins activate the downstream effector molecules BAX and BAK, which dimerize on the mitochondrial outer membrane surface and permeabilize it, triggering the release of cytochrome C, caspase activation and committing the cell to programmed death. (biomedcentral.com)
  • MSC co-culture with skin fibroblasts from mitochondrial disease patients rescued aberrant mitochondrial morphology from a fission state to a more fused appearance indicating an effect of MSC co-culture on host cell mitochondrial network formation. (frontiersin.org)
  • Accordingly, one of the major limitations in the efforts to reduce the incidence of AKI in cardiac surgery is the lack of a real-time monitor of renal perfusion. (justia.com)
  • uk/cycling/2022/08/24/rab-wardell-dies-cardiac-arrest-two-days-winning-scottish-mountain/https://www. (harry-friseur.de)
  • Postsynaptic membranes contain two voltage-gated calcium channels (L-type & T-type) as well as a sodium/calcium exchanger, but the NMDA channel is particularly adept at allowing large amounts of calcium ion to enter the cell. (benbest.com)
  • Sleep difficulties can also lead to a chain of events that can increase sodium retention, arterial stiffness, and cardiac output, potentially leading to hypertension. (daijiworld.com)
  • The recent publication in Stem Cell Research and Therapy by Wagh and colleagues reports a novel regulatory role for miR-363 in cardiomyocyte specification. (biomedcentral.com)
  • A cycle of 50% occurs when chest compression equals chest recoil. (unboundmedicine.com)
  • Cardiac arrest occurs when the heart's electrical system malfunctions. (popsci.com)
  • Administration of CHK1-targeted anticancer therapies is associated with an increased cumulative risk of cardiac complications, which is further amplified when combined with gemcitabine. (bvsalud.org)
  • High levels of intracellular calcium ion activate proteolytic enzymes (known as calpains) that break down many cell proteins, particularly those in the cytoskeleton of neurons (spectrin, neurofilament and microtubule-associated protein). (benbest.com)
  • While normal cells deprived of nutrients enter a dormant state similar to hibernation, the researchers saw that the cancer cells tried to make new proteins and took other steps to keep growing and dividing. (sciencedaily.com)
  • BH3-mimetics are a novel drug class of small molecule inhibitors of BCL2 family proteins which restore apoptosis in malignant cells. (biomedcentral.com)
  • Little adrenaline is found in other tissues, mostly in scattered chromaffin cells and in a small number of neurons that use adrenaline as a neurotransmitter. (wikipedia.org)
  • Neurologic abnormalities induced by heat stroke involve the brain (especially the basal ganglia and thalami), cerebellum, anterior horn cells in the spinal cord, and peripheral nerves. (ajnr.org)
  • At higher levels of exposure in humans, lead produces cardiac lesions and electrocardiographic abnormalities. (cdc.gov)
  • Queen's University professor Stephen Archer's (Department of Medicine) research has revealed that in serious human diseases (such as pulmonary hypertension, lung cancer, cardiac arrest and neurologic disease) the cell's power source, known as mitochondria, displays an abnormal structure. (queensu.ca)
  • This explosion in the understanding of the once secret lives of mitochondria will almost certainly advance our understanding of an important mechanism for cell death and cell growth," says Dr. Archer. (queensu.ca)
  • After hyperoxia, HO-1(CM) -/- hearts showed suppression of the Pgc-1α/nuclear respiratory factor-1 (NRF-1) axis, swelling, low electron density mitochondria by electron microscopy (EM), increased cell death, and extensive collagen deposition. (jci.org)
  • Adenosine Triphospate is the vital molecule that stores energy within the mitochondria (organelles) which reside in our cells. (magnesiumandhealth.com)
  • It is estimated that between 200 and 2000 mitochondria reside in each cell. (magnesiumandhealth.com)
  • The muscle cells have a higher number of mitochondria compared to most other cells, so as to cope with the energy necessary to work our muscles efficiently, this includes of course, our heart. (magnesiumandhealth.com)
  • Under physiological circumstances, the resistance of the endothelial cell lining to interactions with platelets and coagulation factors prevents thrombosis. (medscape.com)
  • A link between the sympathetic nervous system and the lungs was shown in 1887 when Grossman showed that stimulation of cardiac accelerator nerves reversed muscarine-induced airway constriction. (wikipedia.org)
  • Defibrillation is nonsynchronized random administration of shock during a cardiac cycle. (medscape.com)
  • Cardioversion is a synchronized administration of shock during the R waves or QRS complex of a cardiac cycle. (medscape.com)
  • In this article I attempt to evaluate the nature & extent of ischemic & reperfusion injury -- primarily focused on the impact for cryonics (although certainly relevant to stroke and cardiac arrest). (benbest.com)
  • Excessive glutamate release resulting in excessive Ca +2 entry into cells is the excitotoxicity which initiates the brain ischemic damage seen in stroke and cardiac arrest. (benbest.com)
  • Belantamab mafodotin is an antibody-drug conjugate that contains belantamab, an afucosylated humanised monoclonal IgG1k antibody specific for B cell maturation antigen (BCMA), produced using recombinant DNA technology in a mammalian cell line (Chinese Hamster Ovary) that is conjugated with maleimidocaproyl monomethyl auristatin F (mcMMAF). (medicines.org.uk)
  • In this genetic association study of 413 adults who had unexplained SCD, nearly one-fifth of individuals had pathogenic or likely pathogenic genetic variants consistent with inherited cardiomyopathies or arrhythmia syndromes, despite having normal cardiac findings. (cdc.gov)
  • Under these conditions, hypoperfusion initiates cell injury that often, but not always, leads to cell death. (medscape.com)
  • Persistent hypoperfusion injures tubular cells in the straight portion of the proximal tubules and the thick ascending limb of the loop of Henle, especially as it dips into the relatively hypoxic medulla. (medscape.com)
  • Relevant cellular senescence markers, such as X-gal staining, cell cycle regulator levels, and the percentage of cell cycle-arrested cells, were found to be reduced in the presence of naringenin. (hindawi.com)
  • This cell then varieties dedicated stem cells that may form specific kinds of blood cells. (ehd.org)
  • Disruptions to the sleep/wake cycle can also influence blood vessel constriction/relaxation activity and the function of cells that regulate the vascular tone," said Haghayegh. (daijiworld.com)
  • What we're seeing is that the cancer cell tries to compensate for the lack of all these things missing in the blood after fasting. (sciencedaily.com)
  • CD95 counts in the 3 types of white blood cells were significantly higher in PEM infants and showed improvement after nutritional rehabilitation yet not reaching the control values. (who.int)
  • The hemostatic system consists of platelets, coagulation factors, and the endothelial cells lining the blood vessels. (medscape.com)
  • The ordinary cycle lasts 0.8 sec with the heart beating approx. (unboundmedicine.com)
  • Although the heart seems to be working continuously, it actually rests for a good portion of each cardiac cycle. (unboundmedicine.com)
  • What happens to your heart during cardiac arrest? (popsci.com)
  • A group of heart cells work together as a pacemaker to create electricity, which transmits through the heart and gets it to contract and relax. (popsci.com)
  • The group of heart cells are "like an on-off switch that shoots electricity in the heart which tells it when to squeeze," explains Shephal Doshi , director of cardiac electrophysiology and pacing at Providence Saint John's Health Center. (popsci.com)
  • The blockage deprives heart cells of oxygen, which affects their electrical impulses, resulting in an abnormal heart rhythm. (popsci.com)
  • It causes all of the heart cells to contract simultaneously. (medscape.com)
  • Cardiac injuries, on the other hand, are less common. (popsci.com)
  • However, while these sports-related cardiac injuries are incredibly rare, they can be fatal, Skopicki cautions. (popsci.com)
  • A cell cycle arrest in early S-phase and in G 0 /G 1 -phase was also found after exposure to cisplatin and sunitinib malate, in isolation, respectively. (hindawi.com)
  • 1 Our temperature fluctuates with the circadian cycle as in all other living organisms (circadian rhythms occur in 24-hour cycles [circa = around and dian = day]), and in this way, our bodies can keep track of the duration of normal days over our life span. (ajnr.org)
  • Contraceptives suppress the circamensal cycle and result in elevations of temperature of about 0.5°C throughout the entire month. (ajnr.org)
  • Analgesia, sedation, and neuromuscular blockade during targeted temperature management after cardiac arrest. (mainehealth.org)
  • This rapidly evolving discipline has already identified several new targets for therapy for diseases ranging from Parkinsonism and pulmonary hypertension to cardiac arrest. (queensu.ca)
  • Ideally, you ought to choose a SARM that targets the right cells. (poker-24x7.us)