• Primary hepatocellular carcinoma (PHC) is one of the most serious malignant tumors with high morbidity and mortality. (wjgnet.com)
  • SOUTH SAN FRANCISCO, Calif.--( BUSINESS WIRE )-- Exelixis, Inc. (NASDAQ:EXEL) today announced that its global phase 3 CELESTIAL trial met its primary endpoint of overall survival (OS), with cabozantinib providing a statistically significant and clinically meaningful improvement in median OS compared to placebo in patients with advanced hepatocellular carcinoma (HCC). (businesswire.com)
  • Hepatocellular carcinoma is cancer that starts in the liver. (medlineplus.gov)
  • Hepatocellular carcinoma is the most common type of liver cancer. (medlineplus.gov)
  • Hepatocellular carcinoma is not the same as metastatic liver cancer . (medlineplus.gov)
  • NCCN clinical practice guidelines in oncology: hepatocellular carcinoma. (medlineplus.gov)
  • Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and the third most common cause of cancer mortality. (scirp.org)
  • The aim of the study was to determine the diagnostic accuracy of the Doppler sonography for differentiation of hepatocellular carcinoma (HCC) from other focal liver lesions by taking histopathology as a gold standard. (scirp.org)
  • On Doppler sonography 37 cases were positive for hepatocellular carcinoma and 33 cases were negative while 36 cases were positive and 34 negative on histopathology. (scirp.org)
  • tiation of Hepatocellular carcinoma from other focal liver lesions, detection and characterization of hepatocellular carcinoma. (scirp.org)
  • Sherman, M. (2005) Diagnosis of small hepatocellular carcinoma. (scirp.org)
  • Hepatocellular carcinoma (HCC) is the sixth most common cancer in the world and the third most fatal cancer [ 1 ]. (hindawi.com)
  • The Texas Hepatocellular Carcinoma Consortium was established in 2015 to reduce the burden and mortality of hepatocellular cancer (HCC) in Texas. (bcm.edu)
  • Elevar is inspired by Blue Faery's efforts to raise understanding of and advocate for patients with hepatocellular carcinoma and their families," said Elevar Vice President of Medical Affairs Bill Strickland. (kfor.com)
  • Liver cancer is the third leading cause of cancer-associated mortality, of which hepatocellular carcinoma (HCC) represents 90% of all primary liver cancers. (wjgnet.com)
  • At the same time, another programme such as cirrhosis, chronic active hepatitis was launched to vaccinate all schoolchil- or chronic persistent hepatitis, or primary dren at school entry as a second target hepatocellular carcinoma later in life [ 2 ]. (who.int)
  • Primary peritoneal carcinoma shows similar rates of tumor suppressor gene dysfunction (p53, BRCA, WT1) as ovarian cancer and can also show an increased expression of HER-2/neu. (wikipedia.org)
  • The term carcinoma of unknown primary site (CUPS) is used when dealing with a metastasis that occurs before primary tumor diagnosis. (medscape.com)
  • In dealing with cutaneous CUPS, the age, sex, and affected skin region of the patient, as well as the histology of the lesion, are useful in determining the location of the likely primary tumor. (medscape.com)
  • [ 2 ] On the other hand, some metastases may be epidermotropic and simulate a primary epidermal tumor. (medscape.com)
  • This type of cancer is called a cancer of unknown primary (CUP) or occult primary tumor . (vicc.org)
  • Adenoid cystic carcinoma (ACC) is a tumor characterized by slow growth and late distant metastasis. (hindawi.com)
  • Here, we report a case of ACC arising from minor salivary gland that metastasized to the colon 19 years after the primary tumor resection, with literature review of the clinical, histological, and molecular features of ACC. (hindawi.com)
  • Here, we report a case of ACC metastatic to the colon 19 years after resection of the primary tumor, to broaden the differential diagnosis of colorectal malignancies and to better understand the clinical, histological, and molecular features of ACC. (hindawi.com)
  • The primary tumor was 4 cm in size, with multiple positive margins and lingual nerve involvement. (hindawi.com)
  • Differential diagnosis initially included basosquamous carcinoma, acanthoytic squamous cell carcinoma, and adnexal tumor. (cdlib.org)
  • Clarification for the origin (either primary or secondary to skin) of the tumor via immunostaining to assess for a myoepithelial in situ component was performed, yielding a negative result. (cdlib.org)
  • We report on a 77-year-old man presenting with extremity weakness who was found to have a 2.5 cm brain metastasis from a subsequently discovered 1.6 cm clear cell RCC primary tumor. (canjurol.com)
  • Targeting α5β1 integrins might not only prevent metastasis of HNSCC but also delay the development of the primary tumor by reducing tumor cell viability. (cipsm.de)
  • CONCLUSION: Primary mucinous carcinoma of the eyelid is a low-grade malignant tumor with the potential for recurrence, although this may be reduced using Mohs surgery or excision with frozen section control. (duke.edu)
  • KEYNOTE-017 represents the longest observation to date of patients with advanced Merkel cell carcinoma receiving anti-PD-1 therapy in the first-line setting, and demonstrated durable tumor control in these patients. (merck.com)
  • A patient is considered to have a cancer of unknown primary origin when cancer is detected at one or more sites and routine evaluation fails to identify the primary tumor. (msdmanuals.com)
  • A multiplex ligation-dependent probe amplification method was used to compare differences in copy number in 39 common tumor-associated genes among 7 patients with parathyroid carcinoma and 14 age- and sex-matched subjects with parathyroid adenoma. (nih.gov)
  • A primary tumor was not found. (medscimonit.com)
  • The primary tumor had been treated 2 years previously. (unboundmedicine.com)
  • Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells. (bepress.com)
  • Certain attributes distinguish metastases from primary tumors. (medscape.com)
  • Small renal cell carcinoma (RCC) tumors are believed to have a negligible risk of metastasis. (canjurol.com)
  • OBJECTIVES: To report 4 cases of primary mucinous carcinoma of the eyelid, demonstrate how p63 expression aids diagnosis, and review the literature regarding the local recurrence potential of these eyelid tumors. (duke.edu)
  • Because the most common causative primary tumors are those of the testes, lungs, colon and rectum, and pancreas, examination of these areas must be thorough. (msdmanuals.com)
  • Increasing numbers of immunocytochemical stains can be used to test available cancerous tissue to help determine the primary site and can potentially identify tumors arising from the lung, colon, or breast. (msdmanuals.com)
  • In addition, immune peroxidase staining for immunoglobulin, chromosome studies, and immunophenotyping may help diagnose the various subtypes of malignant lymphomas, which may be difficult to recognize and differentiate from other tumors (even carcinomas) outside lymph nodes. (msdmanuals.com)
  • Adrenocortical tumors encompass a spectrum of diseases with often seamless transition from benign (adenoma) to malignant (carcinoma) behavior. (oncolink.org)
  • There are several different types, including adenocarcinoma, squamous cell carcinoma, and gastrointestinal stromal tumors (GISTs). (medicalnewstoday.com)
  • Surgical treatment may be considered for cases with even rapid-growing tumors such as gastric carcinoma with no evidence of multi-organ dissemination, especially when presenting with progressive neurological deterioration. (unboundmedicine.com)
  • Positron Emission Tomography/Computed Tomography (PET/CT) clearly demonstrated hotspots (SUV max: 7.7 for the primary mass and 4.2 for the metastatic lesion) at the same locations as the tumors detected by MRI, but no hot spots for lymph nodes and distant metastases were observed ( Figure 1D ). (oncologyradiotherapy.com)
  • Metastatic adenoid cystic carcinoma (ACC) in the colon is rare, with only a few case reports available [ 2 - 4 ]. (hindawi.com)
  • Patients must also have urothelial carcinoma that has spread locally, near where it started (locally advanced), or has spread to other parts of the body (metastatic). (bcan.org)
  • License Application (sBLA) seeking accelerated approval for KEYTRUDA, Merck's anti-PD-1 therapy, for the treatment of adult and pediatric patients with recurrent locally advanced or metastatic Merkel cell carcinoma (MCC). (merck.com)
  • ABSTRACT Primary small cell neuroendocrine carcinomas are extremely rare heterogeneous neoplasms . (bvsalud.org)
  • Paget disease may be a sign of underlying breast, genitourinary, or colon cancer, or it may be a primary neoplasm of indeterminate glands in the skin. (medscape.com)
  • Sometimes adnexal carcinomas arise in the setting of a precursor benign adnexal neoplasm, making diagnosis straightforward. (medscape.com)
  • Primary mucinous carcinoma (PMC) of the skin is a rare malignant neoplasm deriving from sweat glands [ 1 ]. (cdlib.org)
  • Extrapulmonary small-cell carcinoma (SCC) is a rare neoplasm that shares certain features with its pulmonary counterpart and occurs predominantly in the gastrointestinal tract (GIT). (mdpi.com)
  • Primary carcinoma of the fallopian tube is a rare neoplasm, accounting for only 0.3-1.1% of all gynecological malignancies [1]. (amrita.edu)
  • No radionuclide scan is needed for a reading of "suspicious for papillary carcinoma" or "Hürthle cell neoplasm", as either lobectomy or total thyroidectomy is recommended depending on the nodule size and risk factors. (medscape.com)
  • Carcinoma of unknown primary (CUP) is a rare disease in which malignant (cancer) cells are found in the body but the place the cancer began is not known. (vicc.org)
  • The most common primary site of colorectal metastasis is the breast, followed by the lung and malignant melanoma [ 1 ]. (hindawi.com)
  • Berstein L, Gurney JG: Carcinomas and other malignant epithelial neoplasms. (oncolink.org)
  • A rare case of primary malignant small cell carcinoma combined with urothelial cell carcinoma in the ureter. (ac.ir)
  • Merkel cell carcinoma, a rare type of skin cancer, is an aggressive and fast-growing disease that has been associated with mortality rates higher than other types of skin cancer, including melanoma," said Dr. (merck.com)
  • We look forward to working closely with the FDA throughout the review process and to bringing KEYTRUDA to patients with Merkel cell carcinoma. (merck.com)
  • Merkel cell carcinoma is an aggressive and rare form of skin cancer that is often caused by a Merkel cell associated polyomavirus. (merck.com)
  • Merkel cell carcinoma is more likely to spread to other parts of the body than most types of skin cancer. (merck.com)
  • Immuno- histochemical distinction between Merkel cell carcinoma and small cell carcinoma of the lung. (ac.ir)
  • Distant metastases arise in 20-30% of patients with squamous cell carcinoma of the head and neck (HNSCC) in the 2 years following treatment. (cipsm.de)
  • This combines the UICC TNM 8 guidance for skin carcinoma of the head and neck and carcinoma of the skin (essentially limbs and trunk but excluding eyelid, vulva, penis, non-hair bearing lip and non-hair bearing perianal skin within 5cm of the perianal margin). (cancer.org.au)
  • A contralateral nodal metastasis (unlike with skin carcinoma of head and neck below) represents a distant metastasis. (cancer.org.au)
  • Small cell neuroendocrine carcinoma (NEC) that arises from the tonsil is a particularly rare head and neck carcinoma. (ac.ir)
  • Berta E, Atallah I, Reyt E, Boyer E, Karkas A, Righini CA. The role of tonsillectomy in the initial diagnostic work-up of head and neck squamous cell carcinoma of unknown primary. (ac.ir)
  • Advanced head and neck squamous cell carcinoma (HNSCC) is treated with radiotherapy, chemotherapy, targeted therapy or a combination of these treatments. (researchsquare.com)
  • Here we describe the results from a phase Ib clinical trial (NCT02274155) in which 17 patients with locally advanced head and neck squamous cell carcinoma (HNSCC) received a murine anti-human OX40 agonist antibody (MEDI6469) prior to definitive surgical resection. (bepress.com)
  • Background: Reversible schizophrenia-like syndromes have been reported to occur with small-cell carcinoma of the lung, thymoma, and hematological disorders.Case Report: A 56-year-old man was admitted due to an acute psychosis characterized by delusions, agitation,and aggressive outbursts. (medscimonit.com)
  • Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and one of the most common cancers overall in the United States. (medscape.com)
  • Medical records were assessed retrospectively for 28 patients with chronic lymphocytic leukemia who underwent surgical excision of cutaneous squamous cell carcinoma and for 56 matched control subjects. (nih.gov)
  • The rate of metastasis and mortality from cutaneous squamous cell carcinoma were determined on a per-patient basis. (nih.gov)
  • Compared with control subjects, chronic lymphocytic leukemia patients with cutaneous squamous cell carcinoma were more likely to have metastasis (P = .0031) and die of metastasis (P = .0033). (nih.gov)
  • Primary cutaneous adnexal carcinomas may be difficult to distinguish from metastases in certain situations. (medscape.com)
  • Mahalingam et al have shown that positive staining with D2-40, p63, and CK15 also favors a primary adnexal carcinoma. (medscape.com)
  • A diagnosis of cutaneous mucinous carcinoma was made. (cdlib.org)
  • The final diagnosis was primary cutaneous mucinous carcinoma and definitive treatment was carried out via wide local excision. (cdlib.org)
  • Pure small cell carcinoma of the prostate (SCPCa) is a very rare condition usually with poor survival after diagnosis. (karger.com)
  • His doctors haven't confirmed a diagnosis (as far as I know) but have been talking about Carcinoma of Unknown Primary, which from my understanding is very rare and terminal. (cancercouncil.com.au)
  • my dad recently died, a little over a year after a primary brain tumour diagnosis. (cancercouncil.com.au)
  • Adeno-carcinoma is the predominant type and is included in the criteria established by Finn and Javert for diagnosis of primary carcinoma of fallopian tube [2]. (amrita.edu)
  • We evaluated associations of race, primary payer at diagnosis, and survival among patients diagnosed in Florida with lung cancer (n = 148,140) and breast cancer (n = 111,795), from 1996 through 2007. (cdc.gov)
  • Patients were categorized as IHS users for primary payer at diagnosis if they reported using IHS services in FCDS. (cdc.gov)
  • The primary outcome of our study, overall survival, was elapsed time from diagnosis to date of death or last patient encounter. (cdc.gov)
  • We report an early case of primary cutaneous mucinous carcinoma in a male patient with chronic actinic damage. (cdlib.org)
  • Scholars@Duke publication: Primary mucinous carcinoma of the eyelid: a clinicopathologic and immunohistochemical study of 4 cases and an update on recurrence rates. (duke.edu)
  • METHODS: Since 1991, we have examined 4 cases of primary mucinous carcinoma of the eyelid. (duke.edu)
  • Published cases of primary mucinous carcinoma involving the eyelid were identified using Ovid MEDLINE and PubMed and references within the articles. (duke.edu)
  • A loved one was just diagnosed with Squamous Cell Carcinoma of the Neck with unknown primary. (cancer.org)
  • For example, prostate cancer is very common, but cutaneous metastasis from prostate carcinoma is relatively uncommon. (medscape.com)
  • Some primary melanomas may arise in the dermis and simulate a metastasis. (medscape.com)
  • Our purpose was to compare squamous cell carcinoma metastasis and mortality between patients with chronic lymphocytic leukemia and control subjects. (nih.gov)
  • Extensive checkup revealed an isolated mediastinal metastasis of an undifferentiated carcinoma. (medscimonit.com)
  • A 42-year-old male presented with a rare intramedullary spinal cord metastasis from gastric carcinoma manifesting as rapidly worsening motor and sphincter disturbances. (unboundmedicine.com)
  • This phase Ib/II trial finds the best dose of selinexor and its effect with pembrolizumab in treating patients with urothelial carcinoma that are not eligible to receive the chemotherapy drug cisplatin, or have been given cisplatin and the cancer has gotten worse. (bcan.org)
  • I. To determine the recommended phase 2 dose (RP2D) of selinexor in combination with standard-dose pembrolizumab in patients with advanced urothelial carcinoma who are cisplatin-ineligible or platinum-refractory. (bcan.org)
  • To determine the objective response rate (ORR) of selinexor in combination with pembrolizumab in patients with advanced urothelial carcinoma who are cisplatin-ineligible or platinum-refractory. (bcan.org)
  • I. To further evaluate the toxicity profile of the combination of selinexor with pembrolizumab in patients with advanced urothelial carcinoma. (bcan.org)
  • To further evaluate the efficacy of the combination of selinexor with pembrolizumab in patients with advanced urothelial carcinoma as defined by progression-free survival (PFS). (bcan.org)
  • It is thus inferred that gain in copy number of CCND1 is implicated in the molecular pathogenesis of parathyroid carcinoma. (nih.gov)
  • Hypercalcemia in adult patients with Parathyroid Carcinoma (PC). (nih.gov)
  • The Epstein-Barr virus M81 strain, isolated from a nasopharyngeal carcinoma, induces potent spontaneous virus production in infected B cells. (nature.com)
  • Poorly differentiated carcinomas near or at midline regions of the mediastinum or retroperitoneum in young or middle-aged males should be considered germ cell neoplasms-even in the absence of a testicular mass. (msdmanuals.com)
  • The investigators hypothesize that nivolumab combined with neoadjuvant chemoradiotherapy (CRT) is safe and effective in patients with locally advanced esophageal squamous cell carcinoma (LAESCC). (centerwatch.com)
  • In patients with chronic lymphocytic leukemia, squamous cell carcinoma behaves aggressively. (nih.gov)
  • Patients with this type of carcinoma should be treated with a cisplatin -based regimen because nearly 50% have long disease-free intervals. (msdmanuals.com)
  • In a study, diabetes increased the odds of pathologic upgrading of renal cell carcinoma by 65% and 32%, among patients undergoing partial and radical nephrectomy, respectively. (renalandurologynews.com)
  • Investigators believe their study is the first to demonstrate the adverse impact of LVI on overall survival in patients with surgically treated renal cell carcinoma. (renalandurologynews.com)
  • Methods The type, location, and infiltration pattern of T cells were studied in 109 patients with primary VSCC FIGO stage I-III. (bmj.com)
  • Severe hypercalcemia in adult patients with primary HPT who are unable to parathyroidectomy. (nih.gov)
  • The most common renal cell carcinoma that develops in patients with end-stage renal disease and acquired cystic disease. (cismef.org)
  • Primary peritoneal cancer (PPC, or PPCa) is a cancer of the cells lining the peritoneum, or abdominal cavity. (wikipedia.org)
  • Furthermore, women with BRCA1/2 mutation have a 5% risk of developing primary peritoneal cancer even after prophylactic oophorectomy. (wikipedia.org)
  • The median survival of primary peritoneal carcinomas is usually shorter by 2-6 months time when compared with serous ovarian cancer. (wikipedia.org)
  • The primary cancer (the cancer that first formed) can spread to other parts of the body. (vicc.org)
  • In carcinoma of unknown primary, cancer cells have spread in the body but the place where the primary cancer began is unknown. (vicc.org)
  • Tests are done to find where the primary cancer began and to get information about where the cancer has spread. (vicc.org)
  • When tests are able to find the primary cancer, the cancer is no longer a CUP and treatment is based on the type of primary cancer. (vicc.org)
  • Sometimes the primary cancer is never found. (vicc.org)
  • The primary cancer is very small and grows slowly. (vicc.org)
  • The body's immune system killed the primary cancer. (vicc.org)
  • The primary cancer was removed during surgery for another condition and doctors didn't know cancer had formed. (vicc.org)
  • Because the place where the cancer started is not known, many tests and procedures may be done to search for the primary cancer. (vicc.org)
  • A laboratory test in which the DNA in a sample of cancer cells or tissue is studied to check for mutations (changes) that may help predict the best treatment for carcinoma of unknown primary. (vicc.org)
  • Adult primary liver cancer treatment (PDQ) - health professional version. (medlineplus.gov)
  • Cancer of unknown primary constitutes up to 7% of all cancers and poses a therapeutic dilemma because cancer treatment is typically determined by the specific primary tissue of origin. (msdmanuals.com)
  • Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB). (oncolink.org)
  • Vulvar squamous cell carcinoma (VSCC) is the predominant histologic type of vulvar cancer. (bmj.com)
  • Conducting implementation research in community-based primary care: a qualitative study on integrating patient decision support interventions for cancer screening into routine practice. (sutterhealth.org)
  • Lobular breast cancer is more frequently multifocal and bilateral than ductal carcinoma. (healthtap.com)
  • He was discharged from hospital 2 weeks later after having shoulder surgery, and for the past 2 months he has seen endless doctors who are all trying to search for a primary site of cancer. (cancercouncil.com.au)
  • HCC is the most common type of primary liver cancer, accounting for approximately 90% of primary liver cancers and most frequently occurring in people with chronic liver diseases, such as cirrhosis caused by hepatitis B, hepatitis C infection and Nonalcoholic Steatohepatitis (NASH). (kfor.com)
  • Founded in 2002, the mission of Blue Faery is to prevent, treat, and cure primary liver cancer through research, education, and advocacy. (kfor.com)
  • Bronchogenic carcinomas were the primary type of lung cancer among the gold miners. (cdc.gov)
  • The NCCN recommends that FNAB should be the primary test for differentiated thyroid cancer. (medscape.com)
  • They also show that families with the CDKN2A 113insArg mutation have an increased risk not only of multiple melanomas and pancreatic carcinoma but also of breast cancer. (lu.se)
  • More recent evidence has suggested that chronic H. pylori infection as well as early age of H. pylori -acquisition is a critical precursor to gastric carcinoma. (cdc.gov)
  • Esophageal Primary Intrahepatic Adenosquamous Carcinoma (IASC) is defined by the coexistence of both squamous and glandular elements in the same lesion histologically. (oncologyradiotherapy.com)
  • For most other unknown primary cancers, the responses to this regimen and to other multidrug chemotherapy regimens are modest and of brief duration (eg, median survival 1 year). (msdmanuals.com)
  • 95 percent) of primary liver cancers. (bcm.edu)
  • It accounts for approximately 90% of primary liver cancers and most frequently occurs in people with chronic liver diseases, such as cirrhosis caused by hepatitis B or hepatitis C infection. (kfor.com)
  • An excision was performed and the histopathology revealed a carcinoma comprising strands, nests, and occasional glandular structures. (cdlib.org)
  • For invasive cSCC, surgical excision and Mohs micrographic surgery are the primary treatment options. (medscape.com)
  • Histomorphological and molecular biological characteristics suggest that serous carcinomas, which include ovarian serous carcinoma, uterine serous carcinoma, Fallopian tube serous carcinoma, cervical serous carcinoma, and primary peritoneal serous carcinoma really represent one entity. (wikipedia.org)
  • We report a case of simultaneous Squamous cell carcinoma(SCC) of cervix and fallopian tube (invasive). (amrita.edu)
  • Increased 68 Ga-FAPI Activity in Primary Small Cell Neuroendocrine Carcinoma of the Gallbladder. (bvsalud.org)
  • We present 68 Ga-FAPI ( fibroblast activation protein inhibitor) PET /CT findings of small cell neuroendocrine carcinoma of the gallbladder in a 57-year-old woman . (bvsalud.org)
  • This rare gallbladder small cell neuroendocrine carcinoma demonstrated intense tracer uptake on 68 Ga-FAPI PET /CT. (bvsalud.org)
  • This demonstrates the potential value of 68 Ga-FAPI PET /CT for evaluation of gallbladder small cell neuroendocrine carcinoma . (bvsalud.org)
  • The intraoral biopsy of the tonsil confirmed primary small cell neuroendocrine carcinoma of the tonsil. (ac.ir)
  • Primary small cell neuroendocrine carcinoma of the tonsil: a case report and review of the literature. (ac.ir)
  • Primary Tonsillar Small Cell Neuroendocrine Carcinoma with Bone Metastases', Iranian Journal of Otorhinolaryngology , 34(4), pp. 195-198. (ac.ir)
  • Hyperplasia & metaplasia & chronic inflammatory cell infiltration into the stroma = carcinoma? (healthtap.com)
  • No significant differences were found in the survival from tumours largely refractive to therapy, e.g., carcinomas of the pancreas, lung and liver. (who.int)
  • The patient developed a new left lung mass 5 years ago, which was diagnosed as a primary lung adenocarcinoma. (hindawi.com)
  • Small cell lung carcinoma (SCLC): a clinicopathologic study of 100 cases with surgical specimens. (ac.ir)
  • Systemic treatment of adrenocortical carcinoma in children: data from the German GPOH-MET 97 trial. (oncolink.org)
  • The primary endpoint was to determine safety and feasibility of the anti-OX40 neoadjuvant treatment. (bepress.com)
  • Received 18 February 2006 the primary operation, but some will recur in spite of this treatment. (lu.se)
  • Primary Treatment. (bvsalud.org)
  • The primary endpoint for the trial is OS, and secondary endpoints include objective response rate and progression-free survival. (businesswire.com)
  • Primary end point was overall survival and secondary end points were surgical outcome and progression-free survival. (lu.se)
  • Primary cutaneous apocrine carcinomas can be particularly difficult to differentiate from adenocarcinomas of mammary origin because of the identical morphological and immunohistochemical features they may exhibit. (medscape.com)
  • Western blot and immunohistochemical analysis also demonstrated higher expression of CCND1 in carcinoma specimens than in adenoma samples. (nih.gov)
  • To our knowledge, this is the first reported case of small cell carcinoma of the CBD in which a radical resection was performed after successful neoadjuvant chemotherapy. (springer.com)
  • Cutaneous metastases from carcinoma (see the image below) are relatively uncommon in clinical practice, but they are very important to recognize. (medscape.com)
  • Based on available clinical trial data from various published trials conducted in the second-line setting of advanced HCC, the CELESTIAL trial statistics for the primary endpoint of OS assumed a median OS of 8.2 months for the placebo arm. (businesswire.com)
  • Segawa Y, Nakashima T, Shiratsuchi H, Tanaka R, Mitsugi K, Komune S. Small cell carcinoma of the tonsil treated with irinotecan and cisplatin: a case report and literature review. (ac.ir)