• A new study from a team based in Italy demonstrates that a higher free triiodothyronine to free thyroxine (fT3/fT4) ratio is associated with prolonged progression-free survival (PFS) and overall survival (OS) in metastatic renal cell carcinoma (mRCC). (medpagetoday.com)
  • Metastatic renal cell carcinoma (mRCC) accounts for one-third of all newly diagnosed renal cell cancers. (mdpi.com)
  • Barcelona, Spain (UroToday.com) In pretreated metastatic renal cell carcinoma (RCC), single agent checkpoint blockade immunotherapy with the PD-1 antibody nivolumab is associated with a response rate of 25% and improvement in overall survival relative to everolimus. (urotoday.com)
  • A personalized immunotherapy (AGS-003) nearly doubled expected progression-free survival and overall survival when added to standard sunitinib (Sutent) in patients with unfavorable-risk metastatic renal cell carcinoma, according to results from a single-arm phase II study. (urologytimes.com)
  • In the modern era of targeted therapy, some patients with metastatic renal cell carcinoma may be able to forgo nephrectomy and be treated with sunitinib (Sutent) alone, according to results of the phase III CARMENA trial reported during the Plenary Session at the 2018 ASCO Annual Meeting. (ascopost.com)
  • Nephrectomy has been the standard of care for metastatic renal cell carcinoma for 20 years, but now that targeted therapies have improved outcomes substantially, the question is whether all patients should have nephrectomy as well as targeted therapy. (ascopost.com)
  • Sunitinib alone is noninferior to nephrectomy followed by sunitinib in some intermediate- and poor-risk patients with metastatic renal cell carcinoma. (ascopost.com)
  • For more on the CARMENA trial in metastatic renal cell carcinoma, see an interview with Arnaud Méjean, MD , on The ASCO Post Newsreels at www.ascopost.com/videos . (ascopost.com)
  • Histological examination of a biopsy of the skin tumor revealed features of metastatic renal cell carcinoma of clear cell type. (cdlib.org)
  • This case represents an unusual clinical presentation of metastatic renal cell carcinoma that appears to have been translocated to the skin by the needle biopsy. (cdlib.org)
  • Many reports suggest a role for pulmonary metastasectomy in managing metastatic renal cell carcinoma [ 1 ]. (cdlib.org)
  • After we moved into the targeted therapy era in 2005, with vascular endothelial growth factor (VEGF) targeting agents demonstrating efficacy for metastatic renal cell carcinoma, a series of studies were designed to investigate the efficacy of adjuvant VEGF-targeting tyrosine kinase inhibitors. (ascopost.com)
  • At the time that approval for adjuvant sunitinib was granted, single-agent immune checkpoint inhibitors had demonstrated efficacy for patients with metastatic renal cell carcinoma and had entered the treatment armamentarium. (ascopost.com)
  • Excruciating, sharp, bandlike back pain may be an early warning for spinal cord compression due to metastatic renal cell carcinoma and should not be ignored. (medscape.com)
  • Mortality and morbidity after cytoreductive nephrectomy for metastatic renal cell carcinoma: a population-based study. (medscape.com)
  • Progression-free survival as a predictor of overall survival in metastatic renal cell carcinoma treated with contemporary targeted therapy. (medscape.com)
  • The therapeutic approach for renal cell carcinoma is guided by the probability of cure, which is related directly to the stage or degree of tumor dissemination. (medscape.com)
  • Other genetically linked conditions also increase the risk of RCC, including hereditary papillary renal carcinoma, hereditary leiomyomatosis, Birt-Hogg-Dube syndrome, hyperparathyroidism-jaw tumor syndrome, familial papillary thyroid carcinoma, von Hippel-Lindau disease and sickle cell disease. (wikipedia.org)
  • Other types of kidney cancer include transitional cell carcinoma of the renal pelvis and Wilms tumor. (massgeneral.org)
  • Finally, we will discuss distinctive novel/emerging renal neoplasms previously considered under the spectrum of ChRCC, low-grade oncocytic renal tumor and eosinophilic vacuolated tumor, with regard to their current significance and implications for future classification strategies. (lww.com)
  • Clear cell type renal cell carcinoma is a malignant tumor that can metastasize to many locations, but unusually spreads to thyroid. (scirp.org)
  • Clear cell renal carcinoma (CCRC) is a tumor with great metastatic capacity, although the presence of metastases in the thyroid gland is very uncommon. (scirp.org)
  • In August 2015 a right renal tumor and a sternal lithic lesion were found in control CT without signs of rectal relapse. (scirp.org)
  • Sixteen histological tumor subtypes exist and the most common are papillary, chromophobe and clear cell renal cell carcinoma (ccRCC) representing 85% of all RCC. (frontiersin.org)
  • 1999) Nephron sparing surgery for localized renal cell carcinoma: impact of tumor size on patient survival, tumor recurrence and TNM staging. (medscape.org)
  • 1997) Patterns of tumor recurrence and guidelines for followup after nephron sparing surgery for sporadic renal cell carcinoma. (medscape.org)
  • Renal cell carcinoma is the fourth most common metastatic tumor of the spine and the most common cancer to present as a neurologic deficit secondary to an undetected primary malignancy (1) . (ajnr.org)
  • We present a case of pulmonary metastasis from renal carcinoma with subcutaneous implantation of tumor cells along the needle tract after percutaneous needle biopsy of the lung. (cdlib.org)
  • The initial TNM staging of the renal tumor was T2 Nx M0. (cdlib.org)
  • After the operation, the pathological examination results suggested the following: Renal clear cell carcinoma, pT1aN0M0, the tumor sized ~4.0×4×3.5 cm 3 , with no lymph node cancer metastases or distant metastasis. (spandidos-publications.com)
  • Although papillary renal cell carcinoma (pRCC) is the second common renal malignant tumor , the current understanding of pRCC is poor. (bvsalud.org)
  • Using 6 biphasic clear cell renal cell carcinoma cases we show that sarcomatoid clear cell renal cell carcinoma shares characteristic markers associated with loss of von Hippel-Lindau tumor suppressor with conventional clear cell renal cell carcinoma and also exhibits a markedly higher proliferative index. (lu.se)
  • Assistance with the prescription drugs and biologics used in the treatment of renal cell carcinoma. (healthwellfoundation.org)
  • While significant advances have been made in the treatment of renal cancer, there remains a need for effective yet more tolerable treatments, both for single agent and combination use," said Brian Rini, M.D., Professor of Medicine at the Cleveland Clinic Lerner College of Medicine. (businesswire.com)
  • Advances in the treatment of renal disease. (medscape.com)
  • Creatinine measurements are useful in the diagnosis and treatment of renal diseases. (cdc.gov)
  • Sarcomatoid renal cell carcinoma (SRCC) is currently defined in the 2004 World Health Organization (WHO) classification of renal tumors as any histologic type of renal cell carcinoma (RCC) containing foci of high-grade malignant spindle cells. (medscape.com)
  • Currently, the 2004 WHO classification of renal tumors recognizes this transformation as "sarcomatoid change" or "sarcomatoid features" arising within RCC, rather than as a separate histologic entity. (medscape.com)
  • Tivozanib has been investigated in several tumors types, including renal cell, colorectal and breast cancers. (businesswire.com)
  • Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer and accounts for approximately 60% to 70% of all renal tumors [ 1 ]. (hindawi.com)
  • 2003) Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients. (medscape.org)
  • 2007) Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. (medscape.org)
  • Vermooten V (1950) Indications for conservative surgery in certain renal tumors: a study based on the growth pattern of the cell carcinoma. (medscape.org)
  • RCC, an adenocarcinoma, accounts for 90 to 95% of primary malignant renal tumors. (msdmanuals.com)
  • Percutaneous fine needle aspiration biopsy of the lung via the right anterior chest wall, using a 20 gauge fine needle, showed metastasis from renal cell carcinoma. (cdlib.org)
  • Histological examination of a skin biopsy of the cutaneous nodule revealed features of metastasis from renal cell carcinoma of clear cell type (Figure 2). (cdlib.org)
  • Adding surgery and/or radiation to systemic therapy (multimodal therapy) improved clinical outcomes in patients with renal cell carcinoma (RCC) with brain metastases, reports a university-based research team. (medpagetoday.com)
  • although it is derived from cells of the renal tubular epithelium, it has several histological subtypes which differ in their clinical outcome and biological features. (hindawi.com)
  • Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). (lu.se)
  • Drs Sumeet Bhatia and Eric Jonasch highlight unmet needs in advanced renal cell carcinoma and share clinical pearls. (onclive.com)
  • BACKGROUND: For first-line therapy options for advanced renal cell carcinoma (RCC), clinical trials have demonstrated similar efficacy for pazopanib and sunitinib as well as differing side-effect profiles, which may affect patient persistence in self-administration of these oral medications. (rti.org)
  • Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma. (medscape.com)
  • Guideline for management of the clinical T1 renal mass. (medscape.com)
  • Chromophobe renal cell carcinoma (ChRCC) is the third most common renal cell carcinoma in adults. (lww.com)
  • The most common renal cell carcinoma that develops in patients with end-stage renal disease and acquired cystic disease. (cismef.org)
  • About 9 out of 10 kidney cancers are renal cell carcinomas. (massgeneral.org)
  • The most common non-clear cell renal cancers have also undergone genomic profiling and are characterised by distinct genomic landscapes. (springer.com)
  • The somatic mutational landscape of the more common renal cancers is well known. (springer.com)
  • Correlation with outcome needs to be more comprehensively furnished, particularly for small renal masses, rarer non-clear cell renal cancers, and for all tumours undergoing targeted therapy. (springer.com)
  • Renal cell carcinoma (RCC) accounts for 2% of all cancers. (urotoday.com)
  • The company is focused on developing and commercializing its lead candidate tivozanib, a potent, selective, long half-life inhibitor of vascular endothelial growth factor 1, 2 and 3 receptors, in North America as a treatment for renal cell carcinoma and other cancers. (businesswire.com)
  • Renal cell carcinoma (RCC) is one of the ten most common cancers for men and women with an approximate 75% overall 5-year survival. (frontiersin.org)
  • Renal cell carcinoma is one of the most common cancers in the urinary system, causing over 140,000 deaths worldwide each year[ 1 ]. (medsci.org)
  • A standardized incidence ratio (SIR) was calculated for renal cell and bladder cancers in white males who represented 88% of the PYR. (cdc.gov)
  • Thomas E. Hutson, DO, PharmD, shares insight on the role of combination therapy and recent advances for the management of renal cell carcinoma. (curetoday.com)
  • 2004) Changing concepts in the surgical management of renal cell carcinoma. (medscape.org)
  • 2 cm, the PET/CT agent 89Zr-DFO-girentuximab had respective sensitivity rates of approximately 85 percent and 96.7 percent for diagnosing clear cell renal cell carcinoma, according to research recently presented at the European Association of Nuclear Medicine (EANM) 2023 Congress. (diagnosticimaging.com)
  • Thomas E. Hutson, DO, PharmD, provides insight on the diagnosis of renal cell carcinoma (RCC) and discusses classic signs and symptoms of the disease. (curetoday.com)
  • The study enrolled patients with metastatic clear cell renal cell carcinoma at the time of diagnosis. (ascopost.com)
  • BUN measurements are used in the diagnosis of certain renal and metabolic diseases. (cdc.gov)
  • The test is frequently requested in conjunction with the serum creatinine test for the differential diagnosis of prerenal, renal, and post renal uremia. (cdc.gov)
  • Glucose measurements are used in the diagnosis and treatment of pancreatic islet cell carcinoma and of carbohydrate metabolism disorders, including diabetes mellitus, neonatal hypoglycemia, and idiopathic hypoglycemia. (cdc.gov)
  • Iron (non-heme) measurements are used in the diagnosis and treatment of diseases, such as iron deficiency anemia, chronic renal disease, and hemochromatosis (a disease associated with widespread deposit in the tissues of two iron-containing pigments, hemosiderin and hemofuscin, and characterized by pigmentation of the skin). (cdc.gov)
  • Çalışkan S, Gökçe AM, Gümrükçü G, Önenerk M. Renal Medullary Carcinoma A Rare Entity. (harvard.edu)
  • P.215 2nd paragraph: 'Renal medullary carcinoma (RMC) is a very rare malignancy that accounts for less than 1% of all renal neoplasms [BNID 113715 ]. (harvard.edu)
  • Investigators believe their study is the first to demonstrate the adverse impact of LVI on overall survival in patients with surgically treated renal cell carcinoma. (renalandurologynews.com)
  • Rhabdoid differentiation is found in 3-7.5% of RCCs, most commonly in CCRCC, although rare cases have been reported involving papillary RCC, chromophobe RCC, and collecting duct (Bellini duct) carcinoma. (medscape.com)
  • Clear cell, papillary cell, and chromophobe renal cell carcinomas (RCCs) have now been well characterised thanks to large collaborative projects such as The Cancer Genome Atlas (TCGA). (springer.com)
  • Renal cell carcinomas (RCCs) cause for 80 to 85 percent of all primary renal neoplasm. (scirp.org)
  • The tumour arises from the cells of the proximal renal tubular epithelium. (wikipedia.org)
  • Renal cell carcinoma (RCC) encompasses a group of malignancies that originate in the epithelium of the renal cortex, most often in the upper pole of the kidney. (nih.gov)
  • Prospective evaluation of analgesic use and risk of renal cell cancer. (medscape.com)
  • The risk of renal cell cancer among workers at a paperboard printing and packaging factory was examined. (cdc.gov)
  • A nested case/control study was carried out to determine relationships, if any, between work assignments and risk of renal cell cancer. (cdc.gov)
  • The authors conclude that an excess risk of renal cell cancer is associated with duration of employment, which is not limited to any single work process. (cdc.gov)
  • Cues and clues to renal cell cancer might be found in modifiable or innate patient factors. (medscape.com)
  • Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. (wikipedia.org)
  • When cancer begins in the tissues of a kidney, it is called kidney cancer (or renal cancer). (massgeneral.org)
  • According to the ACS , renal cell carcinoma (also known as renal cell cancer) is "by far the most common type of kidney cancer. (massgeneral.org)
  • Renal cell carcinoma is the most common form of kidney cancer in adults. (pharmacytimes.com)
  • In this review, we consider what is currently known of the genetic landscape of the commonest subtypes of renal cell cancer (RCC). (springer.com)
  • 1] According to the US census and cancer statistics, carcinoma of the kidneys affected approximately 36,160 lives in 2005,[2,3] more than 80% of whom had RCC. (cancernetwork.com)
  • Conventional imaging doesn't provide sufficient clarity for differentiating between benign renal masses and clear cell renal cell carcinoma (ccRCC), "the deadliest renal cancer and the most frequent one," noted Jeremie Calais, M.D, MSc, during an interview at the recent Society of Nuclear Medicine and Molecular Imaging (SNMMI) conference in Chicago . (diagnosticimaging.com)
  • Renal cell carcinoma is a form of kidney cancer that starts in the lining of the small tubes in the kidney. (cancer.gov)
  • for example, Chu and Chen [ 13 ] combined PPI and gene expression data to construct a cancer perturbed PPI network in cervical carcinoma to study gain- and loss-of-function genes as potential drug targets. (hindawi.com)
  • 2004) Application of TNM, 2002 version, in localized renal cell carcinoma: is it able to predict different cancer-specific survival probability? (medscape.org)
  • 2002) Does the size of the surgical margin in partial nephrectomy for renal cell cancer really matter? (medscape.org)
  • Clear cell renal cell carcinoma or CCRCC, is the most common subtype of kidney cancer. (jove.com)
  • Renal cell carcinoma (RCC) is the most common renal cancer. (msdmanuals.com)
  • Renal cell cancer among paperboard printing workers. (cdc.gov)
  • One bladder cancer death, and one renal cancer death were recorded. (cdc.gov)
  • Three workers with bladder cancer (SIR 1.1), and six with renal cell cancer (SIR 3.7) were identified. (cdc.gov)
  • The association between renal cell cancer risk and duration of employment (5yr or more) was not limited to any single department. (cdc.gov)
  • We expose the case of a patient with clear cell type renal cell carcinoma, with a previously known bone metastasis of renal origin and symptomatic goiter containing a nodule that was found to be a metastasic lesion. (scirp.org)
  • We expose the case of a patient with clear cell type renal cell carcinoma, thyroid metastasis with a previously known bone metastasis of renal origin and large goiter with compressive symptoms. (scirp.org)
  • For the ZIRCON study, researchers assessed the use of 89 ZR-DFO-girentuximab (TLX250-CDx, Telix Pharmaceuticals) for ccRCC detection in adult patients with indeterminate renal masses. (diagnosticimaging.com)
  • Metastasis of clear cell renal cell carcinoma (ccRCC) to the thyroid gland is rare, and simultaneous occurrence of ccRCC and papillary thyroid carcinoma (PTC) is even rarer. (spandidos-publications.com)
  • However, thyroid metastasis of ccRCC combined with papillary thyroid carcinoma (PTC) is rarely reported. (spandidos-publications.com)
  • In this mouse model, heterogeneous CCRCC is implanted to the renal capsule of the mouse. (jove.com)
  • The control group consisted of 10 consecutive patients with 11 spinal metastases of renal carcinoma, which were treated surgically without preoperative embolization between April 1994 and April 1997. (ajnr.org)
  • A retrospective study revealed no significant difference in 36-month progression-free survival and renal function outcomes in patients with small renal masses. (renalandurologynews.com)
  • These investigators examined hereditary predisposition syndromes related to the co-occurrence of melanoma and/or mesothelioma with renal cell carcinoma and their germline associations with BAP1, FLCN, and MITF p.E318K alterations. (medpagetoday.com)
  • A renal mass of indeterminate etiology should be monitored periodically by imaging study such as intravenous pyelography (IVP), ultrasonography, or computed tomography (CT) scanning. (medscape.com)
  • Treatment protocols for renal cell carcinoma are provided below, including treatment of localized and advanced disease and recommendations for patients with predominantly clear cell carcinoma and those with predominantly non-clear cell carcinoma. (medscape.com)
  • Go to Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma for more complete information on these topics. (medscape.com)
  • Sternal biopsy was compatible with metastases from clear cell renal carcinoma ( Figure 1 ). (scirp.org)
  • The anatomopathological analysis of the surgical specimen described micrometastasis by clear cell renal carcinoma. (scirp.org)
  • In an interview at the recent Society of Nuclear Medicine and Molecular Imaging (SNMMI) conference in Chicago, Jeremie Calais, M.D., MSc discussed promising research findings for the use of the positron emission tomography (PET) imaging agent 89ZR-DFO-girentuximab for diagnosing clear cell renal cell carcinoma. (diagnosticimaging.com)
  • Editor's note: For related content, see " Emerging PET/CT Imaging Agent Shows Promise for Diagnosing Clear Cell Renal Cell Carcinoma . (diagnosticimaging.com)
  • The patient underwent right nephrectomy and histopathology evaluation confirmed renal cell carcinoma (clear cell type). (radiopaedia.org)
  • Histological examination of the surgical specimen revealed clear cell renal carcinoma pT2 N0. (cdlib.org)
  • In aggregate, all studies to date were negative, with the exception of the phase III S-TRAC study, which tested the adjuvant use of sunitinib in patients with locally advanced (pT3-4) or node-positive clear cell renal cell carcinoma. (ascopost.com)
  • Although the ASSURE trial enrolled a heterogeneous patient population, including those with either clear cell or variant histology renal cell carcinoma and either pT1b grade 3-4, pT2-T4, or node-positive disease, subset analyses in patients with clear cell renal cell carcinoma with pT3-4 or node-positive disease failed to demonstrate a benefit with adjuvant sunitinib. (ascopost.com)
  • The KEYNOTE-564 study was a phase III, double-blind, randomized, placebo-controlled trial testing the efficacy of pembrolizumab vs placebo as adjuvant therapy for patients with clear cell renal cell carcinoma at high risk of recurrence following definitive nephrectomy. (ascopost.com)
  • If they are offended at this time, then the promotion and publicity of popular brands in the Cannabis Oil Renal Cell Carcinoma a good Cbd Ecommerce Site For Sale be clear about what the public did Although these guys' articles were a bit exaggerated, they didn't tell cbd gummies what are they. (segel-berichte.de)
  • Metastatic clear cell renal cell carcinoma is a disease without a comprehensive animal model for thorough preclinical investigation. (jove.com)
  • Sarcomatoid conversion of clear cell renal cell carcinoma in relation to epithelial-to-mesenchymal transition. (lu.se)
  • Approximately 8% of clear cell renal cell carcinoma cases contain regions of radically different morphology, demonstrating a mesenchymal appearance histologically resembling sarcomas. (lu.se)
  • Patients diagnosed with sarcomatoid clear cell renal cell carcinoma face a considerably worse prognosis due to an increased propensity for metastasis. (lu.se)
  • In the present study we investigate whether the sarcomatoid conversion of clear cell renal cell carcinoma could be interpreted as linked to the process of epithelial-mesenchymal transition. (lu.se)
  • Furthermore the sarcomatoid elements demonstrate an enhanced expression of epithelial-mesenchymal transition related mesenchymal markers as compared with the clear cell renal cell carcinoma counterparts. (lu.se)
  • We further selected a representative case, clinically demonstrating direct overgrowth of the sarcomatoid component into the liver and colon, for extended immunohistochemical characterization, resulting in a further set of positive and negative epithelial-mesenchymal transition markers as well as pronounced transforming growth factor β positivity, indicating that sarcomatoid clear cell renal cell carcinoma may be associated to epithelial-mesenchymal transition. (lu.se)
  • Transforming growth factor β1 exposure of in vitro cultured primary clear cell renal cell carcinoma cells resulted in cells adopting a mesenchymal morphology similar to sarcomatoid clear cell renal cell carcinoma. (lu.se)
  • We therefore suggest that sarcomatoid clear cell renal cell carcinoma morphologically and immunohistochemically may represent a completed epithelial-mesenchymal transition and that transforming growth factor β1 could be an important driving force during the sarcomatoid transdifferentiation of clear cell renal cell carcinoma. (lu.se)
  • The ongoing phase III ADAPT (The Autologous Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma) study is using this approach to personalized immunotherapy, with the goal of randomizing 450 patients. (urologytimes.com)
  • The KEYNOTE-564 study is the first positive adjuvant immunotherapy trial in patients with resected renal cell carcinoma and presents an advancement in the care of these patients. (ascopost.com)
  • 7 The study, which was reported in The New England Journal of Medicine by Choueiri et al and is summarized in this issue of The ASCO Post , is the first positive adjuvant immunotherapy trial in patients with resected renal cell carcinoma and represents an advancement in the care of these patients. (ascopost.com)
  • I think there is a great need for more education on the use of nivolumab-ipilimumab, especially because I've seen patients with good-risk metastatic RCC [renal cell carcinoma] who have been treated with that regimen, which I think is inappropriate. (onclive.com)
  • The first checkpoint inhibitor approved for renal cell carcinoma was nivolumab in 2015, based on the results of the phase III CheckMate 025 study testing the efficacy of nivolumab vs everolimus in patients having received prior VEGF-targeting therapy. (ascopost.com)
  • The concept of eosinophilic ChRCC has significantly evolved, yet it still is one of the major diagnostic challenges pathologists face in routine practice due to its morphologic overlap with renal oncocytoma. (lww.com)
  • Renal & Urology News publishes timely news coverage of scientific developments of interest to nephrologists and urologists, including in-depth coverage of all relevant medical conferences. (renalandurologynews.com)
  • CAMBRIDGE, Mass.--( BUSINESS WIRE )--AVEO Oncology (NASDAQ:AVEO) today announced that the first patient has been dosed in the Company's pivotal TIVO-3 trial, a randomized, controlled, multi-center, open-label study to compare tivozanib to sorafenib in subjects with refractory advanced renal cell carcinoma (RCC). (businesswire.com)
  • An enlarged lymph node with SAD of 9 mm is present in the paracaval region adjacent to the renal hilum. (radiopaedia.org)
  • See Renal Cell Carcinoma: Recognition and Follow-up , a Critical Images slideshow, to help evaluate renal masses and determine when and what type of follow-up is necessary. (medscape.com)
  • 2005) Exploring the learning curve, pathological outcomes and perioperative morbidity of laparoscopic partial nephrectomy performed for renal mass. (medscape.org)
  • 2007) Patterns of recurrence and surveillance strategies for renal cell carcinoma following surgical resection. (medscape.org)
  • The results of the S-TRAC trial contrasted with those of the large phase III ASSURE trial, which tested the efficacy of sunitinib vs sorafenib vs placebo in patients with renal cell carcinoma at high risk of recurrence. (ascopost.com)
  • An updated analysis of the phase 3 KEYNOTE-564 trial (NCT03142334) found that adjuvant treatment with pembrolizumab (Keytruda) continued to demonstrate improved disease-free survival (DFS) vs placebo in patients with renal cell carcinoma (RCC) who are at high risk of recurrence. (urologytimes.com)
  • We found that exposure of renal adenocarcinoma cells to hypoxia induced EV secretion and led to notable changes in the EV protein cargo in comparison to normoxia. (timegate.com)