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  • primary
  • Our observations definitively establish IL-8 as a primary mediator of angiogenesis in bronchogenic carcinoma and offer a potential target for immunotherapies against solid malignancies. (rupress.org)
  • Fibrolamellar hepatocellular carcinoma ( FLC ) is a rare subtype of primary liver cancer. (wikidoc.org)
  • hepatocellular carcinoma
  • Advances in molecular characterization and novel gene-isolation techniques have vigorously expanded our understanding of hepatocellular carcinoma (HCC), a form of liver cancer that affects one million people annually, and generated many new therapeutic possibilities. (springer.com)
  • In Hepatocellular Carcinoma: Methods and Protocols, Nagy Habib and a team of basic and clinical researchers describe the wide variety of powerful new laboratory-based molecular methods currently being used for investigating and treating this disease. (springer.com)
  • Hepatocellular Carcinoma: Methods and Protocols offers experimental and clinical investigators a rich source of both basic science and clinical information on today's optimal use of gene therapy to treat and manage patients suffering from hepatocellular carcinoma. (springer.com)
  • Hepatocellular carcinoma is the sixth most prevalent cancer and the third most frequent cause of cancer-related death. (nih.gov)
  • Findings of randomised trials of sorafenib have shown survival benefits for individuals with advanced hepatocellular carcinoma, suggesting that molecular-targeted therapies could be effective in this chemoresistant cancer. (nih.gov)
  • Research is active in the area of pathogenesis and treatment of hepatocellular carcinoma. (nih.gov)
  • Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis. (wikipedia.org)
  • Children and adolescents are unlikely to have chronic liver disease, however, if they suffer from congenital liver disorders, this fact increases the chance of developing hepatocellular carcinoma. (wikipedia.org)
  • Young adults afflicted by the rare fibrolamellar variant of hepatocellular carcinoma may have none of the typical risk factors, i.e. cirrhosis and hepatitis. (wikipedia.org)
  • The risk of hepatocellular carcinoma in type 2 diabetics is greater (from 2.5 to 7.1 times the non diabetic risk) depending on the duration of diabetes and treatment protocol. (wikipedia.org)
  • A suspected contributor to this increased risk is circulating insulin concentration such that diabetics with poor insulin control or on treatments that elevate their insulin output (both states that contribute to a higher circulating insulin concentration) show far greater risk of hepatocellular carcinoma than diabetics on treatments that reduce circulating insulin concentration. (wikipedia.org)
  • small cell carc
  • As a class, NSCLCs are relatively insensitive to chemotherapy , compared to small cell carcinoma. (wikipedia.org)
  • Pie chart showing incidences of non-small cell lung cancers as compared to small cell carcinoma shown at right, with fractions of smokers versus non-smokers shown for each type. (wikipedia.org)
  • Small cell carcinoma Cells are usually round and are less than approximately 3 times the diameter of a resting lymphocyte and little evident cytoplasm. (wikipedia.org)
  • anaplastic
  • LCLC is differentiated from small cell lung carcinoma (SCLC) primarily by the larger size of the anaplastic cells, a higher cytoplasmic-to-nuclear size ratio, and a lack of "salt-and-pepper" chromatin. (wikipedia.org)
  • Refers
  • adeno = gland ) Refers to a carcinoma featuring microscopic glandular-related tissue cytology, tissue architecture, and/or gland-related molecular products, e.g., mucin . (wikipedia.org)
  • cancers
  • spindle cell carcinoma (containing elongated cells resembling connective tissue cancers), giant cell carcinoma (containing huge, bizarre, multinucleated cells), and sarcomatoid carcinoma (mixtures of spindle and giant cell carcinoma). (wikipedia.org)
  • Some of the more well known include the lesions containing pseudo-sarcomatous components: spindle cell carcinoma (containing elongated cells resembling connective tissue cancers), giant cell carcinoma (containing huge, bizarre, multinucleated cells), and sarcomatoid carcinoma (mixtures of spindle and giant cell carcinoma). (wikipedia.org)
  • uncommon
  • In the testis pure embryonal carcinoma is also uncommon, and accounts for approximately ten percent of testicular germ cell tumours. (wikipedia.org)
  • citation needed
  • Cytologic features of serous carcinoma are:[citation needed] Marked intragroup nuclear pleomorphism. (wikipedia.org)
  • citation needed] When found within the skin, mucinous carcinoma is commonly a round, elevated, reddish, and sometimes ulcerated mass, usually located on the head and neck. (wikipedia.org)
  • cervical
  • The carcinoma of tonsil usually spreads through the cervical lymph node levels II, III, IV, V, and retropharyngeal lymph nodes. (wikipedia.org)
  • head and neck
  • Int J Oral Surg 1985;14:485-92 Koch BB, Trask DK, Hoffman HT, Karnell LH, Robinson RA, Zhen W, Menck HR. National survey of head and neck verrucous carcinoma. (wikipedia.org)
  • rare
  • Bronchioloalveolar carcinoma (BAC) of the lung is the only form of CIS that can kill directly because, in rare cases (the "pneumonic form"), it expands greatly and fills the lungs, preventing breathing and causing other dire effects on the host. (wikipedia.org)
  • In the ovary, embryonal carcinoma is quite rare, amounting to approximately three percent of ovarian germ cell tumours. (wikipedia.org)
  • cancer
  • Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal , mesodermal or ectodermal germ layer during embryogenesis . (wikipedia.org)
  • oat-cell carcinoma ( oht -sel) n. see small-cell lung cancer . (encyclopedia.com)
  • Cancer 1998;83:204-12 Saranath D, Chang SE, Bhotie LT, Panchal RG, Kerr IB, Mehta AR, Johnson NW, Deo MG. High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India. (wikipedia.org)
  • Adrenocortical carcinoma (ACC, adrenal cortical carcinoma, adrenal cortical cancer, adrenal cortex cancer, etc.) is an aggressive cancer originating in the cortex (steroid hormone-producing tissue) of the adrenal gland. (wikipedia.org)
  • neck
  • As the tonsils consist of a rich network of lymphatics, the carcinoma may metastasise to the neck lymph nodes which many are cystic. (wikipedia.org)
  • clinical
  • The clinical features associated with metastasising embryonal carcinoma may include low back pain, dyspnoea, cough, haemoptysis, haematemesis and neurologic abnormalities. (wikipedia.org)