AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
AdenocarcinomaAdenocarcinoma, Bronchiolo-AlveolarCarcinoma in SituCarcinomaNeoplasm InvasivenessAdenocarcinoma, MucinousCarcinoma, Pancreatic DuctalPrecancerous ConditionsBarrett EsophagusColon, TransverseCarcinoma, Squamous CellPancreatic NeoplasmsAdenomaImmunohistochemistryLung NeoplasmsIntestinal PolypsProstatic Intraepithelial NeoplasiaColonic NeoplasmsCarcinoma, HepatocellularUterine Cervical NeoplasmsTumor Markers, BiologicalProstatePrognosisHyperplasiaBiopsyProstatic NeoplasmsEsophageal NeoplasmsDisease ProgressionCell Transformation, NeoplasticStomach NeoplasmsCarcinoma, PapillaryAdenocarcinoma, PapillaryLiver NeoplasmsNeoplasm StagingCell Line, TumorCarcinoma, Ductal, BreastGene Expression Regulation, NeoplasticCarcinoma, Basal CellTumor Cells, CulturedCardiaCarcinoma, Small CellCarcinoma, EndometrioidCarcinoma, Transitional CellCarcinoma, AdenosquamousCarcinoma, BronchogenicCarcinoma, Signet Ring CellCarcinoma, NeuroendocrineCarcinoma, Adenoid CysticNeoplasms, Multiple PrimaryEndometrial NeoplasmsCarcinoma, Intraductal, NoninfiltratingLymphatic MetastasisNeoplasm MetastasisBreast NeoplasmsNeoplasm ProteinsImmunoenzyme TechniquesCarcinoma, MedullaryDNA, NeoplasmKeratin-7Ovarian NeoplasmsAdenocarcinoma, Clear CellCarcinoma, LobularMice, NudeSurvival RateThyroid NeoplasmsColorectal NeoplasmsNeoplasm TransplantationRetrospective StudiesNasopharyngeal NeoplasmsAntineoplastic AgentsRNA, MessengerEsophagogastric JunctionSurvival AnalysisCarcinoma, Non-Small-Cell LungCarcinoma, Large CellMammary Neoplasms, ExperimentalCarcinoma, MucoepidermoidNeoplasm Recurrence, LocalTissue Array AnalysisAntigens, NeoplasmCarcinoma, DuctalReverse Transcriptase Polymerase Chain ReactionTreatment OutcomeTumor Suppressor Protein p53Rectal NeoplasmsGallbladder NeoplasmsCell ProliferationMetaplasiaHead and Neck NeoplasmsIntestinal NeoplasmsMutationCecal NeoplasmsCarcinoembryonic AntigenAmpulla of VaterCommon Bile Duct NeoplasmsUrinary Bladder NeoplasmsApoptosisFatal OutcomeMouth NeoplasmsKaplan-Meier Estimate
Cell carcinomaSquamous cell cancersCancersDysplasiaTumorsPrognosisGastricDiagnosisMucinous adenocarcinomaSitu and invasiveTumorHistologicallyHistopathologyUrothelial carcinomasMalignantBreastColorectalMetastaticLesionsHistologic sectionsLung adenocarcinomaEpitheliumEndocervicalColonicEndometrioidNeedle biopsyBronchioloalveolarSpecimensEndoscopicChemotherapyMutationsGastroesophagealIncidenceMuscularisLesion
Cell carcinoma32
  • Cytokeratin 10/13, 14, 7, 8, and 18 in invasive squamous cell carcinoma and adenocarcinoma of the uterine cervix. (bmj.com)
  • Transitional cell carcinoma, also called urothelial carcinoma, is the most common type of bladder cancer. (emedicinehealth.com)
  • Urothelial carcinoma (transitional cell carcinoma): This is by far the most common type of bladder cancer in the United States. (emedicinehealth.com)
  • In transitional cell carcinoma, these normal lining cells undergo changes that lead to the uncontrolled cell growth characteristic of cancer. (emedicinehealth.com)
  • We report a case of simultaneous Squamous cell carcinoma(SCC) of cervix and fallopian tube (invasive). (amrita.edu)
  • The benefits of neoadjuvant chemoradiation (NCRT) compared to upfront esophagectomy (UE) in esophageal squamous cell carcinoma (ESCC) is controversial. (springer.com)
  • Comparison of neoadjuvant chemotherapy versus upfront surgery with or without chemotherapy for patients with clinical stage III esophageal squamous cell carcinoma. (springer.com)
  • A propensity-matched analysis comparing survival after esophagectomy followed by adjuvant chemoradiation to surgery alone for esophageal squamous cell carcinoma. (springer.com)
  • Patterns of recurrence after oesophagectomy and postoperative chemoradiotherapy versus surgery alone for oesophageal squamous cell carcinoma. (springer.com)
  • Pre- versus postoperative chemoradiotherapy for locally advanced esophageal squamous cell carcinoma. (springer.com)
  • Upfront surgery and pathological stage-based adjuvant chemoradiation strategy in locally advanced esophageal squamous cell carcinoma. (springer.com)
  • Here, we report an unusual combination of bilateral ovarian SMBT and clear cell carcinoma associated with polypoid endometriosis of the colon, in a 62-year-old woman. (hindawi.com)
  • To the best of our knowledge, this is the first case of this unusual combination of ovarian seromucinous tumor and clear cell carcinoma to be reported in the English literature. (hindawi.com)
  • A few studies have reported tumors coexisting with SMBTs, such as endometrioid adenocarcinoma [ 4 ] and squamous cell carcinoma [ 5 ]. (hindawi.com)
  • Here, we describe the first case, to our knowledge, of an unusual combination of ovarian SMBT and clear cell carcinoma. (hindawi.com)
  • 2. Measure the levels of genetic instability using thick tissue sections with progressive histological stages of Non Small Cell Carcinomas (Sqamous cell carcinoma and adenocarcinomas): morphologically normal epithelium, hyperplasia, dysplasia, carcinoma in situ and invasive carcinoma. (europa.eu)
  • Women with primary untreated invasive squamous-cell carcinoma, adenosquamous carcinoma, or adenocarcinoma of the cervix of stage IIB, III, or IVA, without involvement of the para-aortic lymph nodes, were enrolled. (nih.gov)
  • Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
  • The large cell carcinoma class has been enriched with several variants, including the LCNEC and the basaloid carcinoma, both with a dismal prognosis. (ersjournals.com)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • Microinvasive adenocarcinoma is not as well studied as microinvasive squamous cell carcinoma because diagnosis of adenocarcinoma cannot be ascertained for early invasive lesions. (koreamed.org)
  • Avelumab is currently approved by the FDA for the treatment of metastatic Merckel cell carcinoma (mMCC) and platinum-refractory metastatic urothelial carcinoma. (bcan.org)
  • The other prevalent types are clear cell carcinoma and papillary serous adenocarcinoma, which carry a worse prognosis and high risk of invasive or metastatic disease. (logicalimages.com)
  • Previous work in our laboratory identified keratin 17 (K17) as a specific and sensitive biomarker for high-grade squamous intraepithelial lesions and cervical squamous cell carcinoma (SCC). (medscape.com)
  • Cervical cancer has multiple histologic subtypes, with squamous cell carcinoma (SCC) accounting for approximately 75% of cases and invasive adenocarcinoma accounting for 10% to 15% of cases. (medscape.com)
  • [ 11-13 ] By contrast, we discovered, using laser capture microdissection and mass spectrometry, that keratin 17 (K17) could predict the overall survival of patients with cervical squamous cell carcinoma more accurately than grade, stage, or any other clinicopathologic features. (medscape.com)
  • Cystoscopy revealed a pedunculated mass in the right posterior-lateral wall, inferior to the transplant urethral orifice, and biopsy of this mass showed invasive small cell carcinoma with a prominent adenocarcinoma component. (cdc.gov)
  • most are classified histologically as squamous cell carcinoma (OPSCC). (cdc.gov)
  • The relationship between blood pressure and risk of renal cell carcinoma. (who.int)
  • Epidemiology of Renal Cell Carcinoma: 2022 Update. (who.int)
  • Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort. (who.int)
  • Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. (who.int)
Squamous cell cancers2
  • Most squamous cell cancers are invasive. (medicalnewstoday.com)
  • therefore, HPV-associated cancers were defined as invasive cancers at anatomic sites with cell types in which HPV DNA frequently is found, including carcinomas of the cervix (i.e., squamous cell cancers [SCC], adenocarcinomas, and other carcinomas) and SCC of the vulva, vagina, penis, oropharynx, and anus (including rectal SCC) ( 4 ). (cdc.gov)
Cancers6
  • Invasive cancers are harder to treat. (medicalnewstoday.com)
  • About 1% of bladder cancers are adenocarcinomas. (medicalnewstoday.com)
  • Fewer than 1% of bladder cancers are small cell carcinomas. (medicalnewstoday.com)
  • In the United States, urothelial carcinomas account for more than 90% of all bladder cancers. (emedicinehealth.com)
  • Our model considers the impact of vaccination on squamous cell carcinomas, adenocarcinomas, cervical cancers due to high risk human papillomavirus types not in the vaccine, non-cervical cancers, and anogenital warts. (bmj.com)
  • Studies of invasive cervical cancers demonstrate that up to 99% of cervical cancer specimens have HPV detected ( 4 - 7 ). (cdc.gov)
Dysplasia4
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • Dysplasia and carcinoma in situ are histopathologic changes predictive of future development of invasive carcinoma. (wcrf.org)
  • We propose a model of changes ranging from viral reactivation to dysplasia to invasive carcinoma. (northwestern.edu)
  • The lesion was, therefore, diagnosed as an intramucosal invasive (Tis) carcinoma , rather than high-grade dysplasia, according to the World Health Organization definition. (bvsalud.org)
Tumors8
  • Chemotherapy uses drugs to target and kill cancer cells or to shrink tumors and allow a surgeon to use a less invasive procedure. (medicalnewstoday.com)
  • Nuclear stratification was noted, but no invasive growth was apparent in these cystic tumors. (hindawi.com)
  • The tumors showed glandular proliferation or small nests with invasive growth (Figure 2(d) ). (hindawi.com)
  • Adenocarcinoma is the malignant counterpart to adenoma, which is the benign form of such tumors. (knowbreastcancer.org)
  • The most common malignant tumor of the perianal region is the anal sac (gland) carcinoma accounting for 16.5% of all perianal tumors. (livs.org)
  • These tumors are locally invasive and metastasize early in the course of the disease. (livs.org)
  • Around 0.2% of all solid tumors contain oncogenic NRG1 gene fusions, 2 including around 31% of cases of invasive mucinous adenocarcinoma of the lung. (onclive.com)
  • Staining tended to be strongest at the periphery of pseudoglandular groups and at the invasive front of tumors. (medscape.com)
Prognosis2
  • Clinicopathologic Impact of NANOG, ZEB1, and EpCAM Biomarkers on Prognosis of Serous Ovarian Carcinoma. (nih.gov)
  • [ 5 ] It has been shown that histologic type is an independent prognostic factor in cervical cancer, with adenocarcinoma subtypes being associated with a poorer prognosis compared with SCC. (medscape.com)
Gastric3
  • Aidexi is indicated for the treatment of locally advanced or metastatic gastric cancer (including gastroesophageal junction adenocarcinoma) with HER2 over-expression in patients who have received at least two types of systemic chemotherapy. (pharmaceutical-technology.com)
  • [ 15 ] Other studies have shown K17 to be a negative prognostic indicator in gastric adenocarcinoma, bladder carcinoma, epithelial ovarian carcinoma, and triple-negative breast carcinoma. (medscape.com)
  • 2 Diagnosis of small cell (neuroendocrine) or mucinous adenocarcinoma of cervical cancer (ie, mucinous NOS, intestinal type, signet ring cell type, invasive stratified mucin producing carcinoma and gastric type) based on 2020 WHO classification of cervical cancer. (who.int)
Diagnosis7
  • Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive diagnosis of cancer. (nature.com)
  • Adeno-carcinoma is the predominant type and is included in the criteria established by Finn and Javert for diagnosis of primary carcinoma of fallopian tube [2]. (amrita.edu)
  • Note: A prior diagnosis of non-muscle-invasive bladder cancer (≤T1) managed with transurethral resection with or without intravesicular therapy (now with muscle invasion) is allowed. (bcan.org)
  • ABSTRACT To compare clinical (non-invasive) diagnosis with bronchoscopic (invasive) diagnosis, a total of 50 patients with chronic pneumonia (sputum smear-negative for tuberculosis) were examined. (who.int)
  • When should an invasive method rate, e.g. when the radiograph has failed to of diagnosis be requested? (who.int)
  • The cause of non-resolving pneumonias the primary or clinical diagnosis with final may be non-infectious or infectious and diagnosis done by FOB and to find out how usually invasive diagnostic techniques are well matched they were. (who.int)
  • A total of 810 prostatic needle core biopsy specimens obtained from 100 patients with suspected prostatic adenocarcinoma were retrieved from the archival material at King Khalid University Hospital, Riyadh, and classified independently by 3 experienced histopathologists who were blinded to the original diagnosis. (who.int)
Mucinous adenocarcinoma1
  • This picture depicts an abdominal CT scan of a 7 year-old boy with a mucinous adenocarcinoma of the ascending colon. (medscape.com)
Situ and invasive1
  • Although p16 INK4a has been well established as sensitive and accurate diagnostic biomarker for endocervical adenocarcinoma in situ and invasive adenocarcinoma in histologic sections and in cervical cytology specimens, clinical and diagnostic features alone have limited power to predict the survival of patients with endocervical adenocarcinoma. (medscape.com)
Tumor5
  • Mice with mutations in transforming growth factor-β1 gene introduced into 129/Sv Rag2 mutant mouse accelerates adenocarcinomas with strong local invasion suggesting a role for genetic background in tumor development. (wikipedia.org)
  • This type of tumor is locally invasive and spreads rapidly. (cats.com)
  • 12 ] mapped non-synonymous somatic mutations of Breast Invasive Carcinoma and Colon Adenocarcinoma Tumor samples to their corresponding protein domains, in order to extract domains with significant mutation frequency. (biomedcentral.com)
  • With the destruction of the alveolar framework by tumor growth, BAC develops into mixed BAC and invasive adenocarcinoma, which is a natural model of transformation from carcinoma in situ to invasive carcinoma. (elis.sk)
  • Cases of invasive cervical cancer diagnosed in AN women aged 18 and above between 1980 and 2007 were identified from the Alaska Native Tumor Registry. (cdc.gov)
Histologically3
  • Invasive cancer cases were classified by anatomic site using the International Classification of Diseases for Oncology, Third Edition (ICD-O-3) § (Supplementary Table, https://stacks.cdc.gov/view/cdc/80649 ) and were histologically confirmed. (cdc.gov)
  • Adenocarcinoma can be histologically classified as terminal respiratory unit (TRU) and non-TRU types [5-7]. (knowbreastcancer.org)
  • Histologically confirmed transitional cell (urothelial) carcinoma of the bladder that is invasive into the muscularis propria (≥T2 disease) within 6 months of enrollment date. (bcan.org)
Histopathology2
  • Yet these adenocarcinomas do not metastasize and their histopathology is similar to that of the right side colon cancer in human with frequent mutation of the type II receptor for TGF-β. (wikipedia.org)
  • of prostatic adenocarcinoma among 3 Analysis histopathology consultants. (who.int)
Urothelial carcinomas1
  • We report 2 cases of kidney ± pancreas transplant recipients with evidence of BK polyomavirus reactivation, who developed aggressive urinary bladder urothelial carcinomas with adenocarcinomatous and/or micropapillary differentiation. (northwestern.edu)
Malignant2
Breast3
  • Breast cancer in cats comes in several different forms, with mammary adenocarcinoma being the most common. (cats.com)
  • On April 21st I had a core biopsy and today I was told that I have mucinous carcinoma of the breast. (breastcancer.org)
  • Reported MR imaging findings are variable, ranging from decreased diffuse contrast material enhancement to rapid, intense enhancement that is indistinguishable from breast carcinoma. (radiopaedia.org)
Colorectal1
  • These include polyps, sporadic colorectal carcinoma (CRC) and familial colon cancer (familial adenomatous polyposis [FAP]), and hereditary nonpolyposis colorectal cancer (HNPCC). (medscape.com)
Metastatic1
  • In May 2016, the Food and Drug Administration (FDA) granted accelerated approval for injections of atezolizumab (Tecentriq) to treat locally advanced or metastatic urothelial carcinoma. (medicalnewstoday.com)
Lesions1
  • Cases of endocervical adenocarcinoma (n = 90), adenocarcinoma in situ (AIS) (n = 32), benign glandular lesions (n = 36), and normal endocervical mucosa (n = 5) were selected from Stony Brook Medicine and the University of Massachusetts from 2002 to 2013. (medscape.com)
Histologic sections1
Lung adenocarcinoma4
  • found that pyroptosis-related genes can be used for prognostic prediction of skin cutaneous melanoma and lung adenocarcinoma, respectively. (nature.com)
  • The incidence of lung adenocarcinoma is increasing in many countries [4]. (knowbreastcancer.org)
  • In addition, myofibroblast positive expression was associated with lymph node metastasis, high stage, high grade, vascular invasion and shortened survival time in patients with lung adenocarcinoma. (elis.sk)
  • These data suggest that myofibroblasts are likely to facilitate the invasion and metastasis of the lung adenocarcinoma, and can be used as a prognostic marker. (elis.sk)
Epithelium1
  • Our main goal is to do a correlative study of genomic instability and telomere length during lung cancer progression, starting from normal lung epithelium to invasive carcinoma. (europa.eu)
Endocervical3
  • The sensitivity of Papanicolaou smears for detecting endocervical adenocarcinoma in situ (AIS) is very low. (cytojournal.com)
  • [ 16-20 ] There remains a critically important, unmet clinical need, however, to identify prognostic (as opposed to diagnostic) biomarkers of endocervical adenocarcinoma. (medscape.com)
  • Thus, the goal of this study was to determine if K17 expression is a negative prognostic biomarker associated with decreased survival of patients with endocervical adenocarcinoma. (medscape.com)
Colonic1
Endometrioid1
Needle biopsy1
  • Hello everyone, I am 56-year old former smoker (quit 7 years ago) and was just diagnosed with Adenocarcinoma In Situ based on needle biopsy done on a 1.3cm nodule in my right middle robe. (cancer.org)
Bronchioloalveolar2
Specimens3
  • In this study, the expression of myofibroblasts in BAC, mix-BAC and invasive adenocarcinoma was examined by immunohistochemical staining of surgical specimens from 102 patients. (elis.sk)
  • Our study assessed HPV genotypes found in invasive cervical cancer specimens from AN women diagnosed from 1980 to 2007. (cdc.gov)
  • This retrospective study aimed to assess the concordance and interobserver variation between histopathologists in reporting prostatic adenocarcinoma using material obtained from prostatic core biopsy specimens. (who.int)
Endoscopic1
  • We endoscopically diagnosed this lesion as an intramucosal or slightly invasive submucosal carcinoma with low confidence, and performed endoscopic mucosal resection to obtain a total biopsy . (bvsalud.org)
Chemotherapy1
  • In most cases all three types of therapy are used (surgery, radiation therapy, and chemotherapy) in the treatment of dogs with anal sac carcinoma. (livs.org)
Mutations1
  • A mouse model carrying mutations in ApcΔ716 and Smad4 (mothers against decapentaplegic homolog 4) is characterized with development of invasive adenocarcinomas. (wikipedia.org)
Gastroesophageal2
  • Durvalumab is under clinical development by AstraZeneca and currently in Phase III for Gastroesophageal (GE) Junction Carcinomas. (pharmaceutical-technology.com)
  • According to GlobalData, Phase III drugs for Gastroesophageal (GE) Junction Carcinomas have a 100% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. (pharmaceutical-technology.com)
Incidence2
  • To address these challenges, we developed an approach, called GEnome-wide Mutational Incidence for Non-Invasive detection of cancer (GEMINI), that can identify a much larger number of somatic alterations in cfDNA (Fig. 1 ). (nature.com)
  • Although screening programs have been very effective in decreasing the incidence of SCC by as much as 80%, [ 8 ] studies have shown a contrasting increase in the incidence of cervical adenocarcinoma, particularly in younger women. (medscape.com)
Muscularis1
  • Structural atypia was notable in the invasive front, indicating well-to-moderately differentiated adenocarcinoma , which invaded the lamina muscularis mucosae. (bvsalud.org)
Lesion1
  • Hematoxylin and eosin staining of the resected specimen showed that the surface of the lesion was well-differentiated adenocarcinoma . (bvsalud.org)